JP2019519221A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019519221A5 JP2019519221A5 JP2018560974A JP2018560974A JP2019519221A5 JP 2019519221 A5 JP2019519221 A5 JP 2019519221A5 JP 2018560974 A JP2018560974 A JP 2018560974A JP 2018560974 A JP2018560974 A JP 2018560974A JP 2019519221 A5 JP2019519221 A5 JP 2019519221A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- appendix
- protein
- acid sequence
- viral vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021194601A JP7315284B2 (ja) | 2016-05-20 | 2021-11-30 | 加齢関連疾患及び症状の遺伝子治療法 |
| JP2023044658A JP2023078338A (ja) | 2016-05-20 | 2023-03-20 | 加齢関連疾患及び症状の遺伝子治療法 |
| JP2025028446A JP2025078652A (ja) | 2016-05-20 | 2025-02-25 | 加齢関連疾患及び症状の遺伝子治療法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662339182P | 2016-05-20 | 2016-05-20 | |
| US62/339,182 | 2016-05-20 | ||
| US201662421665P | 2016-11-14 | 2016-11-14 | |
| US62/421,665 | 2016-11-14 | ||
| PCT/US2017/033815 WO2017201527A2 (en) | 2016-05-20 | 2017-05-22 | Gene therapy methods for age-related diseases and conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021194601A Division JP7315284B2 (ja) | 2016-05-20 | 2021-11-30 | 加齢関連疾患及び症状の遺伝子治療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019519221A JP2019519221A (ja) | 2019-07-11 |
| JP2019519221A5 true JP2019519221A5 (enExample) | 2020-08-27 |
| JP7632835B2 JP7632835B2 (ja) | 2025-02-19 |
Family
ID=60326179
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018560974A Active JP7632835B2 (ja) | 2016-05-20 | 2017-05-22 | 加齢関連疾患及び症状の遺伝子治療法 |
| JP2021194601A Active JP7315284B2 (ja) | 2016-05-20 | 2021-11-30 | 加齢関連疾患及び症状の遺伝子治療法 |
| JP2023044658A Pending JP2023078338A (ja) | 2016-05-20 | 2023-03-20 | 加齢関連疾患及び症状の遺伝子治療法 |
| JP2025028446A Pending JP2025078652A (ja) | 2016-05-20 | 2025-02-25 | 加齢関連疾患及び症状の遺伝子治療法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021194601A Active JP7315284B2 (ja) | 2016-05-20 | 2021-11-30 | 加齢関連疾患及び症状の遺伝子治療法 |
| JP2023044658A Pending JP2023078338A (ja) | 2016-05-20 | 2023-03-20 | 加齢関連疾患及び症状の遺伝子治療法 |
| JP2025028446A Pending JP2025078652A (ja) | 2016-05-20 | 2025-02-25 | 加齢関連疾患及び症状の遺伝子治療法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US12281154B2 (enExample) |
| EP (1) | EP3458585A4 (enExample) |
| JP (4) | JP7632835B2 (enExample) |
| CN (2) | CN109844124B (enExample) |
| AU (2) | AU2017268469C1 (enExample) |
| BR (1) | BR112018073861A2 (enExample) |
| CA (1) | CA3025020A1 (enExample) |
| MX (2) | MX2018014256A (enExample) |
| WO (1) | WO2017201527A2 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11208443B2 (en) * | 2017-02-14 | 2021-12-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | NAF-1 derived peptides and uses thereof |
| EP4653536A2 (en) * | 2017-03-17 | 2025-11-26 | Adverum Biotechnologies, Inc. | Compositions and methods for enhanced gene expression |
| JP7778469B2 (ja) * | 2017-05-24 | 2025-12-02 | ウニベルシダッド アウトノマ デ バルセロナ | 線維芽細胞増殖因子２１（ｆｇｆ２１）コーディング配列を含むウイルス発現コンストラクト |
| CN119390821A (zh) | 2017-08-15 | 2025-02-07 | 伊兰科美国公司 | 兽药用IgG Fc变体 |
| US11530433B2 (en) * | 2017-10-20 | 2022-12-20 | President And Fellows Of Harvard College | Artificial secretion peptides for heterologous protein production |
| US11807850B2 (en) | 2017-12-06 | 2023-11-07 | Klogenix Llc | Compositions and methods for modulating gene expression |
| CA3110290A1 (en) * | 2018-08-30 | 2020-03-05 | Research Institute At Nationwide Children's Hospital | Gene therapy for the treatment of galactosemia |
| BR112021006977A2 (pt) * | 2018-10-18 | 2021-07-27 | Kindred Biosciences, Inc. | variantes fc com ligação alterada a receptor fc neonatal (fcrn) para uso veterinário |
| US12134772B2 (en) | 2018-11-21 | 2024-11-05 | Advantage Therapeutics, Inc. | Increasing gene expression |
| CA3120923A1 (en) * | 2018-11-26 | 2020-06-04 | Universitat Autonoma De Barcelona | Fibroblast growth factor 21 (fgf21) gene therapy |
| US11505797B2 (en) | 2019-05-23 | 2022-11-22 | Christiana Care Health Services, Inc. | Gene knockout of variant NRF2 for treatment of cancer |
| US12203070B2 (en) | 2019-05-23 | 2025-01-21 | Christiana Care Gene Editing Institute, Inc. | Gene knockout of NRF2 for treatment of cancer |
| JP2022536692A (ja) | 2019-06-11 | 2022-08-18 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | 調節不全の血漿カリクレインによって媒介される疾患の治療のための抗体のアデノ随伴ウイルスベクター送達 |
| US10653731B1 (en) * | 2019-07-15 | 2020-05-19 | Vigene Biosciences Inc. | Recombinantly-modified adeno-associated virus (rAAV) having improved packaging efficiency |
| KR102281858B1 (ko) | 2019-09-11 | 2021-07-26 | 주식회사 쎌바이오텍 | 유산균 유래 p8 단백질의 발현 컨스트럭트를 포함하는 대장 질환의 치료 또는 예방용 조성물 |
| EP4028532A1 (en) * | 2019-09-13 | 2022-07-20 | Rutgers, the State University of New Jersey | Aav-compatible laminin-linker polymerization proteins |
| EP4048800A1 (en) | 2019-10-23 | 2022-08-31 | Shire Human Genetic Therapies, Inc. | Adeno-associated virus vectors based gene therapy for hereditary angioedema |
| CN110894508B (zh) * | 2019-10-31 | 2021-08-06 | 内蒙古大学 | 一种调控白色脂肪棕色化的基因Adra1a的应用 |
| CN115515645A (zh) * | 2019-12-05 | 2022-12-23 | 哈佛学院董事及会员团体 | 治疗骨关节炎的方法 |
| JP7588466B2 (ja) * | 2020-01-22 | 2024-11-22 | 旭化成メディカル株式会社 | パルボウイルスの生産方法 |
| EP4142758A4 (en) * | 2020-04-28 | 2025-02-26 | President and Fellows of Harvard College | High efficiency gene delivery system |
| JP2023526049A (ja) * | 2020-05-13 | 2023-06-20 | リソジェン | Ｇｍ１ガングリオシド－シスおよび他の障害を処置するための組成物および方法 |
| WO2021239815A1 (en) * | 2020-05-26 | 2021-12-02 | Universitat Autònoma De Barcelona | Fibroblast growth factor 21 (fgf21) gene therapy for central nervous system disorders |
| CN114181944B (zh) * | 2020-09-14 | 2023-10-03 | 中国科学院动物研究所 | 突变基因及构建短肢性侏儒症小型猪模型的方法和用途 |
| WO2022115739A2 (en) * | 2020-11-30 | 2022-06-02 | Cellular Longevity, Inc. | Lnp and liposome compositions for longevity in mammals and methods of using the same |
| CN116829595A (zh) | 2020-12-16 | 2023-09-29 | 武田药品工业株式会社 | 用于治疗由失调的血浆激肽释放酶介导的疾病的抗体的腺相关病毒载体递送 |
| KR102590276B1 (ko) * | 2021-01-04 | 2023-10-16 | 부산대학교 산학협력단 | 조직 특이적 발현을 위한 융합 프로모터 및 이의 용도 |
| CN113444730A (zh) * | 2021-03-17 | 2021-09-28 | 昆明市延安医院 | 一种原发性肝细胞klotho基因转导干细胞筛选构建方法 |
| CN113088531B (zh) * | 2021-03-25 | 2023-10-17 | 四川省药品检验研究院(四川省医疗器械检测中心) | 牛源性成分定量分析标准质粒、制备及检测方法及应用 |
| US20240124541A1 (en) * | 2021-04-12 | 2024-04-18 | University of Florida Research Foundation, Incorprated | Compositions and methods for treating obesity |
| JP2022169389A (ja) * | 2021-04-27 | 2022-11-09 | 国立大学法人北海道大学 | イヌＴＧＦ－β受容体ＩＩ |
| US20220401583A1 (en) * | 2021-06-16 | 2022-12-22 | BioViva USA, Inc. | Treatment of age-related cognitive decline using genetically modified viral vectors |
| US20230018934A1 (en) * | 2021-07-16 | 2023-01-19 | Genflow Biosciences Srl | Method of in vivo administration of the coding sequence of the sirt6 gene via adeno-associated virus |
| EP4408482A4 (en) * | 2021-09-29 | 2025-11-12 | Sirt6 Ltd | METHOD OF TREATING A DISEASE |
| CN114921480A (zh) * | 2022-06-09 | 2022-08-19 | 国科宁波生命与健康产业研究院 | 一种骨细胞Terc基因敲除小鼠模型的构建方法 |
| WO2024064785A2 (en) * | 2022-09-21 | 2024-03-28 | Rejuvenate Bio | Gene therapy methods for familial partial lipodystrophy |
| WO2024064796A2 (en) * | 2022-09-21 | 2024-03-28 | Rejuvenate Bio | Gene therapy methods for arrhythmogenic cardiomyopathy |
| EP4590693A2 (en) * | 2022-09-21 | 2025-07-30 | Rejuvenate Bio Inc | Gene therapy methods for treating mitral valve disease |
| CN116790610B (zh) * | 2023-05-18 | 2024-09-20 | 四川大学 | 一种治疗骨科疾病的基因及以aav为载体的基因治疗药物 |
| EP4566618A1 (en) * | 2023-12-06 | 2025-06-11 | ADvantage Therapeutics, Inc. | Nucleic acid encoding klotho for use in therapeutic and non-therapeutic methods for reducing body weight |
| WO2025109173A1 (en) | 2023-11-22 | 2025-05-30 | Advantage Therapeutics, Inc. | Nucleic acid encoding klotho for use in therapeutic and non-therapeutic methods for reducing body weight |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824655A (en) * | 1995-02-15 | 1998-10-20 | The University Of Utah | Anti-transforming growth factor-β gene therapy |
| TR199902878T2 (xx) | 1997-04-18 | 2000-02-21 | Biogen,Inc. | Tip II TGF-Beta Resept�r/�m�noglob�lin sabit b�l�m f�zyon proteinleri. |
| US7622300B2 (en) * | 1998-06-03 | 2009-11-24 | Kappes John C | Trans-lentiviral vector particles and transduction of eukaryotic cells therewith |
| US7419829B2 (en) * | 2000-10-06 | 2008-09-02 | Oxford Biomedica (Uk) Limited | Vector system |
| AU2003209226A1 (en) * | 2002-01-11 | 2003-07-30 | Michael Tennant | Adiponectin gene therapy |
| US8158589B2 (en) * | 2003-08-22 | 2012-04-17 | Proyecto Biomedicine Cima, S.L. | Peptides with the capacity to bind to transforming growth factor β1 (TGF-β1) |
| US7511056B2 (en) * | 2004-11-10 | 2009-03-31 | Eli Lilly And Company | TGF-β inhibitors |
| FR2879204B1 (fr) * | 2004-12-15 | 2007-02-16 | Lab Francais Du Fractionnement | Anticorps cytotoxique dirige contre les proliferations hematopoietiques lymphoides de type b. |
| ES2361269T3 (es) * | 2005-04-22 | 2011-06-15 | Eli Lilly And Company | Anticuerpos especificos de tgf beta 1. |
| DE102005061840A1 (de) * | 2005-12-23 | 2007-06-28 | Merck Patent Gmbh | Triazolderivate |
| US20070292922A1 (en) * | 2006-03-31 | 2007-12-20 | Cell Genesys, Inc. | Regulated expression of recombinant proteins from adeno-associated viral vectors |
| US20100190697A1 (en) * | 2006-09-13 | 2010-07-29 | The Trustees Of Columbia University In The City If | Undercarboxylated/uncarboxylated osteocalcin increases beta-cell proliferation, insulin secretion, insulin sensitivity, glucose tolerance and decreases fat mass |
| WO2008157367A1 (en) * | 2007-06-15 | 2008-12-24 | Genzyme Corporation | Fusion proteins containing two tgf-beta binding domains of tgf-beta type ii receptor |
| US8236557B2 (en) * | 2008-05-28 | 2012-08-07 | University Of Missouri-Columbia | Hybrid-AAV vectors to deliver large gene expression cassette |
| JO3096B1 (ar) * | 2008-11-07 | 2017-03-15 | Imclone Llc | الأجسام المضادة لمستقبل ii مضاد tgfb |
| IL300733B1 (en) * | 2010-03-05 | 2025-10-01 | Univ Johns Hopkins | Compositions and methods for antibodies and fusion proteins targeted for immune modulation |
| AR083445A1 (es) * | 2010-10-14 | 2013-02-27 | Univ Mie | siARN CONTRA LA FIBROSIS |
| DK2455104T3 (da) * | 2010-11-19 | 2013-10-14 | Universitaetsklinikum Freiburg | Biofunktionaliserede stimulusafhængige opløselige PEG-hydrogeler |
| EP2548570A1 (en) * | 2011-07-19 | 2013-01-23 | Sanofi | Pharmaceutical composition for treating a metabolic syndrome |
| EP2750695A2 (en) * | 2011-08-31 | 2014-07-09 | Amgen Inc. | Method of treating or ameliorating type 1 diabetes using fgf21 |
| TWI593708B (zh) * | 2011-09-26 | 2017-08-01 | 諾華公司 | 治療代謝病症之融合蛋白質 |
| CN103203027A (zh) * | 2011-11-03 | 2013-07-17 | 阳明大学 | 用于治疗和预防老化相关症状的方法和组分 |
| WO2013111081A1 (en) | 2012-01-24 | 2013-08-01 | Bar-Ilan University | Treatment of disease by modulation of sirt6 |
| CN103665166A (zh) * | 2012-09-03 | 2014-03-26 | 福又达生物科技股份有限公司 | 犬融合干扰素 |
| WO2014152993A1 (en) * | 2013-03-14 | 2014-09-25 | The Board Of Regents Of The University Of Oklahoma | Use of klotho nucleic acids or proteins for treatment of diabetes and diabetes-related conditions |
| JP2017513833A (ja) * | 2014-04-08 | 2017-06-01 | ユニヴァーシティー オブ サザン カリフォルニア | Ｖｉｉ型コラーゲンフィブロネクチンｉｉｉ型様リピートを有するポリペプチド組成物ならびに創傷の閉鎖および治癒のための治療方法 |
| KR20150135148A (ko) * | 2014-05-23 | 2015-12-02 | 주식회사 제넥신 | Pd-l1 융합 단백질 및 이의 용도 |
| CN107108710B (zh) * | 2014-10-24 | 2022-02-15 | 百时美施贵宝公司 | 修饰的fgf-21多肽及其用途 |
| KR20160088656A (ko) * | 2015-01-16 | 2016-07-26 | 주식회사유한양행 | 지속형 fgf21 융합 단백질 및 이를 포함하는 약학적 조성물 |
| US10882894B2 (en) * | 2015-08-11 | 2021-01-05 | Anie Philip | Peptidic TGF-beta antagonists |
-
2017
- 2017-05-22 AU AU2017268469A patent/AU2017268469C1/en active Active
- 2017-05-22 BR BR112018073861-1A patent/BR112018073861A2/pt unknown
- 2017-05-22 CN CN201780058862.1A patent/CN109844124B/zh active Active
- 2017-05-22 JP JP2018560974A patent/JP7632835B2/ja active Active
- 2017-05-22 EP EP17800329.9A patent/EP3458585A4/en active Pending
- 2017-05-22 CN CN202311189446.9A patent/CN117535350A/zh active Pending
- 2017-05-22 MX MX2018014256A patent/MX2018014256A/es unknown
- 2017-05-22 US US16/302,865 patent/US12281154B2/en active Active
- 2017-05-22 CA CA3025020A patent/CA3025020A1/en active Pending
- 2017-05-22 WO PCT/US2017/033815 patent/WO2017201527A2/en not_active Ceased
-
2018
- 2018-11-20 MX MX2022000085A patent/MX2022000085A/es unknown
-
2021
- 2021-11-30 JP JP2021194601A patent/JP7315284B2/ja active Active
-
2023
- 2023-03-20 JP JP2023044658A patent/JP2023078338A/ja active Pending
-
2024
- 2024-09-23 AU AU2024219991A patent/AU2024219991A1/en active Pending
- 2024-11-11 US US18/942,898 patent/US20250122267A1/en active Pending
-
2025
- 2025-02-25 JP JP2025028446A patent/JP2025078652A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019519221A5 (enExample) | ||
| US7351577B2 (en) | Adeno-associated vector compositions for expression of Factor VIII | |
| Skopenkova et al. | Muscle-specific promoters for gene therapy | |
| JP2022033855A (ja) | 加齢関連疾患及び症状の遺伝子治療法 | |
| JP2022033855A5 (enExample) | ||
| IL299325B2 (en) | Acid-alpha glucosidase variants and uses thereof | |
| JP7659550B2 (ja) | アデノ随伴ウイルスベクターに基づく遺伝性血管浮腫のための遺伝子治療 | |
| JP2002527493A (ja) | 標的細胞による第ｖｉｉｉ因子の発現のためのアデノ随伴ベクター | |
| CN113316639A (zh) | 用于治疗庞贝氏病的治疗性腺相关病毒 | |
| US6967018B2 (en) | Adiponectin gene therapy | |
| JP2012521750A (ja) | 肝硬変及び肝線維症の治療のための方法及び組成物 | |
| JP2022512689A (ja) | ジスルフィド結合により安定したポリペプチド組成物及びその使用方法 | |
| CN113692411A (zh) | 成纤维细胞生长因子23相关的低磷酸盐血症的基因治疗 | |
| JP2021532810A (ja) | 糖原病ｉｉｉの処置のためのミニｇｄｅ | |
| JP2022527597A (ja) | 筋肉発現のためのハイブリッドプロモーター | |
| JP2023076698A (ja) | ２１－ヒドロキシラーゼ欠損症のためのアデノ随伴ウイルス遺伝子療法 | |
| JP2025535114A (ja) | 中枢神経系における遺伝子発現のための核酸調節エレメント及び使用方法 | |
| JP2018526994A (ja) | ペット治療用ａａｖ−ｅｐｏ | |
| TWI883088B (zh) | 用於治療韓特氏病之腺相關病毒載體 | |
| JP2002534077A (ja) | トランスジェニック動物における分泌型ヒトアルファ−フェト蛋白質の発現 | |
| KR20230112672A (ko) | 신경변성 질환을 위한 유전자 요법 | |
| US20250327080A1 (en) | Rnas targeting activin a subunits | |
| CN120665952A (zh) | 一种修复肌萎缩侧索硬化致病突变基因的编辑系统 | |
| WO2025201333A1 (zh) | 递送Otof基因的双载体系统和其用途 | |
| WO2024097521A2 (en) | Compositions for treatment of osteogenesis imperfecta |