JP2011519873A5 - - Google Patents
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- Publication number
- JP2011519873A5 JP2011519873A5 JP2011507792A JP2011507792A JP2011519873A5 JP 2011519873 A5 JP2011519873 A5 JP 2011519873A5 JP 2011507792 A JP2011507792 A JP 2011507792A JP 2011507792 A JP2011507792 A JP 2011507792A JP 2011519873 A5 JP2011519873 A5 JP 2011519873A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- chloro
- trimethylpiperazine
- phenylindan
- trans
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200800647 | 2008-05-07 | ||
| DKPA200800647 | 2008-05-07 | ||
| DKPA200801392 | 2008-10-03 | ||
| DKPA200801392 | 2008-10-03 | ||
| DKPA200801519 | 2008-11-04 | ||
| DKPA200801519 | 2008-11-04 | ||
| PCT/DK2009/050107 WO2009135495A1 (en) | 2008-05-07 | 2009-05-07 | Method for treating cognitive deficits |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011519873A JP2011519873A (ja) | 2011-07-14 |
| JP2011519873A5 true JP2011519873A5 (enExample) | 2012-06-21 |
Family
ID=40870955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011507792A Pending JP2011519873A (ja) | 2008-05-07 | 2009-05-07 | 認知欠損を治療する方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20090306092A1 (enExample) |
| EP (1) | EP2285377A1 (enExample) |
| JP (1) | JP2011519873A (enExample) |
| KR (1) | KR20110021754A (enExample) |
| CN (1) | CN102065861B (enExample) |
| AU (1) | AU2009243813B2 (enExample) |
| BR (1) | BRPI0912223A2 (enExample) |
| CA (1) | CA2722374A1 (enExample) |
| CO (1) | CO6311083A2 (enExample) |
| EA (1) | EA018927B1 (enExample) |
| IL (1) | IL209084A0 (enExample) |
| MX (1) | MX2010012037A (enExample) |
| NZ (1) | NZ589571A (enExample) |
| WO (1) | WO2009135495A1 (enExample) |
| ZA (1) | ZA201007912B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0919165A2 (pt) * | 2008-10-03 | 2015-12-08 | Lundbeck & Co As H | composição farmacêutica,e, uso de um composto |
| TWI552751B (zh) * | 2011-06-20 | 2016-10-11 | Ｈ 朗德貝克公司 | 投予４－（（１ｒ，３ｓ）－６－氯－３－苯基－二氫茚－１－基）－１，２，２－三甲基－哌及其鹽用於治療精神分裂症的方法 |
| PL3135656T3 (pl) | 2011-06-20 | 2019-07-31 | H. Lundbeck A/S | Deuterowane 1-piperazyno-3-fenyloindany do leczenia schizofrenii |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| US20210395208A1 (en) * | 2018-10-29 | 2021-12-23 | H. Lundeck A/S | Amorphous compounds of formula (i) and amorphous compounds of formula (i) salts |
| EP3891134A1 (en) | 2018-12-03 | 2021-10-13 | H. Lundbeck A/S | Prodrugs of 4-((1r,3s)-6-chloro-3-phenyl-2,3-dihydro-1h-inden-1-yl)-1,2,2-trimethylpiperazine and 4-((1/r,3s)-6-chloro-3-(phenyl-d5)-2,3-dihydro-1h-inden-1-yl)-2,2-dimethy-1-(methyl-d3)piperazine |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4031216A (en) * | 1974-08-12 | 1977-06-21 | Knoll A.G. Chemische Fabriken | 3-(3,4-Dialkoxy-benzyl)-3-methyl-piperazines |
| IE50867B1 (en) * | 1980-02-29 | 1986-08-06 | Kefalas As | Indane derivatives |
| DE3139970A1 (de) * | 1981-10-08 | 1983-04-28 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue carbonsaeurederivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
| US5026853A (en) * | 1987-04-01 | 1991-06-25 | Janssen Pharmaceutica N.V. | 4-substituted-2(or 3)aminocarbonyl-1-piperazineacetamide |
| US5466806A (en) * | 1989-02-08 | 1995-11-14 | Biochem Pharma Inc. | Processes for preparing substituted 1,3-oxathiolanes with antiviral properties |
| CA2091204C (en) * | 1992-03-11 | 1997-04-08 | Ronald J. Mattson | Antiischemic-piperazinyl and piperidinyl-cyclohexanes |
| DK55192D0 (da) * | 1992-04-28 | 1992-04-28 | Lundbeck & Co As H | 1-piperazino-1,2-dihydroindenderivater |
| CA2132411A1 (en) * | 1994-09-19 | 1996-03-20 | Michael Trani | Enzymatic esterification of long-chain racemic acids and alcohols |
| US6410794B1 (en) * | 1994-12-16 | 2002-06-25 | Uop Llc | Process for preparation of pharmaceutically desired chiral tetralone from tetralones |
| US6455736B1 (en) * | 1994-12-16 | 2002-09-24 | Uop Llc | Process for preparation of pharmaceutically desired sertraline and sertraline analogs |
| US5807897A (en) * | 1996-03-01 | 1998-09-15 | Zeneca Limited | Aminotetralin derivative and compositions and method of use thereof |
| ATE255555T1 (de) * | 1998-05-01 | 2003-12-15 | Pfizer Prod Inc | Verfahren zur herstellung von enantiomeren reinem oder optisch angereicherter sertraline-tetralon durch kontinuierliche chromatographie |
| DE19824470A1 (de) * | 1998-05-30 | 1999-12-02 | Boehringer Ingelheim Pharma | Neue Neurokininantagonisten, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
| FR2786769B1 (fr) * | 1998-12-04 | 2002-10-25 | Synthelabo | Derives de 2,5-diazabicyclo[2.2.1]heptane, leur preparation et leur application en therapeutique |
| IN187170B (enExample) * | 2000-01-04 | 2002-02-23 | Sun Pharmaceutical Ind Ltd | |
| US7396542B2 (en) * | 2001-12-28 | 2008-07-08 | Teva Pharmaceutical Industries Ltd. | Stable pharmaceutical formulation of paroxetine hydrochloride anhydrous and a process for preparation thereof |
| AU2003284899A1 (en) * | 2002-10-29 | 2004-05-25 | Miicro, Inc. | Novel combination therapy for schizophrenia focused on improved cognition: 5-ht-2a/d2 blockade with adjunctive blockade of prefrontal da reuptake |
| PL1658277T3 (pl) * | 2003-08-18 | 2012-10-31 | H Lundbeck As | Sól bursztynianowa i malonianowa trans-4-((1R,3S)-6-chloro-3-fenyloindan-1-ylo)-1,2,2-tri-metylopiperazyny i zastosowanie jako lek |
| TWI376373B (en) * | 2005-02-16 | 2012-11-11 | Lundbeck & Co As H | Crystalline base of a pharmaceutical compound |
| TW200640891A (en) * | 2005-02-16 | 2006-12-01 | Lundbeck & Co As H | Tartrate and malate salts of a pharmarceutical compound |
| JP2008530039A (ja) * | 2005-02-16 | 2008-08-07 | ハー・ルンドベック・アクチエゼルスカベット | トランス−１−（（１ｒ，３ｓ）−６−クロロ−３−フェニルインダン−１−イル）−３，３−ジメチルピペラジンの酒石酸塩およびリンゴ酸塩 |
| TW200817400A (en) * | 2006-05-30 | 2008-04-16 | Elbion Ag | Pyrido [3,2-e] pyrazines, their use as inhibitors of phosphodiesterase 10, and processes for preparing them |
| BRPI0919165A2 (pt) * | 2008-10-03 | 2015-12-08 | Lundbeck & Co As H | composição farmacêutica,e, uso de um composto |
-
2009
- 2009-05-07 WO PCT/DK2009/050107 patent/WO2009135495A1/en not_active Ceased
- 2009-05-07 MX MX2010012037A patent/MX2010012037A/es not_active Application Discontinuation
- 2009-05-07 JP JP2011507792A patent/JP2011519873A/ja active Pending
- 2009-05-07 AU AU2009243813A patent/AU2009243813B2/en not_active Ceased
- 2009-05-07 EA EA201071273A patent/EA018927B1/ru not_active IP Right Cessation
- 2009-05-07 EP EP09741768A patent/EP2285377A1/en not_active Withdrawn
- 2009-05-07 US US12/437,363 patent/US20090306092A1/en not_active Abandoned
- 2009-05-07 BR BRPI0912223A patent/BRPI0912223A2/pt not_active IP Right Cessation
- 2009-05-07 CN CN2009801162104A patent/CN102065861B/zh not_active Expired - Fee Related
- 2009-05-07 KR KR1020107024956A patent/KR20110021754A/ko not_active Withdrawn
- 2009-05-07 NZ NZ589571A patent/NZ589571A/en not_active IP Right Cessation
- 2009-05-07 CA CA2722374A patent/CA2722374A1/en not_active Abandoned
-
2010
- 2010-11-02 IL IL209084A patent/IL209084A0/en unknown
- 2010-11-04 ZA ZA2010/07912A patent/ZA201007912B/en unknown
- 2010-11-30 CO CO10150622A patent/CO6311083A2/es not_active Application Discontinuation
-
2011
- 2011-05-05 US US13/101,176 patent/US20110207744A1/en not_active Abandoned
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