MX342291B - Composicion farmaceutica para el tratamiento y/o prevencion del cancer. - Google Patents

Composicion farmaceutica para el tratamiento y/o prevencion del cancer.

Info

Publication number
MX342291B
MX342291B MX2012009000A MX2012009000A MX342291B MX 342291 B MX342291 B MX 342291B MX 2012009000 A MX2012009000 A MX 2012009000A MX 2012009000 A MX2012009000 A MX 2012009000A MX 342291 B MX342291 B MX 342291B
Authority
MX
Mexico
Prior art keywords
cancer
antibody
amino acid
prevention
acid sequence
Prior art date
Application number
MX2012009000A
Other languages
English (en)
Other versions
MX2012009000A (es
Inventor
Kobayashi Shinichi
Okano Fumiyoshi
Saito Takanori
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of MX2012009000A publication Critical patent/MX2012009000A/es
Publication of MX342291B publication Critical patent/MX342291B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a una proteína de antígeno de cáncer que se expresa específicamente en las superficies de células de cáncer y de esta manera se proporciona el uso de un anticuerpo que dirige la proteína de antígeno de cáncer como un agente para tratar y/o prevenir el cáncer. Específicamente, la invención actual proporciona una composición farmacéutica para tratar y/o prevenir un cáncer, que comprende un anticuerpo o un fragmento del mismo como un ingrediente activo que tiene reactividad inmunológica con un péptido parcial de CAPRIN-1, que se representa por cualquiera de las secuencias de numeración uniforme de SEQ ID NOS: 2 hasta 30, en donde el polipéptido tiene la secuencia de aminoácidos representada por SEQ ID NO: 37 o una secuencia de aminoácidos que tiene 80% o más de identidad de secuencia con la secuencia de aminoácidos.
MX2012009000A 2010-02-04 2011-02-04 Composicion farmaceutica para el tratamiento y/o prevencion del cancer. MX342291B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2010023453 2010-02-04
JP2010183161 2010-08-18
PCT/JP2011/052412 WO2011096533A1 (ja) 2010-02-04 2011-02-04 癌の治療及び／又は予防用医薬組成物

Publications (2)

Publication Number Publication Date
MX2012009000A MX2012009000A (es) 2012-08-31
MX342291B true MX342291B (es) 2016-09-23

Family

ID=44355527

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012009000A MX342291B (es) 2010-02-04 2011-02-04 Composicion farmaceutica para el tratamiento y/o prevencion del cancer.

Country Status (16)

Country Link
US (1) US8937160B2 (es)
EP (1) EP2532366B1 (es)
JP (1) JP5742713B2 (es)
KR (1) KR101801667B1 (es)
CN (1) CN102821789B (es)
AU (1) AU2011211698B2 (es)
BR (1) BR112012018951C8 (es)
CA (1) CA2788716C (es)
DK (1) DK2532366T3 (es)
ES (1) ES2606173T3 (es)
HU (1) HUE030742T2 (es)
MX (1) MX342291B (es)
PL (1) PL2532366T3 (es)
PT (1) PT2532366T (es)
RU (1) RU2597971C2 (es)
WO (1) WO2011096533A1 (es)

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PL2532364T3 (pl) 2010-02-04 2016-11-30 Kompozycja farmaceutyczna zawierająca przeciwciała anty CAPRIN-1 do leczenia i/lub zapobiegania nowotworowi
KR101805520B1 (ko) 2010-02-04 2017-12-07 도레이 카부시키가이샤 암의 치료 및/또는 예방용 의약 조성물
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PL2532364T3 (pl) 2010-02-04 2016-11-30 Kompozycja farmaceutyczna zawierająca przeciwciała anty CAPRIN-1 do leczenia i/lub zapobiegania nowotworowi
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ES2634249T3 (es) 2011-08-04 2017-09-27 Toray Industries, Inc. Composición farmacéutica para el tratamiento y/o la profilaxis del cáncer
PT2741085T (pt) 2011-08-04 2017-06-30 Toray Industries Método para a deteção de cancro prancreático

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CN102821789B (zh) 2016-03-02
KR101801667B1 (ko) 2017-11-27
HUE030742T2 (en) 2017-06-28
RU2597971C2 (ru) 2016-09-20
WO2011096533A1 (ja) 2011-08-11
KR20130033347A (ko) 2013-04-03
US8937160B2 (en) 2015-01-20
AU2011211698A1 (en) 2012-08-23
CA2788716A1 (en) 2011-08-11
ES2606173T3 (es) 2017-03-23
CA2788716C (en) 2019-06-18
AU2011211698B2 (en) 2015-07-16
BR112012018951B8 (pt) 2020-06-09
JPWO2011096533A1 (ja) 2013-06-13
BR112012018951A8 (pt) 2020-03-31
EP2532366B1 (en) 2016-09-07
PT2532366T (pt) 2016-12-20
EP2532366A1 (en) 2012-12-12
BR112012018951C8 (pt) 2020-06-23
BR112012018951B1 (pt) 2020-05-12
DK2532366T3 (da) 2017-01-02
CN102821789A (zh) 2012-12-12
BR112012018951A2 (pt) 2017-06-27
JP5742713B2 (ja) 2015-07-01
RU2012137504A (ru) 2014-03-10
EP2532366A4 (en) 2013-12-04
US20130045210A1 (en) 2013-02-21
MX2012009000A (es) 2012-08-31

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