JP2015534564A5 - - Google Patents
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- Publication number
- JP2015534564A5 JP2015534564A5 JP2015535889A JP2015535889A JP2015534564A5 JP 2015534564 A5 JP2015534564 A5 JP 2015534564A5 JP 2015535889 A JP2015535889 A JP 2015535889A JP 2015535889 A JP2015535889 A JP 2015535889A JP 2015534564 A5 JP2015534564 A5 JP 2015534564A5
- Authority
- JP
- Japan
- Prior art keywords
- lingo
- combination
- combination according
- antibody molecule
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261711638P | 2012-10-09 | 2012-10-09 | |
| US61/711,638 | 2012-10-09 | ||
| PCT/US2013/063873 WO2014058875A2 (en) | 2012-10-09 | 2013-10-08 | Combination therapies and uses for treatment of demyelinating disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017247590A Division JP2018044014A (ja) | 2012-10-09 | 2017-12-25 | 脱髄障害の治療のための併用療法および使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015534564A JP2015534564A (ja) | 2015-12-03 |
| JP2015534564A5 true JP2015534564A5 (enExample) | 2016-11-24 |
Family
ID=49484444
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015535889A Withdrawn JP2015534564A (ja) | 2012-10-09 | 2013-10-08 | 脱髄障害の治療のための併用療法および使用 |
| JP2017247590A Withdrawn JP2018044014A (ja) | 2012-10-09 | 2017-12-25 | 脱髄障害の治療のための併用療法および使用 |
| JP2020004952A Withdrawn JP2020055881A (ja) | 2012-10-09 | 2020-01-16 | 脱髄障害の治療のための併用療法および使用 |
| JP2021176294A Pending JP2022023182A (ja) | 2012-10-09 | 2021-10-28 | 脱髄障害の治療のための併用療法および使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017247590A Withdrawn JP2018044014A (ja) | 2012-10-09 | 2017-12-25 | 脱髄障害の治療のための併用療法および使用 |
| JP2020004952A Withdrawn JP2020055881A (ja) | 2012-10-09 | 2020-01-16 | 脱髄障害の治療のための併用療法および使用 |
| JP2021176294A Pending JP2022023182A (ja) | 2012-10-09 | 2021-10-28 | 脱髄障害の治療のための併用療法および使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20150238602A1 (enExample) |
| EP (2) | EP3750560A3 (enExample) |
| JP (4) | JP2015534564A (enExample) |
| KR (2) | KR102257645B1 (enExample) |
| CN (2) | CN109364250A (enExample) |
| AU (3) | AU2013329421A1 (enExample) |
| BR (1) | BR112015007780A2 (enExample) |
| CA (1) | CA2887682A1 (enExample) |
| EA (1) | EA201590709A1 (enExample) |
| HK (1) | HK1213794A1 (enExample) |
| IL (2) | IL238117B (enExample) |
| MX (2) | MX2015004436A (enExample) |
| WO (1) | WO2014058875A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2315779A2 (en) | 2008-07-09 | 2011-05-04 | Biogen Idec MA Inc. | Compositions comprising antibodies to lingo or fragments thereof |
| US9796780B2 (en) | 2012-05-14 | 2017-10-24 | Biogen Ma Inc. | LINGO-2 antagonists for treatment of conditions involving motor neurons |
| EP3194628A4 (en) * | 2014-09-19 | 2018-02-14 | Ionis Pharmaceuticals, Inc. | Antisense compounds and uses thereof |
| HUE057865T2 (hu) | 2014-12-11 | 2022-06-28 | Actelion Pharmaceuticals Ltd | A poneszimodra, egy szelektív S1P1 receptor agonistára vonatkozó adagolási rend |
| MA41139B1 (fr) | 2014-12-11 | 2026-02-27 | Laboratoires Juvise Pharmaceuticals | Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque |
| WO2016112270A1 (en) * | 2015-01-08 | 2016-07-14 | Biogen Ma Inc. | Lingo-1 antagonists and uses for treatment of demyelinating disorders |
| WO2016156468A1 (en) | 2015-03-31 | 2016-10-06 | Vhsquared Limited | Polypeptides |
| AU2016239949A1 (en) | 2015-03-31 | 2017-09-07 | Sorriso Pharmaceuticals, Inc. | Peptide construct having a protease-cleavable linker |
| US10118904B2 (en) | 2015-06-05 | 2018-11-06 | Vertex Pharmaceuticals Incorporated | Triazoles for the treatment of Demyelinating Diseases |
| CA2998183A1 (en) * | 2015-09-11 | 2017-03-16 | AbbVie Deutschland GmbH & Co. KG | Methods for treating relapsing forms of multiple sclerosis |
| WO2018013714A1 (en) * | 2016-07-13 | 2018-01-18 | Biogen Ma Inc. | Dosage regimens of lingo-1 antagonists and uses for treatment of demyelinating disorders |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| AU2017319728B2 (en) | 2016-08-31 | 2024-09-05 | Mapi Pharma Ltd | Depot systems comprising glatiramer acetate |
| WO2018106646A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Aminotriazoles for the treatment of demyelinating diseases |
| WO2018106641A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Pyrazoles for the treatment of demyelinating diseases |
| WO2018106643A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Heterocyclic azoles for the treatment of demyelinating diseases |
| IL316573A (en) | 2017-03-26 | 2024-12-01 | Mapi Pharma Ltd | Storage systems containing glatiramer acetate for the treatment of multiple sclerosis |
| CN110650749A (zh) * | 2017-05-15 | 2020-01-03 | 肿瘤免疫股份有限公司 | 使用可溶性cd24进行神经保护和髓鞘再生的方法 |
| US11412968B2 (en) | 2017-09-12 | 2022-08-16 | Get Together, Inc | System and method for a digital therapeutic delivery of generalized clinician tips (GCT) |
| SG11202010087UA (en) * | 2018-04-13 | 2020-11-27 | Mordechai Chevion | Compositions and methods for treatment of demyelination |
| CA3144566A1 (en) | 2019-06-21 | 2020-12-24 | Sorriso Pharmaceuticals, Inc. | Polypeptides |
| US12570736B2 (en) | 2019-06-21 | 2026-03-10 | Sorriso Pharmaceuticals, Inc. | Compositions |
| JP7692844B2 (ja) | 2019-06-21 | 2025-06-16 | ソリッソ ファーマシューティカルズ,インク. | ポリペプチド |
| CN113584041A (zh) * | 2021-04-15 | 2021-11-02 | 浙江警察学院 | 一种转基因斑马鱼(mbp:egfp)脱脊髓疾病模型的构建方法 |
| KR102898110B1 (ko) * | 2022-06-13 | 2025-12-12 | 고려대학교 산학협력단 | 키나아제 저해제를 유효성분으로 포함하는 탈수초성 질환 예방 또는 치료용 약학적 조성물 |
| EP4720125A1 (en) | 2023-05-30 | 2026-04-08 | Paragon Therapeutics, Inc. | Alpha4beta7 integrin antibody compositions and methods of use |
| EP4762093A1 (en) | 2023-08-14 | 2026-06-24 | Paragon Therapeutics, Inc. | Alpha 4 beta 7 integrin binding proteins and methods of use |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| GB2183662B (en) | 1985-04-01 | 1989-01-25 | Celltech Ltd | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| US5116742A (en) | 1986-12-03 | 1992-05-26 | University Patents, Inc. | RNA ribozyme restriction endoribonucleases and methods |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| DE68927933T2 (de) | 1988-09-02 | 1997-08-14 | Dyax Corp | Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| WO1991000906A1 (en) | 1989-07-12 | 1991-01-24 | Genetics Institute, Inc. | Chimeric and transgenic animals capable of producing human antibodies |
| EP1690935A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| ES2139598T3 (es) | 1990-07-10 | 2000-02-16 | Medical Res Council | Procedimientos para la produccion de miembros de parejas de union especifica. |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| CA2090473A1 (en) | 1990-08-29 | 1992-03-01 | Robert M. Kay | Homologous recombinatin in mammalian cells |
| ES2246502T3 (es) | 1990-08-29 | 2006-02-16 | Genpharm International, Inc. | Animales no humanos transgenicos capaces de producir anticuerpos heterologos. |
| DE69129154T2 (de) | 1990-12-03 | 1998-08-20 | Genentech, Inc., South San Francisco, Calif. | Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften |
| DE69233697T2 (de) | 1991-03-01 | 2008-01-24 | Dyax Corp., Cambridge | Verfahren zur Entwicklung von bindenden Mikroproteinen |
| PT100379B (pt) | 1991-04-10 | 1999-01-29 | Scripps Research Inst | Bibliotecas de receptores heterodimericos usando fagomideos |
| DE69233482T2 (de) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| IE922437A1 (en) | 1991-07-25 | 1993-01-27 | Idec Pharma Corp | Recombinant antibodies for human therapy |
| DE69334275D1 (de) | 1992-08-21 | 2009-05-20 | Univ Bruxelles | Immunoglobuline ohne Leichtkette |
| CA2149326C (en) | 1992-11-13 | 2007-04-17 | Mitchell E. Reff | Fully impaired consensus kozak sequences for mammalian expression |
| US5736137A (en) | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| SG44845A1 (en) | 1993-01-12 | 1997-12-19 | Biogen Inc | Recombitant anti-vla4 antibody molecules |
| WO1994017828A2 (en) | 1993-02-09 | 1994-08-18 | Biogen, Inc. | Treatment for insulin dependent diabetes |
| DE4343034C1 (de) * | 1993-12-16 | 1995-06-08 | Rentschler Arzneimittel | Verwendung von Pentoxifyllin zur Behandlung von Multipler Sklerose |
| US5840299A (en) | 1994-01-25 | 1998-11-24 | Athena Neurosciences, Inc. | Humanized antibodies against leukocyte adhesion molecule VLA-4 |
| GB9524973D0 (en) | 1995-12-06 | 1996-02-07 | Lynxvale Ltd | Viral vectors |
| US20030143204A1 (en) | 2001-07-27 | 2003-07-31 | Lewis David L. | Inhibition of RNA function by delivery of inhibitors to animal cells |
| RO120148B1 (ro) | 1997-03-14 | 2005-09-30 | Idec Pharmaceuticals Corporation | Sistem vector şi procedeu de inserţie a unui fragment adn, în genomul celulelor de mamifere |
| JP2003526367A (ja) | 2000-03-16 | 2003-09-09 | ジェネティカ インコーポレイテッド | Rna干渉の方法とrna干渉組成物 |
| AU2002319544B2 (en) | 2001-08-10 | 2008-07-10 | Aberdeen University | Antigen binding domains from fish |
| US20030157641A1 (en) | 2001-11-16 | 2003-08-21 | Idec Pharmaceuticals Corporation | Polycistronic expression of antibodies |
| US20030166282A1 (en) | 2002-02-01 | 2003-09-04 | David Brown | High potency siRNAS for reducing the expression of target genes |
| SI1471974T1 (sl) * | 2002-02-06 | 2007-12-31 | Ares Trading Sa | Tumorje nekrotizirajoäśi faktor, kombiniran z interferonom, pri demielinizirajoäśih boleznih |
| WO2003093430A2 (en) | 2002-05-03 | 2003-11-13 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for use in preparing sirnas |
| CN1685063B (zh) | 2002-08-12 | 2011-12-21 | 新英格兰生物实验室公司 | 与基因沉默相关的方法和组合物 |
| JP2007521249A (ja) * | 2003-01-24 | 2007-08-02 | エラン ファーマシューティカルズ,インコーポレイテッド | 脱髄疾患および麻痺のための組成物ならびに再有髄化剤を投与することによるそれらの治療 |
| ZA200505869B (en) * | 2003-01-24 | 2006-11-29 | Elan Pharm Inc | Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents |
| PL1606409T3 (pl) | 2003-03-19 | 2011-02-28 | Biogen Ma Inc | Białko wiążące receptor Nogo |
| KR20040086884A (ko) | 2003-03-22 | 2004-10-13 | 제일모직주식회사 | 난연성 열가소성 수지 조성물 |
| PT1776136E (pt) | 2004-06-24 | 2012-12-05 | Biogen Idec Inc | Tratamento de estados que envolvem desmielinização |
| US8128926B2 (en) | 2007-01-09 | 2012-03-06 | Biogen Idec Ma Inc. | Sp35 antibodies and uses thereof |
| GEP20125693B (en) * | 2007-01-09 | 2012-11-26 | Biogen Idec Inc | Sp35 antibodies and usage thereof |
| EP2315779A2 (en) * | 2008-07-09 | 2011-05-04 | Biogen Idec MA Inc. | Compositions comprising antibodies to lingo or fragments thereof |
| IT1395574B1 (it) | 2009-09-14 | 2012-10-16 | Guala Dispensing Spa | Dispositivo di erogazione |
| CN106278999B (zh) | 2011-02-07 | 2019-10-25 | 比奥根Ma公司 | S1p调节剂 |
| GB201103526D0 (en) * | 2011-03-02 | 2011-04-13 | Summit Corp Plc | Selective glycosidase inhibitors and uses thereof |
-
2013
- 2013-10-08 MX MX2015004436A patent/MX2015004436A/es unknown
- 2013-10-08 KR KR1020157012062A patent/KR102257645B1/ko not_active Expired - Fee Related
- 2013-10-08 EP EP20173044.7A patent/EP3750560A3/en not_active Withdrawn
- 2013-10-08 CA CA2887682A patent/CA2887682A1/en not_active Abandoned
- 2013-10-08 HK HK16101834.0A patent/HK1213794A1/zh unknown
- 2013-10-08 EP EP13780458.9A patent/EP2906240A2/en not_active Withdrawn
- 2013-10-08 KR KR1020217015388A patent/KR20210063443A/ko not_active Ceased
- 2013-10-08 WO PCT/US2013/063873 patent/WO2014058875A2/en not_active Ceased
- 2013-10-08 AU AU2013329421A patent/AU2013329421A1/en not_active Abandoned
- 2013-10-08 JP JP2015535889A patent/JP2015534564A/ja not_active Withdrawn
- 2013-10-08 CN CN201811360254.9A patent/CN109364250A/zh active Pending
- 2013-10-08 BR BR112015007780A patent/BR112015007780A2/pt not_active Application Discontinuation
- 2013-10-08 US US14/434,292 patent/US20150238602A1/en not_active Abandoned
- 2013-10-08 CN CN201380063471.0A patent/CN104870014A/zh active Pending
- 2013-10-08 EA EA201590709A patent/EA201590709A1/ru unknown
-
2015
- 2015-04-02 IL IL23811715A patent/IL238117B/en active IP Right Grant
- 2015-04-08 MX MX2020006431A patent/MX2020006431A/es unknown
-
2017
- 2017-12-25 JP JP2017247590A patent/JP2018044014A/ja not_active Withdrawn
-
2018
- 2018-02-20 US US15/900,369 patent/US20190038744A1/en not_active Abandoned
- 2018-05-25 AU AU2018203688A patent/AU2018203688A1/en not_active Abandoned
-
2019
- 2019-10-06 IL IL269852A patent/IL269852B/en unknown
- 2019-12-10 US US16/708,695 patent/US20200276303A1/en not_active Abandoned
-
2020
- 2020-01-16 JP JP2020004952A patent/JP2020055881A/ja not_active Withdrawn
- 2020-05-15 AU AU2020203196A patent/AU2020203196A1/en not_active Abandoned
- 2020-11-30 US US17/107,554 patent/US20210260185A1/en not_active Abandoned
-
2021
- 2021-10-28 JP JP2021176294A patent/JP2022023182A/ja active Pending
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