JP2011530337A - 多数回服用量の注射装置 - Google Patents
多数回服用量の注射装置 Download PDFInfo
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- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
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- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
Abstract
【選択図】図1
Description
Claims (20)
- 医薬の連続的な服用分を医薬室から射出する形態とされた医薬の分与機構において、
ハウジングと
前記室から医薬の服用分を射出する形態とされたプランジャロッドと、
前記ハウジングと関係して、準備完了位置と、該準備完了位置に対する発射位置とを有するトリガーを備える作動機構と、を備え、前記トリガーは、
前記トリガーが前記プランジャロッドと関係して、前記プランジャロッドが所定の量の服用分の1つを射出する、全体として軸方向に並進移動する、前記準備完了位置から前記発射位置までの服用動作と、
該リセット動作する間、前記トリガーが前記プランジャロッドから非結合状態とされる、軸回転を含む、前記発射位置から前記準備完了位置までのリセット動作とにて連続的に動くようユーザにより操作される形態とされる、分与機構。 - 請求項1に記載の分与機構において、前記トリガーは、互いに連続的に配設された複数の準備完了位置と、発射位置とを備え、前記準備完了位置は、前記ハウジングの回りにて周方向に隔てられる、分与機構。
- 請求項1に記載の分与機構において、前記作動機構と関係して、服用動作及びリセット動作の少なくとも一部分を通じて前記作動機構の作動方向と反対の方向に後退する該作動機構の動作を防止する後退防止機構を更に備える、分与機構。
- 請求項3に記載の分与機構において、前記後退防止装置は、前記トリガーと関係し、該トリガーがリセット動作方向と反対の方向に向けて準備完了位置から後方に動くのを防止し、前記後退防止機構は、前記トリガーと関係して、該トリガーが服用動作方向と反対の方向に向けて発射位置から後方に動くのを防止するようにし、前記後退防止機構は、前記トリガーと関係して、該トリガーが前記リセット動作方向と反対の方向に向けて前記準備完了位置から後方へ動くのを防止するようにした、分与機構。
- 請求項4に記載の分与機構において、
前記トリガー及びハウジングの一方は、突起を含み、
前記トリガー及びハウジングの他方は、突起を受け入れ、且つ服用及びリセット動作を規定する軌道を含み、該軌道は、突起と係合すると共に、該突起が服用動作方向と反対に前記発射位置から後方へ動くのを防止する形態とした自由端を有してその内部に配設された第一のタブを備え、前記軌道は、前記突起と係合すると共に、前記突起がリセット動作方向と反対に前記準備完了位置から後方に動くのを防止する形態とした自由端を有してその内部に配設された第二のタブを備える、分与機構。 - 請求項1に記載の分与機構において、前記作動機構は、前記ハウジングと回転可能に関係して、且つ服用動作中、前記トリガーにより駆動方向に向けて回転駆動される駆動体を備える、分与機構。
- 請求項6に記載の分与機構において、前記駆動方向は、前記トリガーの発射位置と隣接する準備完了位置との間の前記回転間隔と反対の回転可能な方向であり、前記駆動体は、前記プランジャロッドと関係して、プランジャロッドが服用分の上記1つを射出するようにする、分与機構。
- 請求項6に記載の分与機構において、
前記ハウジング及びトリガーの一方は、第一の突起を含み、前記トリガー及び駆動体の他方は、第一の軌道を含み、該第一の軌道は、前記第一の突起を受け入れる形態とされ、且つ前記ハウジングに対する前記トリガーの服用及びリセット動作を規定する形態とされ、
前記トリガー及び駆動体の一方は、第二の突起を含み、前記トリガー及び駆動体の他方は、第二に軌道を含み、該第二の軌道は、前記第二の突起を受け入れる形態とされ、且つ前記トリガーの服用動作中、前記第二の突起に力を付与して前記駆動体を駆動方向に回転させる形態とされると共に、前記駆動体を回転させることなく、前記トリガーのリセット動作を許容する形態とされた、分与機構。 - 請求項8に記載の分与機構において、前記ハウジングは、第一の軌道を規定し、前記トリガーは、前記第一の突起を規定し、前記トリガーは、第二の軌道を規定し、前記駆動体は、第二の突起を規定し、前記第一の軌道は、複数の発射位置により連続的な列にて介在させた連続的な複数の準備完了位置を規定し、且つ、その間の相応する服用及びリセット動作のための経路を規定し、前記第二の軌道は、複数の駆動部分を備え、前記トリガーの連続的な服用動作中、前記第二の突起に交互に力を付与して前記駆動体を駆動方向に回転させ前記駆動体を駆動方向に回転させることにより、該トリガーが前記駆動体を連続的な列にて接続した服用動作の各々にて回転させるようにした、分与装置。
- 請求項8に記載の分与機構において、前記第二の軌道は、前記駆動体を回転させることなく、前記トリガーのリセット動作を許容するよう実質的に軸方向に整合したリセット部分を有する、分与機構。
- 請求項6に記載の分与機構において、前記駆動方向は、前記リセット動作中、前記トリガーの回転方向と反対である、分与機構。
- 注射器において、
請求項1の前記分与機構と、
ハウジングと関係し、且つ室を規定するキャリッジと
その内部にて医薬を密封するように前記室内に配設されたプランジャであって、プランジャロッドが該プランジャと関係してプランジャを末端方向に押して、服用分を射出するようにした前記プランジャと、
前記室と流体的に連通して服用分を患者に射出する針とを備える、注射器。 - 医薬の連続的な服用分を医薬室から射出する形態とされた医薬の分与機構において、
ハウジングと
前記室から医薬の服用分を射出する形態とされたプランジャロッドと、
前記ハウジングと関係して、準備完了位置と、該準備完了位置に対する発射位置とを有するトリガーを備える作動機構と、を備え、前記トリガーは、
服用動作中、前記トリガーが前記プランジャロッドと関係して、前記プランジャロッドが所定の量の服用分の1つを射出するようにする、前記発射位置から前記準備完了位置までの服用動作と、
リセット動作中、前記トリガーが前記プランジャロッドから非結合状態とされる、前記発射位置から前記準備完了位置までのリセット動作とにて連続的に動くようユーザにより操作される形態とされ、
前記作動機構と関係して作動機構の作動方向と反対の方向に向けて、服用及びリセット動作の少なくとも一部分を通じて、該作動機構の後方への動きを防止する後退防止機構を備える、医薬の分与機構。 - 請求項13に記載の分与機構において、
前記作動機構は、ハウジングと関係し、且つ服用動作中、トリガーにより回転駆動される駆動体を備え、
前記駆動体は、プランジャロッドと関係してプランジャロッドが服用分の前記1つを射出するようにし
前記後退防止機構は、駆動体が服用動作に抗して、トリガーに対して後方に動くのを防止する形態とされ、
前記トリガー及び駆動体の一方は突起を含み、
前記トリガー及び駆動体の他方は、服用動作中、突起の相対的な経路に面するステップ付き面を含み、該ステップ付き面は、後方に動く間、前記突起と係合し前記トリガーが後方へ動くのを防止する形態とされた、分与機構。 - 請求項14に記載の分与機構において、前記ステップ付き面は、実質的に平坦で且つ軸方向に面し、前記突起は、ステップ付き面の端縁を受け入れる切欠きを規定する、分与機構。
- 請求項14に記載の分与機構において、前記トリガー及び駆動体の前記他方は、前記ステップ付き面と対向し、且つ服用動作中、前記突起と係合して前記トリガーが駆動体をカム動作させてプランジャロッドを回転させ且つ駆動する傾斜面を備える、分与機構。
- 請求項14に記載の分与機構において、前記後退防止機構は、前記駆動体の前記ハウジングに対する後方への動きを防止する形態とされる、分与機構。
- 請求項14に記載の分与機構において、前記後退防止機構は、前記プランジャロッドの後方への動きを防止する形態とされる、分与機構。
- 請求項18に記載の分与機構において、前記後退防止機構は、所定の数の服用分が前記室から射出された後にのみ、プランジャロッドの後方への動きを防止する形態とされ、前記ハウジング内に配設された可撓性アームを含むことにより、前記作動機構を不作動にする形態とされ、前記プランジャロッドは、所定の数の服用分が前記室から射出された後、前記可撓性アームの一部分を軸方向外方に押す形態とされ、前記可撓性アームは、前記トリガーの一部分と係合し、リセット動作中、前記トリガーの更なる動きを防止して前記作動機構を不作動にする形態とされる、分与機構。
- 医薬の投薬装置において、
ハウジングと、
該ハウジングと関係し、且つ医薬を保持する医薬室を規定し、また、その一端内に可動に配設されたプランジャを含む、容器部分と、
内部キャビティと流体的に連通し、また、医薬を射出する形態とされた針と、減速機構とを備え、該減速機構は、
前記ハウジングとネジ係合関係にして、且つその回転時、プランジャを基端方向に動かす形態とされたプランジャロッドと、
全体として軸方向に可動のトリガーと、
前記トリガー及びプランジャロッドと関係し、前記トリガーが軸方向に動いたとき、回転し、これによりプランジャロッドをハウジングに対して回転させ、医薬を針を通じて射出する駆動体とを備え、該駆動体は、突起を含み、また、該トリガーは、該トリガーが軸方向と反対の方向に向けて動いたとき、前記突起と係合して、その後方への動きを防止するよう前記突起に面するステップ付き面を含む、医薬の投薬装置。
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US8636308P | 2008-08-05 | 2008-08-05 | |
US61/086,363 | 2008-08-05 | ||
PCT/US2009/052835 WO2010017285A2 (en) | 2008-08-05 | 2009-08-05 | Multiple dosage injector |
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JP5611208B2 JP5611208B2 (ja) | 2014-10-22 |
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US (5) | US8376993B2 (ja) |
EP (2) | EP2318075B1 (ja) |
JP (1) | JP5611208B2 (ja) |
AU (1) | AU2009279719B2 (ja) |
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US9144648B2 (en) | 2006-05-03 | 2015-09-29 | Antares Pharma, Inc. | Injector with adjustable dosing |
WO2007131013A1 (en) | 2006-05-03 | 2007-11-15 | Antares Pharma, Inc. | Two-stage reconstituting injector |
WO2009114542A1 (en) | 2008-03-10 | 2009-09-17 | Antares Pharma, Inc. | Injector safety device |
CA2724641C (en) | 2008-05-20 | 2020-03-24 | Avant Medical Corp. | Autoinjector system |
US8052645B2 (en) | 2008-07-23 | 2011-11-08 | Avant Medical Corp. | System and method for an injection using a syringe needle |
EP2318075B1 (en) * | 2008-08-05 | 2019-05-22 | Antares Pharma, Inc. | Multiple dosage injector |
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CA2732812A1 (en) | 2010-02-11 |
AU2009279719B2 (en) | 2015-07-23 |
AU2009279719A1 (en) | 2010-02-11 |
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US20190240419A1 (en) | 2019-08-08 |
JP5611208B2 (ja) | 2014-10-22 |
EP3581224A1 (en) | 2019-12-18 |
US8915889B2 (en) | 2014-12-23 |
US10300212B2 (en) | 2019-05-28 |
US11058824B2 (en) | 2021-07-13 |
EP2318075A4 (en) | 2017-05-24 |
CA2732812C (en) | 2017-10-31 |
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