JPS6422883A - 1-pyrrolidine acetamide derivative, its salt, production thereof and prophylactic and remedial agent for cereral dysfunction containing said derivative and salt as active ingredient - Google Patents

1-pyrrolidine acetamide derivative, its salt, production thereof and prophylactic and remedial agent for cereral dysfunction containing said derivative and salt as active ingredient

Info

Publication number
JPS6422883A
JPS6422883A JP62177173A JP17717387A JPS6422883A JP S6422883 A JPS6422883 A JP S6422883A JP 62177173 A JP62177173 A JP 62177173A JP 17717387 A JP17717387 A JP 17717387A JP S6422883 A JPS6422883 A JP S6422883A
Authority
JP
Japan
Prior art keywords
salt
derivative
prophylactic
formula
represent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62177173A
Other languages
English (en)
Inventor
Masatsune Kurono
Tsunemasa Suzuki
Tomoo Suzuki
Kiyotaka Hirooka
Koji Matsumoto
Hiroshi Ozawa
Kiichi Sawai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanwa Kagaku Kenkyusho Co Ltd
Original Assignee
Sanwa Kagaku Kenkyusho Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanwa Kagaku Kenkyusho Co Ltd filed Critical Sanwa Kagaku Kenkyusho Co Ltd
Priority to JP62177173A priority Critical patent/JPS6422883A/ja
Priority to US07/217,523 priority patent/US4939126A/en
Priority to DE3854981T priority patent/DE3854981T2/de
Priority to EP88111361A priority patent/EP0299495B1/en
Publication of JPS6422883A publication Critical patent/JPS6422883A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP62177173A 1987-07-17 1987-07-17 1-pyrrolidine acetamide derivative, its salt, production thereof and prophylactic and remedial agent for cereral dysfunction containing said derivative and salt as active ingredient Pending JPS6422883A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP62177173A JPS6422883A (en) 1987-07-17 1987-07-17 1-pyrrolidine acetamide derivative, its salt, production thereof and prophylactic and remedial agent for cereral dysfunction containing said derivative and salt as active ingredient
US07/217,523 US4939126A (en) 1987-07-17 1988-07-11 1-pyrrolidineacetamide derivatives and use thereof
DE3854981T DE3854981T2 (de) 1987-07-17 1988-07-14 1-Pyrrolidinacetamid-Derivate und ihre Verwendung
EP88111361A EP0299495B1 (en) 1987-07-17 1988-07-14 1-Pyrrolidineacetamide derivatives and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62177173A JPS6422883A (en) 1987-07-17 1987-07-17 1-pyrrolidine acetamide derivative, its salt, production thereof and prophylactic and remedial agent for cereral dysfunction containing said derivative and salt as active ingredient

Publications (1)

Publication Number Publication Date
JPS6422883A true JPS6422883A (en) 1989-01-25

Family

ID=16026458

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62177173A Pending JPS6422883A (en) 1987-07-17 1987-07-17 1-pyrrolidine acetamide derivative, its salt, production thereof and prophylactic and remedial agent for cereral dysfunction containing said derivative and salt as active ingredient

Country Status (4)

Country Link
US (1) US4939126A (ja)
EP (1) EP0299495B1 (ja)
JP (1) JPS6422883A (ja)
DE (1) DE3854981T2 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208345A (en) * 1990-12-17 1993-05-04 Merrell Dow Pharmaceuticals Inc. Process for the production of (S)-vinyl and allenyl gaba
US5679798A (en) * 1996-11-22 1997-10-21 Mona Industries, Inc. Silicone monomers having a carboxyl functional group thereon
WO1998022478A1 (en) * 1996-11-22 1998-05-28 Mona Industries, Inc. Silicone monomers and oligomers having a carboxyl functional group thereon
GB2382575A (en) * 2001-10-30 2003-06-04 Amedis Pharm Ltd 1-aza-4-silacyclohexanes as pharmaceuticals
CN107243007A (zh) 2008-10-16 2017-10-13 约翰斯.霍普金斯大学 改善认知功能的方法和组合物
BR112012019923A2 (pt) * 2010-02-09 2016-08-09 Univ Johns Hopkins métodos e composições para melhorar a função cognitiva
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
EP2968220B1 (en) 2013-03-15 2021-05-05 Agenebio, Inc. Methods and compositions for improving cognitive function
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
CN107810002B (zh) 2015-05-22 2021-01-05 艾吉因生物股份有限公司 左乙拉西坦的延时释放药物组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
JPS59122430A (ja) * 1982-12-29 1984-07-14 Chisso Corp シリルアルキル化された５−フルオロウラシル類
JPS6222785A (ja) * 1985-07-23 1987-01-30 Sanwa Kagaku Kenkyusho:Kk 新規な２−オキソピロリジン化合物及びその塩、その製法並びにこれらを有効成分とする脳機能障害の予防及び治療剤

Also Published As

Publication number Publication date
EP0299495B1 (en) 1996-02-07
US4939126A (en) 1990-07-03
DE3854981D1 (de) 1996-03-21
EP0299495A3 (en) 1991-03-13
EP0299495A2 (en) 1989-01-18
DE3854981T2 (de) 1996-09-05

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