JP2007525157A - 肺炎連鎖球菌抗原 - Google Patents

肺炎連鎖球菌抗原 Download PDF

Info

Publication number
JP2007525157A
JP2007525157A JP2006505135A JP2006505135A JP2007525157A JP 2007525157 A JP2007525157 A JP 2007525157A JP 2006505135 A JP2006505135 A JP 2006505135A JP 2006505135 A JP2006505135 A JP 2006505135A JP 2007525157 A JP2007525157 A JP 2007525157A
Authority
JP
Japan
Prior art keywords
seq
nucleic acid
hyperimmune serum
serum reactive
acid molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006505135A
Other languages
English (en)
Japanese (ja)
Inventor
アンドレアス・マインケ
エステル・ナデュ
マルクス・ハンナー
シャイレシュ・デワスタリー
ウルリケ・シュティーアシュナイダー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valneva Austria GmbH
Original Assignee
Intercell Austria AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intercell Austria AG filed Critical Intercell Austria AG
Publication of JP2007525157A publication Critical patent/JP2007525157A/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2006505135A 2003-04-15 2004-04-15 肺炎連鎖球菌抗原 Pending JP2007525157A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03450087 2003-04-15
PCT/EP2004/003984 WO2004092209A2 (en) 2003-04-15 2004-04-15 S. pneumoniae antigens

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010174020A Division JP2011004753A (ja) 2003-04-15 2010-08-02 肺炎連鎖球菌抗原

Publications (1)

Publication Number Publication Date
JP2007525157A true JP2007525157A (ja) 2007-09-06

Family

ID=33186037

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2006505135A Pending JP2007525157A (ja) 2003-04-15 2004-04-15 肺炎連鎖球菌抗原
JP2010174020A Pending JP2011004753A (ja) 2003-04-15 2010-08-02 肺炎連鎖球菌抗原
JP2012099977A Pending JP2012184236A (ja) 2003-04-15 2012-04-25 肺炎連鎖球菌抗原

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2010174020A Pending JP2011004753A (ja) 2003-04-15 2010-08-02 肺炎連鎖球菌抗原
JP2012099977A Pending JP2012184236A (ja) 2003-04-15 2012-04-25 肺炎連鎖球菌抗原

Country Status (7)

Country Link
US (3) US7635487B2 (enExample)
EP (11) EP1615950A2 (enExample)
JP (3) JP2007525157A (enExample)
CN (2) CN1774447B (enExample)
AU (1) AU2004230244B2 (enExample)
CA (1) CA2522238A1 (enExample)
WO (1) WO2004092209A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011511275A (ja) * 2008-02-01 2011-04-07 サノフィ パストゥール リミテッド 診断的アッセイ
JP2011514167A (ja) * 2008-03-17 2011-05-06 インターセル アーゲー 肺炎連鎖球菌(S.pneumoniae)に対して保護的なペプチドならびにそれに関連する組成物、方法、および使用
JP2012532134A (ja) * 2009-06-29 2012-12-13 ジェノセア バイオサイエンシーズ, インコーポレイテッド StreptococcusPneumoniaeに対するワクチンおよび組成物
JP2013525271A (ja) * 2010-03-12 2013-06-20 チルドレンズ メディカル センター コーポレーション 免疫原およびそのスクリーニング方法
US12036276B2 (en) 2021-09-09 2024-07-16 Affinivax, Inc. Multivalent pneumococcal vaccines

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800744B1 (en) * 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
AU2002351623A1 (en) 2001-12-20 2003-07-09 Shire Biochem Inc. Streptococcus antigens
CN1909921B (zh) * 2003-11-10 2012-09-26 Uab研究基金会 减少细菌携带和中枢神经系统侵害的组合物及其使用方法
EP2059807B1 (en) * 2006-08-17 2013-02-20 The UAB Research Foundation Diagnosing pneumococcal pneumonia
WO2008039838A2 (en) * 2006-09-27 2008-04-03 St. Jude Children's Research Hospital Synthetic streptococcus pneumoniae vaccine
EP1923069A1 (en) 2006-11-20 2008-05-21 Intercell AG Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto
EP2164957B1 (en) * 2007-05-23 2017-07-12 The UAB Research Foundation Detoxified pneumococcal neuraminidase and uses thereof
WO2008146164A2 (en) * 2007-05-25 2008-12-04 Novartis Ag Streptococcus pneumoniae pilus antigens
AU2008280799B2 (en) * 2007-07-23 2013-07-11 Sanofi Pasteur Limited Immunogenic polypeptides and monoclonal antibodies
US20160228500A9 (en) * 2007-07-23 2016-08-11 Martina Ochs Immunogenic Polypeptides and Monoclonal Antibodies
GB0714963D0 (en) * 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
DK2268618T3 (en) 2008-03-03 2015-08-17 Novartis Ag Compounds and compositions as TLR aktivitetsmodulatorer
EP2108656A1 (en) * 2008-03-19 2009-10-14 Beninati, Concetta Antigenic protein fragments of streptococcus pneumoniae
US8348429B2 (en) 2008-03-27 2013-01-08 Doheny Eye Institute Optical coherence tomography device, method, and system
US11839430B2 (en) 2008-03-27 2023-12-12 Doheny Eye Institute Optical coherence tomography-based ophthalmic testing methods, devices and systems
WO2009143483A2 (en) * 2008-05-22 2009-11-26 The Board Of Regents Of The University Of Texas System PsrP IS A PROTECTIVE ANTIGEN AGAINST PNEUMOCOCCAL INFECTION
WO2010009450A1 (en) 2008-07-18 2010-01-21 Doheny Eye Institute Optical coherence tomography device, method, and system
ES2352704B1 (es) * 2008-08-08 2012-06-14 CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)(Titular al 80%) Secuencia de nucleotido y proteina b-galactosidasa de streptococcus mitis, procedimiento de obtencion y sus aplicaciones.
WO2010025584A1 (zh) * 2008-09-04 2010-03-11 Wang Lei 表达发卡rna的dna分子及其构建方法和应用
WO2010029546A2 (en) * 2008-09-11 2010-03-18 Ben Gurion University Of The Negev Research And Development Authority Compositions and methods for treating s.pneumoniae infection
ATE523204T1 (de) 2009-02-16 2011-09-15 Karlsruher Inst Technologie Cd44v6-peptide als bakterielle infektionsinhibitoren
US20120064103A1 (en) 2009-03-24 2012-03-15 Novartis Ag Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates
EP2440245B1 (en) 2009-06-10 2017-12-06 GlaxoSmithKline Biologicals SA Benzonaphthyridine-containing vaccines
TWI445708B (zh) 2009-09-02 2014-07-21 Irm Llc 作為tlr活性調節劑之化合物及組合物
SG178954A1 (en) 2009-09-02 2012-04-27 Novartis Ag Immunogenic compositions including tlr activity modulators
AU2010293902A1 (en) 2009-09-10 2012-03-22 Novartis Ag Combination vaccines against respiratory tract diseases
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
MX339146B (es) 2009-12-15 2016-05-13 Novartis Ag Suspension homogenea de compuestos inmunopotenciadores y usos de los mismos.
EP2549990A1 (en) 2010-03-23 2013-01-30 Irm Llc Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc.
WO2012072769A1 (en) 2010-12-01 2012-06-07 Novartis Ag Pneumococcal rrgb epitopes and clade combinations
JP6046632B2 (ja) 2010-12-03 2016-12-21 サノフィ パストゥール リミテッドSanofi Pasteur Limited 肺炎球菌に対する免疫用組成物
SG10201600435UA (en) 2011-01-20 2016-02-26 Genocea Biosciences Inc Vaccines And Compositions Against Streptococcus Pneumoniae
JP6366501B2 (ja) 2011-05-11 2018-08-01 ザ チルドレンズ メディカル センター コーポレーション 修飾ビオチン結合タンパク質、その融合タンパク質、および用途
CN104080479B (zh) 2011-11-07 2019-11-05 葛兰素史密丝克莱恩生物有限公司 包括spr0096和spr2021抗原的运载体分子
MX2014010011A (es) * 2012-02-24 2014-09-08 Novartis Ag Proteinas y composiciones de pilus.
EP2822586A1 (en) 2012-03-07 2015-01-14 Novartis AG Adjuvanted formulations of streptococcus pneumoniae antigens
US10124051B2 (en) 2012-05-22 2018-11-13 Glaxosmithkline Biologicals Sa Meningococcus serogroup X conjugate
RU2510281C2 (ru) 2012-06-22 2014-03-27 Общество с ограниченной ответственностью "Эпитоп" (ООО "Эпитоп") ВАКЦИНА ПРОТИВ ПНЕВМОНИИ, ВЫЗЫВАЕМОЙ Streptococcus pneumoniae, НА ОСНОВЕ ГИБРИДНОГО БЕЛКА
WO2014018904A1 (en) * 2012-07-26 2014-01-30 Genocea Biosciences, Inc. Fused antigen vaccines and compositions against streptococcus pneumoniae
CN105188747A (zh) 2013-02-01 2015-12-23 葛兰素史密斯克莱生物公司 包含toll样受体激动剂的免疫组合物的皮内递送
ES2959258T3 (es) 2013-02-07 2024-02-22 Childrens Medical Center Antígenos proteicos que proporcionan protección contra la colonización y/o la enfermedad neumocócicas
US10772497B2 (en) 2014-09-12 2020-09-15 Envision Diagnostics, Inc. Medical interfaces and other medical devices, systems, and methods for performing eye exams
US9226856B2 (en) 2013-03-14 2016-01-05 Envision Diagnostics, Inc. Inflatable medical interfaces and other medical devices, systems, and methods
JPWO2016204265A1 (ja) * 2015-06-18 2018-06-14 一般財団法人阪大微生物病研究会 肺炎球菌補体依存性殺菌能測定方法
US11039741B2 (en) 2015-09-17 2021-06-22 Envision Diagnostics, Inc. Medical interfaces and other medical devices, systems, and methods for performing eye exams
WO2017190087A1 (en) 2016-04-30 2017-11-02 Envision Diagnostics, Inc. Medical devices, systems, and methods for performing eye exams and eye tracking
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
WO2018175783A1 (en) * 2017-03-22 2018-09-27 Modernatx, Inc. Rna bacterial vaccines
WO2018183475A1 (en) 2017-03-28 2018-10-04 Children's Medical Center Corporation A multiple antigen presenting system (maps)-based staphylococcus aureus vaccine, immunogenic composition, and uses thereof
ES2967001T3 (es) 2017-06-23 2024-04-25 Affinivax Inc Composiciones inmunogénicas
EP3752182B1 (en) 2018-02-12 2024-05-15 Inimmune Corporation Toll-like receptor ligands
GB201807380D0 (en) * 2018-05-04 2018-06-20 Karlsson Roger Biomarkers for detecting microbial infection
WO2020056202A1 (en) 2018-09-12 2020-03-19 Affinivax, Inc. Multivalent pneumococcal vaccines
JP7535791B2 (ja) 2018-09-12 2024-08-19 ザ チルドレンズ メディカル センター コーポレーション 肺炎球菌融合タンパク質ワクチン
RU2701733C1 (ru) * 2018-12-14 2019-10-01 Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") Живая вакцина на основе штамма пробиотиков ENTEROCOCCUS FAECIUM L3 для профилактики инфекции, вызванной STREPTOCOCCUS PNEUMONIE
CN111748535B (zh) * 2019-03-28 2022-07-05 安徽华恒生物科技股份有限公司 一种丙氨酸脱氢酶突变体及其在发酵生产l-丙氨酸中的应用
KR20230117105A (ko) 2020-11-04 2023-08-07 엘리고 바이오사이언스 큐티박테리움 아크네스 재조합 파지, 그의 제조 방법 및 용도
GB202100097D0 (en) * 2021-01-05 2021-02-17 Univ Liverpool Novel composition
TW202413403A (zh) * 2022-06-07 2024-04-01 北京大學第一醫院 包含IgA蛋白酶截短體的融合蛋白及其用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002077021A2 (en) * 2001-03-27 2002-10-03 Chiron Srl. Streptococcus pneumoniae proteins and nucleic acids
JP2002533123A (ja) * 1998-12-23 2002-10-08 シャイアー・バイオケム・インコーポレイテッド 新規連鎖球菌抗原

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US40000A (en) 1863-09-15 Improvement in sewing-machines
US4609231A (en) 1984-12-24 1986-09-02 Perfectdata Corporation Floppy diskette storage container
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
ATE318832T1 (de) 1990-06-11 2006-03-15 Gilead Sciences Inc Verfahren zur vervendung von nukleinsäureliganden
DE59109269D1 (de) 1990-06-28 2005-12-15 Hoechst Ag Fusionsproteine mit Immunglobulinanteilen, ihre Herstellung und Verwendung
DE69232871T2 (de) 1991-06-24 2003-05-08 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Polypeptide des hepatitis c-virus (hiv)
DK0772619T4 (da) 1994-07-15 2011-02-21 Univ Iowa Res Found Immunmodulatoriske oligonukleotider
CZ394297A3 (cs) * 1995-06-07 1998-04-15 Biochem Vaccines Inc. Streptokokové proteiny teplotního šoku ze skupiny HSP70
CO4600681A1 (es) 1996-02-24 1998-05-08 Boehringer Ingelheim Pharma Composicion farmaceutica para la modulacion inmunitaria
US6605713B1 (en) 1996-08-30 2003-08-12 Jens Peter Furste Mirror-symmetrical selection and evolution of nucleic acids
US5989912A (en) 1996-11-21 1999-11-23 Oligos Etc. Inc. Three component chimeric antisense oligonucleotides
US5849902A (en) 1996-09-26 1998-12-15 Oligos Etc. Inc. Three component chimeric antisense oligonucleotides
DE69739981D1 (de) * 1996-10-31 2010-10-14 Human Genome Sciences Inc Streptococcus pneumoniae-Antigene und Impfstoffe
JP2001510989A (ja) * 1996-11-01 2001-08-07 スミスクライン・ビーチャム・コーポレイション 新規コーディング配列
US6071724A (en) * 1996-12-13 2000-06-06 Eli Lilly And Company Streptococcus pneumoniaegene sequence era
US6800744B1 (en) * 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
DE19803453A1 (de) 1998-01-30 1999-08-12 Boehringer Ingelheim Int Vakzine
EP1144640A3 (en) * 1998-07-27 2001-11-28 Microbial Technics Limited Nucleic acids and proteins from streptococcus pneumoniae
EP1100921B1 (en) * 1998-07-27 2007-05-02 Sanofi Pasteur Limited Streptococcus pneumoniae proteins and nucleic acid molecules
US6951652B2 (en) * 1998-07-29 2005-10-04 Biosynth S.R.L. Vaccine for prevention of gram-negative bacterial infections and endotoxin related diseases
WO2000029434A2 (en) * 1998-11-19 2000-05-25 St. Jude Children's Research Hospital PNEUMOCOCCAL CHOLINE BINDING PROTEINS, CbpG AND CbpD, DIAGNOSTIC AND THERAPEUTIC USES THEREOF
AT408721B (de) 1999-10-01 2002-02-25 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung enthaltend ein antigen
EP1261630A2 (en) * 1999-12-30 2002-12-04 Bristol-Myers Squibb Company Bacterial genes and proteins that are essential for cell viability and their uses
AT409085B (de) 2000-01-28 2002-05-27 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen
DE60130877T2 (de) 2000-04-14 2008-07-17 Intercell Ag Modifizierte peptide enthaltende pharmazeutische präparationen
AT410173B (de) 2000-06-08 2003-02-25 Cistem Biotechnologies Gmbh Antigene zusammensetzung
HU228264B1 (en) 2000-06-08 2013-02-28 Intercell Ag Immunostimulatory oligodeoxynucleotides
WO2002005448A1 (en) 2000-07-10 2002-01-17 Telefonaktiebolaget Lm Ericsson (Publ) Resource management in uncoordinated frequency hopping system
WO2002013857A2 (en) 2000-08-17 2002-02-21 Intercell Biomedizinische Forschungs- Und Entwicklungs Ag A vaccine which comprises at least one antigen and a cathelididin derived antimicrobial peptide or a derivative thereof
AT410635B (de) 2000-10-18 2003-06-25 Cistem Biotechnologies Gmbh Vakzin-zusammensetzung
AU1412702A (en) 2000-10-27 2002-05-06 Chiron Spa Nucleic acids and proteins from streptococcus groups a and b
AT410798B (de) 2001-01-26 2003-07-25 Cistem Biotechnologies Gmbh Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen
US7482012B2 (en) 2001-02-21 2009-01-27 Id Biomedical Corporation Streptococcus pyogenes polypeptides and corresponding DNA fragments
WO2002077183A2 (en) * 2001-03-21 2002-10-03 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
WO2002083859A2 (en) 2001-04-13 2002-10-24 Wyeth Surface proteins of streptococcus pyogenes
EP2277897A1 (en) * 2001-04-16 2011-01-26 Wyeth Holdings Corporation Streptococcus pneumoniae open reading frames encoding polypeptide antigens and uses thereof
FR2824074A1 (fr) 2001-04-26 2002-10-31 Pasteur Institut Sequence du genome streptococcus agalactiae, application au developpement de vaccins, d'outils de diagnostic, et a l'identification de cibles therapeutiques
EP1450821A1 (en) 2001-12-07 2004-09-01 Intercell AG Immunostimulatory oligodeoxynucleotides
GB0210128D0 (en) 2002-05-02 2002-06-12 Chiron Spa Nucleic acids and proteins from streptococcus groups A & B
PT1648500E (pt) 2003-07-31 2014-10-10 Novartis Vaccines & Diagnostic Composições imunogénicas para estreptococos piogenes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002533123A (ja) * 1998-12-23 2002-10-08 シャイアー・バイオケム・インコーポレイテッド 新規連鎖球菌抗原
WO2002077021A2 (en) * 2001-03-27 2002-10-03 Chiron Srl. Streptococcus pneumoniae proteins and nucleic acids

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011511275A (ja) * 2008-02-01 2011-04-07 サノフィ パストゥール リミテッド 診断的アッセイ
JP2011514167A (ja) * 2008-03-17 2011-05-06 インターセル アーゲー 肺炎連鎖球菌(S.pneumoniae)に対して保護的なペプチドならびにそれに関連する組成物、方法、および使用
JP2012532134A (ja) * 2009-06-29 2012-12-13 ジェノセア バイオサイエンシーズ, インコーポレイテッド StreptococcusPneumoniaeに対するワクチンおよび組成物
KR101748453B1 (ko) * 2009-06-29 2017-06-16 제노시아 바이오사이언스, 인크. 폐렴구균(Streptococcus Pneumoniae)에 대항하는 백신과 조성물
US11207375B2 (en) 2009-06-29 2021-12-28 Genocea Biosciences, Inc. Vaccines and compositions against Streptococcus pneumoniae
JP2013525271A (ja) * 2010-03-12 2013-06-20 チルドレンズ メディカル センター コーポレーション 免疫原およびそのスクリーニング方法
US12036276B2 (en) 2021-09-09 2024-07-16 Affinivax, Inc. Multivalent pneumococcal vaccines
US12377140B2 (en) 2021-09-09 2025-08-05 Affinivax, Inc. Multivalent pneumococcal vaccines

Also Published As

Publication number Publication date
US20100260790A1 (en) 2010-10-14
WO2004092209A2 (en) 2004-10-28
AU2004230244A1 (en) 2004-10-28
JP2012184236A (ja) 2012-09-27
EP2314719A1 (en) 2011-04-27
US20130136761A1 (en) 2013-05-30
JP2011004753A (ja) 2011-01-13
EP2298934A1 (en) 2011-03-23
CN1774447B (zh) 2011-04-06
WO2004092209A3 (en) 2004-12-09
EP2311989A1 (en) 2011-04-20
EP2311988A1 (en) 2011-04-20
CN1774447A (zh) 2006-05-17
EP2333114A1 (en) 2011-06-15
WO2004092209A9 (en) 2008-11-27
EP2336357A1 (en) 2011-06-22
US7635487B2 (en) 2009-12-22
EP2314718A1 (en) 2011-04-27
US20060263846A1 (en) 2006-11-23
EP2311991A1 (en) 2011-04-20
CN102174534A (zh) 2011-09-07
HK1084958A1 (en) 2006-08-11
EP2311987A1 (en) 2011-04-20
CA2522238A1 (en) 2004-10-28
EP1615950A2 (en) 2006-01-18
EP2311990A1 (en) 2011-04-20
AU2004230244B2 (en) 2011-09-22
US8372411B2 (en) 2013-02-12

Similar Documents

Publication Publication Date Title
US8372411B2 (en) S. pneumoniae antigens
CA2413450C (en) Streptococcus antigens
JPH11513371A (ja) 肺炎球菌遺伝子、その一部、それ由来の発現産物、ならびに該遺伝子、該遺伝子の一部分、および該遺伝子産物の使用
JPH09224680A (ja) 肺炎球菌タンパクの構造遺伝子
IL137921A (en) Proteins and polypeptides of group B streptococcus
WO1999053940A1 (en) PNEUMOCOCCAL SURFACE PROTEIN C(PspC), EPITOPIC REGIONS AND STRAIN SELECTION THEREOF, AND USES THEREFOR
US20040052799A1 (en) Nucleic acid and amino acid sequences relating to Helicobacter pylori for diagnostics and therapeutics
AU2004242842B2 (en) Enterococcus antigens
US20100221277A1 (en) Chlamydia pneumoniae antigens
AU2011218655A1 (en) S. Pneumoniae Antigens
HK1084958B (en) S. pneumoniae antigens
Ogunniyi et al. Regulation of pneumococcal surface proteins and capsule
MX2007007886A (es) Vacunas contra neisseria meningitidis.

Legal Events

Date Code Title Description
A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100202

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100506

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100513

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100528

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100604

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100702

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100709

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100802

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20110531

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110929

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20111124

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20120106