JP2010521147A5 - - Google Patents

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Publication number
JP2010521147A5
JP2010521147A5 JP2009553239A JP2009553239A JP2010521147A5 JP 2010521147 A5 JP2010521147 A5 JP 2010521147A5 JP 2009553239 A JP2009553239 A JP 2009553239A JP 2009553239 A JP2009553239 A JP 2009553239A JP 2010521147 A5 JP2010521147 A5 JP 2010521147A5
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JP
Japan
Prior art keywords
antibody
antigen
binding fragment
seq
amino acid
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JP2009553239A
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English (en)
Japanese (ja)
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JP2010521147A (ja
JP5346820B2 (ja
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Priority claimed from PCT/IB2008/001527 external-priority patent/WO2008110937A2/en
Publication of JP2010521147A publication Critical patent/JP2010521147A/ja
Publication of JP2010521147A5 publication Critical patent/JP2010521147A5/ja
Application granted granted Critical
Publication of JP5346820B2 publication Critical patent/JP5346820B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009553239A 2007-03-13 2008-03-13 Ｈ５ｎ１亜型ａ型インフルエンザウィルスに対する抗体 Expired - Fee Related JP5346820B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89461207P 2007-03-13 2007-03-13
US60/894,612 2007-03-13
PCT/IB2008/001527 WO2008110937A2 (en) 2007-03-13 2008-03-13 Antibodies against h5n1 strains of influenza a virus

Publications (3)

Publication Number Publication Date
JP2010521147A JP2010521147A (ja) 2010-06-24
JP2010521147A5 true JP2010521147A5 (enExample) 2011-05-06
JP5346820B2 JP5346820B2 (ja) 2013-11-20

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ID=39760169

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009553239A Expired - Fee Related JP5346820B2 (ja) 2007-03-13 2008-03-13 Ｈ５ｎ１亜型ａ型インフルエンザウィルスに対する抗体

Country Status (5)

Country Link
US (2) US8124092B2 (enExample)
EP (1) EP2125886A2 (enExample)
JP (1) JP5346820B2 (enExample)
CN (1) CN102046654A (enExample)
WO (1) WO2008110937A2 (enExample)

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AU2006341615A1 (en) 2005-08-03 2007-10-18 Fraunhofer Usa, Inc. Compositions and methods for production of immunoglobulins
WO2008110937A2 (en) * 2007-03-13 2008-09-18 Humabs Llc Antibodies against h5n1 strains of influenza a virus
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AU2009275226B2 (en) * 2008-07-25 2015-05-14 Institute For Research In Biomedicine Neutralizing anti-influenza a virus antibodies and uses thereof
US8871207B2 (en) 2008-07-25 2014-10-28 Humabs, LLC Neutralizing anti-influenza A virus antibodies and uses thereof
US8734803B2 (en) 2008-09-28 2014-05-27 Ibio Inc. Humanized neuraminidase antibody and methods of use thereof
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AU2009306010B2 (en) 2008-10-22 2015-12-24 Institute For Research In Biomedicine Methods for producing antibodies from plasma cells
SG176003A1 (en) * 2009-05-11 2011-12-29 Crucell Holland Bv Human binding molecules capable of neutralizing influenza virus h3n2 and uses thereof
EP2483307A1 (en) 2009-09-29 2012-08-08 Fraunhofer USA, Inc. Influenza hemagglutinin antibodies, compositions, and related methods
EP2603237A4 (en) * 2010-08-12 2014-05-21 Theraclone Sciences Inc ANTI-HEMAGGLUTININE ANTIBODY COMPOSITIONS AND METHOD FOR THEIR USE
CN102775469B (zh) * 2011-05-12 2018-02-09 厦门大学 甲型流感病毒核衣壳蛋白的抗原表位及其用途
SI2734545T1 (sl) 2011-07-18 2019-06-28 Institute For Research In Biomedicine Protitelesa, ki nevtralizirajo virus influence A in njihova uporaba
JP2013087069A (ja) * 2011-10-17 2013-05-13 Toyobo Co Ltd Ｈ５亜型インフルエンザウイルスを特異的に認識するモノクローナル抗体
WO2013086052A2 (en) 2011-12-05 2013-06-13 Trellis Bioscience, Llc Antibodies useful in passive influenza immunization
US9233152B2 (en) 2012-01-12 2016-01-12 Temasek Life Sciences Laboratory Limited Monoclonal antibodies targeting neutralizing epitopes on H5 influenza virus of clade 2.3
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
EA201892509A1 (ru) 2012-11-13 2019-04-30 Дженентек, Инк. Антитела к гемагглютинину и способы применения
US11827693B2 (en) * 2013-03-14 2023-11-28 Contrafect Corporation Composition and methods based on neutralizing antibodies delivered intranasally for enhanced therapeutic efficacy
ES2837392T3 (es) * 2013-10-02 2021-06-30 Medimmune Llc Anticuerpos anti-influenza A neutralizantes y usos de los mismos
WO2015120097A2 (en) 2014-02-04 2015-08-13 Contrafect Corporation Antibodies useful in passive influenza immunization, and compositions, combinations and methods for use thereof
US10639370B2 (en) 2014-02-04 2020-05-05 Contrafect Corporation Antibodies useful in passive influenza immunization, and compositions, combinations and methods for use thereof
KR101628331B1 (ko) * 2014-03-28 2016-06-08 주식회사 녹십자엠에스 인플루엔자 a 바이러스 특이적 단클론 항체 및 이를 이용한 인플루엔자 감염 치료 및 진단 방법
JP6614523B2 (ja) * 2014-03-28 2019-12-04 地方独立行政法人神奈川県立産業技術総合研究所 インフルエンザウイルスのｒｎａ依存性ｒｎａポリメラーゼのｐｂ２サブユニットに対するモノクローナル抗体
CN106573154B (zh) 2014-07-15 2021-06-15 免疫医疗有限责任公司 中和抗乙型流感抗体及其用途
TWI702229B (zh) 2014-12-19 2020-08-21 美商再生元醫藥公司 流行性感冒病毒血球凝集素之人類抗體
CN108135994B (zh) 2015-05-13 2022-01-25 宾夕法尼亚州大学信托人 Aav-介导的抗-流感抗体的表达及其使用方法
BR112017025496A2 (pt) 2015-06-01 2018-08-07 Medimmune, Llc Moléculas de ligação neutralizantes anti- influenza e usos das mesmas
EP3374390A1 (en) 2015-11-13 2018-09-19 Visterra, Inc. Compositions and methods for treating and preventing influenza
US20190015509A1 (en) 2016-01-13 2019-01-17 Medimmune, Llc Method of treating influenza a
JP7104629B2 (ja) 2016-02-24 2022-07-21 ビステラ， インコーポレイテッド インフルエンザウイルスに対する抗体分子の製剤
PL238020B1 (pl) * 2016-09-12 2021-06-28 Inst Biotechnologii I Antybiotykow Kompozycja przeciwciał monoklonalnych przeciwko hemaglutyninie wirusów grypy serotypu H5 i jej zastosowanie, hybrydomy produkujące rzeczone przeciwciała, sposób diagnozowania infekcji wirusami grypy serotypu H5 oraz zestawy diagnostyczne
CA3052487A1 (en) 2017-02-28 2018-09-07 The Trustees Of The University Of Pennsylvania Influenza vaccines based on aav vectors
PE20191362A1 (es) 2017-02-28 2019-10-01 Univ Pennsylvania Novedoso vector del subtipo f del virus adenoasociado (aav) y usos de este
JOP20190200A1 (ar) 2017-02-28 2019-08-27 Univ Pennsylvania تركيبات نافعة في معالجة ضمور العضل النخاعي
TWI790120B (zh) 2017-06-02 2023-01-11 美商輝瑞大藥廠 對flt3具特異性之抗體及其用途
AU2020248404A1 (en) 2019-03-25 2021-09-30 Visterra, Inc. Compositions and methods for treating and preventing influenza
US20240288426A1 (en) * 2020-01-12 2024-08-29 Vanderbilt University Human antibodies to crimean congo hemorrhagic fever virus
WO2021202815A1 (en) * 2020-03-31 2021-10-07 Northeastern University Colorimetric and multiplexed isothermal rna-and antibody-based assay for sars-cov-2 and other viral diagnostics and cell analysis
CN114181302B (zh) * 2020-09-14 2023-03-24 东莞市朋志生物科技有限公司 针对甲型流感病毒的抗体、试剂盒和载体
US12319747B2 (en) * 2023-07-03 2025-06-03 Medicovestor, Inc. Methods of using anti-SP17 immunotherapeutics
US12364777B2 (en) 2023-10-20 2025-07-22 Medicovestor, Inc. Homodimeric antibodies for use in treating cancers and methods of use
US12116410B1 (en) 2023-12-26 2024-10-15 Medicovestor, Inc. Methods of manufacturing dimeric antibodies

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WO2003078600A2 (en) * 2002-03-13 2003-09-25 Kirin Beer Kabushiki Kaisha Human monoclonal antibodies to influenza m2 protein and methods of making and using same
JP5525688B2 (ja) 2005-08-19 2014-06-18 株式会社ビーエル インフルエンザウイルスｈ５亜型の免疫検出法
US8642513B2 (en) 2005-09-15 2014-02-04 Crucell Holland B.V. Method for preparing immunoglobulin libraries
GB0522460D0 (en) 2005-11-03 2005-12-14 Prendergast Patrick T Composition and method for the treatment of avian influenza
CN101379397A (zh) * 2006-01-26 2009-03-04 Hx诊断公司 H5亚型禽流感病毒血凝素蛋白的单克隆抗体或其结合活性片段及其用途
US20080014205A1 (en) 2006-05-15 2008-01-17 Lawrence Horowitz Neutralizing Antibodies to Influenza Viruses
US8192927B2 (en) * 2006-09-07 2012-06-05 Crucell Holland B.V. Human bind molecules capable of neutralizing influenza virus h5n1 and uses thereof
CN101541832B (zh) * 2006-09-07 2014-11-12 克鲁塞尔荷兰公司 能中和流感病毒h5n1的人结合分子及其应用
US20100150941A1 (en) 2006-09-13 2010-06-17 Dso National Laboratories Hemagglutinin antibody and uses thereof
WO2008033159A1 (en) 2006-09-15 2008-03-20 Fraunhofer Usa, Inc. Influenza antibodies, compositions, and related methods
WO2008110937A2 (en) * 2007-03-13 2008-09-18 Humabs Llc Antibodies against h5n1 strains of influenza a virus

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