EP0763103A4 - Gene delivery vector using plasmid dna packaged into an adenovirus and a packaging cell line - Google Patents

Gene delivery vector using plasmid dna packaged into an adenovirus and a packaging cell line

Info

Publication number
EP0763103A4
EP0763103A4 EP95917176A EP95917176A EP0763103A4 EP 0763103 A4 EP0763103 A4 EP 0763103A4 EP 95917176 A EP95917176 A EP 95917176A EP 95917176 A EP95917176 A EP 95917176A EP 0763103 A4 EP0763103 A4 EP 0763103A4
Authority
EP
European Patent Office
Prior art keywords
adenovirus
cell line
plasmid dna
gene delivery
packaging cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95917176A
Other languages
German (de)
French (fr)
Other versions
EP0763103A1 (en
Inventor
Gary J Nabel
Michael J Imperiale
Takeshi Ohno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan
Original Assignee
University of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Michigan filed Critical University of Michigan
Publication of EP0763103A1 publication Critical patent/EP0763103A1/en
Publication of EP0763103A4 publication Critical patent/EP0763103A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP95917176A 1994-04-28 1995-04-25 Gene delivery vector using plasmid dna packaged into an adenovirus and a packaging cell line Withdrawn EP0763103A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US234990 1988-08-22
US23499094A 1994-04-28 1994-04-28
PCT/US1995/005174 WO1995029993A1 (en) 1994-04-28 1995-04-25 Gene delivery vector using plasmid dna packaged into an adenovirus and a packaging cell line

Publications (2)

Publication Number Publication Date
EP0763103A1 EP0763103A1 (en) 1997-03-19
EP0763103A4 true EP0763103A4 (en) 1998-07-15

Family

ID=22883604

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95917176A Withdrawn EP0763103A4 (en) 1994-04-28 1995-04-25 Gene delivery vector using plasmid dna packaged into an adenovirus and a packaging cell line

Country Status (4)

Country Link
EP (1) EP0763103A4 (en)
JP (1) JPH10507061A (en)
CA (1) CA2189067A1 (en)
WO (1) WO1995029993A1 (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020164782A1 (en) 1999-02-10 2002-11-07 Gregory Richard J. Adenovirus vectors for gene therapy
US5670488A (en) * 1992-12-03 1997-09-23 Genzyme Corporation Adenovirus vector for gene therapy
US7252989B1 (en) 1994-04-04 2007-08-07 Board Of Regents, The University Of Texas System Adenovirus supervector system
DK0787200T3 (en) * 1994-10-28 2005-08-15 Univ Pennsylvania Improved adenovirus and methods for its use
CA2218610A1 (en) * 1995-04-17 1996-10-24 Board Of Regents, The University Of Texas System An adenovirus helper-virus system
EP0888086B1 (en) 1996-02-15 2005-07-27 Biosense Webster, Inc. Excavation probe
WO1997032481A1 (en) * 1996-03-07 1997-09-12 The Regents Of The University Of California Helper-free, totally defective adenovirus for gene therapy
US6544523B1 (en) 1996-11-13 2003-04-08 Chiron Corporation Mutant forms of Fas ligand and uses thereof
CA2308606A1 (en) 1997-11-06 1999-05-20 Chiron S.P.A. Neisserial antigens
EP1034266A1 (en) * 1997-11-25 2000-09-13 Princeton University Method for preparing adenovirus vectors, vectors so prepared, and uses thereof
AU759573B2 (en) 1997-12-23 2003-04-17 Crucell Holland B.V. Adeno-associated virus and adenovirus chimeric recombinant viruses useful for the integration of foreign genetic information into the chromosomal DNA of target cells
AU1979599A (en) 1998-01-14 1999-08-02 Chiron S.P.A. (neisseria meningitidis) antigens
ES2293473T3 (en) 1998-02-05 2008-03-16 Biosense Webster, Inc. INTRACARDIAC ADMINISTRATION OF FARMACO.
BR9910089A (en) 1998-05-01 2004-06-08 Chiron Corp Compositions and antigens of neisseria meningitidis
US6113913A (en) 1998-06-26 2000-09-05 Genvec, Inc. Recombinant adenovirus
GB9817660D0 (en) 1998-08-13 1998-10-07 Angeletti P Ist Richerche Bio Adenoviral vectors encoding erythropoietin and their use in gene therapy
RU2245366C2 (en) 1999-04-30 2005-01-27 Чирон С.Р.Л. Neisseria antigen, nucleic acid encoding its, their applying
GB9911683D0 (en) 1999-05-19 1999-07-21 Chiron Spa Antigenic peptides
GB9916529D0 (en) 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
EP2275552B1 (en) 1999-10-29 2015-09-09 GlaxoSmithKline Biologicals SA Neisserial antigenic peptides
PT2289545T (en) 2000-01-17 2016-09-06 Glaxosmithkline Biologicals Sa Supplemented omv vaccine against meningococcus
MXPA03003690A (en) 2000-10-27 2004-05-05 Chiron Spa Nucleic acids and proteins from streptococcus groups a b.
GB0107661D0 (en) 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
GB0107658D0 (en) 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
ES2312649T3 (en) 2001-12-12 2009-03-01 Novartis Vaccines And Diagnostics S.R.L. IMMUNIZATION AGAINST CHLAMYDIA TRACHOMATIS.
GB0308198D0 (en) 2003-04-09 2003-05-14 Chiron Srl ADP-ribosylating bacterial toxin
PT1736541E (en) 2004-03-29 2013-01-31 Galpharma Co Ltd Novel modified galectin 9 protein and use thereof
CN101094688B (en) 2004-09-13 2013-05-01 建新公司 Multimeric constructs
AR059089A1 (en) 2006-01-20 2008-03-12 Genzyme Corp INTRAVENTRICULAR ADMINISTRATION OF AN ENZYME FOR LISOSOMAL STORAGE DISEASES
PL1988823T3 (en) 2006-02-09 2019-01-31 Genzyme Corporation Slow intraventricular delivery
US20110206692A1 (en) 2006-06-09 2011-08-25 Novartis Ag Conformers of bacterial adhesins
WO2013119880A1 (en) 2012-02-07 2013-08-15 Global Bio Therapeutics Usa, Inc. Compartmentalized method of nucleic acid delivery and compositions and uses thereof
US11364032B2 (en) 2013-08-08 2022-06-21 Global Bio Therapeutics, Inc. Clamp device for minimally invasive procedures and uses thereof
CN118139655A (en) 2021-08-13 2024-06-04 特里奥万斯控股公司 Skin substitute compositions and methods of making and using the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994028152A1 (en) * 1993-05-28 1994-12-08 Transgene S.A. Defective adenoviruses and corresponding complementation lines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2115742A1 (en) * 1991-08-20 1993-03-04 Ronald G. Crystal Adenovirus mediated transfer of genes to the gastrointestinal tract
WO1994008026A1 (en) * 1992-09-25 1994-04-14 Rhone-Poulenc Rorer S.A. Adenovirus vectors for the transfer of foreign genes into cells of the central nervous system, particularly in brain

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994028152A1 (en) * 1993-05-28 1994-12-08 Transgene S.A. Defective adenoviruses and corresponding complementation lines

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GRABLE AND HEARING: "cis and trans Requirements for the selective packaging of Adenovirus type 5 DNA", JOURNAL OF VIROLOGY, vol. 66, no. 2, February 1992 (1992-02-01), AMERICAN SOCIETY FOR MICROBIOLOGY US, pages 723 - 731, XP002012398 *
MASTRANGELI ET AL.: "Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 91, January 1993 (1993-01-01), pages 225 - 234, XP000616634 *
ROSENFELD ET AL.: "In vivo transfer of the human Cystic Fibrosis Transmembrane Conductance Regulator gene to the airway epithelium", CELL, vol. 68, no. 1, 10 January 1992 (1992-01-10), NA US, pages 143 - 155, XP002064228 *
See also references of WO9529993A1 *
STRATFORD-PERRICAUDET AND PERRICAUDET: "Gene transfer into animals: the promise of adenovirus", HUMAN GENE TRANSFER (COHEN-HAGUENAUER AND BOIRON EDS.), vol. 219, 1991, pages 51 - 61, XP002064227 *

Also Published As

Publication number Publication date
EP0763103A1 (en) 1997-03-19
CA2189067A1 (en) 1995-11-09
JPH10507061A (en) 1998-07-14
WO1995029993A1 (en) 1995-11-09

Similar Documents

Publication Publication Date Title
EP0763103A4 (en) Gene delivery vector using plasmid dna packaged into an adenovirus and a packaging cell line
HU9700428D0 (en) Targetcell-specific vectors for inserting genes into cells, pharmaceuticals comprising such vectors and their use
AU7097494A (en) Envelope fusion vectors for use in gene delivery
GB2330575B (en) Blister pack
EP0808169A4 (en) Programmed cell death genes and proteins
AU7595498A (en) Medicament dispensing cell
GB2312421B (en) Blister pack
KR970002669B1 (en) Reagents and methods for modulating gene expression through rna mimicry
ZA953466B (en) Blister package containing gripping means
EP1005561A4 (en) Vector and viral vectors, and packaging cell lines for propagating same
GB2297965B (en) Flat Pack Container
GB0000453D0 (en) Handling ATM multicast cells
PL342687A1 (en) Container and transfer case for dispensing paper articles
AU5871498A (en) Non-resealable bottle and container therefor
HUP9801214A3 (en) Recombinant viruses expressing lecithin-cholesterol acyltransferase, and uses thereof in gene therapy
TW489813U (en) Loading machine, container and transportation device
GB9614699D0 (en) Hybrid herpes virus-based vector for gene delivery and expression
GB9407786D0 (en) Container for packaging and display
IL118783A0 (en) An assembly and container for dispensing medicaments
GB9624925D0 (en) Newspaper and magazine protective carrying pouch
GB2287448B (en) Container filling and pack forming apparatus
GB9618228D0 (en) Improved apparatus for containing and dispensing products in separate packs
EP0693425A3 (en) Handling partly completed containers
ZA961112B (en) Blister pack
EP0759938A4 (en) Neurogenic differentiation (neurod) genes and proteins

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19961115

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 19980602

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 20010726

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20011205