ATE550347T1 - Streptococcus pneumoniae pilus-antigene - Google Patents
Streptococcus pneumoniae pilus-antigeneInfo
- Publication number
- ATE550347T1 ATE550347T1 AT08789058T AT08789058T ATE550347T1 AT E550347 T1 ATE550347 T1 AT E550347T1 AT 08789058 T AT08789058 T AT 08789058T AT 08789058 T AT08789058 T AT 08789058T AT E550347 T1 ATE550347 T1 AT E550347T1
- Authority
- AT
- Austria
- Prior art keywords
- streptococcus pneumoniae
- polypeptides
- methods
- pili
- inv1
- Prior art date
Links
- 241000193998 Streptococcus pneumoniae Species 0.000 title abstract 10
- 229940031000 streptococcus pneumoniae Drugs 0.000 title abstract 10
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 8
- 238000000034 method Methods 0.000 abstract 4
- 101150110971 CIN7 gene Proteins 0.000 abstract 2
- 101150110298 INV1 gene Proteins 0.000 abstract 2
- 101100397044 Xenopus laevis invs-a gene Proteins 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 229960001438 immunostimulant agent Drugs 0.000 abstract 1
- 239000003022 immunostimulating agent Substances 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56944—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/315—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Streptococcus (G), e.g. Enterococci
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/10—Detection of antigens from microorganism in sample from host
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Analytical Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94016707P | 2007-05-25 | 2007-05-25 | |
| PCT/IB2008/002108 WO2008146164A2 (en) | 2007-05-25 | 2008-05-23 | Streptococcus pneumoniae pilus antigens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE550347T1 true ATE550347T1 (de) | 2012-04-15 |
Family
ID=40075602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08789058T ATE550347T1 (de) | 2007-05-25 | 2008-05-23 | Streptococcus pneumoniae pilus-antigene |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20110097360A1 (de) |
| EP (1) | EP2167531B1 (de) |
| CN (1) | CN101848929A (de) |
| AT (1) | ATE550347T1 (de) |
| AU (1) | AU2008256340A1 (de) |
| BR (1) | BRPI0811908A2 (de) |
| CA (1) | CA2688284A1 (de) |
| ES (1) | ES2381613T3 (de) |
| MX (1) | MX2009012777A (de) |
| WO (1) | WO2008146164A2 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN2012DN00791A (de) | 2009-06-29 | 2015-06-26 | Genocea Biosciences Inc | |
| US9290550B2 (en) | 2010-02-23 | 2016-03-22 | Stitchting Katholieke Universiteit | Combination vaccine for Streptococcus |
| JP6126993B2 (ja) | 2011-01-20 | 2017-05-10 | ジェノセア バイオサイエンシーズ， インコーポレイテッド | 肺炎連鎖球菌（Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ）に対するワクチン及び組成物 |
| CN102690319B (zh) * | 2011-12-08 | 2015-05-13 | 河南科技大学 | 一种生物被膜状态下猪链球菌总蛋白的提取方法 |
| US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| GB201509782D0 (en) * | 2015-06-05 | 2015-07-22 | Isis Innovation | Methods and products for fusion protein synthesis |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| EP3630800A4 (de) * | 2017-05-31 | 2021-03-24 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food | Impfstoff gegen nekrotische enteritis bei geflügel |
| CN107164493A (zh) * | 2017-06-08 | 2017-09-15 | 杭州遂真生物技术有限公司 | 一种gbs核酸检测试剂盒 |
| CN110407909B (zh) * | 2018-11-23 | 2023-06-02 | 西南医科大学 | 一种多肽序列及其自组装材料的制备方法及应用 |
| CN113795306A (zh) * | 2019-03-13 | 2021-12-14 | 圣朱德儿童研究医院 | 用于减少肺炎链球菌传播的疫苗组合物和方法 |
| CN111763261B (zh) * | 2019-04-02 | 2022-08-09 | 杭州尚健生物技术有限公司 | 一种融合蛋白及其用途 |
| CN111166749A (zh) * | 2020-03-03 | 2020-05-19 | 陕西科技大学 | 血根碱在抑制肺炎链球菌生长中的应用 |
| CN116199751B (zh) * | 2023-03-13 | 2024-03-19 | 华中农业大学 | 一种细菌全基因组水平高通量筛选免疫原性抗原蛋白的方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
| JPS59128338A (ja) * | 1982-12-08 | 1984-07-24 | Kitasato Inst:The | 歯周炎予防用ワクチン及びその製法 |
| US5173418A (en) * | 1985-05-10 | 1992-12-22 | Benzon Pharma, A/S | Production in Escherichia coli of extracellular Serratia spp. hydrolases |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| GB9817052D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| EP2311991A1 (de) * | 2003-04-15 | 2011-04-20 | Intercell AG | S. pneumoniae Antigene |
-
2008
- 2008-05-23 AT AT08789058T patent/ATE550347T1/de active
- 2008-05-23 EP EP08789058A patent/EP2167531B1/de not_active Not-in-force
- 2008-05-23 AU AU2008256340A patent/AU2008256340A1/en not_active Abandoned
- 2008-05-23 WO PCT/IB2008/002108 patent/WO2008146164A2/en not_active Ceased
- 2008-05-23 BR BRPI0811908-2A2A patent/BRPI0811908A2/pt not_active Application Discontinuation
- 2008-05-23 ES ES08789058T patent/ES2381613T3/es active Active
- 2008-05-23 CA CA002688284A patent/CA2688284A1/en not_active Abandoned
- 2008-05-23 MX MX2009012777A patent/MX2009012777A/es not_active Application Discontinuation
- 2008-05-23 US US12/451,736 patent/US20110097360A1/en not_active Abandoned
- 2008-05-23 CN CN200880100325A patent/CN101848929A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2009012777A (es) | 2009-12-16 |
| EP2167531A2 (de) | 2010-03-31 |
| WO2008146164A3 (en) | 2009-05-28 |
| BRPI0811908A2 (pt) | 2014-11-18 |
| ES2381613T3 (es) | 2012-05-29 |
| CA2688284A1 (en) | 2008-12-04 |
| AU2008256340A1 (en) | 2008-12-04 |
| US20110097360A1 (en) | 2011-04-28 |
| WO2008146164A2 (en) | 2008-12-04 |
| EP2167531B1 (de) | 2012-03-21 |
| CN101848929A (zh) | 2010-09-29 |
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