JP2014514921A5 - - Google Patents
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- Publication number
- JP2014514921A5 JP2014514921A5 JP2014501947A JP2014501947A JP2014514921A5 JP 2014514921 A5 JP2014514921 A5 JP 2014514921A5 JP 2014501947 A JP2014501947 A JP 2014501947A JP 2014501947 A JP2014501947 A JP 2014501947A JP 2014514921 A5 JP2014514921 A5 JP 2014514921A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- nucleic acid
- acid molecule
- functional nucleic
- molecule according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108020004707 nucleic acids Proteins 0.000 claims 19
- 102000039446 nucleic acids Human genes 0.000 claims 19
- 150000007523 nucleic acids Chemical class 0.000 claims 19
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 12
- 230000014616 translation Effects 0.000 claims 12
- 238000001243 protein synthesis Methods 0.000 claims 11
- 108020004414 DNA Proteins 0.000 claims 9
- 108090000623 proteins and genes Proteins 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 102000053602 DNA Human genes 0.000 claims 4
- 238000000034 method Methods 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 108091081024 Start codon Proteins 0.000 claims 2
- 230000000692 anti-sense effect Effects 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000001105 regulatory effect Effects 0.000 claims 2
- 108020003589 5' Untranslated Regions Proteins 0.000 claims 1
- 108091023045 Untranslated Region Proteins 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161469399P | 2011-03-30 | 2011-03-30 | |
| US61/469,399 | 2011-03-30 | ||
| PCT/JP2012/059430 WO2012133947A1 (en) | 2011-03-30 | 2012-03-30 | Functional nucleic acid molecule and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017083227A Division JP6770921B2 (ja) | 2011-03-30 | 2017-04-19 | 機能性核酸分子、及びその利用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014514921A JP2014514921A (ja) | 2014-06-26 |
| JP2014514921A5 true JP2014514921A5 (enExample) | 2015-05-14 |
Family
ID=46931619
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014501947A Pending JP2014514921A (ja) | 2011-03-30 | 2012-03-30 | 機能性核酸分子、及びその利用 |
| JP2017083227A Active JP6770921B2 (ja) | 2011-03-30 | 2017-04-19 | 機能性核酸分子、及びその利用 |
| JP2020162110A Active JP7229487B2 (ja) | 2011-03-30 | 2020-09-28 | 機能性ｒｎａ分子、及びその利用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017083227A Active JP6770921B2 (ja) | 2011-03-30 | 2017-04-19 | 機能性核酸分子、及びその利用 |
| JP2020162110A Active JP7229487B2 (ja) | 2011-03-30 | 2020-09-28 | 機能性ｒｎａ分子、及びその利用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9353370B2 (enExample) |
| EP (2) | EP2691522B1 (enExample) |
| JP (3) | JP2014514921A (enExample) |
| ES (1) | ES2855577T3 (enExample) |
| WO (1) | WO2012133947A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105624156B (zh) * | 2014-11-04 | 2021-07-16 | 清华大学 | 含有反向sineb2重复序列的人工非编码rna及其在增强靶蛋白翻译中的用途 |
| IT201700105372A1 (it) | 2017-09-20 | 2019-03-20 | Fondazione St Italiano Tecnologia | Molecola di acido nucleico funzionale e relativo uso |
| IT201800002411A1 (it) * | 2018-02-05 | 2019-08-05 | Scuola Int Superiore Di Studi Avanzati Sissa | Domini strutturali di molecole di rna antisenso che aumentano la traduzione |
| IT201900011490A1 (it) | 2019-07-11 | 2021-01-11 | Scuola Int Superiore Di Studi Avanzati Sissa | MOLECOLE DI ACIDO NUCLEICO FUNZIONALI CHE AUMENTANO LA TRADUZIONE DI UN mRNA DELLA FRATASSINA |
| KR20220097875A (ko) | 2019-09-03 | 2022-07-08 | 마이얼로이드 테라퓨틱스, 인크. | 게놈 통합을 위한 방법 및 조성물 |
| KR20230128446A (ko) * | 2020-09-24 | 2023-09-05 | 폰다치오네 이스티튜토 이탈리아노 디 테크놀로지아 | 변형된 기능적 핵산 분자 |
| EP4225916A1 (en) | 2020-10-08 | 2023-08-16 | Transine Therapeutics Limited | Functional nucleic acid molecules |
| EP3992289A1 (en) | 2020-10-30 | 2022-05-04 | Transine Therapeutics Limited | Functional nucleic acid molecules incorporating protein binding domain |
| WO2022154107A1 (ja) | 2021-01-18 | 2022-07-21 | イビデン株式会社 | 組電池用熱伝達抑制シート及び組電池 |
| EP4063505A1 (en) | 2021-03-22 | 2022-09-28 | Fondazione Istituto Italiano di Tecnologia | Functional nucleic acid molecules directed to targets for nervous system disorders |
| WO2022214635A1 (en) | 2021-04-08 | 2022-10-13 | Stichting Vu | Nucleic acid molecules for compensation of stxbp1 haploinsufficiency and their use in the treatment of stxbp1-related disorders |
| EP4337268A4 (en) | 2021-05-11 | 2025-06-04 | Myeloid Therapeutics, Inc. | Methods and compositions for genomic integration |
| GB202205423D0 (en) | 2022-04-12 | 2022-05-25 | Transine Therapeutics Ltd | Functional nucleic acid molecule |
| GB202207795D0 (en) | 2022-05-26 | 2022-07-13 | Fondazione St Italiano Tecnologia | Functional nucleic acid molecule |
| GB202207796D0 (en) | 2022-05-26 | 2022-07-13 | Fondazione St Italiano Tecnologia | Functional nucleic acid molecule |
| IT202200011546A1 (it) | 2022-06-01 | 2022-09-01 | Univ Degli Studi Di Trento | Sequenze di RNA non codificanti in grado di aumentare l'espressione delle proteine CHD8 e CHD2 |
| WO2025133858A1 (en) | 2023-12-18 | 2025-06-26 | Fondazione Istituto Italiano Di Tecnologia | Functional nucleic acid molecule capable of increasing bdnf production |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| EP2314688B1 (en) * | 2004-11-12 | 2014-07-16 | Asuragen, Inc. | Methods and compositions involving miRNA and miRNA inhibitor molecules |
| KR101420740B1 (ko) | 2005-12-13 | 2014-07-17 | 교또 다이가꾸 | 핵초기화 인자 |
| WO2008113773A2 (en) | 2007-03-16 | 2008-09-25 | Biorigen S.R.L. | Gene expression regulation technology and noncoding rnas for diagnosis and therapy |
| EP2235180B1 (en) * | 2007-12-28 | 2011-11-09 | Qiagen Sciences, Inc. | Apoptosis inducing positive control for expression modulating experiments |
| US20110003365A1 (en) | 2009-05-29 | 2011-01-06 | Kyoto University | Method of preparing induced pluripotent stem cells deprived of reprogramming gene |
| JP5696282B2 (ja) | 2009-06-10 | 2015-04-08 | 国立大学法人京都大学 | 人工多能性幹細胞樹立効率改善剤 |
| JP2011004674A (ja) | 2009-06-26 | 2011-01-13 | Fujitsu Ltd | 誘導多能性幹細胞（ｉＰＳ細胞）の製造方法 |
| JP5751548B2 (ja) | 2009-08-07 | 2015-07-22 | 国立大学法人京都大学 | イヌｉＰＳ細胞及びその製造方法 |
-
2012
- 2012-03-30 JP JP2014501947A patent/JP2014514921A/ja active Pending
- 2012-03-30 ES ES12763652T patent/ES2855577T3/es active Active
- 2012-03-30 US US14/008,186 patent/US9353370B2/en active Active
- 2012-03-30 EP EP12763652.0A patent/EP2691522B1/en active Active
- 2012-03-30 WO PCT/JP2012/059430 patent/WO2012133947A1/en not_active Ceased
- 2012-03-30 EP EP20203177.9A patent/EP3792359A1/en active Pending
-
2017
- 2017-04-19 JP JP2017083227A patent/JP6770921B2/ja active Active
-
2020
- 2020-09-28 JP JP2020162110A patent/JP7229487B2/ja active Active
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