JP2017113019A5 - - Google Patents

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Publication number
JP2017113019A5
JP2017113019A5 JP2017027825A JP2017027825A JP2017113019A5 JP 2017113019 A5 JP2017113019 A5 JP 2017113019A5 JP 2017027825 A JP2017027825 A JP 2017027825A JP 2017027825 A JP2017027825 A JP 2017027825A JP 2017113019 A5 JP2017113019 A5 JP 2017113019A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
cdr
pharmaceutical composition
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Application number
JP2017027825A
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English (en)
Japanese (ja)
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JP2017113019A (ja
JP6363747B2 (ja
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Publication of JP2017113019A publication Critical patent/JP2017113019A/ja
Publication of JP2017113019A5 publication Critical patent/JP2017113019A5/ja
Application granted granted Critical
Publication of JP6363747B2 publication Critical patent/JP6363747B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017027825A 2011-04-01 2017-02-17 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体 Expired - Fee Related JP6363747B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161471101P 2011-04-01 2011-04-01
US61/471,101 2011-04-01

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2014502846A Division JP6170903B2 (ja) 2011-04-01 2012-03-30 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018122610A Division JP2018172411A (ja) 2011-04-01 2018-06-28 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体

Publications (3)

Publication Number Publication Date
JP2017113019A JP2017113019A (ja) 2017-06-29
JP2017113019A5 true JP2017113019A5 (enExample) 2017-10-19
JP6363747B2 JP6363747B2 (ja) 2018-07-25

Family

ID=46932389

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2014502846A Expired - Fee Related JP6170903B2 (ja) 2011-04-01 2012-03-30 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体
JP2017027825A Expired - Fee Related JP6363747B2 (ja) 2011-04-01 2017-02-17 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体
JP2018122610A Pending JP2018172411A (ja) 2011-04-01 2018-06-28 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体
JP2020176145A Withdrawn JP2021019619A (ja) 2011-04-01 2020-10-20 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2014502846A Expired - Fee Related JP6170903B2 (ja) 2011-04-01 2012-03-30 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2018122610A Pending JP2018172411A (ja) 2011-04-01 2018-06-28 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体
JP2020176145A Withdrawn JP2021019619A (ja) 2011-04-01 2020-10-20 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体

Country Status (37)

Country Link
US (5) US20140294832A1 (enExample)
EP (1) EP2694544B1 (enExample)
JP (4) JP6170903B2 (enExample)
KR (2) KR20190079698A (enExample)
CN (2) CN107090046A (enExample)
AU (3) AU2012236296A1 (enExample)
BR (1) BR112013025376A2 (enExample)
CA (2) CA3068997A1 (enExample)
CL (1) CL2013002811A1 (enExample)
CO (1) CO6890074A2 (enExample)
CR (1) CR20130499A (enExample)
CU (1) CU20130128A7 (enExample)
CY (1) CY1121538T1 (enExample)
DK (1) DK2694544T3 (enExample)
DO (1) DOP2013000218A (enExample)
EA (2) EA201991704A3 (enExample)
EC (1) ECSP13012913A (enExample)
ES (1) ES2722824T3 (enExample)
GT (1) GT201300229A (enExample)
HK (1) HK1243426A1 (enExample)
HR (1) HRP20190467T1 (enExample)
HU (1) HUE042706T2 (enExample)
IL (4) IL228633B (enExample)
LT (1) LT2694544T (enExample)
MX (1) MX2013011218A (enExample)
MY (2) MY190951A (enExample)
PE (1) PE20141149A1 (enExample)
PH (4) PH12013502039B1 (enExample)
PL (1) PL2694544T3 (enExample)
PT (1) PT2694544T (enExample)
RS (1) RS58633B1 (enExample)
SG (2) SG193594A1 (enExample)
SI (1) SI2694544T1 (enExample)
TR (1) TR201905101T4 (enExample)
UA (1) UA113623C2 (enExample)
WO (1) WO2012135671A2 (enExample)
ZA (1) ZA201308169B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8962563B2 (en) 2009-12-21 2015-02-24 Baxter International, Inc. TFPI inhibitors and methods of use
LT2379096T (lt) 2008-12-19 2019-12-27 Baxalta GmbH Tfpi inhibitoriai ir vartojimo būdai
EP2379600B2 (en) 2008-12-22 2020-10-14 Novo Nordisk A/S Antibodies against tissue factor pathway inhibitor
SG183443A1 (en) 2010-03-01 2012-09-27 Bayer Healthcare Llc Optimized monoclonal antibodies against tissue factor pathway inhibitor (tfpi)
EP2547355B1 (en) 2010-03-19 2017-01-11 Baxalta GmbH Tfpi inhibitors and methods of use
JP6170903B2 (ja) * 2011-04-01 2017-07-26 バイエル・ヘルスケア・エルエルシーBayer HealthCare LLC 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体
CN107266574A (zh) * 2012-03-30 2017-10-20 拜尔健康护理有限责任公司 蛋白酶调节的抗体
US9592297B2 (en) 2012-08-31 2017-03-14 Bayer Healthcare Llc Antibody and protein formulations
WO2014140240A1 (en) 2013-03-15 2014-09-18 Novo Nordisk A/S Antibodies capable of specifically binding two epitopes on tissue factor pathway inhibitor
CN113788897A (zh) 2013-03-15 2021-12-14 拜尔健康护理有限责任公司 改善药代动力学的具有跨pH范围差异结合的抗TFPI抗体变体
CN105473619B (zh) * 2013-07-19 2020-12-15 诺和诺德股份有限公司 能够引起促凝血活性的识别组织因子途径抑制剂的n-末端部分的抗体
US11279771B2 (en) * 2014-09-17 2022-03-22 Novo Nordisk A/S Antibodies capable of binding two epitopes on tissue factor pathway inhibitor (1-161)
CN107428838B (zh) * 2015-02-25 2021-01-01 财团法人牧岩生命科学研究所 结合tfpi的新型抗体以及包含所述抗体的组合物
KR20230074843A (ko) * 2015-08-19 2023-05-31 화이자 인코포레이티드 조직 인자 경로 억제제 항체 및 그의 용도
WO2020021890A1 (ja) * 2018-07-25 2020-01-30 ソニー株式会社 血液凝固系解析装置
CN112442127A (zh) * 2019-08-29 2021-03-05 苏州康宁杰瑞生物科技有限公司 针对tfpi的单克隆抗体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06153985A (ja) * 1992-11-16 1994-06-03 Teijin Ltd モノクローナル抗体
UA112050C2 (uk) * 2008-08-04 2016-07-25 БАЄР ХЕЛСКЕР ЛЛСі Терапевтична композиція, що містить моноклональне антитіло проти інгібітора шляху тканинного фактора (tfpi)
EP2379600B2 (en) * 2008-12-22 2020-10-14 Novo Nordisk A/S Antibodies against tissue factor pathway inhibitor
SG183443A1 (en) * 2010-03-01 2012-09-27 Bayer Healthcare Llc Optimized monoclonal antibodies against tissue factor pathway inhibitor (tfpi)
JP6170903B2 (ja) * 2011-04-01 2017-07-26 バイエル・ヘルスケア・エルエルシーBayer HealthCare LLC 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体
US9592297B2 (en) * 2012-08-31 2017-03-14 Bayer Healthcare Llc Antibody and protein formulations
US8613919B1 (en) * 2012-08-31 2013-12-24 Bayer Healthcare, Llc High concentration antibody and protein formulations

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