|
WO1981002911A1
(en)
|
1980-04-07 |
1981-10-15 |
J Berman |
Window shade roller assembly
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
ATE114473T1
(de)
*
|
1984-04-30 |
1994-12-15 |
Procter & Gamble |
Ausrüstung für die verwendung bei der behandlung von osteoporose.
|
|
JPS61134325A
(ja)
|
1984-12-04 |
1986-06-21 |
Teijin Ltd |
ハイブリツド抗体遺伝子の発現方法
|
|
US4631211A
(en)
*
|
1985-03-25 |
1986-12-23 |
Scripps Clinic & Research Foundation |
Means for sequential solid phase organic synthesis and methods using the same
|
|
US5618920A
(en)
*
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US5225539A
(en)
*
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US5266683A
(en)
|
1988-04-08 |
1993-11-30 |
Stryker Corporation |
Osteogenic proteins
|
|
US5344654A
(en)
*
|
1988-04-08 |
1994-09-06 |
Stryker Corporation |
Prosthetic devices having enhanced osteogenic properties
|
|
US5324819A
(en)
|
1988-04-08 |
1994-06-28 |
Stryker Corporation |
Osteogenic proteins
|
|
US5010175A
(en)
|
1988-05-02 |
1991-04-23 |
The Regents Of The University Of California |
General method for producing and selecting peptides with specific properties
|
|
US5298852A
(en)
*
|
1988-12-22 |
1994-03-29 |
Robert Bosch Gmbh |
Arrangement for and method of controlling a three-phase-generator in a vehicle
|
|
US5530101A
(en)
*
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5561173A
(en)
*
|
1990-06-19 |
1996-10-01 |
Carolyn M. Dry |
Self-repairing, reinforced matrix materials
|
|
KR100240308B1
(ko)
|
1991-03-06 |
2000-01-15 |
플레믹 크리스티안 |
인간화된단클론성항체및혼성단클론성항체
|
|
US5656593A
(en)
|
1991-03-11 |
1997-08-12 |
Creative Biomolecules, Inc. |
Morphogen induced periodontal tissue regeneration
|
|
US5118667A
(en)
*
|
1991-05-03 |
1992-06-02 |
Celtrix Pharmaceuticals, Inc. |
Bone growth factors and inhibitors of bone resorption for promoting bone formation
|
|
CA2078539C
(en)
|
1991-09-18 |
2005-08-02 |
Kenya Shitara |
Process for producing humanized chimera antibody
|
|
ES2136092T3
(es)
*
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
DE69233022T2
(de)
|
1991-11-04 |
2004-02-12 |
Genetics Institute, LLC, Cambridge |
Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
|
|
GB9125979D0
(en)
|
1991-12-06 |
1992-02-05 |
Wellcome Found |
Antibody
|
|
NZ249677A
(en)
|
1992-02-19 |
1996-08-27 |
Schering Corp |
Monoclonal antibodies and compositions useful for treating il-4 diseases and intermediates for making such antibodies
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US5639641A
(en)
*
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
IT1255522B
(it)
|
1992-09-24 |
1995-11-09 |
Ubaldo Conte |
Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
|
|
CA2151486A1
(en)
*
|
1993-01-12 |
1994-07-21 |
Arthur J. Ammann |
Tgf-beta formulation for inducing bone growth
|
|
TW303299B
(enExample)
*
|
1993-07-22 |
1997-04-21 |
Lilly Co Eli |
|
|
US5705154A
(en)
|
1995-03-08 |
1998-01-06 |
Schering Corporation |
Humanized monoclonal antibodies against human interleukin-4
|
|
US5550134A
(en)
*
|
1995-05-10 |
1996-08-27 |
Eli Lilly And Company |
Methods for inhibiting bone loss
|
|
DE19647853A1
(de)
*
|
1996-11-19 |
1998-05-20 |
Bioph Biotech Entw Pharm Gmbh |
Verbindungen mit verbesserter knorpel- und/oder knocheninduzierender Aktivität
|
|
US5939039A
(en)
|
1997-01-16 |
1999-08-17 |
Orthovita, Inc. |
Methods for production of calcium phosphate
|
|
JP4388602B2
(ja)
*
|
1997-02-07 |
2009-12-24 |
ストライカー コーポレイション |
マトリクスを含まない骨形成デバイス、移植片、およびその使用方法
|
|
US20020098222A1
(en)
*
|
1997-03-13 |
2002-07-25 |
John F. Wironen |
Bone paste
|
|
US7041641B2
(en)
*
|
1997-03-20 |
2006-05-09 |
Stryker Corporation |
Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
|
|
DE69818456T2
(de)
*
|
1997-04-22 |
2004-07-29 |
Washington Research Foundation, Seattle |
Knochentransplantate und -prothesen beschichtet mit tartratbeständiger säurephosphatase
|
|
US6025538A
(en)
|
1998-11-20 |
2000-02-15 |
Musculoskeletal Transplant Foundation |
Compound bone structure fabricated from allograft tissue
|
|
DE69942782D1
(de)
|
1998-11-27 |
2010-10-28 |
Ucb Sa |
Zusammensetzungen und Verfahren zur Erhöhung der Knochenmineralisierung
|
|
US20040009535A1
(en)
|
1998-11-27 |
2004-01-15 |
Celltech R&D, Inc. |
Compositions and methods for increasing bone mineralization
|
|
US6756480B2
(en)
*
|
2000-04-27 |
2004-06-29 |
Amgen Inc. |
Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
|
|
US20030082233A1
(en)
*
|
2000-12-01 |
2003-05-01 |
Lyons Karen M. |
Method and composition for modulating bone growth
|
|
WO2002067978A1
(en)
*
|
2001-02-23 |
2002-09-06 |
Wyeth |
Chondrogenic potential of human bone marrow-derived cd105+ cells by bmp
|
|
US6949251B2
(en)
*
|
2001-03-02 |
2005-09-27 |
Stryker Corporation |
Porous β-tricalcium phosphate granules for regeneration of bone tissue
|
|
BR0209564A
(pt)
|
2001-05-11 |
2004-10-26 |
Wyeth Corp |
Animal transgênico, embrião, camundongo transgênico, modelo animal para o estudo da modulação da densidade óssea, célula isolada, ácido nucleico para marcar o gene pela recombinação homóloga, e, métodos para estudar determinantes da massa óssea, para estudar moduladores de massa óssea, para estudar a massa óssea, para estudar um efeito hbm sobre os distúrbios ósseos, para identificar marcadores substitutos da formação/reabsorção ósseas, para estudar efeitos de hbm sobre os distúrbios cardìacos, para avaliar tratamentos cárdio-protetores quanto aos efeitos de modulação da massa óssea, para modular a densidade óssea, para produzir um camundongo transgênico e para identificar genes associados com a massa óssea
|
|
TWI267378B
(en)
*
|
2001-06-08 |
2006-12-01 |
Wyeth Corp |
Calcium phosphate delivery vehicles for osteoinductive proteins
|
|
MY143582A
(en)
*
|
2001-06-26 |
2011-05-31 |
Amgent Fremont Inc |
Antibodies to opgl
|
|
CN100515504C
(zh)
|
2001-10-12 |
2009-07-22 |
美国英佛曼公司 |
涂层,涂布体及其制造方法
|
|
EP1446114A4
(en)
*
|
2001-11-08 |
2005-05-25 |
Merck & Co Inc |
COMPOSITIONS AND METHODS FOR TREATING OSTEOPOROSIS
|
|
JP2005525312A
(ja)
*
|
2002-01-10 |
2005-08-25 |
オステオトロフィン エルエルシー |
骨同化物質を用いた骨疾患の治療方法
|
|
JP2005519067A
(ja)
*
|
2002-01-17 |
2005-06-30 |
ザ ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム |
トロンビンペプチド誘導体を用いた骨成長および軟骨形成の刺激
|
|
JP3646167B2
(ja)
*
|
2002-02-19 |
2005-05-11 |
独立行政法人産業技術総合研究所 |
フォスフォフォリンを含む複合生体材料
|
|
US7332276B2
(en)
*
|
2002-03-01 |
2008-02-19 |
Celltech R&D, Inc. |
Methods to increase or decrease bone density
|
|
US7166133B2
(en)
*
|
2002-06-13 |
2007-01-23 |
Kensey Nash Corporation |
Devices and methods for treating defects in the tissue of a living being
|
|
WO2003106657A2
(en)
|
2002-06-14 |
2003-12-24 |
Stowers Institute For Medical Research |
Wise/sost nucleic acid sequences and amino acid sequences
|
|
US7585501B2
(en)
|
2002-06-14 |
2009-09-08 |
Stowers Institute For Medical Research |
Compositions and methods for treating kidney disease
|
|
US7893218B2
(en)
|
2003-06-16 |
2011-02-22 |
Stowers Institute For Medical Research |
Antibodies that specifically bind SOST peptides
|
|
US20040002770A1
(en)
|
2002-06-28 |
2004-01-01 |
King Richard S. |
Polymer-bioceramic composite for orthopaedic applications and method of manufacture thereof
|
|
US20060246060A1
(en)
*
|
2002-07-02 |
2006-11-02 |
Nesta Douglas P |
Novel stable formulation
|
|
US20040023322A1
(en)
*
|
2002-08-01 |
2004-02-05 |
Goodheart Clyde R. |
Method of producing non-recombinant BMP-2 and use thereof
|
|
KR20040023356A
(ko)
|
2002-09-11 |
2004-03-18 |
현대모비스 주식회사 |
파킹브레이크 작동시 출발제한 시스템 및 그 방법
|
|
US7374776B2
(en)
|
2002-09-30 |
2008-05-20 |
Regen Biotech, Inc. |
Bone-filling composition for stimulating bone-forming and bone-consolidation comprising calcium sulfate and viscous biopolymers
|
|
JP3851602B2
(ja)
*
|
2002-10-02 |
2006-11-29 |
ペンタックス株式会社 |
骨形成治療デバイス
|
|
JP2007525953A
(ja)
|
2003-06-06 |
2007-09-13 |
ワイス |
骨リモデリングを調節する物質を同定するための方法および材料、ならびにそれによって同定された物質
|
|
EP1636270B1
(en)
|
2003-06-16 |
2016-07-20 |
UCB Pharma S.A. |
Antibodies specific for sclerostin and methods for increasing bone mineralization
|
|
US7943393B2
(en)
|
2003-07-14 |
2011-05-17 |
Phynexus, Inc. |
Method and device for extracting an analyte
|
|
US6976816B2
(en)
|
2003-08-01 |
2005-12-20 |
Dana Corporation |
Combination lock washer and spindle bearing assembly
|
|
MY141763A
(en)
*
|
2003-09-18 |
2010-06-30 |
Novartis Ag |
Pharmaceutical products comprising bisphosphonates
|
|
US8461155B2
(en)
*
|
2003-09-22 |
2013-06-11 |
University Of Connecticut |
Sclerostin and the inhibition of WNT signaling and bone formation
|
|
US8895540B2
(en)
*
|
2003-11-26 |
2014-11-25 |
DePuy Synthes Products, LLC |
Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
|
|
WO2005070439A1
(en)
*
|
2004-01-09 |
2005-08-04 |
Regeneration Technologies Inc. |
Implant comprising a human muscle tissue matrix
|
|
US7189263B2
(en)
|
2004-02-03 |
2007-03-13 |
Vita Special Purpose Corporation |
Biocompatible bone graft material
|
|
US7531518B2
(en)
*
|
2004-05-14 |
2009-05-12 |
Unigene Laboratories Inc. |
Method for fostering bone formation and preservation
|
|
US7648965B2
(en)
*
|
2004-05-14 |
2010-01-19 |
Unigene Laboratories Inc. |
Method for fostering bone formation and preservation
|
|
WO2005118636A2
(en)
*
|
2004-05-27 |
2005-12-15 |
Acceleron Pharma Inc. |
Tgf derepressors and uses related thereto
|
|
MX2007001221A
(es)
|
2004-08-04 |
2007-03-23 |
Amgen Inc |
Anticuerpos para proteina dickkopf-1 (dkk-1).
|
|
US8337873B2
(en)
*
|
2004-10-22 |
2012-12-25 |
The Board Of Trustees Of The University Of Illinois |
Hollow and porous orthopaedic or dental implant that delivers a biological agent
|
|
ES2902872T3
(es)
*
|
2005-01-06 |
2022-03-30 |
Kuros Biosurgery Ag |
Matrices suplementadas para la reparación de fracturas óseas
|
|
US7531533B2
(en)
*
|
2005-01-27 |
2009-05-12 |
Asahi Kasei Pharma Corporation |
6-Membered heterocyclic compound and use thereof
|
|
US8071574B2
(en)
|
2005-02-22 |
2011-12-06 |
John Dennis Bobyn |
Implant improving local bone formation
|
|
US20060198863A1
(en)
|
2005-03-03 |
2006-09-07 |
Musculoskeletal Transplant Foundation |
Ceramic composition for filling bone defects
|
|
US8003108B2
(en)
*
|
2005-05-03 |
2011-08-23 |
Amgen Inc. |
Sclerostin epitopes
|
|
US7592429B2
(en)
*
|
2005-05-03 |
2009-09-22 |
Ucb Sa |
Sclerostin-binding antibody
|
|
JP2006320442A
(ja)
|
2005-05-18 |
2006-11-30 |
Toshiba Ceramics Co Ltd |
リン酸カルシウム系骨補填材
|
|
US20060293667A1
(en)
*
|
2005-05-19 |
2006-12-28 |
Agnes Vignery |
Bone implant device and methods of using same
|
|
WO2006135734A2
(en)
|
2005-06-10 |
2006-12-21 |
The Regents Of The University Of California |
Compositions and methods for altering bone density and bone patterning
|
|
CN101287761A
(zh)
*
|
2005-06-15 |
2008-10-15 |
先灵公司 |
抗-igf1r抗体制剂
|
|
WO2007030616A2
(en)
|
2005-09-09 |
2007-03-15 |
Wright Medical Technology, Inc. |
Composite bone graft substitute cement and articles produced therefrom
|
|
KR20080084808A
(ko)
|
2005-11-17 |
2008-09-19 |
바이오미메틱 세라퓨틱스, 인크. |
ｒｈＰＤＧＦ-ＢＢ 및 생체적합성 매트릭스를 사용하는상악안면골 보강
|
|
US8158828B2
(en)
*
|
2005-11-28 |
2012-04-17 |
Gtx, Inc. |
Nuclear receptor binding agents
|
|
CN101378782A
(zh)
*
|
2005-12-21 |
2009-03-04 |
惠氏公司 |
粘度降低的蛋白质制剂及其用途
|
|
WO2008133722A2
(en)
|
2006-11-10 |
2008-11-06 |
Ucb Pharma S.A. |
Anti human sclerostin antibodies
|
|
US8178099B2
(en)
|
2006-12-29 |
2012-05-15 |
Osteogenex Inc. |
Methods of altering bone growth by administration of sost or wise antagonist or agonist
|
|
MY149129A
(en)
|
2007-03-20 |
2013-07-15 |
Lilly Co Eli |
Anti-sclerostin antibodies
|
|
CN101663043B
(zh)
|
2007-04-27 |
2014-03-12 |
尤尼基因实验室公司 |
促进和保持骨生长的方法和组合物
|
|
CL2008002775A1
(es)
|
2007-09-17 |
2008-11-07 |
Amgen Inc |
Uso de un agente de unión a esclerostina para inhibir la resorción ósea.
|
|
TWI489993B
(zh)
*
|
2007-10-12 |
2015-07-01 |
Novartis Ag |
骨硬化素（ｓｃｌｅｒｏｓｔｉｎ）抗體組合物及使用方法
|
|
JP6013915B2
(ja)
*
|
2010-11-17 |
2016-10-25 |
中外製薬株式会社 |
血液凝固第ｖｉｉｉ因子の機能を代替する機能を有する多重特異性抗原結合分子
|
|
US8790651B2
(en)
*
|
2011-07-21 |
2014-07-29 |
Zoetis Llc |
Interleukin-31 monoclonal antibody
|
|
JP6511233B2
(ja)
|
2014-08-28 |
2019-05-15 |
株式会社竹中工務店 |
柱脚部と鉄骨梁との接合構造
|