JP6120769B2 - 抗菌ペプチド改変体及びそれをコードするポリヌクレオチド - Google Patents

抗菌ペプチド改変体及びそれをコードするポリヌクレオチド Download PDF

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JP6120769B2
JP6120769B2 JP2013513709A JP2013513709A JP6120769B2 JP 6120769 B2 JP6120769 B2 JP 6120769B2 JP 2013513709 A JP2013513709 A JP 2013513709A JP 2013513709 A JP2013513709 A JP 2013513709A JP 6120769 B2 JP6120769 B2 JP 6120769B2
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seq
variant
peptide
amino acid
sequence
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JP2013531491A (ja
JP2013531491A5 (enExample
Inventor
クリステンセン ヘーエンハウク ハンス−ヘンリク
クリステンセン ヘーエンハウク ハンス−ヘンリク
ホルセ ミューギン ペル
ホルセ ミューギン ペル
クルーセ トマス
クルーセ トマス
ラベントス セグラ ドロテア
ラベントス セグラ ドロテア
サンバン ドーテ
サンバン ドーテ
ネベ ソレン
ネベ ソレン
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アデニウム バイオテック アンパーツゼルスカブ
アデニウム バイオテック アンパーツゼルスカブ
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1767Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2013513709A 2010-06-12 2011-06-10 抗菌ペプチド改変体及びそれをコードするポリヌクレオチド Active JP6120769B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP10165773 2010-06-12
EP10165773.2 2010-06-12
EP10166483 2010-06-18
EP10166483.7 2010-06-18
EP10176204.5 2010-09-10
EP10176204 2010-09-10
PCT/EP2011/059689 WO2011154525A1 (en) 2010-06-12 2011-06-10 Antimicrobial peptide variants and polynucleotides encoding same

Publications (3)

Publication Number Publication Date
JP2013531491A JP2013531491A (ja) 2013-08-08
JP2013531491A5 JP2013531491A5 (enExample) 2014-07-31
JP6120769B2 true JP6120769B2 (ja) 2017-04-26

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ID=44246475

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JP2013513709A Active JP6120769B2 (ja) 2010-06-12 2011-06-10 抗菌ペプチド改変体及びそれをコードするポリヌクレオチド

Country Status (11)

Country Link
US (3) US8835604B2 (enExample)
EP (1) EP2580235B1 (enExample)
JP (1) JP6120769B2 (enExample)
CN (1) CN103068840B (enExample)
AR (1) AR081866A1 (enExample)
BR (1) BR112012031049A2 (enExample)
DK (1) DK2580235T3 (enExample)
ES (1) ES2699734T3 (enExample)
RU (1) RU2611173C2 (enExample)
TW (1) TWI654933B (enExample)
WO (1) WO2011154525A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007068735A1 (en) * 2005-12-14 2007-06-21 Novozymes A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
KR20160144071A (ko) 2015-06-08 2016-12-16 이주호 토출 작동 중 역방향 유입이 방지되는 팬 보조장치
CN107188944B (zh) * 2017-06-08 2020-07-07 中国农业科学院饲料研究所 海蚯蚓抗菌肽nz17074衍生肽n6及其应用
CN107266547A (zh) * 2017-06-26 2017-10-20 北京生泰云科技有限公司 海蚯蚓抗菌肽nz17074衍生肽n2及其应用
JP7550653B2 (ja) 2018-06-06 2024-09-13 シングロン エスエー 抗菌ぺプチドの遺伝子操作
RU2721273C1 (ru) * 2019-04-22 2020-05-18 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Пептид никомицин из морского кольчатого червя nicomache minor, обладающий антимикробным и противоопухолевым действием.
CN110754400B (zh) * 2019-10-28 2022-04-26 长江大学 一种提高黄鳝苗种人工孵化率的方法
EP4198045A1 (en) * 2021-12-16 2023-06-21 Université de Lille Antimicrobial peptides, variants and chemical analogues thereof and their uses

Family Cites Families (16)

* Cited by examiner, † Cited by third party
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DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
PT97110B (pt) 1990-03-23 1998-11-30 Gist Brocades Nv Processo para catalisar reaccoes acelaraveis por enzimas, mediante adicao ao meio reaccional de sementes de plantas transgenicas e para obtencao das referidas sementes
US6395966B1 (en) 1990-08-09 2002-05-28 Dekalb Genetics Corp. Fertile transgenic maize plants containing a gene encoding the pat protein
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE4343591A1 (de) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
CA2191718A1 (en) 1994-06-03 1995-12-14 Randy M. Berka Phosphonyldipeptides useful in the treatment of cardiovascular diseases
WO1996000787A1 (en) 1994-06-30 1996-01-11 Novo Nordisk Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein
WO2000024883A1 (en) 1998-10-26 2000-05-04 Novozymes A/S Constructing and screening a dna library of interest in filamentous fungal cells
CN100532561C (zh) 1999-03-22 2009-08-26 诺沃奇梅兹有限公司 新的葡糖淀粉酶及编码它的核酸序列
US7151204B2 (en) 2001-01-09 2006-12-19 Monsanto Technology Llc Maize chloroplast aldolase promoter compositions and methods for use thereof
WO2003012036A2 (en) 2001-07-27 2003-02-13 The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services Systems for in vivo site-directed mutagenesis using oligonucleotides
EA012569B1 (ru) * 2004-02-24 2009-10-30 Коммонвелт Сайентифик Энд Индастриал Рисёч Организейшн Пептид насекомых, обладающий противогрибковой и/или антибактериальной активностью, и способы его применения
AR052947A1 (es) * 2005-03-18 2007-04-11 Novozymes As Polipeptidos que tienen actividad antimicrobiana y polinucleotidos que codifican para los mismos
EP1922333B1 (en) 2005-08-26 2010-03-31 Novozymes Adenium Biotech A/S Polypeptides having antimicrobial activity and polynucleotides encoding same

Also Published As

Publication number Publication date
CN103068840A (zh) 2013-04-24
AR081866A1 (es) 2012-10-24
DK2580235T3 (en) 2019-01-28
RU2611173C2 (ru) 2017-02-21
US8835604B2 (en) 2014-09-16
TW201206353A (en) 2012-02-16
WO2011154525A1 (en) 2011-12-15
TWI654933B (zh) 2019-04-01
US20150031601A1 (en) 2015-01-29
RU2012148781A (ru) 2014-07-20
JP2013531491A (ja) 2013-08-08
EP2580235B1 (en) 2018-10-17
US20160158317A1 (en) 2016-06-09
BR112012031049A2 (pt) 2017-06-20
EP2580235A1 (en) 2013-04-17
CN103068840B (zh) 2016-11-16
US20110306750A1 (en) 2011-12-15
ES2699734T3 (es) 2019-02-12

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