MX2014001374A - Composicion farmaceutica para el tratamiento y/o prevencion de cancer. - Google Patents

Composicion farmaceutica para el tratamiento y/o prevencion de cancer.

Info

Publication number
MX2014001374A
MX2014001374A MX2014001374A MX2014001374A MX2014001374A MX 2014001374 A MX2014001374 A MX 2014001374A MX 2014001374 A MX2014001374 A MX 2014001374A MX 2014001374 A MX2014001374 A MX 2014001374A MX 2014001374 A MX2014001374 A MX 2014001374A
Authority
MX
Mexico
Prior art keywords
antibody
cancer treatment
drug composition
protein
prevention
Prior art date
Application number
MX2014001374A
Other languages
English (en)
Other versions
MX348581B (es
Inventor
Fumiyoshi Okano
Shinichi Kobayashi
Takanori Saito
Yoshitaka Minamida
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of MX2014001374A publication Critical patent/MX2014001374A/es
Publication of MX348581B publication Critical patent/MX348581B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Abstract

La presente invención identifica una proteína de antígeno de cáncer que se expresa específicamente en la superficie de las células cancerosas, y proporciona un anticuerpo que tiene la proteína como un objetivo y una aplicación del anticuerpo como un agente para el tratamiento y/o prevención del cáncer. La presente invención se refiere a: un anticuerpo o un fragmento del mismo que contiene una región variable de la cadena pesada que contiene los números de secuencia 5, 6, y 7, y una región variable de la cadena ligera que contiene los números de secuencia 9, 10 y 11, y que tiene reactividad inmunológica con la proteína CAPRIN-1, y una composición farmacéutica para el tratamiento y/o la prevención del cáncer que contiene el anticuerpo o fragmento como un ingrediente activo.
MX2014001374A 2011-08-04 2012-08-03 Composicion farmaceutica para el tratamiento y/o prevencion de cancer. MX348581B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011171303 2011-08-04
PCT/JP2012/069819 WO2013018883A1 (ja) 2011-08-04 2012-08-03 癌の治療及び／又は予防用医薬組成物

Publications (2)

Publication Number Publication Date
MX2014001374A true MX2014001374A (es) 2014-03-21
MX348581B MX348581B (es) 2017-06-20

Family

ID=47629397

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014001374A MX348581B (es) 2011-08-04 2012-08-03 Composicion farmaceutica para el tratamiento y/o prevencion de cancer.

Country Status (16)

Country Link
US (1) US9180188B2 (es)
EP (1) EP2740798B1 (es)
JP (1) JP6065592B2 (es)
KR (1) KR101968499B1 (es)
CN (1) CN103717737B (es)
AU (1) AU2012290946B2 (es)
BR (1) BR112014002614B1 (es)
CA (1) CA2844030C (es)
DK (1) DK2740798T3 (es)
ES (1) ES2618026T3 (es)
HU (1) HUE033183T2 (es)
MX (1) MX348581B (es)
PL (1) PL2740798T3 (es)
PT (1) PT2740798T (es)
RU (1) RU2595400C2 (es)
WO (1) WO2013018883A1 (es)

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CN103717737B (zh) 2015-06-10
PT2740798T (pt) 2017-03-13
JP6065592B2 (ja) 2017-01-25
KR20140054182A (ko) 2014-05-08
EP2740798B1 (en) 2016-12-07
CA2844030A1 (en) 2013-02-07
BR112014002614B1 (pt) 2022-09-20
BR112014002614A2 (pt) 2018-02-20
US20140193434A1 (en) 2014-07-10
RU2014108049A (ru) 2015-09-10
AU2012290946B2 (en) 2016-04-21
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EP2740798A4 (en) 2015-04-15
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