CN1774447B - 肺炎链球菌抗原 - Google Patents
肺炎链球菌抗原 Download PDFInfo
- Publication number
- CN1774447B CN1774447B CN200480010200XA CN200480010200A CN1774447B CN 1774447 B CN1774447 B CN 1774447B CN 200480010200X A CN200480010200X A CN 200480010200XA CN 200480010200 A CN200480010200 A CN 200480010200A CN 1774447 B CN1774447 B CN 1774447B
- Authority
- CN
- China
- Prior art keywords
- antibody
- streptococcus pneumoniae
- antigen
- nucleic acid
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03450087.6 | 2003-04-15 | ||
| EP03450087 | 2003-04-15 | ||
| PCT/EP2004/003984 WO2004092209A2 (en) | 2003-04-15 | 2004-04-15 | S. pneumoniae antigens |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011100423445A Division CN102174534A (zh) | 2003-04-15 | 2004-04-15 | 肺炎链球菌抗原 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1774447A CN1774447A (zh) | 2006-05-17 |
| CN1774447B true CN1774447B (zh) | 2011-04-06 |
Family
ID=33186037
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200480010200XA Expired - Fee Related CN1774447B (zh) | 2003-04-15 | 2004-04-15 | 肺炎链球菌抗原 |
| CN2011100423445A Pending CN102174534A (zh) | 2003-04-15 | 2004-04-15 | 肺炎链球菌抗原 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011100423445A Pending CN102174534A (zh) | 2003-04-15 | 2004-04-15 | 肺炎链球菌抗原 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7635487B2 (enExample) |
| EP (11) | EP2311987A1 (enExample) |
| JP (3) | JP2007525157A (enExample) |
| CN (2) | CN1774447B (enExample) |
| AU (1) | AU2004230244B2 (enExample) |
| CA (1) | CA2522238A1 (enExample) |
| WO (1) | WO2004092209A2 (enExample) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6800744B1 (en) * | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US7128918B1 (en) | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| US7262024B2 (en) | 2001-12-20 | 2007-08-28 | Id Biomedical Corporation | Streptococcus antigens |
| AU2004289295B2 (en) * | 2003-11-10 | 2010-08-12 | The Uab Research Foundation | Compositions for reducing bacterial carriage and CNS invasion and methods of using same |
| US20110002962A1 (en) * | 2006-08-17 | 2011-01-06 | The Uab Research Foundation | Immunogenic PcpA Polypeptides and Uses Thereof |
| US8722055B2 (en) | 2006-09-27 | 2014-05-13 | St. Jude Children's Research Hospital | Synthetic Streptococcus pneumoniae vaccine |
| EP1923069A1 (en) * | 2006-11-20 | 2008-05-21 | Intercell AG | Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto |
| CN101688194B (zh) | 2007-05-23 | 2013-09-11 | Uab研究基金会 | 去毒的肺炎球菌神经氨酸酶及其用途 |
| WO2008146164A2 (en) * | 2007-05-25 | 2008-12-04 | Novartis Ag | Streptococcus pneumoniae pilus antigens |
| CA2694466A1 (en) * | 2007-07-23 | 2009-01-29 | Sanofi Pasteur Limited | Immunogenic polypeptides and monoclonal antibodies |
| US20160228500A9 (en) * | 2007-07-23 | 2016-08-11 | Martina Ochs | Immunogenic Polypeptides and Monoclonal Antibodies |
| GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| CN101952728B (zh) * | 2008-02-01 | 2016-05-11 | 圣诺菲·帕斯图尔有限公司 | 用于诊断肺炎链球菌的试验 |
| SI2268618T1 (sl) | 2008-03-03 | 2015-09-30 | Novartis Ag | Spojine in sestavki kot modulatorji aktivnosti TLR |
| AU2009226949A1 (en) * | 2008-03-17 | 2009-09-24 | Intercell Ag | Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto |
| EP2108656A1 (en) * | 2008-03-19 | 2009-10-14 | Beninati, Concetta | Antigenic protein fragments of streptococcus pneumoniae |
| US8348429B2 (en) | 2008-03-27 | 2013-01-08 | Doheny Eye Institute | Optical coherence tomography device, method, and system |
| US11839430B2 (en) | 2008-03-27 | 2023-12-12 | Doheny Eye Institute | Optical coherence tomography-based ophthalmic testing methods, devices and systems |
| WO2009143483A2 (en) * | 2008-05-22 | 2009-11-26 | The Board Of Regents Of The University Of Texas System | PsrP IS A PROTECTIVE ANTIGEN AGAINST PNEUMOCOCCAL INFECTION |
| EP2312994B1 (en) | 2008-07-18 | 2021-01-27 | Doheny Eye Institute | Optical coherence tomography - based ophthalmic testing systems |
| ES2352704B1 (es) * | 2008-08-08 | 2012-06-14 | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)(Titular al 80%) | Secuencia de nucleotido y proteina b-galactosidasa de streptococcus mitis, procedimiento de obtencion y sus aplicaciones. |
| CN102144031B (zh) * | 2008-09-04 | 2013-07-17 | 中国农业科学院生物技术研究所 | 表达发卡rna的dna分子及其构建方法与应用 |
| WO2010029546A2 (en) * | 2008-09-11 | 2010-03-18 | Ben Gurion University Of The Negev Research And Development Authority | Compositions and methods for treating s.pneumoniae infection |
| ATE523204T1 (de) | 2009-02-16 | 2011-09-15 | Karlsruher Inst Technologie | Cd44v6-peptide als bakterielle infektionsinhibitoren |
| EP3017826A1 (en) | 2009-03-24 | 2016-05-11 | Novartis AG | Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates |
| CA2765112A1 (en) | 2009-06-10 | 2010-12-16 | Novartis Ag | Benzonaphthyridine-containing vaccines |
| JP5931724B2 (ja) | 2009-06-29 | 2016-06-08 | ジェノセア バイオサイエンシーズ, インコーポレイテッド | StreptococcusPneumoniaeに対するワクチンおよび組成物 |
| US9950062B2 (en) | 2009-09-02 | 2018-04-24 | Glaxosmithkline Biologicals Sa | Compounds and compositions as TLR activity modulators |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| CN102695523A (zh) | 2009-09-10 | 2012-09-26 | 诺华有限公司 | 针对呼吸道疾病的组合疫苗 |
| WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
| JP5814933B2 (ja) | 2009-12-15 | 2015-11-17 | ノバルティス アーゲー | 免疫増強化合物の均質な懸濁物およびその使用 |
| JP2013525271A (ja) * | 2010-03-12 | 2013-06-20 | チルドレンズ メディカル センター コーポレーション | 免疫原およびそのスクリーニング方法 |
| EA031379B1 (ru) | 2010-03-23 | 2018-12-28 | Новартис Аг | Соединения (липопептиды на основе цистеина) и композиции в качестве агонистов tlr2, применяемые для лечения инфекционных, воспалительных, респираторных и других заболеваний |
| WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
| AU2011336366B2 (en) | 2010-12-03 | 2016-05-12 | Sanofi Pasteur Limited | Composition for immunization against Streptococcus pneumoniae |
| SG10201600435UA (en) * | 2011-01-20 | 2016-02-26 | Genocea Biosciences Inc | Vaccines And Compositions Against Streptococcus Pneumoniae |
| RU2632651C2 (ru) | 2011-05-11 | 2017-10-06 | Чилдрен'С Медикал Сентер Корпорейшн | Модифицированный биотин-связывающий белок, слитые белки на его основе и их применение |
| RU2636350C2 (ru) | 2011-11-07 | 2017-11-22 | Новартис Аг | МОЛЕКУЛА, СОДЕРЖАЩАЯ SPR0096 и SPR2021 |
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| EP2852414B9 (en) | 2012-05-22 | 2020-12-09 | GlaxoSmithKline Biologicals SA | Meningococcus serogroup x conjugate |
| RU2510281C2 (ru) | 2012-06-22 | 2014-03-27 | Общество с ограниченной ответственностью "Эпитоп" (ООО "Эпитоп") | ВАКЦИНА ПРОТИВ ПНЕВМОНИИ, ВЫЗЫВАЕМОЙ Streptococcus pneumoniae, НА ОСНОВЕ ГИБРИДНОГО БЕЛКА |
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| EP4272750A3 (en) | 2013-02-07 | 2024-01-24 | Children's Medical Center, Corp. | Protein antigens that provide protection against pneumococcal colonization and/or disease |
| US12539031B2 (en) | 2013-03-14 | 2026-02-03 | Envision Diagnostics, Inc. | Medical interfaces and other medical devices, systems, and methods for performing eye exams |
| US9226856B2 (en) | 2013-03-14 | 2016-01-05 | Envision Diagnostics, Inc. | Inflatable medical interfaces and other medical devices, systems, and methods |
| US10772497B2 (en) | 2014-09-12 | 2020-09-15 | Envision Diagnostics, Inc. | Medical interfaces and other medical devices, systems, and methods for performing eye exams |
| HK1249149A1 (zh) * | 2015-06-18 | 2018-10-26 | 一般财团法人阪大微生物病研究会 | 肺炎球菌补体依赖性杀菌能力测量方法 |
| EP3834705B1 (en) | 2015-09-17 | 2023-12-20 | Envision Diagnostics, Inc. | Medical interfaces and other medical devices, systems, and methods for performing eye exams |
| WO2017190087A1 (en) | 2016-04-30 | 2017-11-02 | Envision Diagnostics, Inc. | Medical devices, systems, and methods for performing eye exams and eye tracking |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
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| BR112020016314A2 (pt) | 2018-02-12 | 2020-12-15 | Inimmune Corporation | Compostos ou um sais farmaceuticamente aceitáveis, composição farmacêutica, kit, e, métodos para elicitar, intensificar ou modificar uma resposta imunológica, para tratar, prevenir ou reduzir a suscetibilidade a câncer, para tratar, prevenir ou reduzir a suscetibilidade a uma doença infecciosa, para tratar, prevenir ou reduzir a suscetibilidade a uma alergia, para tratar, prevenir ou reduzir a suscetibilidade a uma afecção autoimune, para tratar, prevenir ou reduzir a suscetibilidade em um sujeito à infecção bacteriana, viral, priônica, autoimunidade, câncer ou alergia, para tratar, prevenir ou reduzir a suscetibilidade à autoimunidade, alergia, reperfusão de isquemia ou sepse, para tratar, prevenir ou reduzir a gravidade de ataques epiléticos e para tratar, prevenir ou reduzir a suscetibilidade a doenças oculares como degeneração macular, hipertensão ocular e infecção ocular |
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| CN113164580B (zh) | 2018-09-12 | 2025-06-10 | 儿童医疗中心公司 | 肺炎球菌融合蛋白疫苗 |
| CN112969474A (zh) | 2018-09-12 | 2021-06-15 | 艾芬尼维克斯公司 | 多价肺炎球菌疫苗 |
| RU2701733C1 (ru) * | 2018-12-14 | 2019-10-01 | Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") | Живая вакцина на основе штамма пробиотиков ENTEROCOCCUS FAECIUM L3 для профилактики инфекции, вызванной STREPTOCOCCUS PNEUMONIE |
| CN111748535B (zh) * | 2019-03-28 | 2022-07-05 | 安徽华恒生物科技股份有限公司 | 一种丙氨酸脱氢酶突变体及其在发酵生产l-丙氨酸中的应用 |
| KR20230117105A (ko) | 2020-11-04 | 2023-08-07 | 엘리고 바이오사이언스 | 큐티박테리움 아크네스 재조합 파지, 그의 제조 방법 및 용도 |
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| WO2023236878A1 (zh) * | 2022-06-07 | 2023-12-14 | 北京大学第一医院 | 包含IgA蛋白酶截短体的融合蛋白及其用途 |
| US20240053336A1 (en) * | 2022-08-12 | 2024-02-15 | Arizona Board Of Regents On Behalf Of Arizona State University | Anti-microbial antibody signatures of inflammatory bowel disease and uses thereof |
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2004
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- 2004-04-15 EP EP10178937A patent/EP2333114A1/en not_active Withdrawn
- 2004-04-15 EP EP10178954A patent/EP2311991A1/en not_active Withdrawn
- 2004-04-15 EP EP10178910A patent/EP2336357A1/en not_active Withdrawn
- 2004-04-15 EP EP10178885A patent/EP2311988A1/en not_active Withdrawn
- 2004-04-15 EP EP10178902A patent/EP2298934A1/en not_active Withdrawn
- 2004-04-15 CA CA002522238A patent/CA2522238A1/en not_active Abandoned
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- 2004-04-15 JP JP2006505135A patent/JP2007525157A/ja active Pending
- 2004-04-15 CN CN200480010200XA patent/CN1774447B/zh not_active Expired - Fee Related
- 2004-04-15 CN CN2011100423445A patent/CN102174534A/zh active Pending
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- 2010-08-02 JP JP2010174020A patent/JP2011004753A/ja active Pending
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- 2012-04-25 JP JP2012099977A patent/JP2012184236A/ja active Pending
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2013
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| CN1192241A (zh) * | 1995-06-07 | 1998-09-02 | 生化疫苗公司 | Hsp70家族的链球菌热休克蛋白 |
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| Publication number | Publication date |
|---|---|
| EP2311991A1 (en) | 2011-04-20 |
| HK1084958A1 (en) | 2006-08-11 |
| WO2004092209A2 (en) | 2004-10-28 |
| CA2522238A1 (en) | 2004-10-28 |
| EP2311989A1 (en) | 2011-04-20 |
| EP2336357A1 (en) | 2011-06-22 |
| US8372411B2 (en) | 2013-02-12 |
| US20060263846A1 (en) | 2006-11-23 |
| US7635487B2 (en) | 2009-12-22 |
| EP2333114A1 (en) | 2011-06-15 |
| EP2314719A1 (en) | 2011-04-27 |
| EP1615950A2 (en) | 2006-01-18 |
| EP2311987A1 (en) | 2011-04-20 |
| US20130136761A1 (en) | 2013-05-30 |
| EP2298934A1 (en) | 2011-03-23 |
| CN1774447A (zh) | 2006-05-17 |
| EP2311990A1 (en) | 2011-04-20 |
| JP2012184236A (ja) | 2012-09-27 |
| US20100260790A1 (en) | 2010-10-14 |
| EP2314718A1 (en) | 2011-04-27 |
| CN102174534A (zh) | 2011-09-07 |
| AU2004230244A1 (en) | 2004-10-28 |
| JP2007525157A (ja) | 2007-09-06 |
| EP2311988A1 (en) | 2011-04-20 |
| WO2004092209A3 (en) | 2004-12-09 |
| JP2011004753A (ja) | 2011-01-13 |
| WO2004092209A9 (en) | 2008-11-27 |
| AU2004230244B2 (en) | 2011-09-22 |
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