ES2827953T3 - Medicamento externo para neurofibroma plexiforme difuso - Google Patents

Medicamento externo para neurofibroma plexiforme difuso Download PDF

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Publication number
ES2827953T3
ES2827953T3 ES16768422T ES16768422T ES2827953T3 ES 2827953 T3 ES2827953 T3 ES 2827953T3 ES 16768422 T ES16768422 T ES 16768422T ES 16768422 T ES16768422 T ES 16768422T ES 2827953 T3 ES2827953 T3 ES 2827953T3
Authority
ES
Spain
Prior art keywords
weight
sirolimus
external
concentration
external drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES16768422T
Other languages
English (en)
Spanish (es)
Inventor
Mari Kaneda
Ichiro Katayama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
The University of Osaka
Original Assignee
Osaka University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osaka University NUC filed Critical Osaka University NUC
Application granted granted Critical
Publication of ES2827953T3 publication Critical patent/ES2827953T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES16768422T 2015-03-23 2016-03-09 Medicamento externo para neurofibroma plexiforme difuso Active ES2827953T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015059041A JP6541124B2 (ja) 2015-03-23 2015-03-23 びまん性神経線維腫用の外用薬
PCT/JP2016/057330 WO2016152519A1 (ja) 2015-03-23 2016-03-09 びまん性神経線維腫用の外用薬

Publications (1)

Publication Number Publication Date
ES2827953T3 true ES2827953T3 (es) 2021-05-25

Family

ID=56978382

Family Applications (1)

Application Number Title Priority Date Filing Date
ES16768422T Active ES2827953T3 (es) 2015-03-23 2016-03-09 Medicamento externo para neurofibroma plexiforme difuso

Country Status (7)

Country Link
US (1) US10117857B2 (enExample)
EP (1) EP3275441B1 (enExample)
JP (1) JP6541124B2 (enExample)
CN (1) CN107708694A (enExample)
ES (1) ES2827953T3 (enExample)
HK (1) HK1250917A1 (enExample)
WO (1) WO2016152519A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020175131A1 (ja) * 2019-02-27 2020-09-03 国立大学法人大阪大学 脈管異常治療用外用剤
EP4046637A4 (en) * 2019-10-16 2023-11-01 Osaka University EXTERNAL PREPARATION FOR THE TREATMENT OF EPILEPSY OR AN AUTISTIC SPECTRUM DISORDER
CN113332228B (zh) * 2021-04-29 2023-03-31 杭州中美华东制药有限公司 一种西罗莫司凝胶制剂
DE102023119976A1 (de) * 2023-07-27 2025-01-30 Nobelpharma Co., Ltd. Rapamycin-haltige pharmazeutische zusammensetzung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006071966A2 (en) * 2004-12-29 2006-07-06 The Brigham And Women's Hospital, Inc. Rapamycin compounds in the treatment of neurofibromatosis type 1
WO2006083979A2 (en) * 2005-02-02 2006-08-10 Nexgenix Pharmaceuticals, L.L.C. Local treatment of neurofibromas
KR20140016439A (ko) 2006-02-02 2014-02-07 노파르티스 아게 결절성 경화증의 치료
EP2187743B1 (en) * 2007-08-16 2014-07-30 Santen Pharmaceutical Co., Ltd Rapamycin formulations for treatment of age related macular degeneration
JP5652795B2 (ja) * 2011-01-31 2015-01-14 国立大学法人大阪大学 皮膚疾患を処置するための外用薬およびその製造方法

Also Published As

Publication number Publication date
US20180110759A1 (en) 2018-04-26
JP6541124B2 (ja) 2019-07-10
EP3275441B1 (en) 2020-08-12
HK1250917A1 (zh) 2019-01-18
CN107708694A (zh) 2018-02-16
WO2016152519A1 (ja) 2016-09-29
JP2016175884A (ja) 2016-10-06
EP3275441A1 (en) 2018-01-31
US10117857B2 (en) 2018-11-06
EP3275441A4 (en) 2019-01-16

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