MX340017B - Composicion farmaceutica para el tratamiento y/o prevencion del cancer. - Google Patents

Composicion farmaceutica para el tratamiento y/o prevencion del cancer.

Info

Publication number
MX340017B
MX340017B MX2012008996A MX2012008996A MX340017B MX 340017 B MX340017 B MX 340017B MX 2012008996 A MX2012008996 A MX 2012008996A MX 2012008996 A MX2012008996 A MX 2012008996A MX 340017 B MX340017 B MX 340017B
Authority
MX
Mexico
Prior art keywords
treating
antibody
medicinal composition
cancer
preventing cancer
Prior art date
Application number
MX2012008996A
Other languages
English (en)
Other versions
MX2012008996A (es
Inventor
Okano Fumiyoshi
Saito Takanori
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of MX2012008996A publication Critical patent/MX2012008996A/es
Publication of MX340017B publication Critical patent/MX340017B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015Breast
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053Skin, nerves, brain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/23Immunoglobulins specific features characterized by taxonomic origin from birds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a una proteína de antígeno de cáncer para ser específicamente expresada sobre las superficies de las células de cáncer y de este modo se proporciona el uso de un anticuerpo dirigido a la proteína de antígeno de cáncer como un agente para el tratamiento y/o prevención de un cáncer. Específicamente, la presente invención proporciona una composición farmacéutica para el tratamiento y/o prevención de un cáncer, que comprende un anticuerpo que comprende una región variable de cadena pesada que comprende SEQ ID NOS: 39, 40, y 41 y una región variable de cadena ligera que comprende SEQ ID NOS: 43, 44, y 45 o un fragmento de la misma como un ingrediente activo y que tiene reactividad inmunológica con una proteína CAPRIN-1.
MX2012008996A 2010-02-04 2011-02-04 Composicion farmaceutica para el tratamiento y/o prevencion del cancer. MX340017B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010023452 2010-02-04
PCT/JP2011/052384 WO2011096519A1 (ja) 2010-02-04 2011-02-04 癌の治療及び/又は予防用医薬組成物

Publications (2)

Publication Number Publication Date
MX2012008996A MX2012008996A (es) 2012-09-07
MX340017B true MX340017B (es) 2016-06-22

Family

ID=44355513

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012008996A MX340017B (es) 2010-02-04 2011-02-04 Composicion farmaceutica para el tratamiento y/o prevencion del cancer.

Country Status (16)

Country Link
US (1) US8709418B2 (es)
EP (1) EP2532680B1 (es)
JP (1) JP5845899B2 (es)
KR (1) KR101758117B1 (es)
CN (1) CN102822199B (es)
AU (1) AU2011211684B2 (es)
BR (1) BR112012019098B8 (es)
CA (1) CA2788547C (es)
DK (1) DK2532680T3 (es)
ES (1) ES2543174T3 (es)
HU (1) HUE025678T2 (es)
MX (1) MX340017B (es)
PL (1) PL2532680T3 (es)
PT (1) PT2532680E (es)
RU (1) RU2567657C2 (es)
WO (1) WO2011096519A1 (es)

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Also Published As

Publication number Publication date
CA2788547C (en) 2018-06-05
DK2532680T3 (da) 2015-07-20
CA2788547A1 (en) 2011-08-11
RU2567657C2 (ru) 2015-11-10
EP2532680A9 (en) 2014-12-17
US8709418B2 (en) 2014-04-29
ES2543174T3 (es) 2015-08-17
WO2011096519A1 (ja) 2011-08-11
EP2532680B1 (en) 2015-04-29
BR112012019098A2 (pt) 2018-03-27
BR112012019098B8 (pt) 2021-08-17
EP2532680A1 (en) 2012-12-12
PT2532680E (pt) 2015-09-14
EP2532680A4 (en) 2013-11-27
BR112012019098B1 (pt) 2021-07-06
CN102822199B (zh) 2014-10-15
HUE025678T2 (en) 2016-04-28
MX2012008996A (es) 2012-09-07
JPWO2011096519A1 (ja) 2013-06-13
AU2011211684A1 (en) 2012-08-23
CN102822199A (zh) 2012-12-12
KR20120125327A (ko) 2012-11-14
RU2012137505A (ru) 2014-03-10
US20120321641A1 (en) 2012-12-20
JP5845899B2 (ja) 2016-01-20
PL2532680T3 (pl) 2015-10-30
KR101758117B1 (ko) 2017-07-14
AU2011211684B2 (en) 2014-09-25

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