|
US1016745A
(en)
|
1911-04-11 |
1912-02-06 |
Edwin C Henrikson |
Table-caster.
|
|
US5139941A
(en)
|
1985-10-31 |
1992-08-18 |
University Of Florida Research Foundation, Inc. |
AAV transduction vectors
|
|
US5436146A
(en)
|
1989-09-07 |
1995-07-25 |
The Trustees Of Princeton University |
Helper-free stocks of recombinant adeno-associated virus vectors
|
|
US6268213B1
(en)
|
1992-06-03 |
2001-07-31 |
Richard Jude Samulski |
Adeno-associated virus vector and cis-acting regulatory and promoter elements capable of expressing at least one gene and method of using same for gene therapy
|
|
US5869305A
(en)
|
1992-12-04 |
1999-02-09 |
The University Of Pittsburgh |
Recombinant viral vector system
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5856152A
(en)
|
1994-10-28 |
1999-01-05 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV vector and methods of use therefor
|
|
US5652224A
(en)
|
1995-02-24 |
1997-07-29 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for gene therapy for the treatment of defects in lipoprotein metabolism
|
|
US5741683A
(en)
|
1995-06-07 |
1998-04-21 |
The Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
US6093570A
(en)
|
1995-06-07 |
2000-07-25 |
The University Of North Carolina At Chapel Hill |
Helper virus-free AAV production
|
|
US20020037867A1
(en)
|
1999-02-26 |
2002-03-28 |
James M. Wilson |
Method for recombinant adeno-associated virus-directed gene therapy
|
|
CA2264482A1
(en)
|
1996-09-06 |
1998-03-12 |
The Trustees Of The University Of Pennsylvania |
An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
|
|
US5866552A
(en)
|
1996-09-06 |
1999-02-02 |
The Trustees Of The University Of Pennsylvania |
Method for expressing a gene in the absence of an immune response
|
|
EP1696036B1
(en)
|
1996-09-06 |
2010-04-21 |
The Trustees of The University of Pennsylvania |
Use of recombinant adeno-associated virus in the manufacture of a medicament for gene therapy via muscle cells
|
|
WO1998010086A1
(en)
|
1996-09-06 |
1998-03-12 |
Trustees Of The University Of Pennsylvania |
Methods using cre-lox for production of recombinant adeno-associated viruses
|
|
AU4645697A
(en)
|
1996-09-11 |
1998-04-02 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Aav4 vector and uses thereof
|
|
CA2274146C
(en)
|
1996-12-05 |
2007-02-06 |
Introgene B.V. |
Genetic modification of primate hemopoietic repopulating stem cells
|
|
EP2327797B1
(en)
|
1997-04-01 |
2015-11-25 |
Illumina Cambridge Limited |
Method of nucleic acid sequencing
|
|
EP1007637B1
(en)
|
1997-04-14 |
2004-06-30 |
Cell Genesys, Inc. |
Methods for increasing the efficiency of recombinant aav product
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6251677B1
(en)
|
1997-08-25 |
2001-06-26 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
|
JP2001517454A
(ja)
|
1997-09-19 |
2001-10-09 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスの産生に有用な方法および細胞株
|
|
WO1999014354A1
(en)
|
1997-09-19 |
1999-03-25 |
The Trustees Of The University Of The Pennsylvania |
Methods and vector constructs useful for production of recombinant aav
|
|
AU9774998A
(en)
|
1997-09-19 |
1999-04-12 |
Trustees Of The University Of Pennsylvania, The |
Method for gene transfer using bcl2 and compositions useful therein
|
|
ATE286138T1
(de)
|
1998-03-20 |
2005-01-15 |
Univ Pennsylvania |
Zusammensetzungen und verfahren zur helfer-freien herstellung von rekombinante adeno-assoziierten viren
|
|
US6953690B1
(en)
|
1998-03-20 |
2005-10-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
US6146874A
(en)
|
1998-05-27 |
2000-11-14 |
University Of Florida |
Method of preparing recombinant adeno-associated virus compositions
|
|
DE69939169D1
(de)
|
1998-05-28 |
2008-09-04 |
Us Gov Health & Human Serv |
Aav5 vektoren und deren verwendung
|
|
US6759237B1
(en)
|
1998-11-05 |
2004-07-06 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
|
DE69936104T2
(de)
|
1998-11-05 |
2008-01-17 |
The Trustees Of The University Of Pennsylvania |
Nukleinsäuresequenzen des adeno-assoziierten virus des serotyps i, und vektoren und wirtszellen, die diese enthalten
|
|
EP1135468B1
(en)
|
1998-11-10 |
2010-01-06 |
University Of North Carolina At Chapel Hill |
Virus vectors and methods of making and administering the same
|
|
US6387368B1
(en)
|
1999-02-08 |
2002-05-14 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
|
JP4693244B2
(ja)
|
1999-03-18 |
2011-06-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法
|
|
US6258595B1
(en)
|
1999-03-18 |
2001-07-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
JP2003501067A
(ja)
|
1999-06-02 |
2003-01-14 |
トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
ヘルパーウイルスを要求する組み換えウイルス産生のために有用な組成物及び方法
|
|
US6596535B1
(en)
|
1999-08-09 |
2003-07-22 |
Targeted Genetics Corporation |
Metabolically activated recombinant viral vectors and methods for the preparation and use
|
|
US6365394B1
(en)
|
1999-09-29 |
2002-04-02 |
The Trustees Of The University Of Pennsylvania |
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
|
|
WO2001023001A2
(en)
|
1999-09-29 |
2001-04-05 |
The Trustees Of The University Of Pennsylvania |
Rapid peg-modification
|
|
AU7841400A
(en)
|
1999-10-01 |
2001-05-10 |
Genovo, Incorporated |
Production of recombinant aav using adenovirus comprising aav rep/cap genes
|
|
US7115391B1
(en)
|
1999-10-01 |
2006-10-03 |
Genovo, Inc. |
Production of recombinant AAV using adenovirus comprising AAV rep/cap genes
|
|
JP2003523180A
(ja)
|
1999-12-03 |
2003-08-05 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
多重のパッケージングシグナルを用いる組み換えアデノウイルスのパッケージングおよび収量を増加するための組成物および方法
|
|
US6821512B1
(en)
|
1999-12-03 |
2004-11-23 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for increasing packaging and yield of recombinant adenoviruses using multiple packaging signals
|
|
US6855314B1
(en)
|
2000-03-22 |
2005-02-15 |
The United States Of America As Represented By The Department Of Health And Human Services |
AAV5 vector for transducing brain cells and lung cells
|
|
US6468524B1
(en)
|
2000-03-22 |
2002-10-22 |
The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
AAV4 vector and uses thereof
|
|
JP2004514407A
(ja)
|
2000-04-28 |
2004-05-20 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
異種キャプシド中にシュードタイピングされたａａｖ５キャプシドおよびａａｖ５ベクターを含む組換えａａｖベクター
|
|
WO2001091802A1
(en)
*
|
2000-05-30 |
2001-12-06 |
Baylor College Of Medicine |
Chimeric viral vectors for gene therapy
|
|
AU6814901A
(en)
|
2000-06-01 |
2001-12-11 |
Univ North Carolina |
Methods and compounds for controlled release of recombinant parvovirus vectors
|
|
CN1293204C
(zh)
|
2000-08-30 |
2007-01-03 |
戴诺生物技术有限公司 |
等位基因的测定方法
|
|
IL158487A0
(en)
|
2001-05-18 |
2004-05-12 |
Wisconsin Alumni Res Found |
Method for the synthesis of dna sequences
|
|
AU2002324700A1
(en)
*
|
2001-08-14 |
2003-03-03 |
Bayer Ag |
Nucleic acid and amino acid sequences involved in pain
|
|
JP2005526001A
(ja)
|
2001-10-04 |
2005-09-02 |
アグイラルーコルドバ，カリオス，エスツアルド |
遺伝子療法用キメラ型ウイルスベクター
|
|
CN103589692B
(zh)
*
|
2001-11-13 |
2018-07-24 |
宾夕法尼亚大学托管会 |
检测和/或鉴定腺伴随病毒(aav)序列以及分离所鉴定的新型序列的方法
|
|
EP1463805B1
(en)
|
2001-12-17 |
2014-10-22 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses therefor
|
|
DK2359869T3
(en)
|
2001-12-17 |
2019-04-15 |
Univ Pennsylvania |
Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof
|
|
AU2002367943A1
(en)
|
2001-12-18 |
2003-12-22 |
University Of North Carolina At Chapel Hill |
Improved reagents and methods for producing parvoviruses
|
|
AU2003274397A1
(en)
|
2002-06-05 |
2003-12-22 |
University Of Florida |
Production of pseudotyped recombinant aav virions
|
|
EP1668143B1
(en)
|
2003-09-30 |
2013-03-20 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
|
|
DE23193606T1
(de)
|
2005-04-07 |
2024-02-15 |
The Trustees Of The University Of Pennsylvania |
Verfahren zur erhöhung der funktion eines aav-vektors
|
|
JP4495210B2
(ja)
|
2005-06-09 |
2010-06-30 |
パナソニック株式会社 |
振幅誤差補償装置及び直交度誤差補償装置
|
|
US7588772B2
(en)
|
2006-03-30 |
2009-09-15 |
Board Of Trustees Of The Leland Stamford Junior University |
AAV capsid library and AAV capsid proteins
|
|
DK2094086T3
(da)
|
2006-11-08 |
2013-11-25 |
Veritas Bio LLC |
Indgivelse in vivo af dobbeltstrenget rna til en målcelle
|
|
EP2058401A1
(en)
*
|
2007-10-05 |
2009-05-13 |
Genethon |
Widespread gene delivery to motor neurons using peripheral injection of AAV vectors
|
|
US9617548B2
(en)
*
|
2008-04-22 |
2017-04-11 |
Vib Vzw |
Liver-specific nucleic acid regulatory elements and methods and use thereof
|
|
MX2010012238A
(es)
|
2008-05-13 |
2011-04-11 |
Univ Washington |
Copolimeros dibloque y sus complejos con polinucleotidos destinados a introducirlos en celulas.
|
|
EP2364330B1
(en)
|
2008-11-06 |
2015-03-25 |
University Of Washington |
Multiblock copolymers
|
|
EP2352522A4
(en)
|
2008-11-06 |
2014-03-05 |
Univ Washington |
BISPECIFIC AUXILIARIES FOR INTRA-CELLULAR RELEASE
|
|
WO2010053572A2
(en)
|
2008-11-07 |
2010-05-14 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
|
EP2456786B2
(en)
|
2009-07-24 |
2017-04-19 |
Immune Design Corp |
Lentiviral vectors pseudotyped with a sindbis virus envelope glycoprotein
|
|
EP2281579A1
(en)
|
2009-08-05 |
2011-02-09 |
BioNTech AG |
Vaccine composition comprising 5'-Cap modified RNA
|
|
US9315825B2
(en)
|
2010-03-29 |
2016-04-19 |
The Trustees Of The University Of Pennsylvania |
Pharmacologically induced transgene ablation system
|
|
WO2011126808A2
(en)
|
2010-03-29 |
2011-10-13 |
The Trustees Of The University Of Pennsylvania |
Pharmacologically induced transgene ablation system
|
|
WO2012153638A1
(ja)
|
2011-05-12 |
2012-11-15 |
日立建機株式会社 |
建設機械
|
|
KR20220025112A
(ko)
|
2011-06-08 |
2022-03-03 |
샤이어 휴먼 지네틱 테라피즈 인크. |
Mrna 전달을 위한 지질 나노입자 조성물 및 방법
|
|
FR2977562B1
(fr)
|
2011-07-06 |
2016-12-23 |
Gaztransport Et Technigaz |
Cuve etanche et thermiquement isolante integree dans une structure porteuse
|
|
US9512073B2
(en)
|
2011-10-27 |
2016-12-06 |
Massachusetts Institute Of Technology |
Amino acid-, peptide-and polypeptide-lipids, isomers, compositions, and uses thereof
|
|
WO2013151664A1
(en)
*
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of proteins
|
|
WO2013143555A1
(en)
|
2012-03-26 |
2013-10-03 |
Biontech Ag |
Rna formulation for immunotherapy
|
|
CN104411338A
(zh)
*
|
2012-04-02 |
2015-03-11 |
现代治疗公司 |
用于产生与人类疾病相关的生物制剂和蛋白质的修饰多核苷酸
|
|
EA037448B1
(ru)
|
2012-06-08 |
2021-03-30 |
Этрис Гмбх |
Способ доставки в легкие терапевтической мрнк с pei и фармацевтическая композиция
|
|
AU2014296278C1
(en)
|
2013-07-30 |
2023-02-02 |
Genevant Sciences Gmbh |
Block copolymers and their conjugates or complexes with oligonucleotides
|
|
BR112016020688B1
(pt)
*
|
2014-03-09 |
2024-01-30 |
The Trustees Of The University Of Pennsylvania |
Vetores virais recombinantes, vírus adenoassociado recombinante, composição farmacêutica, bem como uso dos mesmos
|