JP2009511568A5 - - Google Patents
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- JP2009511568A5 JP2009511568A5 JP2008535136A JP2008535136A JP2009511568A5 JP 2009511568 A5 JP2009511568 A5 JP 2009511568A5 JP 2008535136 A JP2008535136 A JP 2008535136A JP 2008535136 A JP2008535136 A JP 2008535136A JP 2009511568 A5 JP2009511568 A5 JP 2009511568A5
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- 0 C*[C@]([C@]([C@]([C@@]([C@@]1O)O)O)O)[C@@]1O Chemical compound C*[C@]([C@]([C@]([C@@]([C@@]1O)O)O)O)[C@@]1O 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72563405P | 2005-10-13 | 2005-10-13 | |
| PCT/IB2006/004181 WO2007119108A2 (en) | 2005-10-13 | 2006-10-13 | Inositol derivatives and their uses in the treatment of diseases characterized by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012235331A Division JP2013018791A (ja) | 2005-10-13 | 2012-10-25 | イノシトール誘導体、ならびに異常なタンパク質の折りたたみまたは凝集、あるいはアミロイドの形成、沈着、蓄積または残存を特徴とする疾患の処置におけるその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009511568A JP2009511568A (ja) | 2009-03-19 |
| JP2009511568A5 true JP2009511568A5 (enExample) | 2009-11-26 |
Family
ID=37942269
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008535136A Withdrawn JP2009511568A (ja) | 2005-10-13 | 2006-10-13 | イノシトール誘導体、ならびに異常なタンパク質の折りたたみまたは凝集、あるいはアミロイドの形成、沈着、蓄積または残存を特徴とする疾患の処置におけるその使用 |
| JP2012235331A Pending JP2013018791A (ja) | 2005-10-13 | 2012-10-25 | イノシトール誘導体、ならびに異常なタンパク質の折りたたみまたは凝集、あるいはアミロイドの形成、沈着、蓄積または残存を特徴とする疾患の処置におけるその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012235331A Pending JP2013018791A (ja) | 2005-10-13 | 2012-10-25 | イノシトール誘導体、ならびに異常なタンパク質の折りたたみまたは凝集、あるいはアミロイドの形成、沈着、蓄積または残存を特徴とする疾患の処置におけるその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US20070111970A1 (enExample) |
| EP (1) | EP1940373B8 (enExample) |
| JP (2) | JP2009511568A (enExample) |
| CA (1) | CA2626005A1 (enExample) |
| WO (2) | WO2007119108A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7521481B2 (en) | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
| US9017724B2 (en) | 2004-02-24 | 2015-04-28 | The General Hospital Corporation | Catalytic radiofluorination |
| US8257680B1 (en) | 2004-02-24 | 2012-09-04 | The General Hospital Corporation | Catalytic radiofluorination |
| WO2007119108A2 (en) * | 2005-10-13 | 2007-10-25 | Waratah Pharmaceuticals Inc. | Inositol derivatives and their uses in the treatment of diseases characterized by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence |
| WO2008034244A1 (en) * | 2006-09-21 | 2008-03-27 | Waratah Pharmaceuticals Inc. | The combination of a cyclohexanehexol and a nsaid for the treatment of neurodegenerative diseases |
| WO2008061373A1 (en) * | 2006-11-24 | 2008-05-29 | Waratah Pharmaceuticals Inc. | Combination treatments for alzheimer's disease and similar diseases |
| US8450466B2 (en) | 2008-03-21 | 2013-05-28 | The General Hosptial Corporation | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders |
| AU2013248197B2 (en) * | 2008-03-21 | 2016-05-12 | The General Hospital Corporation | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders |
| KR101021078B1 (ko) * | 2008-07-22 | 2011-03-14 | 포항공과대학교 산학협력단 | 이노시톨 또는 트리할로스 유도체 및 이를 함유하는 퇴행성뇌신경계 질환 치료용 약학 조성물 |
| JP2011530539A (ja) * | 2008-08-08 | 2011-12-22 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インク． | 腫瘍形成を抑制する脂質化合物 |
| US20100279997A1 (en) * | 2009-05-04 | 2010-11-04 | Lindsay Burns Barbier | Analgesic that binds filamin a |
| GB0920985D0 (en) * | 2009-11-30 | 2010-01-13 | Queen Mary & Westfield College | Novel inositol phosphate derivatives |
| US8394858B2 (en) | 2009-12-03 | 2013-03-12 | Novartis Ag | Cyclohexane derivatives and uses thereof |
| JP2013519380A (ja) * | 2010-02-15 | 2013-05-30 | アッヴィ・インコーポレイテッド | ｓｃｙｌｌｏ−イノシトールを調製するための方法 |
| EP2390245A1 (en) * | 2010-05-26 | 2011-11-30 | Nabriva Therapeutics AG | Enantiomerically pure amines |
| US9320793B2 (en) * | 2010-07-14 | 2016-04-26 | Acumen Pharmaceuticals, Inc. | Method for treating a disease associated with soluble, oligomeric species of amyloid beta 1-42 |
| JP2013543513A (ja) | 2010-10-13 | 2013-12-05 | エラン ファーマシューティカルズ，インコーポレイテッド | シリトールおよび関連化合物の合成方法 |
| FR2989088B1 (fr) * | 2012-04-04 | 2014-08-29 | Univ Lorraine | Radiotraceur pour la maladie d'alzheimer |
| WO2014012054A1 (en) | 2012-07-13 | 2014-01-16 | Pain Therapeutics, Inc. | Alzheimer's disease assay in a living patent |
| GB201312499D0 (en) * | 2013-07-12 | 2013-08-28 | Isis Innovation | Therapeutic compounds |
| GB201416017D0 (en) | 2014-09-10 | 2014-10-22 | New Royal Holloway & Bedford | An Anticonvulsant Compound |
| KR102409017B1 (ko) | 2014-10-08 | 2022-06-16 | 텍사스 칠드런스 하스피탈 | 리포좀을 이용한 아밀로이드 플라크의 mri 영상화 |
| WO2018175537A1 (en) * | 2017-03-22 | 2018-09-27 | Dana-Farber Cancer Institute, Inc. | Selective inhibition of gluconeogenic activity |
| WO2021055670A1 (en) | 2019-09-20 | 2021-03-25 | Avx Corporation | Somatic cell-based electrical biosensor |
| KR102816558B1 (ko) | 2019-11-05 | 2025-06-05 | 아주대학교산학협력단 | 종양 괴사 인자 알파(TNF-α) 소분자 억제제 |
| JP7338918B1 (ja) | 2022-10-21 | 2023-09-05 | 築野食品工業株式会社 | イノシトール脂肪酸エステル |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4454151A (en) * | 1982-03-22 | 1984-06-12 | Syntex (U.S.A.) Inc. | Use of pyrrolo pyrroles in treatment of ophthalmic diseases |
| US4515722A (en) * | 1982-03-30 | 1985-05-07 | Merck & Co., Inc. | Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents |
| US4474806A (en) * | 1982-05-10 | 1984-10-02 | Merck & Co., Inc. | Sulfonyl or carbonyl inositol derivatives useful as anti-inflammatory/analgesic agents |
| US4952396A (en) * | 1986-11-19 | 1990-08-28 | Linus Pauling Institute Of Science & Medicine | Method of using phytic acid for inhibiting tumor growth |
| US4847082A (en) * | 1987-01-21 | 1989-07-11 | Robert Sabin | Method of treatment of Alzheimer's disease using phytic acid |
| US4758430A (en) * | 1987-01-21 | 1988-07-19 | Robert Sabin | Method of treatment of Alzheimer's disease using phytic acid |
| SE8904355D0 (sv) * | 1989-12-21 | 1989-12-21 | Perstorp Ab | Medicament |
| US5217959A (en) * | 1990-09-06 | 1993-06-08 | Robert Sabin | Method of treating multiple sclerosis with phytic acid |
| US5112814A (en) * | 1990-10-24 | 1992-05-12 | Robert Sabin | Method of treatment of Parkinson's disease using phytic acid |
| KR0185215B1 (ko) * | 1990-11-30 | 1999-05-01 | 요시다 쇼오지 | 서방성 안구삽입용 약제 |
| SE9102068L (sv) * | 1991-07-03 | 1993-01-04 | Perstorp Ab | Derivat av inositol, kompositioner innehaallande dessa samt anvaendning daerav |
| SE9200547L (sv) * | 1992-02-25 | 1993-06-14 | Perstorp Ab | En farmaceutisk komposition med foerbaettrad biotillgaenglighet avseende inositolfosfat |
| CA2146353C (en) * | 1992-10-05 | 2007-04-17 | Tomas Hudlicky | Syntheses of d-chiro-3-inosose and (+)-d-chiro-inositol |
| US5840294A (en) * | 1993-03-29 | 1998-11-24 | Queen's University At Kingston | Method for treating amyloidosis |
| US5972328A (en) * | 1993-03-29 | 1999-10-26 | Queen's University At Kingston | Method for treating amyloidosis |
| US5643562A (en) * | 1993-03-29 | 1997-07-01 | Queen's University Of Kingston | Method for treating amyloidosis |
| ES2202305T3 (es) * | 1993-04-05 | 2004-04-01 | Aveve N.V. | Hidrolisis de fitina y composicion de enzimas que tienen actividad hidrolizante de fitato. |
| CN1072637C (zh) * | 1993-08-11 | 2001-10-10 | 北兴化学工业株式会社 | D－手性肌醇的制造方法 |
| SE502574C2 (sv) * | 1994-01-25 | 1995-11-13 | Perstorp Ab | En farmaceutisk komposition med förbättrad biotillgänglighet hos inositolfosfat |
| US5550166A (en) * | 1995-03-17 | 1996-08-27 | Ostlund; Richard E. | Pinitol and derivatives thereof for the treatment of metabolic disorders |
| US5858326A (en) * | 1995-06-06 | 1999-01-12 | Neurochem, Inc. | Methods of increasing amyloid deposition |
| US5756541A (en) * | 1996-03-11 | 1998-05-26 | Qlt Phototherapeutics Inc | Vision through photodynamic therapy of the eye |
| US6232486B1 (en) * | 1996-06-11 | 2001-05-15 | Nutrimed Biotech | Molecular probes and modulators for PI-PLC and PI 3-kinase |
| US5880099A (en) * | 1996-09-20 | 1999-03-09 | The Regents Of The University Of California | Inositol polyphosphates and methods of using same |
| US5977078A (en) * | 1996-09-20 | 1999-11-02 | The Regents Of The Univesity Of California | Inositol polyphosphate derivatives and methods of using same |
| US5998485A (en) * | 1997-06-16 | 1999-12-07 | Cedars-Sinai Medical Center | Method for modulating immune response with inositol |
| US6153603A (en) * | 1997-06-27 | 2000-11-28 | Perstorp Ab | Method of treating angiogenesis in tumor tissue |
| US6310073B1 (en) * | 1998-07-28 | 2001-10-30 | Queen's University At Kingston | Methods and compositions to treat glycosaminoglycan-associated molecular interactions |
| US6818430B1 (en) * | 1999-06-07 | 2004-11-16 | Hokko Chemical Industry Co., Ltd. | Process for producing L-epi-2-inosose and novel process for producing epi-inositol |
| US6329256B1 (en) * | 1999-09-24 | 2001-12-11 | Advanced Micro Devices, Inc. | Self-aligned damascene gate formation with low gate resistance |
| CZ20021346A3 (cs) * | 1999-10-18 | 2003-06-18 | Muscletech Research And Development Inc. | Potravinový doplněk pro růst svalové hmoty a síly |
| US6331313B1 (en) * | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| DE10031955A1 (de) * | 2000-06-30 | 2002-01-17 | Deutsches Krebsforsch | Curcumin-Derivate mit gegenüber Curcumin verbesserter Wasserlöslichkeit und diese enthaltende Arzneimittel |
| US8034803B2 (en) * | 2001-02-06 | 2011-10-11 | Qlt Inc. | Photodynamic therapy of occult age-related macular degeneration |
| US7060695B2 (en) * | 2001-02-06 | 2006-06-13 | Qlt, Inc. | Method to prevent vision loss |
| US20030181531A1 (en) * | 2003-02-11 | 2003-09-25 | David Sherris | Compositions and methods of administering tubulin binding agents for the treatment of ocular diseases |
| US6599891B2 (en) * | 2001-07-20 | 2003-07-29 | Qlt Inc. | Treatment of macular edema |
| US20040058313A1 (en) * | 2002-04-24 | 2004-03-25 | Abreu Marcio Marc | Compositions, targets, methods and devices for the therapy of ocular and periocular disorders |
| US6723755B2 (en) * | 2002-06-12 | 2004-04-20 | Piotr Chomczynski | Method of treating rosacea |
| DE60230455D1 (de) * | 2002-10-17 | 2009-01-29 | Jingyu Liang | Natürliche verbindung für die behandlung von diabetes, deren herstellung und verwendung |
| US7521481B2 (en) * | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
| PT2058390E (pt) * | 2003-10-14 | 2013-04-24 | Hokko Chem Ind Co | Processo para a produção de cilo-inositol |
| US20060189582A1 (en) * | 2004-11-17 | 2006-08-24 | Mclaurin Joanne | Compositions and methods for treatment of disorders of protein aggregation |
| CA2488034C (en) * | 2004-11-19 | 2009-10-06 | Apotex Inc. | Process for the manufacture of 3-hydroxy-n-alkyl-1-cycloalkyl-6-alkyl-4-oxo-1,4-dihydropyridine-2-carboxamide and its related analogues |
| WO2007119108A2 (en) * | 2005-10-13 | 2007-10-25 | Waratah Pharmaceuticals Inc. | Inositol derivatives and their uses in the treatment of diseases characterized by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence |
| CA2652449A1 (en) * | 2006-05-19 | 2007-11-29 | Waratah Pharmaceuticals Inc. | Screening methods for amyloid beta modulators |
-
2006
- 2006-10-13 WO PCT/IB2006/004181 patent/WO2007119108A2/en not_active Ceased
- 2006-10-13 CA CA002626005A patent/CA2626005A1/en not_active Abandoned
- 2006-10-13 US US11/580,026 patent/US20070111970A1/en not_active Abandoned
- 2006-10-13 JP JP2008535136A patent/JP2009511568A/ja not_active Withdrawn
- 2006-10-13 WO PCT/CA2006/001679 patent/WO2007041855A1/en not_active Ceased
- 2006-10-13 EP EP06850456.2A patent/EP1940373B8/en not_active Not-in-force
- 2006-10-13 US US12/090,130 patent/US20090170957A1/en not_active Abandoned
-
2009
- 2009-11-11 US US12/616,496 patent/US20100105631A1/en not_active Abandoned
-
2012
- 2012-10-25 JP JP2012235331A patent/JP2013018791A/ja active Pending
-
2014
- 2014-02-05 US US14/173,175 patent/US20140155480A1/en not_active Abandoned