JP2006523216A5 - - Google Patents
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- JP2006523216A5 JP2006523216A5 JP2006507475A JP2006507475A JP2006523216A5 JP 2006523216 A5 JP2006523216 A5 JP 2006523216A5 JP 2006507475 A JP2006507475 A JP 2006507475A JP 2006507475 A JP2006507475 A JP 2006507475A JP 2006523216 A5 JP2006523216 A5 JP 2006523216A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pharmaceutical composition
- treatment
- formula
- chronic myelogenous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 206010028980 Neoplasm Diseases 0.000 claims 10
- 201000011510 cancer Diseases 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 206010041067 Small cell lung cancer Diseases 0.000 claims 6
- 208000000587 small cell lung carcinoma Diseases 0.000 claims 6
- 208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 4
- 208000031261 Acute myeloid leukaemia Diseases 0.000 claims 3
- 208000021309 Germ cell tumor Diseases 0.000 claims 3
- 208000034176 Neoplasms, Germ Cell and Embryonal Diseases 0.000 claims 3
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 3
- 206010060862 Prostate cancer Diseases 0.000 claims 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 3
- 206010039491 Sarcoma Diseases 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 201000011243 gastrointestinal stromal tumor Diseases 0.000 claims 3
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 3
- 208000008585 mastocytosis Diseases 0.000 claims 3
- 201000001441 melanoma Diseases 0.000 claims 3
- 201000002528 pancreatic cancer Diseases 0.000 claims 3
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 3
- 208000010833 Chronic myeloid leukaemia Diseases 0.000 claims 2
- 208000033761 Myelogenous Chronic BCR-ABL Positive Leukemia Diseases 0.000 claims 2
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 claims 2
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- KTUFNOKKBVMGRW-UHFFFAOYSA-N imatinib Chemical compound C1CN(C)CCN1CC1=CC=C(C(=O)NC=2C=C(NC=3N=C(C=CN=3)C=3C=NC=CC=3)C(C)=CC=2)C=C1 KTUFNOKKBVMGRW-UHFFFAOYSA-N 0.000 claims 2
- 229960002411 imatinib Drugs 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000003981 vehicle Substances 0.000 claims 1
- ZBNZXTGUTAYRHI-UHFFFAOYSA-N Cc(cccc1Cl)c1NC(c1cnc(Nc2nc(C)nc(N3CCN(CCO)CC3)c2)[s]1)=O Chemical compound Cc(cccc1Cl)c1NC(c1cnc(Nc2nc(C)nc(N3CCN(CCO)CC3)c2)[s]1)=O ZBNZXTGUTAYRHI-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/395,503 US7125875B2 (en) | 1999-04-15 | 2003-03-24 | Cyclic protein tyrosine kinase inhibitors |
| PCT/US2004/008827 WO2004085388A2 (en) | 2003-03-24 | 2004-03-23 | Cyclic protein tyrosine kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006523216A JP2006523216A (ja) | 2006-10-12 |
| JP2006523216A5 true JP2006523216A5 (enExample) | 2007-04-26 |
Family
ID=33096777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507475A Pending JP2006523216A (ja) | 2003-03-24 | 2004-03-23 | 環状プロテインチロシンキナーゼインヒビター |
Country Status (34)
Families Citing this family (125)
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