JP2016020389A5 - - Google Patents
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- Publication number
- JP2016020389A5 JP2016020389A5 JP2015208653A JP2015208653A JP2016020389A5 JP 2016020389 A5 JP2016020389 A5 JP 2016020389A5 JP 2015208653 A JP2015208653 A JP 2015208653A JP 2015208653 A JP2015208653 A JP 2015208653A JP 2016020389 A5 JP2016020389 A5 JP 2016020389A5
- Authority
- JP
- Japan
- Prior art keywords
- mmp9
- binding protein
- chain polypeptide
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101000990902 Homo sapiens Matrix metalloproteinase-9 Proteins 0.000 claims description 30
- 229920001184 polypeptide Polymers 0.000 claims description 20
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 20
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 20
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 14
- 230000000694 effects Effects 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 8
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims description 7
- 206010028980 Neoplasm Diseases 0.000 claims description 6
- 102000006496 Immunoglobulin Heavy Chains Human genes 0.000 claims description 4
- 108010019476 Immunoglobulin Heavy Chains Proteins 0.000 claims description 4
- 102000013463 Immunoglobulin Light Chains Human genes 0.000 claims description 4
- 108010065825 Immunoglobulin Light Chains Proteins 0.000 claims description 4
- 230000002255 enzymatic effect Effects 0.000 claims description 4
- 239000012634 fragment Substances 0.000 claims description 4
- 239000008194 pharmaceutical composition Substances 0.000 claims description 4
- 238000001514 detection method Methods 0.000 claims description 3
- 102000054439 human MMP9 Human genes 0.000 claims description 3
- 239000004235 Orange GGN Substances 0.000 claims description 2
- 125000000539 amino acid group Chemical group 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 230000002401 inhibitory effect Effects 0.000 claims description 2
- 230000005764 inhibitory process Effects 0.000 claims description 2
- 230000036963 noncompetitive effect Effects 0.000 claims description 2
- 102100030412 Matrix metalloproteinase-9 Human genes 0.000 claims 27
- 102000023732 binding proteins Human genes 0.000 description 15
- 108091008324 binding proteins Proteins 0.000 description 15
- 239000000523 sample Substances 0.000 description 6
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000013074 reference sample Substances 0.000 description 2
- 241000282412 Homo Species 0.000 description 1
- 230000009260 cross reactivity Effects 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37788610P | 2010-08-27 | 2010-08-27 | |
| US61/377,886 | 2010-08-27 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013526186A Division JP5878538B2 (ja) | 2010-08-27 | 2011-08-26 | マトリクスメタロプロティナーゼ９に対する抗体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017159712A Division JP6435381B2 (ja) | 2010-08-27 | 2017-08-22 | マトリクスメタロプロティナーゼ９に対する抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016020389A JP2016020389A (ja) | 2016-02-04 |
| JP2016020389A5 true JP2016020389A5 (enExample) | 2016-05-19 |
| JP6198797B2 JP6198797B2 (ja) | 2017-09-20 |
Family
ID=45724100
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013526186A Active JP5878538B2 (ja) | 2010-08-27 | 2011-08-26 | マトリクスメタロプロティナーゼ９に対する抗体 |
| JP2015208653A Active JP6198797B2 (ja) | 2010-08-27 | 2015-10-23 | マトリクスメタロプロティナーゼ９に対する抗体 |
| JP2017159712A Active JP6435381B2 (ja) | 2010-08-27 | 2017-08-22 | マトリクスメタロプロティナーゼ９に対する抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013526186A Active JP5878538B2 (ja) | 2010-08-27 | 2011-08-26 | マトリクスメタロプロティナーゼ９に対する抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017159712A Active JP6435381B2 (ja) | 2010-08-27 | 2017-08-22 | マトリクスメタロプロティナーゼ９に対する抗体 |
Country Status (29)
| Country | Link |
|---|---|
| US (7) | US8377443B2 (enExample) |
| EP (1) | EP2608809B1 (enExample) |
| JP (3) | JP5878538B2 (enExample) |
| KR (4) | KR101827048B1 (enExample) |
| CN (2) | CN103140240B (enExample) |
| AP (2) | AP2016009448A0 (enExample) |
| AU (1) | AU2011293125B2 (enExample) |
| BR (1) | BR112013004579B1 (enExample) |
| CA (1) | CA2808418C (enExample) |
| CL (1) | CL2013000535A1 (enExample) |
| CO (1) | CO6680656A2 (enExample) |
| CR (1) | CR20130132A (enExample) |
| EA (1) | EA031729B1 (enExample) |
| EC (1) | ECSP13012525A (enExample) |
| ES (1) | ES2739505T3 (enExample) |
| IL (2) | IL224614A (enExample) |
| MA (1) | MA34527B1 (enExample) |
| MX (1) | MX342413B (enExample) |
| NZ (2) | NZ701444A (enExample) |
| PE (1) | PE20131376A1 (enExample) |
| PH (2) | PH12013500347A1 (enExample) |
| PL (1) | PL2608809T3 (enExample) |
| PT (1) | PT2608809T (enExample) |
| SG (2) | SG188224A1 (enExample) |
| SI (1) | SI2608809T1 (enExample) |
| TR (1) | TR201910348T4 (enExample) |
| UA (1) | UA109908C2 (enExample) |
| WO (1) | WO2012027721A2 (enExample) |
| ZA (2) | ZA201301338B (enExample) |
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| DK2663579T3 (en) | 2011-01-14 | 2017-07-31 | Univ California | THERAPEUTIC ANTIBODIES AGAINST ROR-1 PROTEIN AND PROCEDURES FOR USE THEREOF |
| WO2013130905A1 (en) * | 2012-02-29 | 2013-09-06 | Gilead Biologics, Inc. | Antibodies to matrix metalloproteinase 9 |
| MD20140107A2 (ro) * | 2012-02-29 | 2015-03-31 | Gilead Biologics, Inc. | Anticorpi împotriva metaloproteinazei 9 din matrice |
| MX2015014053A (es) * | 2013-04-05 | 2016-04-07 | Claudia Zylberberg | Metaloproteinasas de matriz y sus usos. |
| AU2014354769A1 (en) | 2013-11-26 | 2016-05-26 | Gilead Sciences, Inc. | Therapies for treating myeloproliferative disorders |
| EP3102238A1 (en) | 2014-01-20 | 2016-12-14 | Gilead Sciences, Inc. | Therapies for treating cancers |
| EP2985295A1 (en) * | 2014-08-13 | 2016-02-17 | Calypso Biotech SA | Antibodies specific for MMP9 |
| EP2985296A1 (en) * | 2014-08-13 | 2016-02-17 | Calypso Biotech SA | Antibodies specific for MMP9 |
| TW201639573A (zh) | 2015-02-03 | 2016-11-16 | 吉李德科學股份有限公司 | 有關治療癌症之合併治療 |
| SI3321265T1 (sl) | 2015-03-04 | 2020-07-31 | Gilead Sciences, Inc. | Spojine 4,6-diamino-pirido(3,2-d)pirimidina in njihova uporaba kot modulatorji toličnih receptorjev |
| CN105037553B (zh) * | 2015-08-20 | 2018-04-17 | 内蒙古蒙元生物基因科技有限公司 | 一种能够检测癌症的免疫球蛋白 |
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