FR2981661B1 - Procede de preparation du facteur h humain - Google Patents

Procede de preparation du facteur h humain

Info

Publication number
FR2981661B1
FR2981661B1 FR1159686A FR1159686A FR2981661B1 FR 2981661 B1 FR2981661 B1 FR 2981661B1 FR 1159686 A FR1159686 A FR 1159686A FR 1159686 A FR1159686 A FR 1159686A FR 2981661 B1 FR2981661 B1 FR 2981661B1
Authority
FR
France
Prior art keywords
preparing
human factor
factor
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1159686A
Other languages
English (en)
Other versions
FR2981661A1 (fr
Inventor
Toufik Abache
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LFB SA
Original Assignee
LFB Biotechnologies SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LFB Biotechnologies SAS filed Critical LFB Biotechnologies SAS
Priority to FR1159686A priority Critical patent/FR2981661B1/fr
Priority to EP12794376.9A priority patent/EP2771354A1/fr
Priority to JP2014537698A priority patent/JP2014532401A/ja
Priority to CA2850295A priority patent/CA2850295A1/fr
Priority to US14/353,595 priority patent/US20140271603A1/en
Priority to PCT/FR2012/052461 priority patent/WO2013060995A1/fr
Publication of FR2981661A1 publication Critical patent/FR2981661A1/fr
Application granted granted Critical
Publication of FR2981661B1 publication Critical patent/FR2981661B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/472Complement proteins, e.g. anaphylatoxin, C3a, C5a
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/22Vectors comprising a coding region that has been codon optimised for expression in a respective host

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR1159686A 2011-10-25 2011-10-25 Procede de preparation du facteur h humain Expired - Fee Related FR2981661B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR1159686A FR2981661B1 (fr) 2011-10-25 2011-10-25 Procede de preparation du facteur h humain
EP12794376.9A EP2771354A1 (fr) 2011-10-25 2012-10-25 Procede de preparation du facteur h humain
JP2014537698A JP2014532401A (ja) 2011-10-25 2012-10-25 ヒトh因子の製造方法
CA2850295A CA2850295A1 (fr) 2011-10-25 2012-10-25 Procede de preparation du facteur h humain
US14/353,595 US20140271603A1 (en) 2011-10-25 2012-10-25 Method for preparing human factor h
PCT/FR2012/052461 WO2013060995A1 (fr) 2011-10-25 2012-10-25 Procede de preparation du facteur h humain

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1159686A FR2981661B1 (fr) 2011-10-25 2011-10-25 Procede de preparation du facteur h humain

Publications (2)

Publication Number Publication Date
FR2981661A1 FR2981661A1 (fr) 2013-04-26
FR2981661B1 true FR2981661B1 (fr) 2015-06-19

Family

ID=47263414

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1159686A Expired - Fee Related FR2981661B1 (fr) 2011-10-25 2011-10-25 Procede de preparation du facteur h humain

Country Status (6)

Country Link
US (1) US20140271603A1 (fr)
EP (1) EP2771354A1 (fr)
JP (1) JP2014532401A (fr)
CA (1) CA2850295A1 (fr)
FR (1) FR2981661B1 (fr)
WO (1) WO2013060995A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201821089D0 (en) * 2018-12-21 2019-02-06 Gyroscope Therapeutics Ltd Codon-optimised complement factor I

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090118163A1 (en) * 2005-09-19 2009-05-07 Peter Gronski Factor H for the Treatment of Chronic Nephropathies and Production thereof
FR2894145B1 (fr) * 2005-12-07 2008-10-17 Lab Francais Du Fractionnement Utilisation de facteur h du complement a titre de medicament
WO2008045548A2 (fr) * 2006-10-12 2008-04-17 Copernicus Therapeutics Inc. Cftr à optimisation par codon
WO2008135963A2 (fr) * 2007-05-02 2008-11-13 Hemogem Inc. Fibrinogène pour traitement d'hémorragies traumatiques et de pathologies plaquettaires
JP5819725B2 (ja) * 2008-07-09 2015-11-24 プロフィブリックス ビーブイ 組換えフィブリノゲン
FR2952640B1 (fr) * 2009-11-16 2012-12-07 Lab Francais Du Fractionnement Procede de fabrication d'une preparation de facteur h
GB0922659D0 (en) * 2009-12-24 2010-02-10 Univ Edinburgh Factor H
FR2957598B1 (fr) * 2010-03-17 2015-12-04 Lfb Biotechnologies Nouveau peptide signal, et son utilisation pour la production de proteines recombinantes

Also Published As

Publication number Publication date
US20140271603A1 (en) 2014-09-18
FR2981661A1 (fr) 2013-04-26
WO2013060995A1 (fr) 2013-05-02
CA2850295A1 (fr) 2013-05-02
JP2014532401A (ja) 2014-12-08
EP2771354A1 (fr) 2014-09-03

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Legal Events

Date Code Title Description
TP Transmission of property

Owner name: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES , FR

Effective date: 20130820

PLFP Fee payment

Year of fee payment: 5

PLFP Fee payment

Year of fee payment: 6

PLFP Fee payment

Year of fee payment: 7

PLFP Fee payment

Year of fee payment: 8

ST Notification of lapse

Effective date: 20200914