JP2013531491A5 - - Google Patents
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- Publication number
- JP2013531491A5 JP2013531491A5 JP2013513709A JP2013513709A JP2013531491A5 JP 2013531491 A5 JP2013531491 A5 JP 2013531491A5 JP 2013513709 A JP2013513709 A JP 2013513709A JP 2013513709 A JP2013513709 A JP 2013513709A JP 2013531491 A5 JP2013531491 A5 JP 2013531491A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- variant
- amino acid
- acid sequence
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 5
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 108700042778 Antimicrobial Peptides Proteins 0.000 claims 2
- 102000044503 Antimicrobial Peptides Human genes 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000003910 polypeptide antibiotic agent Substances 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- 230000000845 anti-microbial effect Effects 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10165773 | 2010-06-12 | ||
| EP10165773.2 | 2010-06-12 | ||
| EP10166483 | 2010-06-18 | ||
| EP10166483.7 | 2010-06-18 | ||
| EP10176204.5 | 2010-09-10 | ||
| EP10176204 | 2010-09-10 | ||
| PCT/EP2011/059689 WO2011154525A1 (en) | 2010-06-12 | 2011-06-10 | Antimicrobial peptide variants and polynucleotides encoding same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013531491A JP2013531491A (ja) | 2013-08-08 |
| JP2013531491A5 true JP2013531491A5 (enExample) | 2014-07-31 |
| JP6120769B2 JP6120769B2 (ja) | 2017-04-26 |
Family
ID=44246475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013513709A Active JP6120769B2 (ja) | 2010-06-12 | 2011-06-10 | 抗菌ペプチド改変体及びそれをコードするポリヌクレオチド |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US8835604B2 (enExample) |
| EP (1) | EP2580235B1 (enExample) |
| JP (1) | JP6120769B2 (enExample) |
| CN (1) | CN103068840B (enExample) |
| AR (1) | AR081866A1 (enExample) |
| BR (1) | BR112012031049A2 (enExample) |
| DK (1) | DK2580235T3 (enExample) |
| ES (1) | ES2699734T3 (enExample) |
| RU (1) | RU2611173C2 (enExample) |
| TW (1) | TWI654933B (enExample) |
| WO (1) | WO2011154525A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100227803A1 (en) * | 2005-12-14 | 2010-09-09 | Novozymes A/S | Polypeptides having antimicrobial activity and polynucleotides encoding same |
| KR20160144071A (ko) | 2015-06-08 | 2016-12-16 | 이주호 | 토출 작동 중 역방향 유입이 방지되는 팬 보조장치 |
| CN107188944B (zh) * | 2017-06-08 | 2020-07-07 | 中国农业科学院饲料研究所 | 海蚯蚓抗菌肽nz17074衍生肽n6及其应用 |
| CN107266547A (zh) * | 2017-06-26 | 2017-10-20 | 北京生泰云科技有限公司 | 海蚯蚓抗菌肽nz17074衍生肽n2及其应用 |
| US12173343B2 (en) | 2018-06-06 | 2024-12-24 | Syngulon Sa | Engineering antimicrobial peptides |
| RU2721273C1 (ru) * | 2019-04-22 | 2020-05-18 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Пептид никомицин из морского кольчатого червя nicomache minor, обладающий антимикробным и противоопухолевым действием. |
| CN110754400B (zh) * | 2019-10-28 | 2022-04-26 | 长江大学 | 一种提高黄鳝苗种人工孵化率的方法 |
| EP4198045A1 (en) * | 2021-12-16 | 2023-06-21 | Université de Lille | Antimicrobial peptides, variants and chemical analogues thereof and their uses |
| WO2024218715A1 (en) | 2023-04-19 | 2024-10-24 | Btl Healthcare Technologies A.S. | Culture media based on protein hydrolysate and a process for preparing thereof |
| US12668774B2 (en) | 2023-10-12 | 2026-06-30 | Btl Healthcare Technologies A.S. | Product, system and method of cell cultivation |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| PT97110B (pt) | 1990-03-23 | 1998-11-30 | Gist Brocades Nv | Processo para catalisar reaccoes acelaraveis por enzimas, mediante adicao ao meio reaccional de sementes de plantas transgenicas e para obtencao das referidas sementes |
| US6395966B1 (en) | 1990-08-09 | 2002-05-28 | Dekalb Genetics Corp. | Fertile transgenic maize plants containing a gene encoding the pat protein |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| DE4343591A1 (de) | 1993-12-21 | 1995-06-22 | Evotec Biosystems Gmbh | Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| CA2191718A1 (en) | 1994-06-03 | 1995-12-14 | Randy M. Berka | Phosphonyldipeptides useful in the treatment of cardiovascular diseases |
| ATE294871T1 (de) | 1994-06-30 | 2005-05-15 | Novozymes Biotech Inc | Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren |
| JP5043254B2 (ja) | 1998-10-26 | 2012-10-10 | ノボザイムス アクティーゼルスカブ | 糸状面細胞内の問題のｄｎａライブラリーの作製及びスクリーニング |
| EP1194572A2 (en) | 1999-03-22 | 2002-04-10 | Novozymes Biotech, Inc. | Promoter sequences derived from fusarium venenatum and uses thereof |
| US7151204B2 (en) | 2001-01-09 | 2006-12-19 | Monsanto Technology Llc | Maize chloroplast aldolase promoter compositions and methods for use thereof |
| EP1421187B1 (en) | 2001-07-27 | 2007-10-10 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Systems for in vivo site-directed mutagenesis using oligonucleotides |
| CN1950396A (zh) * | 2004-02-24 | 2007-04-18 | 联邦科学技术研究组织 | 抗真菌肽 |
| AR052947A1 (es) * | 2005-03-18 | 2007-04-11 | Novozymes As | Polipeptidos que tienen actividad antimicrobiana y polinucleotidos que codifican para los mismos |
| AU2006283904B2 (en) * | 2005-08-26 | 2012-07-12 | Novozymes Adenium Biotech A/S | Polypeptides having antimicrobial activity and polynucleotides encoding same |
-
2011
- 2011-06-02 US US13/151,600 patent/US8835604B2/en active Active
- 2011-06-03 TW TW100119540A patent/TWI654933B/zh not_active IP Right Cessation
- 2011-06-10 BR BR112012031049A patent/BR112012031049A2/pt not_active Application Discontinuation
- 2011-06-10 RU RU2012148781A patent/RU2611173C2/ru not_active IP Right Cessation
- 2011-06-10 WO PCT/EP2011/059689 patent/WO2011154525A1/en not_active Ceased
- 2011-06-10 JP JP2013513709A patent/JP6120769B2/ja active Active
- 2011-06-10 CN CN201180038676.4A patent/CN103068840B/zh not_active Expired - Fee Related
- 2011-06-10 AR ARP110102030A patent/AR081866A1/es unknown
- 2011-06-10 DK DK11724247.9T patent/DK2580235T3/en active
- 2011-06-10 ES ES11724247T patent/ES2699734T3/es active Active
- 2011-06-10 EP EP11724247.9A patent/EP2580235B1/en not_active Not-in-force
-
2014
- 2014-08-11 US US14/456,139 patent/US20150031601A1/en not_active Abandoned
-
2016
- 2016-02-13 US US15/043,547 patent/US20160158317A1/en not_active Abandoned
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