|
GB1039113A
(en)
|
1964-08-06 |
1966-08-17 |
Ucb Sa |
New n-substituted lactams
|
|
GB1309692A
(en)
|
1970-02-13 |
1973-03-14 |
Ucb Sa |
N-substituted lactams
|
|
IT1045043B
(it)
*
|
1975-08-13 |
1980-04-21 |
Isf Spa |
Derivati pirrolidinici
|
|
IT1075280B
(it)
*
|
1977-02-11 |
1985-04-22 |
Isf Spa |
Procedimento per la preparazione di derivati pirrolidinici
|
|
BE864269A
(fr)
*
|
1977-03-03 |
1978-06-16 |
Parke Davis & Co |
Nouveaux n-(aminoalkyl substitue)-2-oxo-1-pyrrolidine-acetamides et procedes pour les produire
|
|
DE2960194D1
(en)
*
|
1978-05-08 |
1981-04-16 |
Ucb Sa |
Lactam-n-acetic acids, their amides, process for their preparation and therapeutic compositions containing them
|
|
US4654370A
(en)
*
|
1979-03-12 |
1987-03-31 |
Abbott Laboratories |
Glyceryl valproates
|
|
US4372960A
(en)
*
|
1980-12-12 |
1983-02-08 |
Warner-Lambert Company |
Quaternary derivatives of N-(substituted-aminoalkyl)-2-oxo-1-pyrrolidine-acetamides as cognition activators
|
|
FR2515179A1
(fr)
*
|
1981-07-24 |
1983-04-29 |
Hoffmann La Roche |
Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
|
|
IL67623A
(en)
*
|
1983-01-05 |
1984-09-30 |
Teva Pharma |
1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it
|
|
IL72381A
(en)
|
1983-07-20 |
1988-03-31 |
Sanofi Sa |
Pharmaceutical composition based on valproic acid
|
|
US4558070A
(en)
|
1983-10-26 |
1985-12-10 |
Abbott Laboratories |
Acid salts of valproic acid
|
|
GB8412357D0
(en)
*
|
1984-05-15 |
1984-06-20 |
Ucb Sa |
Pharmaceutical composition
|
|
GB8412358D0
(en)
*
|
1984-05-15 |
1984-06-20 |
Ucb Sa |
Pharmaceutical composition
|
|
US4668687A
(en)
*
|
1984-07-23 |
1987-05-26 |
Bristol-Myers Company |
Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones
|
|
US4913906B1
(en)
*
|
1985-02-28 |
2000-06-06 |
Yissum Res Dev Co |
Controlled release dosage form of valproic acid
|
|
JPS6222785A
(ja)
*
|
1985-07-23 |
1987-01-30 |
Sanwa Kagaku Kenkyusho:Kk |
新規な２−オキソピロリジン化合物及びその塩、その製法並びにこれらを有効成分とする脳機能障害の予防及び治療剤
|
|
IT1190133B
(it)
|
1986-06-19 |
1988-02-10 |
Chiesi Farma Spa |
Derivati di acido valproico e di acido (e)-2-valproenoico,procedimento per la loro preparazione e relative composizioni farmaceutiche
|
|
DE3709230A1
(de)
|
1987-03-20 |
1988-10-06 |
Desitin Arzneimittel Gmbh |
Neues calciumsalz der valproinsaeure
|
|
JPS6422883A
(en)
*
|
1987-07-17 |
1989-01-25 |
Sanwa Kagaku Kenkyusho Co |
1-pyrrolidine acetamide derivative, its salt, production thereof and prophylactic and remedial agent for cereral dysfunction containing said derivative and salt as active ingredient
|
|
ES2026198T3
(es)
*
|
1987-07-22 |
1992-04-16 |
Farvalsa Ag |
Compuesto a base de acido valproico solido, estable a la humedad y metodo para su preparacion.
|
|
AU625157B2
(en)
|
1989-01-17 |
1992-07-02 |
F. Hoffmann-La Roche Ag |
Cyclohexaneacetamide derivatives
|
|
FR2643556B1
(fr)
*
|
1989-02-27 |
1993-03-05 |
Sanofi Sa |
Composition pharmaceutique a liberation prolongee d'acide valproique
|
|
IT1231477B
(it)
*
|
1989-07-12 |
1991-12-07 |
Sigma Tau Ind Farmaceuti |
(pirrolidin-2-one-1-il) acetammidi quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti
|
|
CA2067614C
(en)
*
|
1991-05-02 |
2002-07-30 |
Eiichi Otomo |
Agent for improving dementia
|
|
US5439930A
(en)
*
|
1992-04-14 |
1995-08-08 |
Russian-American Institute For New Drug Development |
Biologically active n-acylprolydipeptides having antiamnestic, antihypoxic and anorexigenic effects
|
|
US5440023A
(en)
|
1992-09-18 |
1995-08-08 |
Beckman Instruments, Inc. |
Method for making valproic acid derivatives
|
|
GB9319732D0
(en)
*
|
1993-09-24 |
1993-11-10 |
Ucb Sa |
Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety
|
|
US5468733A
(en)
|
1993-09-30 |
1995-11-21 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
US5516759A
(en)
|
1994-12-08 |
1996-05-14 |
Tap Holdings Inc. |
LHRH antagonists having lactam groups at the N-terminus
|
|
IT1285801B1
(it)
*
|
1996-10-10 |
1998-06-24 |
Sigma Tau Ind Farmaceuti |
Procedimento migliorato per la preparazione dell'acido valproico
|
|
US6131106A
(en)
|
1998-01-30 |
2000-10-10 |
Sun Microsystems Inc |
System and method for floating-point computation for numbers in delimited floating point representation
|
|
US6620802B1
(en)
*
|
1999-11-23 |
2003-09-16 |
Corcept Therapeutics, Inc. |
Methods of treating mild cognitive impairment using a glucocorticoid-specific receptor antagonist
|
|
EE200200274A
(et)
|
1999-12-01 |
2003-06-16 |
Ucb, S.A. |
Pürrolidiinatseetamiidi derivaadi kasutamine ravimi valmistamiseks, mis on ette nähtud kesknärvisüsteemi häirete ravimiseks, ja farmatseutiline kompositsioon
|
|
GB0004297D0
(en)
|
2000-02-23 |
2000-04-12 |
Ucb Sa |
2-oxo-1 pyrrolidine derivatives process for preparing them and their uses
|
|
US7608636B2
(en)
*
|
2000-12-28 |
2009-10-27 |
Hamilton Pharmaceuticals, Inc. |
Medicines for treatment and prevention of neurogenic pain
|
|
US6610326B2
(en)
*
|
2001-02-16 |
2003-08-26 |
Andrx Corporation |
Divalproex sodium tablets
|
|
EP1379236A4
(en)
*
|
2001-02-23 |
2009-01-21 |
Ucb Sa |
TREATMENT OF TICS, TREMOR AND RELATED DISORDER
|
|
EP1395560A1
(en)
|
2001-05-23 |
2004-03-10 |
Ucb, S.A. |
2-oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivativ es for the treatment of epilepsy and other neurological disorders
|
|
CA2457982C
(en)
*
|
2001-08-22 |
2009-11-03 |
Daiichi Pharmaceutical Co., Ltd. |
Use of nefiracetam for treating neurodegeneration
|
|
MXPA04003516A
(es)
|
2001-10-16 |
2004-07-23 |
Memory Pharm Corp |
Derivados de 4-(4-alcoxi-3-hidroxifenil)-2-pirrolidona como inhibidores de pde-4 para el tratamiento de sindromes neurologicos.
|
|
US20040116506A1
(en)
*
|
2002-06-20 |
2004-06-17 |
Krusz John Claude |
Use of levetiracetam for treating or preventing acute headaches
|
|
US7557137B2
(en)
*
|
2002-08-05 |
2009-07-07 |
Bristol-Myers Squibb Company |
Gamma-lactams as beta-secretase inhibitors
|
|
AU2003298766A1
(en)
*
|
2002-12-03 |
2004-06-23 |
Ucb, S.A. |
Methods for the identification of agents for the treatment of seizures, neurological diseases, endocrinopathies and hormonal diseases
|
|
US7090985B2
(en)
*
|
2002-12-03 |
2006-08-15 |
Ucb, S.A. |
Methods for the identification of agents for the treatment of seizures, neurological diseases, endocrinopathies and hormonal diseases
|
|
ITMI20030573A1
(it)
*
|
2003-03-24 |
2004-09-25 |
Nikem Research Srl |
Composti ad azione nootropica, loro preparazione,
|
|
TW200508197A
(en)
|
2003-03-31 |
2005-03-01 |
Ucb Sa |
Indolone-acetamide derivatives, processes for preparing them and their uses
|
|
WO2005054188A1
(en)
|
2003-12-02 |
2005-06-16 |
Ucb, S.A. |
Imidazole derivatives, processes for preparing them and their uses
|
|
WO2005108358A2
(en)
|
2004-04-22 |
2005-11-17 |
Eli Lilly And Company |
Pyrrolidine derivatives useful as bace inhibitors
|
|
ZA200610274B
(en)
|
2004-06-11 |
2008-06-25 |
Ucb Sa |
Process for preparing 2-oxo-1-pyrrolidine derivatives by intramolecular allylation
|
|
US20060063707A1
(en)
*
|
2004-09-17 |
2006-03-23 |
Lifelike Biomatic, Inc. |
Compositions for enhancing memory and methods therefor
|
|
NZ556630A
(en)
*
|
2005-01-27 |
2010-12-24 |
Alembic Ltd |
Extended release formulation of levetiracetam including a hydrophilic rate controlling polymer
|
|
US20070298098A1
(en)
*
|
2005-02-16 |
2007-12-27 |
Elan Pharma International Limited |
Controlled Release Compositions Comprising Levetiracetam
|
|
EP1871363A4
(en)
*
|
2005-03-30 |
2009-01-21 |
Genpharm Inc |
COMBINED STAGE PROCESS FOR PHARMACEUTICAL COMPOSITIONS
|
|
EP1912966A2
(en)
|
2005-06-01 |
2008-04-23 |
Ucb, S.A. |
2-oxo-1-pyrrolidine derivatives and their therapeutic use on the central nervous system
|
|
EP1731149A1
(en)
*
|
2005-06-08 |
2006-12-13 |
Ucb S.A. |
Use of 2-oxo-1-pyrrolidone derivatives for the treatment of diseases characterized by progressive myoclonic epilepsy
|
|
GB0517740D0
(en)
|
2005-08-31 |
2005-10-12 |
Novartis Ag |
Organic compounds
|
|
WO2007065595A2
(en)
|
2005-12-07 |
2007-06-14 |
Ucb Pharma, S.A. |
Xanthine derivatives, processes for preparing them and their uses
|
|
US20100216734A1
(en)
*
|
2006-03-08 |
2010-08-26 |
Braincells, Inc. |
Modulation of neurogenesis by nootropic agents
|
|
EP1991212A1
(en)
|
2006-03-08 |
2008-11-19 |
Braincells, Inc. |
Modulation of neurogenesis by nootropic agents
|
|
US7858611B2
(en)
*
|
2006-05-09 |
2010-12-28 |
Braincells Inc. |
Neurogenesis by modulating angiotensin
|
|
MX2008014320A
(es)
*
|
2006-05-09 |
2009-03-25 |
Braincells Inc |
Neurogenesis mediada por el receptor de 5-hidroxitriptamina.
|
|
US20080014264A1
(en)
*
|
2006-07-13 |
2008-01-17 |
Ucb, S.A. |
Novel pharmaceutical compositions comprising levetiracetam
|
|
EP2051696A2
(en)
*
|
2006-08-18 |
2009-04-29 |
Morton Grove Pharmaceuticals, Inc. |
Stable liquid levetiracetam compositions and methods
|
|
WO2008095221A1
(en)
|
2007-02-07 |
2008-08-14 |
Gosforth Centre (Holdings) Pty Ltd |
Treatment of adhd
|
|
WO2008132139A2
(en)
|
2007-04-27 |
2008-11-06 |
Ucb Pharma S.A. |
New heterocyclic derivatives useful for the treatment of cns disorders
|
|
WO2009038412A2
(en)
|
2007-09-21 |
2009-03-26 |
Lg Life Sciences, Ltd. |
Beta-secretase inhibiting compounds
|
|
US20090176740A1
(en)
|
2007-11-30 |
2009-07-09 |
Phillips Ii Dauglas James |
Treatment of neurological conditions by the co-administration of aniracetam and l-alpha glycerylphosphorylcholine
|
|
BRPI0908421C1
(pt)
*
|
2008-03-03 |
2021-05-25 |
Ucb Biopharma Sprl |
solução estável de um composto farmacêutico
|
|
JP2010024156A
(ja)
|
2008-07-16 |
2010-02-04 |
Ucb Pharma Sa |
レベチラセタムを含む医薬組成物
|
|
CN102170874A
(zh)
|
2008-08-06 |
2011-08-31 |
高思福斯中心（控股）有限公司 |
治疗精神病学障碍的组合物和方法
|
|
DK3260118T3
(da)
|
2008-10-16 |
2021-04-19 |
Univ Johns Hopkins |
Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion
|
|
US9125898B2
(en)
*
|
2008-11-14 |
2015-09-08 |
Neurotune Ag |
Acetam derivatives for pain relief
|
|
DK2358360T3
(en)
|
2008-11-18 |
2016-12-12 |
Ucb Biopharma Sprl |
EXTENDED release formulations comprising one 2-OXO-1 PYRROLIDIN DERIVATIVE
|
|
CA2747396C
(en)
|
2009-01-29 |
2015-12-08 |
Serge Cuypers |
Pharmaceutical compositions comprising 2-oxo-1-pyrrolidine derivatives
|
|
WO2010089372A1
(en)
|
2009-02-09 |
2010-08-12 |
Ucb Pharma, S.A. |
Pharmaceutical compositions comprising brivaracetam
|
|
WO2011015349A2
(en)
|
2009-08-07 |
2011-02-10 |
Ucb Pharma, S.A. |
Methods for enhancing the cognitive function
|
|
US10925834B2
(en)
*
|
2015-05-22 |
2021-02-23 |
Agenebio, Inc. |
Extended release pharmaceutical compositions of levetiracetam
|