JP2017113019A5 - - Google Patents

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Publication number
JP2017113019A5
JP2017113019A5 JP2017027825A JP2017027825A JP2017113019A5 JP 2017113019 A5 JP2017113019 A5 JP 2017113019A5 JP 2017027825 A JP2017027825 A JP 2017027825A JP 2017027825 A JP2017027825 A JP 2017027825A JP 2017113019 A5 JP2017113019 A5 JP 2017113019A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
cdr
pharmaceutical composition
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Application number
JP2017027825A
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English (en)
Japanese (ja)
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JP2017113019A (ja
JP6363747B2 (ja
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Publication of JP2017113019A publication Critical patent/JP2017113019A/ja
Publication of JP2017113019A5 publication Critical patent/JP2017113019A5/ja
Application granted granted Critical
Publication of JP6363747B2 publication Critical patent/JP6363747B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017027825A 2011-04-01 2017-02-17 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体 Expired - Fee Related JP6363747B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161471101P 2011-04-01 2011-04-01
US61/471,101 2011-04-01

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2014502846A Division JP6170903B2 (ja) 2011-04-01 2012-03-30 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018122610A Division JP2018172411A (ja) 2011-04-01 2018-06-28 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体

Publications (3)

Publication Number Publication Date
JP2017113019A JP2017113019A (ja) 2017-06-29
JP2017113019A5 true JP2017113019A5 (enExample) 2017-10-19
JP6363747B2 JP6363747B2 (ja) 2018-07-25

Family

ID=46932389

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2014502846A Expired - Fee Related JP6170903B2 (ja) 2011-04-01 2012-03-30 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体
JP2017027825A Expired - Fee Related JP6363747B2 (ja) 2011-04-01 2017-02-17 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体
JP2018122610A Pending JP2018172411A (ja) 2011-04-01 2018-06-28 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体
JP2020176145A Withdrawn JP2021019619A (ja) 2011-04-01 2020-10-20 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2014502846A Expired - Fee Related JP6170903B2 (ja) 2011-04-01 2012-03-30 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2018122610A Pending JP2018172411A (ja) 2011-04-01 2018-06-28 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体
JP2020176145A Withdrawn JP2021019619A (ja) 2011-04-01 2020-10-20 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体

Country Status (37)

Country Link
US (5) US20140294832A1 (enExample)
EP (1) EP2694544B1 (enExample)
JP (4) JP6170903B2 (enExample)
KR (2) KR20190079698A (enExample)
CN (2) CN103797030B (enExample)
AU (3) AU2012236296A1 (enExample)
BR (1) BR112013025376A2 (enExample)
CA (2) CA2831907C (enExample)
CL (1) CL2013002811A1 (enExample)
CO (1) CO6890074A2 (enExample)
CR (1) CR20130499A (enExample)
CU (1) CU20130128A7 (enExample)
CY (1) CY1121538T1 (enExample)
DK (1) DK2694544T3 (enExample)
DO (1) DOP2013000218A (enExample)
EA (2) EA034214B1 (enExample)
EC (1) ECSP13012913A (enExample)
ES (1) ES2722824T3 (enExample)
GT (1) GT201300229A (enExample)
HK (1) HK1243426A1 (enExample)
HR (1) HRP20190467T1 (enExample)
HU (1) HUE042706T2 (enExample)
IL (4) IL228633B (enExample)
LT (1) LT2694544T (enExample)
MX (1) MX2013011218A (enExample)
MY (2) MY190951A (enExample)
PE (1) PE20141149A1 (enExample)
PH (4) PH12013502039B1 (enExample)
PL (1) PL2694544T3 (enExample)
PT (1) PT2694544T (enExample)
RS (1) RS58633B1 (enExample)
SG (2) SG193594A1 (enExample)
SI (1) SI2694544T1 (enExample)
TR (1) TR201905101T4 (enExample)
UA (1) UA113623C2 (enExample)
WO (1) WO2012135671A2 (enExample)
ZA (1) ZA201308169B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101792032B1 (ko) 2008-12-19 2017-11-02 백스터 인터내셔널 인코포레이티드 Tfpi 억제제 및 사용 방법
WO2010072691A1 (en) 2008-12-22 2010-07-01 Novo Nordisk A/S Antibodies against tissue factor pathway inhibitor
PT3345615T (pt) 2010-03-01 2020-01-17 Bayer Healthcare Llc Anticorpos monoclonais otimizados contra inibidor da via do fator tecidual (tfpi)
DK2547355T3 (en) 2010-03-19 2017-03-20 Baxalta GmbH TFPI INHIBITORS AND METHODS OF USE
PL2694544T3 (pl) * 2011-04-01 2019-07-31 Bayer Healthcare Llc Przeciwciała monoklonalne przeciwko inhibitorowi szlaku czynnika tkankowego (TFPI)
BR112014022435B1 (pt) 2012-03-21 2023-02-14 Takeda Pharmaceutical Company Limited Inibidores de tfpi e métodos de uso
US9975962B2 (en) 2012-03-30 2018-05-22 Bayer Healthcare Llc Thrombin/plasmin-regulated antibodies that bind TFPI
US9592297B2 (en) 2012-08-31 2017-03-14 Bayer Healthcare Llc Antibody and protein formulations
US9896513B2 (en) * 2013-03-15 2018-02-20 Novo Nordisk A/S Antibodies capable of specifically binding two epitopes on tissue factor pathway inhibitor
EP2970497B1 (en) 2013-03-15 2017-10-25 Bayer HealthCare LLC Anti-tfpi antibody variants with differential binding across ph range for improved pharmacokinetics
EP3022228B1 (en) 2013-07-19 2019-02-27 Novo Nordisk A/S Antibodies recognizing the n-terminal part of tissue factor pathway inhibitor capable of eliciting pro-coagulant activity
JP6783754B2 (ja) * 2014-09-17 2020-11-11 ノヴォ ノルディスク アー/エス 組織因子経路インヒビター(1〜161)上の2つのエピトープに結合する能力がある抗体
MY178445A (en) * 2015-02-25 2020-10-13 Mogam Inst Biomedical Res Novel antibody binding to tfpi and composition comprising the same
KR102438650B1 (ko) * 2015-08-19 2022-08-31 화이자 인코포레이티드 조직 인자 경로 억제제 항체 및 그의 용도
JP7444059B2 (ja) * 2018-07-25 2024-03-06 ソニーグループ株式会社 血液凝固系解析装置
CN112442127A (zh) * 2019-08-29 2021-03-05 苏州康宁杰瑞生物科技有限公司 针对tfpi的单克隆抗体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06153985A (ja) * 1992-11-16 1994-06-03 Teijin Ltd モノクローナル抗体
UA112050C2 (uk) * 2008-08-04 2016-07-25 БАЄР ХЕЛСКЕР ЛЛСі Терапевтична композиція, що містить моноклональне антитіло проти інгібітора шляху тканинного фактора (tfpi)
WO2010072691A1 (en) * 2008-12-22 2010-07-01 Novo Nordisk A/S Antibodies against tissue factor pathway inhibitor
PT3345615T (pt) * 2010-03-01 2020-01-17 Bayer Healthcare Llc Anticorpos monoclonais otimizados contra inibidor da via do fator tecidual (tfpi)
PL2694544T3 (pl) * 2011-04-01 2019-07-31 Bayer Healthcare Llc Przeciwciała monoklonalne przeciwko inhibitorowi szlaku czynnika tkankowego (TFPI)
US8613919B1 (en) * 2012-08-31 2013-12-24 Bayer Healthcare, Llc High concentration antibody and protein formulations
US9592297B2 (en) * 2012-08-31 2017-03-14 Bayer Healthcare Llc Antibody and protein formulations

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