BR112012018951A8 - anticorpo monoclonal, composição farmacêutica, combinação farmacêutica, uso de um anticorpo, uso de uma composição farmacêutica e uso de uma combinação farmacêutica - Google Patents
anticorpo monoclonal, composição farmacêutica, combinação farmacêutica, uso de um anticorpo, uso de uma composição farmacêutica e uso de uma combinação farmacêutica Download PDFInfo
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- BR112012018951A8 BR112012018951A8 BR112012018951A BR112012018951A BR112012018951A8 BR 112012018951 A8 BR112012018951 A8 BR 112012018951A8 BR 112012018951 A BR112012018951 A BR 112012018951A BR 112012018951 A BR112012018951 A BR 112012018951A BR 112012018951 A8 BR112012018951 A8 BR 112012018951A8
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
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- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
composição farmacêutica, anticorpo, combinação farmacêutica e método para o tratamento e/ou prevenção de um câncer de acordo com a presente invenção, foi identificada uma proteína antígeno do câncer que é especificamente expressa sobre as superfícies de células cancerosas e, portanto, é fornecido o uso de um anticorpo direcionado contra a proteína antígeno do câncer como um agente para o tratamento e/ou prevenção de um câncer. especificamente, a presente invenção fornece uma composição farmacêutica para o tratamento e/ou prevenção de um câncer, que compreende um anticorpo ou fragmento do mesmo como um ingrediente ativo possuindo reatividade imunológica com um polipeptídeo parcial da proteína caprin-1, em que a caprin-1 é representada por qualquer uma das sequências pares numeradas de seq id nos: 2 a 30, e em que o polipeptídeo compreende a sequência de aminoácidos representada pela seq id no: 37 ou uma sequência de aminoácidos possuindo 80% ou mais de identidade de sequência com a sequência de aminoácidos.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010023453 | 2010-02-04 | ||
| JP2010-023453 | 2010-02-04 | ||
| JP2010-183116 | 2010-08-08 | ||
| JP2010183161 | 2010-08-18 | ||
| PCT/JP2011/052412 WO2011096533A1 (ja) | 2010-02-04 | 2011-02-04 | 癌の治療及び／又は予防用医薬組成物 |
Publications (5)
| Publication Number | Publication Date |
|---|---|
| BR112012018951A2 BR112012018951A2 (pt) | 2017-06-27 |
| BR112012018951A8 true BR112012018951A8 (pt) | 2020-03-31 |
| BR112012018951B1 BR112012018951B1 (pt) | 2020-05-12 |
| BR112012018951B8 BR112012018951B8 (pt) | 2020-06-09 |
| BR112012018951C8 BR112012018951C8 (pt) | 2020-06-23 |
Family
ID=44355527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012018951A BR112012018951C8 (pt) | 2010-02-04 | 2011-02-04 | anticorpo monoclonal, composição farmacêutica, combinação farmacêutica, uso de um anticorpo, uso de uma composição farmacêutica e uso de uma combinação farmacêutica |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8937160B2 (pt) |
| EP (1) | EP2532366B1 (pt) |
| JP (1) | JP5742713B2 (pt) |
| KR (1) | KR101801667B1 (pt) |
| CN (1) | CN102821789B (pt) |
| AU (1) | AU2011211698B2 (pt) |
| BR (1) | BR112012018951C8 (pt) |
| CA (1) | CA2788716C (pt) |
| DK (1) | DK2532366T3 (pt) |
| ES (1) | ES2606173T3 (pt) |
| HU (1) | HUE030742T2 (pt) |
| MX (1) | MX342291B (pt) |
| PL (1) | PL2532366T3 (pt) |
| PT (1) | PT2532366T (pt) |
| RU (1) | RU2597971C2 (pt) |
| WO (1) | WO2011096533A1 (pt) |
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| RU2598258C2 (ru) | 2010-02-04 | 2016-09-20 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики рака |
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| WO2011096528A1 (ja) * | 2010-02-04 | 2011-08-11 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| KR101805520B1 (ko) | 2010-02-04 | 2017-12-07 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방용 의약 조성물 |
| AU2011211700B2 (en) | 2010-02-04 | 2015-06-11 | Toray Industries, Inc. | Medicament for treating and/or preventing cancer |
| DK2532366T3 (da) | 2010-02-04 | 2017-01-02 | Toray Industries | Farmaceutisk sammensætning til behandling og/eller forebyggelse af cancer |
| PL2532680T3 (pl) | 2010-02-04 | 2015-10-30 | Toray Industries | Kompozycja medyczna do leczenia raka i/lub zapobiegania |
| US9796775B2 (en) | 2011-08-04 | 2017-10-24 | Toray Industries, Inc. | Method for detecting pancreatic cancer |
| PL3351630T3 (pl) | 2011-08-04 | 2020-05-18 | Toray Industries, Inc. | Kompozycja farmaceutyczna zawierająca przeciwciała przeciwko CAPRIN-1 do leczenia nowotworu i/lub zapobiegania nowotworowi |
| PL2740489T3 (pl) | 2011-08-04 | 2017-06-30 | Toray Industries, Inc. | Kompozycja farmaceutyczna do leczenia i/lub zapobiegania raka trzustki |
-
2011
- 2011-02-04 DK DK11739881.8T patent/DK2532366T3/da active
- 2011-02-04 JP JP2011510202A patent/JP5742713B2/ja active Active
- 2011-02-04 PL PL11739881T patent/PL2532366T3/pl unknown
- 2011-02-04 RU RU2012137504/10A patent/RU2597971C2/ru active
- 2011-02-04 CN CN201180017395.0A patent/CN102821789B/zh active Active
- 2011-02-04 WO PCT/JP2011/052412 patent/WO2011096533A1/ja active Application Filing
- 2011-02-04 ES ES11739881.8T patent/ES2606173T3/es active Active
- 2011-02-04 HU HUE11739881A patent/HUE030742T2/en unknown
- 2011-02-04 EP EP11739881.8A patent/EP2532366B1/en active Active
- 2011-02-04 MX MX2012009000A patent/MX342291B/es active IP Right Grant
- 2011-02-04 CA CA2788716A patent/CA2788716C/en active Active
- 2011-02-04 US US13/577,212 patent/US8937160B2/en active Active
- 2011-02-04 BR BR112012018951A patent/BR112012018951C8/pt active IP Right Grant
- 2011-02-04 KR KR1020127022752A patent/KR101801667B1/ko active IP Right Grant
- 2011-02-04 AU AU2011211698A patent/AU2011211698B2/en active Active
- 2011-02-04 PT PT117398818T patent/PT2532366T/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2011096533A1 (ja) | 2013-06-13 |
| US8937160B2 (en) | 2015-01-20 |
| RU2597971C2 (ru) | 2016-09-20 |
| BR112012018951C8 (pt) | 2020-06-23 |
| PL2532366T3 (pl) | 2017-02-28 |
| MX2012009000A (es) | 2012-08-31 |
| EP2532366B1 (en) | 2016-09-07 |
| BR112012018951A2 (pt) | 2017-06-27 |
| CN102821789A (zh) | 2012-12-12 |
| ES2606173T3 (es) | 2017-03-23 |
| CA2788716A1 (en) | 2011-08-11 |
| WO2011096533A1 (ja) | 2011-08-11 |
| EP2532366A4 (en) | 2013-12-04 |
| PT2532366T (pt) | 2016-12-20 |
| CN102821789B (zh) | 2016-03-02 |
| CA2788716C (en) | 2019-06-18 |
| AU2011211698A1 (en) | 2012-08-23 |
| JP5742713B2 (ja) | 2015-07-01 |
| DK2532366T3 (da) | 2017-01-02 |
| BR112012018951B1 (pt) | 2020-05-12 |
| RU2012137504A (ru) | 2014-03-10 |
| MX342291B (es) | 2016-09-23 |
| BR112012018951B8 (pt) | 2020-06-09 |
| KR20130033347A (ko) | 2013-04-03 |
| EP2532366A1 (en) | 2012-12-12 |
| HUE030742T2 (en) | 2017-06-28 |
| KR101801667B1 (ko) | 2017-11-27 |
| US20130045210A1 (en) | 2013-02-21 |
| AU2011211698B2 (en) | 2015-07-16 |
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