RU2432357C2 - ПОЛИПЕПТИДЫ НЕТИПИРУЕМОЙ Haemophilus influenzae - Google Patents
ПОЛИПЕПТИДЫ НЕТИПИРУЕМОЙ Haemophilus influenzae Download PDFInfo
- Publication number
- RU2432357C2 RU2432357C2 RU2006144093/10A RU2006144093A RU2432357C2 RU 2432357 C2 RU2432357 C2 RU 2432357C2 RU 2006144093/10 A RU2006144093/10 A RU 2006144093/10A RU 2006144093 A RU2006144093 A RU 2006144093A RU 2432357 C2 RU2432357 C2 RU 2432357C2
- Authority
- RU
- Russia
- Prior art keywords
- polypeptide
- antibody
- medicine
- influenzae
- polypeptides
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0410866.8 | 2004-05-14 | ||
| GBGB0410866.8A GB0410866D0 (en) | 2004-05-14 | 2004-05-14 | Haemophilius influenzae |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2006144093A RU2006144093A (ru) | 2008-06-20 |
| RU2432357C2 true RU2432357C2 (ru) | 2011-10-27 |
Family
ID=32527109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006144093/10A RU2432357C2 (ru) | 2004-05-14 | 2005-05-16 | ПОЛИПЕПТИДЫ НЕТИПИРУЕМОЙ Haemophilus influenzae |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US7749518B2 (enExample) |
| EP (5) | EP2341069A1 (enExample) |
| JP (2) | JP2008506364A (enExample) |
| CN (1) | CN1997663A (enExample) |
| BR (1) | BRPI0511118A (enExample) |
| CA (1) | CA2566632A1 (enExample) |
| GB (1) | GB0410866D0 (enExample) |
| IN (1) | IN2015KN00290A (enExample) |
| RU (1) | RU2432357C2 (enExample) |
| WO (1) | WO2005111066A2 (enExample) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4763210B2 (ja) * | 2000-02-28 | 2011-08-31 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | ナイセリアのタンパク質の異種発現 |
| MXPA05003863A (es) * | 2002-10-11 | 2005-09-08 | Chiron Srl | Vacunas polipeptidicas para amplia proteccion contra lineas hipervirulentas de meningococos. |
| WO2006138527A2 (en) * | 2005-06-16 | 2006-12-28 | Children's Hospital, Inc. | Genes of an otitis media isolate of nontypeable haemophilus influenzae |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| BRPI0609460A2 (pt) * | 2005-03-30 | 2010-04-13 | Novartis Vaccines & Diagnostics Inc | haemophilus influenzae tipo b |
| KR20080042865A (ko) | 2005-08-10 | 2008-05-15 | 아르네 포르스그렌 아베 | 모락셀라 카타랄리스와 상피세포, 세포외기질 단백질 및보체계의 상호작용 |
| UA92782C2 (ru) * | 2006-01-17 | 2010-12-10 | Арне Форсгрен | Новый поверхностный белок haemophilus influenzae (белок е; ре) |
| US9132183B2 (en) * | 2007-03-09 | 2015-09-15 | Newport Laboratories | Modified live (JMSO strain) Haemophilus parasuis vaccine |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| CA2747340A1 (en) * | 2008-12-17 | 2010-06-24 | Novartis Ag | Meningococcal vaccines including hemoglobin receptor |
| WO2010092176A2 (en) * | 2009-02-13 | 2010-08-19 | Intercell Ag | Nontypable haemophilus influenzae antigens |
| ITMI20090946A1 (it) | 2009-05-28 | 2010-11-29 | Novartis Ag | Espressione di proteine ricombinanti |
| PL3243526T3 (pl) | 2010-07-06 | 2020-05-18 | Glaxosmithkline Biologicals S.A. | Dostarczanie rna w celu wyzwolenia wielu szlaków immunologicznych |
| ES2557382T3 (es) | 2010-07-06 | 2016-01-25 | Glaxosmithkline Biologicals Sa | Liposomas con lípidos que tienen un valor de pKa ventajoso para el suministro de ARN |
| US9770463B2 (en) | 2010-07-06 | 2017-09-26 | Glaxosmithkline Biologicals Sa | Delivery of RNA to different cell types |
| PL2591114T3 (pl) | 2010-07-06 | 2017-08-31 | Glaxosmithkline Biologicals Sa | Immunizacja dużych ssaków małymi dawkami rna |
| FI4005592T3 (fi) | 2010-07-06 | 2023-01-13 | Virionin kaltaisia kuljetuspartikkeleita itsereplikoituville rna-molekyyleille | |
| HUE061068T2 (hu) | 2010-08-31 | 2023-05-28 | Glaxosmithkline Biologicals Sa | Pegilált liposzómák immunogént kódoló RNS szállítására |
| EP3542789A3 (en) | 2010-08-31 | 2020-01-01 | GlaxoSmithKline Biologicals SA | Lipids suitable for liposomal delivery of protein-coding rna |
| EP4098324A1 (en) | 2010-10-11 | 2022-12-07 | GlaxoSmithKline Biologicals S.A. | Antigen delivery platforms |
| TW201302779A (zh) | 2011-04-13 | 2013-01-16 | Glaxosmithkline Biolog Sa | 融合蛋白質及組合疫苗 |
| JP2014516028A (ja) * | 2011-05-11 | 2014-07-07 | リースベック ヘルスケア スウェーデン アクティエボラーグ | ラミニン及びビトロネクチン結合特性を有するタンパク質f−新規インフルエンザ菌付着因子 |
| EP4115875A1 (en) | 2011-07-06 | 2023-01-11 | GlaxoSmithKline Biologicals S.A. | Liposomes having useful n:p ratio for delivery of rna molecules |
| CA2840989A1 (en) | 2011-07-06 | 2013-01-10 | Novartis Ag | Immunogenic combination compositions and uses thereof |
| EP2750707B1 (en) | 2011-08-31 | 2018-10-24 | GlaxoSmithKline Biologicals SA | Pegylated liposomes for delivery of immunogen-encoding rna |
| US10279026B2 (en) * | 2012-04-26 | 2019-05-07 | Glaxosmithkline Biologicals Sa | Antigens and antigen combinations |
| MX374919B (es) * | 2012-04-26 | 2025-03-06 | Glaxosmithkline Biologicals S A Star | ANTÍGENOS Y COMBINACIONES DE ANTÍGENOS PARA USARSE PARA ELEVAR LA RESPUESTA INMUNE CONTRA Haemophilus influenzae. |
| CA2882382A1 (en) | 2012-09-18 | 2014-03-27 | Novartis Ag | Outer membrane vesicles |
| WO2014136086A1 (en) | 2013-03-08 | 2014-09-12 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
| US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| EP3083556B1 (en) | 2013-12-19 | 2019-12-25 | Novartis AG | Lipids and lipid compositions for the delivery of active agents |
| US10426737B2 (en) | 2013-12-19 | 2019-10-01 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| US10342761B2 (en) | 2014-07-16 | 2019-07-09 | Novartis Ag | Method of encapsulating a nucleic acid in a lipid nanoparticle host |
| US10502027B2 (en) * | 2014-08-27 | 2019-12-10 | Switchfloat Holdings Limited | Oil field tubular and an internal sleeve for use therewith, and a method of deactivating a float valve within the oil field tubular |
| US10125092B2 (en) | 2014-09-05 | 2018-11-13 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| EP3061826A1 (en) | 2015-02-27 | 2016-08-31 | Novartis AG | Flavivirus replicons |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| WO2016200787A2 (en) * | 2015-06-09 | 2016-12-15 | The Board Of Regents Of The University Of Oklahoma | Compositions and treatments for haemophilus influenzae |
| US20180207067A1 (en) | 2015-07-14 | 2018-07-26 | Research Institute at Nationwide Children's Hospit al | Novel formulation for the elimination of cariogenic and opportunistic pathogens within the oral cavity |
| EP3328429B1 (en) | 2015-07-31 | 2025-07-16 | The Research Institute at Nationwide Children's Hospital | Peptides and antibodies for the removal of biofilms |
| WO2017066719A2 (en) | 2015-10-14 | 2017-04-20 | Research Institute At Nationwide Children's Hospital | Hu specific interfering agents |
| WO2017185250A1 (zh) * | 2016-04-27 | 2017-11-02 | 拜西欧斯(北京)生物技术有限公司 | 兴奋性神经毒性相关损伤的治疗方法 |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| AU2018206560B9 (en) * | 2017-01-04 | 2025-04-03 | Research Institute At Nationwide Children's Hospital | Antibody fragments for the treatment of biofilm-related disorders |
| WO2018129078A1 (en) | 2017-01-04 | 2018-07-12 | Research Institute At Nationwide Children's Hospital | Dnabii vaccines and antibodies with enhanced activity |
| US20180221468A1 (en) * | 2017-01-19 | 2018-08-09 | Iowa State University Research Foundation, Inc. | Haemophilus influenzae immunogen |
| EP3595445B1 (en) | 2017-03-15 | 2024-09-04 | The Research Institute at Nationwide Children's Hospital | Composition and methods for disruption of bacterial biofilms without accompanying inflammation |
| WO2020072993A1 (en) | 2018-10-05 | 2020-04-09 | Research Institute At Nationwide Children's Hospital | Hmgb1 protein derivatives for the removal of biofilms cross-reference to related application |
| US20220143168A1 (en) * | 2019-02-27 | 2022-05-12 | Evaxion Biotech A/S | Vaccines targeting H. influenzae |
| KR20220032066A (ko) | 2019-07-08 | 2022-03-15 | 더 리서치 인스티튜트 앳 네이션와이드 칠드런스 하스피탈 | 생물막을 파괴하기 위한 항체 조성물 |
| US12378586B2 (en) | 2020-02-28 | 2025-08-05 | Trait Biosciences, Inc. | Systems, methods, and compositions for the glycosylation of cannabinoid compounds |
| US12116614B2 (en) | 2020-06-30 | 2024-10-15 | Research Institute At Nationwide Children's Hospital | Methods for determining antibiotic sensitivity |
| WO2022081750A1 (en) | 2020-10-14 | 2022-04-21 | George Mason Research Foundation, Inc. | Ionizable lipids and methods of manufacture and use thereof |
| CN115678869B (zh) * | 2021-07-28 | 2025-08-29 | 梅花(上海)生物科技有限公司 | 一株重组菌株及其生产氨基酸的方法 |
| WO2023021427A1 (en) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Freeze-drying of lipid nanoparticles (lnps) encapsulating rna and formulations thereof |
| WO2023021421A1 (en) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Low-dose lyophilized rna vaccines and methods for preparing and using the same |
| CN114574456B (zh) * | 2022-03-18 | 2022-08-12 | 华南理工大学 | 一种亚硝酸盐还原酶突变体及其编码基因和应用 |
| GB202303019D0 (en) | 2023-03-01 | 2023-04-12 | Glaxosmithkline Biologicals Sa | Method of lyophilisation |
| CN116236575B (zh) * | 2023-03-07 | 2025-03-25 | 北京化工大学 | 一种光控偶联型纳米探针及其制备方法、光控偶联的纳米颗粒组合物与应用 |
| GB202311382D0 (en) | 2023-07-25 | 2023-09-06 | Glaxosmithkline Biologicals Sa | Lyophilised compostion |
| CN118388664B (zh) * | 2024-05-21 | 2024-12-03 | 广东省农业科学院动物卫生研究所 | 副猪嗜血杆菌融合抗原及其应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2194757C2 (ru) * | 1993-11-08 | 2002-12-20 | Коннот Лабораториз Лимитед | ФРАГМЕНТ ДНК, КОДИРУЮЩИЙ ФРАГМЕНТ БЕЛКА РЕЦЕПТОРА ТРАНСФЕРРИНА ШТАММА Haemophilus (ВАРИАНТЫ), ПЛАЗМИДНЫЙ ВЕКТОР (ВАРИАНТЫ), РЕКОМБИНАНТНЫЙ БЕЛОК (ВАРИАНТЫ), ВЫДЕЛЕННЫЙ И ОЧИЩЕННЫЙ БЕЛОК (ВАРИАНТЫ), ИММУНОГЕННАЯ КОМПОЗИЦИЯ И СПОСОБ ПОЛУЧЕНИЯ ВЫДЕЛЕННОГО И ОЧИЩЕННОГО БЕЛКА |
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2004
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- 2005-05-16 RU RU2006144093/10A patent/RU2432357C2/ru not_active IP Right Cessation
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- 2005-05-16 CN CNA2005800238288A patent/CN1997663A/zh active Pending
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- 2005-05-16 IN IN290KON2015 patent/IN2015KN00290A/en unknown
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2194757C2 (ru) * | 1993-11-08 | 2002-12-20 | Коннот Лабораториз Лимитед | ФРАГМЕНТ ДНК, КОДИРУЮЩИЙ ФРАГМЕНТ БЕЛКА РЕЦЕПТОРА ТРАНСФЕРРИНА ШТАММА Haemophilus (ВАРИАНТЫ), ПЛАЗМИДНЫЙ ВЕКТОР (ВАРИАНТЫ), РЕКОМБИНАНТНЫЙ БЕЛОК (ВАРИАНТЫ), ВЫДЕЛЕННЫЙ И ОЧИЩЕННЫЙ БЕЛОК (ВАРИАНТЫ), ИММУНОГЕННАЯ КОМПОЗИЦИЯ И СПОСОБ ПОЛУЧЕНИЯ ВЫДЕЛЕННОГО И ОЧИЩЕННОГО БЕЛКА |
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| RU2006144093A (ru) | 2008-06-20 |
| EP1745067A2 (en) | 2007-01-24 |
| US20100303822A1 (en) | 2010-12-02 |
| JP2008506364A (ja) | 2008-03-06 |
| BRPI0511118A (pt) | 2007-11-27 |
| CN1997663A (zh) | 2007-07-11 |
| US20080267966A1 (en) | 2008-10-30 |
| US8124098B2 (en) | 2012-02-28 |
| US20140234363A1 (en) | 2014-08-21 |
| US9102729B2 (en) | 2015-08-11 |
| WO2005111066A2 (en) | 2005-11-24 |
| EP2343313A1 (en) | 2011-07-13 |
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| US20120148615A1 (en) | 2012-06-14 |
| EP2351774A1 (en) | 2011-08-03 |
| WO2005111066A3 (en) | 2006-05-26 |
| JP2012000112A (ja) | 2012-01-05 |
| EP2351773A1 (en) | 2011-08-03 |
| WO2005111066A8 (en) | 2007-05-18 |
| US7749518B2 (en) | 2010-07-06 |
| GB0410866D0 (en) | 2004-06-16 |
| EP2341069A1 (en) | 2011-07-06 |
| IN2015KN00290A (enExample) | 2015-06-12 |
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