KR20160030876A - 약제학적 활성 성분들로써 뉴클레오시드 유사체들의 생물촉매적 생산 - Google Patents
약제학적 활성 성분들로써 뉴클레오시드 유사체들의 생물촉매적 생산 Download PDFInfo
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- KR20160030876A KR20160030876A KR1020157030620A KR20157030620A KR20160030876A KR 20160030876 A KR20160030876 A KR 20160030876A KR 1020157030620 A KR1020157030620 A KR 1020157030620A KR 20157030620 A KR20157030620 A KR 20157030620A KR 20160030876 A KR20160030876 A KR 20160030876A
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
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- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/38—Nucleosides
- C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/02—Pentosyltransferases (2.4.2)
- C12Y204/02006—Nucleoside deoxyribosyltransferase (2.4.2.6)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
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- Bioinformatics & Cheminformatics (AREA)
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- General Engineering & Computer Science (AREA)
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- General Chemical & Material Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361817064P | 2013-04-29 | 2013-04-29 | |
| US61/817,064 | 2013-04-29 | ||
| PCT/EP2014/058761 WO2014177585A2 (en) | 2013-04-29 | 2014-04-29 | Biocatalytic production of nucleoside analogues as active pharmaceutical ingredients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20160030876A true KR20160030876A (ko) | 2016-03-21 |
Family
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| KR1020157030620A Withdrawn KR20160030876A (ko) | 2013-04-29 | 2014-04-29 | 약제학적 활성 성분들로써 뉴클레오시드 유사체들의 생물촉매적 생산 |
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| Country | Link |
|---|---|
| US (1) | US10184142B2 (enExample) |
| EP (1) | EP2992107B1 (enExample) |
| JP (1) | JP2016518838A (enExample) |
| KR (1) | KR20160030876A (enExample) |
| CA (1) | CA2905306A1 (enExample) |
| WO (1) | WO2014177585A2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2937420A1 (en) * | 2014-04-23 | 2015-10-28 | Synbias Pharma AG | Method for the synthesis of clofarabine |
| JP2016198075A (ja) * | 2015-04-14 | 2016-12-01 | プラズミア バイオテック，エス．エル． | シトシンヌクレオシドアナログの酵素産生 |
| CN106191172A (zh) * | 2015-05-06 | 2016-12-07 | 普拉斯米亚生物技术有限公司 | 胞嘧啶核苷类似物的酶法制备 |
| EP3115461A1 (en) * | 2015-07-07 | 2017-01-11 | Synbias Pharma AG | Method for the synthesis of pentostatin |
| BR112018002399A2 (pt) | 2015-08-06 | 2018-09-25 | Chimerix, Inc. | nucleosídeos de pirrolopirimidina e análogos dos mesmos, úteis como agentes antivirais |
| EP3684771B1 (en) | 2017-09-21 | 2024-11-27 | Chimerix, Inc. | Morphic forms of 4-amino-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methyl-7h-pyrrolo(2,3-d)pyrimidine-5-carboxamide and uses thereof |
| CN115109814B (zh) * | 2022-08-26 | 2022-11-29 | 常熟药明康德新药开发有限公司 | 一种制备2’-脱氧-2’-氟-β-D-阿拉伯糖腺苷类似物的方法 |
| CN116064703A (zh) * | 2022-10-21 | 2023-05-05 | 凯莱英生命科学技术(天津)有限公司 | 酶催化合成含有保护基的核苷的方法及组合物 |
| CN115725535B (zh) * | 2022-11-30 | 2023-06-06 | 杭州珲益生物科技有限公司 | 一种n-脱氧核糖转移酶及其在脱氧核苷制备中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4211773A (en) * | 1978-10-02 | 1980-07-08 | Sloan Kettering Institute For Cancer Research | 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides |
| KR20020048930A (ko) | 1999-08-20 | 2002-06-24 | 로셰 디아그노스틱스 게엠베하 | 데옥시리보뉴클레오시드의 효소적 합성 |
| US7892838B2 (en) * | 2003-03-28 | 2011-02-22 | Institut Pasteur | Method for the in vivo modification of the synthesis activity of a metabolite by means of the modification of a gene the activity of which is not the original activity |
| EP2917341B1 (en) * | 2012-11-08 | 2017-09-27 | Centre National de la Recherche Scientifique (CNRS) | New phosphodeoxyribosyltransferase mutant enzymes and uses thereof |
-
2014
- 2014-04-29 US US14/787,678 patent/US10184142B2/en not_active Expired - Fee Related
- 2014-04-29 KR KR1020157030620A patent/KR20160030876A/ko not_active Withdrawn
- 2014-04-29 JP JP2016511045A patent/JP2016518838A/ja active Pending
- 2014-04-29 CA CA2905306A patent/CA2905306A1/en not_active Abandoned
- 2014-04-29 WO PCT/EP2014/058761 patent/WO2014177585A2/en not_active Ceased
- 2014-04-29 EP EP14725646.5A patent/EP2992107B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2905306A1 (en) | 2014-11-06 |
| JP2016518838A (ja) | 2016-06-30 |
| EP2992107B1 (en) | 2019-12-11 |
| WO2014177585A2 (en) | 2014-11-06 |
| WO2014177585A3 (en) | 2015-01-22 |
| US20160076070A1 (en) | 2016-03-17 |
| US10184142B2 (en) | 2019-01-22 |
| EP2992107A2 (en) | 2016-03-09 |
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