WO2003035836A2 - Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends - Google Patents

Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends Download PDF

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Publication number
WO2003035836A2
WO2003035836A2 PCT/US2002/033756 US0233756W WO03035836A2 WO 2003035836 A2 WO2003035836 A2 WO 2003035836A2 US 0233756 W US0233756 W US 0233756W WO 03035836 A2 WO03035836 A2 WO 03035836A2
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WO
WIPO (PCT)
Prior art keywords
immunomer
linker
deoxy
nucleoside
immunostimulatory
Prior art date
Application number
PCT/US2002/033756
Other languages
French (fr)
Inventor
Sudhir Agrawal
Ekambar R. Kandimalla
Dong Yu
Lakshmi Bhagat
Original Assignee
Hybridon Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US34476701P priority Critical
Priority to US60/344,767 priority
Application filed by Hybridon Inc. filed Critical Hybridon Inc.
Publication of WO2003035836A2 publication Critical patent/WO2003035836A2/en

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