JP2016175884A5 - - Google Patents
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- Publication number
- JP2016175884A5 JP2016175884A5 JP2015059041A JP2015059041A JP2016175884A5 JP 2016175884 A5 JP2016175884 A5 JP 2016175884A5 JP 2015059041 A JP2015059041 A JP 2015059041A JP 2015059041 A JP2015059041 A JP 2015059041A JP 2016175884 A5 JP2016175884 A5 JP 2016175884A5
- Authority
- JP
- Japan
- Prior art keywords
- fibroma
- neural
- neurofibroma
- external
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010016629 fibroma Diseases 0.000 claims 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 4
- 230000001537 neural effect Effects 0.000 claims 4
- 201000004404 Neurofibroma Diseases 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000002674 ointment Substances 0.000 claims 2
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 claims 2
- 239000003860 topical agent Substances 0.000 claims 2
- 210000005036 nerve Anatomy 0.000 claims 1
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 claims 1
- 229960002930 sirolimus Drugs 0.000 claims 1
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015059041A JP6541124B2 (ja) | 2015-03-23 | 2015-03-23 | びまん性神経線維腫用の外用薬 |
| US15/559,322 US10117857B2 (en) | 2015-03-23 | 2016-03-09 | External medicine for diffuse plexiform neurofibroma |
| ES16768422T ES2827953T3 (es) | 2015-03-23 | 2016-03-09 | Medicamento externo para neurofibroma plexiforme difuso |
| EP16768422.4A EP3275441B1 (en) | 2015-03-23 | 2016-03-09 | External medicine for diffuse plexiform neurofibroma |
| PCT/JP2016/057330 WO2016152519A1 (ja) | 2015-03-23 | 2016-03-09 | びまん性神経線維腫用の外用薬 |
| HK18110308.6A HK1250917A1 (zh) | 2015-03-23 | 2016-03-09 | 弥漫性神经纤维瘤用的外用药 |
| CN201680030048.4A CN107708694A (zh) | 2015-03-23 | 2016-03-09 | 弥漫性神经纤维瘤用的外用药 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015059041A JP6541124B2 (ja) | 2015-03-23 | 2015-03-23 | びまん性神経線維腫用の外用薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016175884A JP2016175884A (ja) | 2016-10-06 |
| JP2016175884A5 true JP2016175884A5 (enExample) | 2018-04-26 |
| JP6541124B2 JP6541124B2 (ja) | 2019-07-10 |
Family
ID=56978382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015059041A Expired - Fee Related JP6541124B2 (ja) | 2015-03-23 | 2015-03-23 | びまん性神経線維腫用の外用薬 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10117857B2 (enExample) |
| EP (1) | EP3275441B1 (enExample) |
| JP (1) | JP6541124B2 (enExample) |
| CN (1) | CN107708694A (enExample) |
| ES (1) | ES2827953T3 (enExample) |
| HK (1) | HK1250917A1 (enExample) |
| WO (1) | WO2016152519A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3932487A4 (en) * | 2019-02-27 | 2022-11-02 | Osaka University | EXTERNAL PREPARATION FOR THE TREATMENT OF VASCULAR ANOMALIES |
| AU2020365665A1 (en) * | 2019-10-16 | 2022-04-14 | Osaka University | External preparation for treating epilepsy or autism spectrum disorder |
| CN113332228B (zh) * | 2021-04-29 | 2023-03-31 | 杭州中美华东制药有限公司 | 一种西罗莫司凝胶制剂 |
| DE102023119976A1 (de) * | 2023-07-27 | 2025-01-30 | Nobelpharma Co., Ltd. | Rapamycin-haltige pharmazeutische zusammensetzung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060160837A1 (en) * | 2004-12-29 | 2006-07-20 | The Brigham And Women's Hospital, Inc. | Rapamycin compounds in the treatment of neurofibromatosis type 1 |
| MX2007009335A (es) * | 2005-02-02 | 2007-12-07 | Nexgenix Pharmaceuticals L L C | Tratamiento local de neurofibromas. |
| PT1983984T (pt) * | 2006-02-02 | 2018-06-14 | Novartis Ag | Tratamento da esclerosa tuberosa |
| WO2009023877A2 (en) * | 2007-08-16 | 2009-02-19 | Macusight, Inc. | Formulations for treatment of ocular diseases or conditions |
| US20130317053A1 (en) * | 2011-01-31 | 2013-11-28 | Osaka University | Externally-used drug for treating skin disorder and method for producing same |
-
2015
- 2015-03-23 JP JP2015059041A patent/JP6541124B2/ja not_active Expired - Fee Related
-
2016
- 2016-03-09 US US15/559,322 patent/US10117857B2/en not_active Expired - Fee Related
- 2016-03-09 EP EP16768422.4A patent/EP3275441B1/en not_active Not-in-force
- 2016-03-09 ES ES16768422T patent/ES2827953T3/es active Active
- 2016-03-09 CN CN201680030048.4A patent/CN107708694A/zh active Pending
- 2016-03-09 HK HK18110308.6A patent/HK1250917A1/zh unknown
- 2016-03-09 WO PCT/JP2016/057330 patent/WO2016152519A1/ja not_active Ceased
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