BRPI0811908A2 - Antígenos de pilus de streptococcus pneumoniae - Google Patents

Antígenos de pilus de streptococcus pneumoniae

Info

Publication number
BRPI0811908A2
BRPI0811908A2 BRPI0811908-2A2A BRPI0811908A BRPI0811908A2 BR PI0811908 A2 BRPI0811908 A2 BR PI0811908A2 BR PI0811908 A BRPI0811908 A BR PI0811908A BR PI0811908 A2 BRPI0811908 A2 BR PI0811908A2
Authority
BR
Brazil
Prior art keywords
streptococcus pneumoniae
polypeptides
methods
pili
inv1
Prior art date
Application number
BRPI0811908-2A2A
Other languages
English (en)
Inventor
Claudio Donati
Vega Masignani
Marirosa Mora
Monica Moshioni
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0811908A2 publication Critical patent/BRPI0811908A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56944—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/315—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Streptococcus (G), e.g. Enterococci
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
BRPI0811908-2A2A 2007-05-25 2008-05-23 Antígenos de pilus de streptococcus pneumoniae BRPI0811908A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94016707P 2007-05-25 2007-05-25
PCT/IB2008/002108 WO2008146164A2 (en) 2007-05-25 2008-05-23 Streptococcus pneumoniae pilus antigens

Publications (1)

Publication Number Publication Date
BRPI0811908A2 true BRPI0811908A2 (pt) 2014-11-18

Family

ID=40075602

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0811908-2A2A BRPI0811908A2 (pt) 2007-05-25 2008-05-23 Antígenos de pilus de streptococcus pneumoniae

Country Status (10)

Country Link
US (1) US20110097360A1 (pt)
EP (1) EP2167531B1 (pt)
CN (1) CN101848929A (pt)
AT (1) ATE550347T1 (pt)
AU (1) AU2008256340A1 (pt)
BR (1) BRPI0811908A2 (pt)
CA (1) CA2688284A1 (pt)
ES (1) ES2381613T3 (pt)
MX (1) MX2009012777A (pt)
WO (1) WO2008146164A2 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101748453B1 (ko) 2009-06-29 2017-06-16 제노시아 바이오사이언스, 인크. 폐렴구균(Ｓｔｒｅｐｔｏｃｏｃｃｕｓ Ｐｎｅｕｍｏｎｉａｅ)에 대항하는 백신과 조성물
CA2790984C (en) * 2010-02-23 2018-07-17 Stichting Katholieke Universiteit Combination vaccine for streptococcus
MX344120B (es) 2011-01-20 2016-12-06 Genocea Biosciences Inc Vacunas y composiciones contra streptococcus pneumoniae.
CN102690319B (zh) * 2011-12-08 2015-05-13 河南科技大学 一种生物被膜状态下猪链球菌总蛋白的提取方法
US9815886B2 (en) 2014-10-28 2017-11-14 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
GB201509782D0 (en) * 2015-06-05 2015-07-22 Isis Innovation Methods and products for fusion protein synthesis
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
EP3630800A4 (en) * 2017-05-31 2021-03-24 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food VACCINE AGAINST NECROTIC ENTERITIS IN POULTRY
CN107164493A (zh) * 2017-06-08 2017-09-15 杭州遂真生物技术有限公司 一种gbs核酸检测试剂盒
CN110407909B (zh) * 2018-11-23 2023-06-02 西南医科大学 一种多肽序列及其自组装材料的制备方法及应用
CN111763261B (zh) * 2019-04-02 2022-08-09 杭州尚健生物技术有限公司 一种融合蛋白及其用途
CN111166749A (zh) * 2020-03-03 2020-05-19 陕西科技大学 血根碱在抑制肺炎链球菌生长中的应用
CN116199751B (zh) * 2023-03-13 2024-03-19 华中农业大学 一种细菌全基因组水平高通量筛选免疫原性抗原蛋白的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8205892D0 (sv) 1982-10-18 1982-10-18 Bror Morein Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
JPS59128338A (ja) * 1982-12-08 1984-07-24 Kitasato Inst:The 歯周炎予防用ワクチン及びその製法
US5173418A (en) * 1985-05-10 1992-12-22 Benzon Pharma, A/S Production in Escherichia coli of extracellular Serratia spp. hydrolases
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
CA2017507C (en) 1989-05-25 1996-11-12 Gary Van Nest Adjuvant formulation comprising a submicron oil droplet emulsion
AUPM873294A0 (en) 1994-10-12 1994-11-03 Csl Limited Saponin preparations and use thereof in iscoms
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
GB9817052D0 (en) 1998-08-05 1998-09-30 Smithkline Beecham Biolog Vaccine
EP2311989A1 (en) * 2003-04-15 2011-04-20 Intercell AG S. pneumoniae antigens

Also Published As

Publication number Publication date
ATE550347T1 (de) 2012-04-15
WO2008146164A2 (en) 2008-12-04
EP2167531A2 (en) 2010-03-31
AU2008256340A1 (en) 2008-12-04
ES2381613T3 (es) 2012-05-29
EP2167531B1 (en) 2012-03-21
WO2008146164A3 (en) 2009-05-28
US20110097360A1 (en) 2011-04-28
CN101848929A (zh) 2010-09-29
CA2688284A1 (en) 2008-12-04
MX2009012777A (es) 2009-12-16

Similar Documents

Publication Publication Date Title
BRPI0811908A2 (pt) Antígenos de pilus de streptococcus pneumoniae
MX2007003402A (es) Composicion inmunogena para su uso en vacunacion contra estafilococos.
MY192183A (en) Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof
PH12015500390B1 (en) Antibodies and vaccines for use in treating ror1 cancers and inhibiting metastasis
NZ760783A (en) Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
EA201070200A1 (ru) Композиции, содержащие пневмококковые антигены
WO2012045001A3 (en) Influenza virus antibodies and immunogens and uses therefor
MX2012003058A (es) Vacunas dirigidas a celulas de langerhans.
AR090294A1 (es) Composiciones de neisseria meningitidis y metodos de las mismas
MXPA05009351A (es) Conjugados de polisacarido-proteina portadora adhesina superficial de estafilococo para inmunizacion contra infecciones nosocomiales.
WO2010113117A3 (en) Preparation of isolated agonist anti-edar monoclonal antibodies
WO2010011999A3 (en) Methods and compositions for eliciting an amyloid-selective immune response
AR093712A1 (es) Composicion inmunogena, vacuna, uso y procedimiento de prevencion o tratamiento
MX2012001495A (es) Polipeptidos de porphyromonas gingivalis.
MX2022000325A (es) Anticuerpos dirigidos contra dll3 y usos de los mismos.
CA2763359C (en) New human rotavirus strains and vaccines
PH12019500377A1 (en) Composition comprising multivalent capsular polysaccharide-transport protein and use thereof
WO2008043000A3 (en) Ehrlicia canis diva (differentiate infected from vaccinated animals)
WO2009115509A3 (en) Antigenic protein fragments of streptococcus pneumoniae
WO2008153772A3 (en) Chlamydia vaccine comprising htra polypeptides
BR112021026364A2 (pt) Antígenos de câncer e métodos
EA201390735A1 (ru) Композиции вакцин с фрагментами расщепленных иммуноглобулинов
NZ599077A (en) Arabinogalactan for enhancing the adaptive immune response
WO2008044149A3 (en) Shigella ipad protein and its use as a vaccine against shigella infection
WO2007113598A3 (en) Peptide mimetope vaccine of- and antibodies against 6b pneumococcal polysaccharides

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]