|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
AU1449499A
(en)
|
1997-10-31 |
1999-05-24 |
Maxygen, Incorporated |
Modification of virus tropism and host range by viral genome shuffling
|
|
EP1135468B1
(en)
|
1998-11-10 |
2010-01-06 |
University Of North Carolina At Chapel Hill |
Virus vectors and methods of making and administering the same
|
|
EP1026250A1
(en)
|
1998-12-02 |
2000-08-09 |
Aventis Behring GmbH |
DNA-constructs of blood clotting factors and P-selectin
|
|
EP1010762A1
(en)
|
1998-12-02 |
2000-06-21 |
Aventis Behring Gesellschaft mit beschränkter Haftung |
DNA constructs of blood clotting factors and P-Selectin
|
|
EP1038959A1
(en)
|
1999-03-17 |
2000-09-27 |
Aventis Behring Gesellschaft mit beschränkter Haftung |
Factor VIII without B-domain, comprising one or more insertions of a truncated intron I of factor IX
|
|
EP1048726B1
(en)
|
1999-04-27 |
2006-07-26 |
Négrier, Claude |
Modified factor VIII cDNA
|
|
EP1228234A2
(en)
*
|
2000-03-14 |
2002-08-07 |
Neurologix, Inc. |
Production of chimeric capsid vectors
|
|
US7749492B2
(en)
|
2001-01-05 |
2010-07-06 |
Nationwide Children's Hospital, Inc. |
AAV vectors and methods
|
|
WO2002053703A2
(en)
|
2001-01-05 |
2002-07-11 |
Children's Hospital, Inc. |
Aav2 vectors and methods
|
|
US6723551B2
(en)
|
2001-11-09 |
2004-04-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Production of adeno-associated virus in insect cells
|
|
CN103589692B
(zh)
|
2001-11-13 |
2018-07-24 |
宾夕法尼亚大学托管会 |
检测和/或鉴定腺伴随病毒(aav)序列以及分离所鉴定的新型序列的方法
|
|
DK2359869T3
(en)
|
2001-12-17 |
2019-04-15 |
Univ Pennsylvania |
Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof
|
|
US7858367B2
(en)
|
2002-04-30 |
2010-12-28 |
Duke University |
Viral vectors and methods for producing and using the same
|
|
PL2657248T3
(pl)
|
2003-06-19 |
2017-09-29 |
Genzyme Corporation |
Wiriony AAV o zmniejszonej immunoreaktywności i ich zastosowanie
|
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
EP1668143B1
(en)
|
2003-09-30 |
2013-03-20 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
|
|
US20060166363A1
(en)
|
2004-01-27 |
2006-07-27 |
Sergei Zolotukhin |
Modified baculovirus expression system for production of pseudotyped rAAV vector
|
|
EP1828390B1
(en)
|
2004-12-15 |
2012-06-13 |
The University Of North Carolina At Chapel Hill |
Chimeric vectors
|
|
EP1893754A4
(en)
|
2005-05-31 |
2009-01-21 |
Neurologix Inc |
NEW GLUTAMIC ACID DECARBOXYLASE (GAD) CHIMESES AND USE PROCESSES
|
|
US7867484B2
(en)
|
2006-01-27 |
2011-01-11 |
University Of North Carolina At Chapel Hill |
Heparin and heparan sulfate binding chimeric vectors
|
|
US7588772B2
(en)
|
2006-03-30 |
2009-09-15 |
Board Of Trustees Of The Leland Stamford Junior University |
AAV capsid library and AAV capsid proteins
|
|
WO2008024724A1
(en)
|
2006-08-21 |
2008-02-28 |
Genentech, Inc. |
Aza-benzothiophenyl compounds and methods of use
|
|
US9725485B2
(en)
|
2012-05-15 |
2017-08-08 |
University Of Florida Research Foundation, Inc. |
AAV vectors with high transduction efficiency and uses thereof for gene therapy
|
|
DK2623605T3
(en)
|
2007-04-09 |
2019-03-25 |
Univ Florida |
RAAV VECTOR COMPOSITIONS WITH TYROSIN MODIFIED CAPSIDE PROTEINS AND PROCEDURES FOR USE THEREOF
|
|
EP2158211B1
(en)
*
|
2007-05-31 |
2016-08-10 |
Medigene AG |
Mutated structural protein of a parvovirus
|
|
US8632764B2
(en)
|
2008-04-30 |
2014-01-21 |
University Of North Carolina At Chapel Hill |
Directed evolution and in vivo panning of virus vectors
|
|
EP2396343B1
(en)
|
2009-02-11 |
2017-05-17 |
The University of North Carolina At Chapel Hill |
Modified virus vectors and methods of making and using the same
|
|
CA2754335C
(en)
|
2009-03-04 |
2019-12-24 |
Medigene Ag |
Assembly activating protein (aap) and its use for the manufacture of parvovirus particles essentially consisting of vp3
|
|
GB0911870D0
(en)
|
2009-07-08 |
2009-08-19 |
Ucl Business Plc |
Optimised coding sequence and promoter
|
|
EP3795581A3
(en)
|
2011-08-24 |
2021-06-09 |
The Board of Trustees of the Leland Stanford Junior University |
New avv capsid proteins for nucleic acid transfer
|
|
EP2771455B1
(en)
|
2011-10-28 |
2016-10-05 |
The University of North Carolina At Chapel Hill |
Cell line for production of adeno-associated virus
|
|
PL2900686T3
(pl)
|
2012-09-28 |
2021-01-25 |
The University Of North Carolina At Chapel Hill |
Wektory aav ukierunkowane na oligodendrocyty
|
|
DK2911687T3
(da)
|
2012-10-26 |
2019-05-13 |
Univ Brussel Vrije |
Vektor til levermålrettet genterapi af hæmofili og fremgangsmåder og anvendelse deraf
|
|
WO2014159546A1
(en)
|
2013-03-14 |
2014-10-02 |
Asklepios Biopharmaceutical, Inc. |
Modified soluble vegf receptor-1 genes and vectors for gene therapy
|
|
ES2926774T3
(es)
|
2013-03-15 |
2022-10-28 |
Univ North Carolina Chapel Hill |
Métodos y composiciones para vectores AAV de doble unión de glicano
|
|
KR102298579B1
(ko)
|
2013-05-21 |
2021-09-07 |
유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 |
캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도
|
|
NZ716102A
(en)
|
2013-07-22 |
2021-12-24 |
The Children’S Hospital Of Philadelphia |
Variant aav and compositions, methods and uses for gene transfer to cells, organs and tissues
|
|
RS63942B1
(sr)
|
2013-08-27 |
2023-02-28 |
Res Inst Nationwide Childrens Hospital |
Proizvodi i postupci za lečenje amiotrofične lateralne skleroze
|
|
HUE052676T2
(hu)
*
|
2013-10-11 |
2021-05-28 |
Massachusetts Eye & Ear Infirmary |
Eljárások õsi vírusszekvenciák elõrejelzésére és alkalmazásaik
|
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
WO2015126972A1
(en)
|
2014-02-21 |
2015-08-27 |
University Of Florida Research Foundation, Inc. |
Methods and compositions for gene delivery to on bipolar cells
|
|
EP3113787B1
(en)
|
2014-03-04 |
2019-12-04 |
University of Florida Research Foundation, Inc. |
Improved raav vectors and methods for transduction of photoreceptors and rpe cells
|
|
ES2744565T3
(es)
|
2014-04-25 |
2020-02-25 |
Genethon |
Tratamiento de la hiperbilirrubinemia
|
|
LT3137497T
(lt)
|
2014-05-02 |
2021-07-26 |
Genzyme Corporation |
Aav vektoriai, skirti tinklainės ir cns genų terapijai
|
|
US10577627B2
(en)
|
2014-06-09 |
2020-03-03 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
WO2016065001A1
(en)
|
2014-10-21 |
2016-04-28 |
University Of Massachusetts |
Recombinant aav variants and uses thereof
|
|
GB201420139D0
(en)
|
2014-11-12 |
2014-12-24 |
Ucl Business Plc |
Factor IX gene therapy
|
|
AU2015349759B2
(en)
|
2014-11-21 |
2022-01-06 |
The University Of North Carolina At Chapel Hill |
Aav vectors targeted to the central nervous system
|
|
GB201502137D0
(en)
|
2015-02-09 |
2015-03-25 |
Ucl Business Plc |
Treatment
|
|
US10648000B2
(en)
|
2015-02-16 |
2020-05-12 |
University Of Florida Research Foundation, Incorporated |
rAAV vector compositions, methods for targeting vascular endothelial cells and use in treatment of type I diabetes
|
|
US20180245073A1
(en)
|
2015-02-23 |
2018-08-30 |
Voyager Therapeutics, Inc. |
Regulatable expression using adeno-associated virus (aav)
|
|
FI3265178T3
(fi)
|
2015-03-02 |
2026-08-03 |
Adverum Biotechnologies Inc |
Koostumuksia ja menetelmiä polynukleotidien viemiseksi intravitreaalisesti retinaalisiin tappisoluihin
|
|
JP6836999B2
(ja)
|
2015-03-24 |
2021-03-03 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ |
アデノ随伴ウイルス変異体及びその使用方法
|
|
US10081659B2
(en)
|
2015-04-06 |
2018-09-25 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
Adeno-associated vectors for enhanced transduction and reduced immunogenicity
|
|
EP3285788B1
(en)
|
2015-04-23 |
2024-12-18 |
University of Massachusetts |
Modulation of aav vector transgene expression
|
|
GB201508026D0
(en)
*
|
2015-05-11 |
2015-06-24 |
Ucl Business Plc |
Capsid
|
|
EP4378487A3
(en)
|
2015-06-23 |
2024-09-04 |
The Children's Hospital of Philadelphia |
Modified factor ix, and compositions, methods and uses for gene transfer to cells, organs and tissues
|
|
WO2017015102A1
(en)
|
2015-07-17 |
2017-01-26 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for achieving high levels of transduction in human liver cells
|
|
WO2017023724A1
(en)
|
2015-07-31 |
2017-02-09 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of aadc deficiency
|
|
IL314171A
(en)
|
2015-09-28 |
2024-09-01 |
Univ Florida |
Methods and compositions for antibody-evading virus vectors
|
|
WO2017066764A2
(en)
|
2015-10-16 |
2017-04-20 |
William Marsh Rice University |
Modification of n-terminal region of capsid proteins for enhanced properties of adeno-associated viruses
|
|
US20180230489A1
(en)
|
2015-10-28 |
2018-08-16 |
Voyager Therapeutics, Inc. |
Regulatable expression using adeno-associated virus (aav)
|
|
AU2016343979A1
(en)
|
2015-10-29 |
2018-05-10 |
Voyager Therapeutics, Inc. |
Delivery of central nervous system targeting polynucleotides
|
|
PE20231949A1
(es)
|
2015-10-30 |
2023-12-05 |
Spark Therapeutics Inc |
VARIANTES DEL FACTOR VIII REDUCIDO CON CpG, COMPOSICIONES Y METODOS Y USOS PARA EL TRATAMIENTO DE TRASTORNOS DE LA HEMOSTASIA
|
|
SG10201912763QA
(en)
|
2015-11-05 |
2020-02-27 |
Bamboo Therapeutics Inc |
Modified friedreich ataxia genes and vectors for gene therapy
|
|
US10406244B2
(en)
|
2015-12-02 |
2019-09-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
AAV vectors with expanded packaging capacity
|
|
WO2017096164A1
(en)
|
2015-12-02 |
2017-06-08 |
The Board Of Trustees Of The Leland Stanford Junior University |
Novel recombinant adeno-associated virus capsids with enhanced human skeletal muscle tropism
|
|
AU2016366549B2
(en)
|
2015-12-11 |
2022-11-10 |
California Institute Of Technology |
Targeting peptides for directing adeno-associated viruses (AAVs)
|
|
US11124546B2
(en)
|
2015-12-14 |
2021-09-21 |
The University Of North Carolina At Chapel Hill |
Modified capsid proteins for enhanced delivery of parvovirus vectors
|
|
CA3014637A1
(en)
|
2016-02-16 |
2017-08-24 |
Mark A. Kay |
Novel recombinant adeno-associated virus capsids resistant to pre-existing human neutralizing antibodies
|
|
AU2017234929B2
(en)
|
2016-03-18 |
2024-05-02 |
The Children's Hospital Of Philadelphia |
Therapeutic for treatment of diseases including the central nervous system
|
|
US11433116B2
(en)
|
2016-04-14 |
2022-09-06 |
Cedars-Sinai Medical Center |
GJA1 isoforms protect against metabolic stress
|
|
EP3448874A4
(en)
|
2016-04-29 |
2020-04-22 |
Voyager Therapeutics, Inc. |
COMPOSITIONS FOR TREATING A DISEASE
|
|
WO2017189963A1
(en)
|
2016-04-29 |
2017-11-02 |
Voyager Therapeutics, Inc. |
Compositions for the treatment of disease
|
|
US10584337B2
(en)
|
2016-05-18 |
2020-03-10 |
Voyager Therapeutics, Inc. |
Modulatory polynucleotides
|
|
ES3066293T3
(en)
|
2016-06-16 |
2026-05-12 |
Charite Univ Berlin Koerperschaft Des Oeffentlichen Rechts |
Neuropeptide-expressing vectors and methods for the treatment of epilepsy
|
|
JP6994018B2
(ja)
|
2016-07-26 |
2022-01-14 |
バイオマリン ファーマシューティカル インコーポレイテッド |
新規アデノ随伴ウイルスキャプシドタンパク質
|
|
HUE053747T2
(hu)
|
2016-08-15 |
2021-07-28 |
Genzyme Corp |
Eljárások AAV kimutatására
|
|
WO2018045347A1
(en)
|
2016-09-02 |
2018-03-08 |
Spark Therapeutics, Inc. |
Methods and vectors for treating cns disorders
|
|
EP3293259A1
(en)
|
2016-09-12 |
2018-03-14 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
KR102617502B1
(ko)
|
2016-09-12 |
2023-12-26 |
제네똥 |
산-알파 글루코시다제 변이체 및 이의 용도
|
|
EP3293203A1
(en)
|
2016-09-12 |
2018-03-14 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
KR20190075964A
(ko)
|
2016-10-13 |
2019-07-01 |
유니버시티 오브 매사추세츠 |
Aav 캡시드 설계
|
|
EP3532075A4
(en)
|
2016-10-27 |
2020-07-08 |
Intima Bioscience, Inc. |
VIRAL METHODS OF MANUFACTURING GENETICALLY MODIFIED CELLS
|
|
EP3583220A4
(en)
|
2017-02-15 |
2021-07-07 |
The University of North Carolina at Chapel Hill |
PROCEDURES AND COMPOSITIONS FOR GENERAL TRANSFER IN THE VASCULAR SYSTEM
|
|
MA47820A
(fr)
|
2017-03-10 |
2020-01-15 |
Genethon |
Traitement de la glycogénose de type iii
|
|
WO2018170310A1
(en)
|
2017-03-15 |
2018-09-20 |
The University Of North Carolina At Chapel Hill |
Polyploid adeno-associated virus vectors and methods of making and using the same
|
|
EP4219806A3
(en)
|
2017-04-11 |
2023-09-27 |
Ruprecht-Karls-Universität Heidelberg |
Adeno-associated virus library
|
|
WO2018200419A1
(en)
|
2017-04-23 |
2018-11-01 |
The Trustees Of The University Of Pennsylvania |
Viral vectors comprising engineered aav capsids and compositions containing the same
|
|
EP3618839A4
(en)
|
2017-05-05 |
2021-06-09 |
Voyager Therapeutics, Inc. |
COMPOSITIONS AND METHODS OF TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
|
|
MX2019013172A
(es)
|
2017-05-05 |
2020-09-07 |
Voyager Therapeutics Inc |
Composiciones y metodos para tratar la enfermedad de huntington.
|
|
WO2018226887A1
(en)
|
2017-06-07 |
2018-12-13 |
Spark Therapeutics, Inc. |
ENHANCING AGENTS FOR IMPROVED CELL TRANSFECTION AND/OR rAAV VECTOR PRODUCTION
|
|
JOP20190269A1
(ar)
|
2017-06-15 |
2019-11-20 |
Voyager Therapeutics Inc |
بولي نوكليوتيدات aadc لعلاج مرض باركنسون
|
|
EP3658250A4
(en)
|
2017-06-30 |
2021-10-27 |
Spark Therapeutics, Inc. |
AAV VECTOR COLUMN CLEANING PROCEDURE
|
|
CA3071769A1
(en)
|
2017-07-31 |
2019-02-07 |
Reflection Biotechnologies Limited |
Cellular models of and therapies for ocular diseases
|
|
US20200237930A1
(en)
|
2017-08-01 |
2020-07-30 |
Spark Therapeutics, Inc. |
Factor viii (fviii) gene therapy methods
|
|
US11512327B2
(en)
|
2017-08-03 |
2022-11-29 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of AAV
|
|
JP7329254B2
(ja)
|
2017-08-29 |
2023-08-18 |
ルプレヒト－カールス－ウニヴェルジテート ハイデルベルク |
キメラ抗原受容体（ｃａｒ）－ｔ細胞療法の調節のための合理的に設計されたウイルス様粒子
|
|
US20200377887A1
(en)
|
2017-09-22 |
2020-12-03 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating huntington's disease
|
|
US12123027B2
(en)
|
2017-10-12 |
2024-10-22 |
Ascend Advanced Therapies Limited |
Life-cycle-defective adenovirus helper viruses, their production and use for producing rAAV
|