UA117103C2 - Сполука, яка має активність агоніста глюкагону - Google Patents

Сполука, яка має активність агоніста глюкагону

Info

Publication number
UA117103C2
UA117103C2 UAA201500436A UAA201500436A UA117103C2 UA 117103 C2 UA117103 C2 UA 117103C2 UA A201500436 A UAA201500436 A UA A201500436A UA A201500436 A UAA201500436 A UA A201500436A UA 117103 C2 UA117103 C2 UA 117103C2
Authority
UA
Ukraine
Prior art keywords
compound
agonist activity
glucagon agonist
relates
hypoglycemia
Prior art date
Application number
UAA201500436A
Other languages
English (en)
Inventor
Дітте Рібер
Лізе Гіем
Original Assignee
Зіленд Фарма А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Зіленд Фарма А/С filed Critical Зіленд Фарма А/С
Publication of UA117103C2 publication Critical patent/UA117103C2/uk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Винахід стосується сполуки або її фармацевтично прийнятної солі або сольвату, яка має активність агоніста глюкагону. Винахід також стосується конструкції нуклеїнової кислоти, вектора, клітини-хазяїна, фармацевтичної композиції, яка містить дану сполуку, способу лікування захворювання або стану у суб’єкта, який потребує цього, та застосування сполуки при отриманні лікарського препарату для лікування гіпоглікемії.
UAA201500436A 2012-07-23 2013-07-23 Сполука, яка має активність агоніста глюкагону UA117103C2 (uk)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261674706P 2012-07-23 2012-07-23
US201361785611P 2013-03-14 2013-03-14
DKPA201300360 2013-06-14
PCT/EP2013/065519 WO2014016300A1 (en) 2012-07-23 2013-07-23 Glucagon analogues

Publications (1)

Publication Number Publication Date
UA117103C2 true UA117103C2 (uk) 2018-06-25

Family

ID=49996630

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201500436A UA117103C2 (uk) 2012-07-23 2013-07-23 Сполука, яка має активність агоніста глюкагону

Country Status (27)

Country Link
US (3) US10442847B2 (uk)
EP (1) EP2875043B1 (uk)
JP (3) JP6534927B2 (uk)
KR (1) KR102129235B1 (uk)
CN (2) CN109456400A (uk)
AR (1) AR091866A1 (uk)
AU (1) AU2013295035B2 (uk)
BR (1) BR112015001451B1 (uk)
CA (1) CA2878991C (uk)
DK (1) DK2875043T3 (uk)
EA (1) EA033399B1 (uk)
ES (1) ES2620111T3 (uk)
FI (1) FIC20240034I1 (uk)
FR (1) FR24C1043I2 (uk)
IL (1) IL236554B (uk)
IN (1) IN2015DN00544A (uk)
MX (1) MX356957B (uk)
MY (1) MY170671A (uk)
NL (1) NL301294I2 (uk)
NZ (1) NZ704043A (uk)
PH (1) PH12015500115B1 (uk)
PL (1) PL2875043T3 (uk)
SG (1) SG11201500375PA (uk)
TW (1) TWI642682B (uk)
UA (1) UA117103C2 (uk)
WO (1) WO2014016300A1 (uk)
ZA (1) ZA201702364B (uk)

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JP2020527396A (ja) 2017-07-14 2020-09-10 ゼリス ファーマシューティカルズ インコーポレイテッド 先天性高インスリン症を処置する方法
KR20200134213A (ko) * 2018-01-23 2020-12-01 엑스에리스 파머수티클스, 인크. 소 용량의 안정한 글루카곤을 사용한 베리아트릭 후 저혈당증의 치료
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