BR112014027991A2 - agentes para neutralização de influenza - Google Patents

agentes para neutralização de influenza

Info

Publication number
BR112014027991A2
BR112014027991A2 BR112014027991A BR112014027991A BR112014027991A2 BR 112014027991 A2 BR112014027991 A2 BR 112014027991A2 BR 112014027991 A BR112014027991 A BR 112014027991A BR 112014027991 A BR112014027991 A BR 112014027991A BR 112014027991 A2 BR112014027991 A2 BR 112014027991A2
Authority
BR
Brazil
Prior art keywords
agents
antibodies
influenza
neutralizing influenza
neutralizing
Prior art date
Application number
BR112014027991A
Other languages
English (en)
Inventor
Tharakaraman Kannan
Sasisekharan Ram
Raguram S
Sound-Ararajan Venkataramanan
Subramanian Vidya
Sasisekharan Viswanathan
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of BR112014027991A2 publication Critical patent/BR112014027991A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

resumo patente de invenção: "agentes para neutralização de influenza". a presente invenção refere-se a anticorpos (por exemplo, anticorpos monoclonais, anticorpos de humano, anticorpos humanizados, etc.), que se ligam a múltiplas cepas de influenza. tais anticorpos são úteis, por exemplo, em profilaxia, tratamento, diagnóstico e/ou estudo de influenza.
BR112014027991A 2012-05-10 2013-03-14 agentes para neutralização de influenza BR112014027991A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261645453P 2012-05-10 2012-05-10
PCT/US2013/031704 WO2013169377A1 (en) 2012-05-10 2013-03-14 Agents for influenza neutralization

Publications (1)

Publication Number Publication Date
BR112014027991A2 true BR112014027991A2 (pt) 2017-07-18

Family

ID=49548780

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014027991A BR112014027991A2 (pt) 2012-05-10 2013-03-14 agentes para neutralização de influenza

Country Status (14)

Country Link
US (4) US9683030B2 (pt)
EP (2) EP3492101A3 (pt)
JP (2) JP6431477B2 (pt)
KR (1) KR102122618B1 (pt)
CN (2) CN104507500A (pt)
AU (2) AU2013260123A1 (pt)
BR (1) BR112014027991A2 (pt)
CA (1) CA2871160C (pt)
CL (1) CL2014003052A1 (pt)
HK (1) HK1207970A1 (pt)
IL (1) IL235237A0 (pt)
MX (1) MX2014013678A (pt)
SG (2) SG10201807059QA (pt)
WO (1) WO2013169377A1 (pt)

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EP3492101A3 (en) 2012-05-10 2019-10-23 Massachusetts Institute Of Technology Agents for influenza neutralization
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MY186585A (en) 2015-02-05 2021-07-28 Janssen Vaccines & Prevention Bv Binding molecules directed against influenza hemagglutinin and uses thereof
JP6921002B2 (ja) * 2015-05-11 2021-08-18 ヤンセン ファッシンズ アンド プリベンション ベーフェーＪａｎｓｓｅｎ Ｖａｃｃｉｎｅｓ ＆ Ｐｒｅｖｅｎｔｉｏｎ Ｂ．Ｖ． ペプチド模倣化合物を中和するインフルエンザウイルス
WO2017083627A1 (en) 2015-11-13 2017-05-18 Visterra, Inc. Compositions and methods for treating and preventing influenza
CN109195629A (zh) 2016-02-24 2019-01-11 威特拉公司 流行性感冒抗体分子制剂
KR101887876B1 (ko) 2016-08-18 2018-08-13 한국과학기술연구원 H5형 조류독감 바이러스에 특이적으로 결합하는 핵산 압타머 및 이를 이용하는 h5형 조류독감 바이러스의 검출방법
CN113924147A (zh) 2019-03-25 2022-01-11 威特拉公司 用于治疗和预防流感的组合物和方法
EP4073107A1 (en) 2019-12-11 2022-10-19 Visterra, Inc. Compositions and methods for treating and preventing influenza

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Also Published As

Publication number Publication date
IL235237A0 (en) 2014-12-31
US9982037B2 (en) 2018-05-29
WO2013169377A1 (en) 2013-11-14
CL2014003052A1 (es) 2015-06-26
KR102122618B1 (ko) 2020-06-29
JP6431477B2 (ja) 2018-12-05
AU2013260123A1 (en) 2014-11-13
CN104507500A (zh) 2015-04-08
EP2846833A1 (en) 2015-03-18
EP2846833A4 (en) 2016-01-06
SG10201807059QA (en) 2018-09-27
EP3492101A3 (en) 2019-10-23
US20130302348A1 (en) 2013-11-14
MX2014013678A (es) 2015-02-04
US10538578B2 (en) 2020-01-21
US20200123234A1 (en) 2020-04-23
KR20150008180A (ko) 2015-01-21
AU2018202468B2 (en) 2020-04-16
EP3492101A2 (en) 2019-06-05
US20170306003A1 (en) 2017-10-26
HK1207970A1 (en) 2016-02-19
US9683030B2 (en) 2017-06-20
US20190062407A1 (en) 2019-02-28
CA2871160A1 (en) 2013-11-14
CA2871160C (en) 2023-03-14
JP2015517492A (ja) 2015-06-22
JP2018118991A (ja) 2018-08-02
SG11201406769RA (en) 2014-11-27
CN109265541A (zh) 2019-01-25
AU2018202468A1 (en) 2018-04-26
US10947300B2 (en) 2021-03-16

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
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B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements