JP2013136622A5 - - Google Patents
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- Publication number
- JP2013136622A5 JP2013136622A5 JP2013043836A JP2013043836A JP2013136622A5 JP 2013136622 A5 JP2013136622 A5 JP 2013136622A5 JP 2013043836 A JP2013043836 A JP 2013043836A JP 2013043836 A JP2013043836 A JP 2013043836A JP 2013136622 A5 JP2013136622 A5 JP 2013136622A5
- Authority
- JP
- Japan
- Prior art keywords
- lymphangiogenesis
- acid sequence
- amino acid
- growth factor
- hepatocyte growth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 102000003745 Hepatocyte Growth Factor Human genes 0.000 claims 5
- 108090000100 Hepatocyte Growth Factor Proteins 0.000 claims 5
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 238000009472 formulation Methods 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 230000035168 lymphangiogenesis Effects 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 2
- 238000013270 controlled release Methods 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000002502 liposome Substances 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 206010048768 Dermatosis Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 241001303601 Rosacea Species 0.000 claims 1
- 239000006185 dispersion Substances 0.000 claims 1
- 239000006193 liquid solution Substances 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 201000004700 rosacea Diseases 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 239000012049 topical pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66746305P | 2005-03-31 | 2005-03-31 | |
| US60/667,463 | 2005-03-31 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008504520A Division JP5313660B2 (ja) | 2005-03-31 | 2006-03-30 | Ｈｇｆ／ｈｇｆｒ活性の観察と調節 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013149577A Division JP5722960B2 (ja) | 2005-03-31 | 2013-07-18 | Ｈｇｆ／ｈｇｆｒ活性の観察と調節 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013136622A JP2013136622A (ja) | 2013-07-11 |
| JP2013136622A5 true JP2013136622A5 (enExample) | 2013-09-26 |
| JP5801835B2 JP5801835B2 (ja) | 2015-10-28 |
Family
ID=36638370
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008504520A Expired - Fee Related JP5313660B2 (ja) | 2005-03-31 | 2006-03-30 | Ｈｇｆ／ｈｇｆｒ活性の観察と調節 |
| JP2010109852A Expired - Fee Related JP4664441B2 (ja) | 2005-03-31 | 2010-05-12 | Ｈｇｆ／ｈｇｆｒ活性の観察と調節 |
| JP2012090431A Pending JP2012149087A (ja) | 2005-03-31 | 2012-04-11 | Ｈｇｆ／ｈｇｆｒ活性の観察と調節 |
| JP2013043836A Expired - Fee Related JP5801835B2 (ja) | 2005-03-31 | 2013-03-06 | Ｈｇｆ／ｈｇｆｒ活性の観察と調節 |
| JP2013149577A Expired - Fee Related JP5722960B2 (ja) | 2005-03-31 | 2013-07-18 | Ｈｇｆ／ｈｇｆｒ活性の観察と調節 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008504520A Expired - Fee Related JP5313660B2 (ja) | 2005-03-31 | 2006-03-30 | Ｈｇｆ／ｈｇｆｒ活性の観察と調節 |
| JP2010109852A Expired - Fee Related JP4664441B2 (ja) | 2005-03-31 | 2010-05-12 | Ｈｇｆ／ｈｇｆｒ活性の観察と調節 |
| JP2012090431A Pending JP2012149087A (ja) | 2005-03-31 | 2012-04-11 | Ｈｇｆ／ｈｇｆｒ活性の観察と調節 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013149577A Expired - Fee Related JP5722960B2 (ja) | 2005-03-31 | 2013-07-18 | Ｈｇｆ／ｈｇｆｒ活性の観察と調節 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20070010443A1 (enExample) |
| EP (2) | EP2674165B1 (enExample) |
| JP (5) | JP5313660B2 (enExample) |
| KR (3) | KR20130114763A (enExample) |
| CN (2) | CN101189023B (enExample) |
| DK (1) | DK1863519T3 (enExample) |
| ES (1) | ES2440953T3 (enExample) |
| PL (1) | PL1863519T3 (enExample) |
| TW (1) | TWI362940B (enExample) |
| WO (1) | WO2006105511A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005107461A2 (en) * | 2004-04-07 | 2005-11-17 | The General Hospital Corporation | Modulating lymphatic function |
| SI1846406T1 (sl) | 2005-02-09 | 2011-02-28 | Arqule Inc | Maleimidni derivati, farmacevtski sestavki in postopki za zdravljenje raka |
| KR20130114763A (ko) * | 2005-03-31 | 2013-10-18 | 더 제너럴 하스피탈 코포레이션 | Ｈｇｆ／ｈｇｆｒ 활성의 모니터링 및 조정 |
| WO2007013603A1 (ja) | 2005-07-28 | 2007-02-01 | Anges Mg, Inc. | リンパ管新生促進剤 |
| EP1952826A4 (en) * | 2005-10-24 | 2011-05-18 | Fujifilm Ri Pharma Co Ltd | DIAGNOSTIC AGENT AND THERAPEUTIC AGENT FOR DISEASES RELATED TO THE HEPATOCYTE GROWTH FACTOR RECEPTOR |
| EP2173724B1 (en) | 2007-06-22 | 2012-12-05 | ArQule, Inc. | Quinazolinone compounds and methods of use thereof |
| WO2009002807A2 (en) | 2007-06-22 | 2008-12-31 | Arqule, Inc. | Indolyl pyrrolidines for the treatment of cancer |
| CN101801961B (zh) | 2007-06-22 | 2014-09-24 | 艾科尔公司 | 吡咯烷酮、吡咯烷-2,5-二酮、吡咯烷和硫代琥珀酰亚胺衍生物、组合物以及治疗癌症的方法 |
| EP2236605B1 (en) * | 2007-12-28 | 2016-06-08 | The Chemo-Sero-Therapeutic Research Institute | Human anti-alpha 9 integrin antibody |
| US8940708B2 (en) * | 2009-12-23 | 2015-01-27 | Curna, Inc. | Treatment of hepatocyte growth factor (HGF) related diseases by inhibition of natural antisense transcript to HGF |
| KR101814571B1 (ko) | 2010-03-10 | 2018-01-04 | 젠맵 에이/에스 | Ｃ―ｍｅｔ에 대한 모노클로날 항체 |
| CN105209483B (zh) * | 2013-05-31 | 2021-07-27 | 分子组合公司 | 与肝细胞生长因子结合的设计锚蛋白重复蛋白 |
| KR20170136536A (ko) | 2015-03-16 | 2017-12-11 | 셀덱스 쎄라퓨틱스, 인크. | 항-met 항체 및 그 사용 방법 |
| KR101843248B1 (ko) * | 2015-03-17 | 2018-03-29 | 고려대학교 세종산학협력단 | 흉선 기질 림프단백질 매개 신호전달을 제어하는 펩타이드 유도체 및 이를 포함하는 알러지 및 천식 질환 예방 및 치료용 약학 조성물 |
| WO2017019454A2 (en) | 2015-07-28 | 2017-02-02 | Musc Foundation For Research Development | Identification of novel anti-fibrotic peptide in c-terminal region of the met receptor tyrosine kinase |
| CN109535243B (zh) * | 2019-01-07 | 2019-09-24 | 北京诺思兰德生物技术股份有限公司 | 人肝细胞生长因子突变体及其应用 |
| CN114292899B (zh) * | 2022-01-08 | 2024-03-26 | 安徽医科大学第一附属医院 | 一种肝细胞生长因子检测及信号增敏探针、引物对及其应用 |
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| EP1661578B1 (en) * | 2003-09-03 | 2018-03-14 | Toshikazu Nakamura | Skin ulcer preventive curative agent containing human recombinant hgf |
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| KR20130114763A (ko) * | 2005-03-31 | 2013-10-18 | 더 제너럴 하스피탈 코포레이션 | Ｈｇｆ／ｈｇｆｒ 활성의 모니터링 및 조정 |
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| JP2016031772A (ja) | 2014-07-30 | 2016-03-07 | 株式会社日立ハイテクファインシステムズ | 熱アシスト磁気ヘッド素子の検査方法及びその装置 |
-
2006
- 2006-03-30 KR KR1020137019978A patent/KR20130114763A/ko not_active Abandoned
- 2006-03-30 KR KR1020077024730A patent/KR20070119710A/ko not_active Withdrawn
- 2006-03-30 CN CN2006800191873A patent/CN101189023B/zh not_active Expired - Fee Related
- 2006-03-30 PL PL06749190T patent/PL1863519T3/pl unknown
- 2006-03-30 ES ES06749190.2T patent/ES2440953T3/es active Active
- 2006-03-30 EP EP13172330.6A patent/EP2674165B1/en not_active Not-in-force
- 2006-03-30 JP JP2008504520A patent/JP5313660B2/ja not_active Expired - Fee Related
- 2006-03-30 CN CN201210536271.XA patent/CN102989012B/zh not_active Expired - Fee Related
- 2006-03-30 WO PCT/US2006/012389 patent/WO2006105511A1/en not_active Ceased
- 2006-03-30 EP EP06749190.2A patent/EP1863519B1/en not_active Not-in-force
- 2006-03-30 KR KR1020147011245A patent/KR20140068234A/ko not_active Ceased
- 2006-03-30 TW TW095111167A patent/TWI362940B/zh not_active IP Right Cessation
- 2006-03-30 DK DK06749190.2T patent/DK1863519T3/da active
- 2006-03-31 US US11/394,422 patent/US20070010443A1/en not_active Abandoned
-
2010
- 2010-05-12 JP JP2010109852A patent/JP4664441B2/ja not_active Expired - Fee Related
- 2010-05-20 US US12/784,272 patent/US20100227821A1/en not_active Abandoned
-
2012
- 2012-04-11 JP JP2012090431A patent/JP2012149087A/ja active Pending
- 2012-09-07 US US13/606,490 patent/US8865673B2/en active Active
-
2013
- 2013-03-06 JP JP2013043836A patent/JP5801835B2/ja not_active Expired - Fee Related
- 2013-07-18 JP JP2013149577A patent/JP5722960B2/ja not_active Expired - Fee Related
-
2014
- 2014-10-07 US US14/508,576 patent/US20150030611A1/en not_active Abandoned
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