MX2009003751A - Proteina ipad de shigella y su uso como vacuna contra infeccion por shigella. - Google Patents

Proteina ipad de shigella y su uso como vacuna contra infeccion por shigella.

Info

Publication number
MX2009003751A
MX2009003751A MX2009003751A MX2009003751A MX2009003751A MX 2009003751 A MX2009003751 A MX 2009003751A MX 2009003751 A MX2009003751 A MX 2009003751A MX 2009003751 A MX2009003751 A MX 2009003751A MX 2009003751 A MX2009003751 A MX 2009003751A
Authority
MX
Mexico
Prior art keywords
shigella
vaccine against
infection
ipad protein
relates
Prior art date
Application number
MX2009003751A
Other languages
English (en)
Inventor
Abdelmounaaim Allaoui
Philippe Sansonetti
Musa Sani
Anne Botteaux
Claude Parsot
Egbert J Boekema
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut filed Critical Pasteur Institut
Publication of MX2009003751A publication Critical patent/MX2009003751A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0283—Shigella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a composiciones y métodos para bloquear la entrada de Shigella en una célula de un animal, para proporcionar protección en contra de, o reducir la severidad de las infecciones Shigella. Más particularmente se refiere al uso de una proteína IpaD obtenida de fuentes naturales y/o a través de síntesis o tecnología recombinante, y conjugados para inducir anticuerpos neutralizantes que tiene actividad protectora en contra de severos estereotipos de Shigella, en particular S. flexeneri. La composición de la invención es útil para prevenir y/o tratar la shigellosa por una bacteria de la familia de Shigella.
MX2009003751A 2006-10-12 2007-10-12 Proteina ipad de shigella y su uso como vacuna contra infeccion por shigella. MX2009003751A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002563214A CA2563214A1 (en) 2006-10-12 2006-10-12 Shigella ipad protein and its use as a potential vaccine against shigella infection
PCT/IB2007/004192 WO2008044149A2 (en) 2006-10-12 2007-10-12 Shigella ipad protein and its use as a vaccine against shigella infection

Publications (1)

Publication Number Publication Date
MX2009003751A true MX2009003751A (es) 2009-11-23

Family

ID=39277150

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009003751A MX2009003751A (es) 2006-10-12 2007-10-12 Proteina ipad de shigella y su uso como vacuna contra infeccion por shigella.

Country Status (9)

Country Link
US (1) US20100196391A1 (es)
EP (1) EP2083853B1 (es)
JP (1) JP5495261B2 (es)
CN (1) CN101707918A (es)
BR (1) BRPI0715551A2 (es)
CA (2) CA2563214A1 (es)
MX (1) MX2009003751A (es)
RU (1) RU2450826C2 (es)
WO (1) WO2008044149A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2526316T3 (es) * 2010-03-23 2015-01-09 Imba-Institut Für Molekulare Biotechnologie Gmbh Procedimientos de identificación de inhibidores del sistema de secreción de tipo III
SG11201501697UA (en) * 2012-09-06 2015-04-29 Eveliqure Biotechnologies Gmbh A novel live attenuated shigella vaccine
US10711252B2 (en) 2015-01-23 2020-07-14 Intralytix, Inc. Shigella bacteriophages and uses thereof
CN115819570B (zh) * 2022-12-16 2023-06-13 华北理工大学 抗志贺氏菌的单克隆抗体及其治疗中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000018355A2 (en) * 1998-09-30 2000-04-06 Walter Reed Army Institute Of Research Use of purified invaplex from gram negative bacteria as a vaccine
ATE420892T1 (de) * 2000-12-14 2009-01-15 Pasteur Institut Sekretierte chlamydia polypeptide und verfahren zur identifizierung davon über ihre sekretion durch gramnegativen bakterientyp iii sekretionsweg
US20030055220A1 (en) * 2001-01-12 2003-03-20 Pierre Legrain Protein-protein interactions between Shigella flexneri polypeptides and mammalian polypeptides
EP1395283B1 (en) * 2001-05-18 2007-03-07 Walter Reed Army Institute of Research Heterologous protection induced by immunization with invaplex vaccine
US20060259534A1 (en) 2003-06-23 2006-11-16 Moritaka Kimura Data distribution method and device
EP1740604A2 (en) * 2004-04-27 2007-01-10 Intercell AG Td antigens

Also Published As

Publication number Publication date
WO2008044149A8 (en) 2009-07-09
CN101707918A (zh) 2010-05-12
RU2450826C2 (ru) 2012-05-20
JP2010505939A (ja) 2010-02-25
CA2563214A1 (en) 2008-04-12
US20100196391A1 (en) 2010-08-05
WO2008044149A2 (en) 2008-04-17
EP2083853B1 (en) 2013-06-12
BRPI0715551A2 (pt) 2013-07-02
WO2008044149A3 (en) 2008-08-07
CA2665943A1 (en) 2008-04-17
EP2083853A2 (en) 2009-08-05
JP5495261B2 (ja) 2014-05-21
RU2009113831A (ru) 2010-11-20

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Legal Events

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HH Correction or change in general
FG Grant or registration