US206877A
(en)
*
|
|
1878-08-13 |
|
Improvement in paper-pulp washers |
JPS5328173A
(en)
|
1976-08-06 |
1978-03-16 |
Zenyaku Kogyo Kk |
Novel phenylmethanenitro compound and its preparation
|
US4138397A
(en)
|
1978-02-27 |
1979-02-06 |
Richardson-Merrell Inc. |
6-(2,3-Dihydro-5-benzofuranyl)acetamido penicillin derivatives
|
GB8524157D0
(en)
|
1984-10-19 |
1985-11-06 |
Ici America Inc |
Heterocyclic amides
|
JPS61103861A
(ja)
|
1984-10-27 |
1986-05-22 |
Nitto Kasei Kk |
アリ−ル置換シアン酢酸エステルの製造方法
|
US5304121A
(en)
|
1990-12-28 |
1994-04-19 |
Boston Scientific Corporation |
Drug delivery system making use of a hydrogel polymer coating
|
US5886026A
(en)
|
1993-07-19 |
1999-03-23 |
Angiotech Pharmaceuticals Inc. |
Anti-angiogenic compositions and methods of use
|
GB9317764D0
(en)
|
1993-08-26 |
1993-10-13 |
Pfizer Ltd |
Therapeutic compound
|
US5510379A
(en)
|
1994-12-19 |
1996-04-23 |
Warner-Lambert Company |
Sulfonate ACAT inhibitors
|
US6099562A
(en)
|
1996-06-13 |
2000-08-08 |
Schneider (Usa) Inc. |
Drug coating with topcoat
|
JPH10213820A
(ja)
|
1997-01-31 |
1998-08-11 |
Canon Inc |
液晶素子及び液晶装置
|
WO1998047868A1
(en)
|
1997-04-18 |
1998-10-29 |
Smithkline Beecham Plc |
Heterocycle-containing urea derivatives as 5ht1a, 5ht1b and 5ht1d receptor antagonists
|
JP2002504916A
(ja)
|
1997-06-21 |
2002-02-12 |
ロシュ ダイアグノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング |
抗転移及び抗腫瘍活性を有するバルビツール酸誘導体
|
ES2287971T3
(es)
|
1997-08-11 |
2007-12-16 |
Pfizer Products Inc. |
Dispersiones farmaceuticas solidas con biodisponibilidad incrementada.
|
US20020017295A1
(en)
|
2000-07-07 |
2002-02-14 |
Weers Jeffry G. |
Phospholipid-based powders for inhalation
|
ATE249219T1
(de)
|
1997-12-11 |
2003-09-15 |
Iaf Biochem Int |
Antivirale verbindungen
|
US6426331B1
(en)
|
1998-07-08 |
2002-07-30 |
Tularik Inc. |
Inhibitors of STAT function
|
AUPP609198A0
(en)
|
1998-09-22 |
1998-10-15 |
Curtin University Of Technology |
Use of non-peptidyl compounds for the treatment of insulin related ailments
|
ATE277905T1
(de)
|
1999-02-24 |
2004-10-15 |
Hoffmann La Roche |
4-phenylpyridinderivate und deren verwendung als nk-1 rezeptorantagonisten
|
JP2003509430A
(ja)
|
1999-09-10 |
2003-03-11 |
ノボ ノルディスク アクティーゼルスカブ |
プロテインチロシンホスファターゼ(ptpアーゼ)のモジュレーター
|
AU6985200A
(en)
|
1999-09-10 |
2001-04-17 |
Novo Nordisk A/S |
Modulators of protein tyrosine phosphatases (ptpases)
|
AUPQ288499A0
(en)
|
1999-09-16 |
1999-10-07 |
Biota Scientific Management Pty Ltd |
Antiviral agents
|
US6514964B1
(en)
|
1999-09-27 |
2003-02-04 |
Amgen Inc. |
Fused cycloheptane and fused azacycloheptane compounds and their methods of use
|
IT1315267B1
(it)
|
1999-12-23 |
2003-02-03 |
Novuspharma Spa |
Derivati di 2-(1h-indol-3-il)-2-oxo-acetammidi ad attivita'antitumorale
|
TWI284639B
(en)
|
2000-01-24 |
2007-08-01 |
Shionogi & Co |
A compound having thrombopoietin receptor agonistic effect
|
JP2003520042A
(ja)
|
2000-01-24 |
2003-07-02 |
アイシス・ファーマシューティカルス・インコーポレーテッド |
誘導性一酸化窒素シンターゼ発現のアンチセンスモジュレーション
|
DE10038019A1
(de)
|
2000-08-04 |
2002-02-14 |
Bayer Ag |
Substituierte Triazolopyrid(az)ine
|
US6777400B2
(en)
|
2000-08-05 |
2004-08-17 |
Smithkline Beecham Corporation |
Anti-inflammatory androstane derivative compositions
|
US6562989B2
(en)
|
2000-08-07 |
2003-05-13 |
Yale University |
Catalyst for aromatic C—O, C—N, and C—C bond formation
|
TWI259180B
(en)
|
2000-08-08 |
2006-08-01 |
Hoffmann La Roche |
4-Phenyl-pyridine derivatives
|
AR030357A1
(es)
|
2000-08-18 |
2003-08-20 |
Lundbeck & Co As H |
Derivados 4 -, 5 -, 6 - y 7-indol
|
ATE399766T1
(de)
|
2000-10-20 |
2008-07-15 |
Eisai R&D Man Co Ltd |
Stickstoff enthaltende aromatische heterozyklen
|
EP1217000A1
(en)
|
2000-12-23 |
2002-06-26 |
Aventis Pharma Deutschland GmbH |
Inhibitors of factor Xa and factor VIIa
|
GB0102109D0
(en)
|
2001-01-26 |
2001-03-14 |
Syngenta Ltd |
Chemical process
|
US20100074949A1
(en)
|
2008-08-13 |
2010-03-25 |
William Rowe |
Pharmaceutical composition and administration thereof
|
EP1383799A4
(en)
|
2001-04-10 |
2008-08-06 |
Transtech Pharma Inc |
PROBES, SYSTEMS AND METHODS FOR DISCOVERING MEDICAMENTS
|
CA2440842A1
(en)
|
2001-04-16 |
2002-10-24 |
Eisai Co., Ltd. |
Novel 1h-indazole compounds
|
MXPA03011707A
(es)
|
2001-06-28 |
2004-03-19 |
Pfizer Prod Inc |
Compuestos heterobiciclicos sustituidos con triamida.
|
WO2003007945A1
(en)
|
2001-07-20 |
2003-01-30 |
Boehringer Ingelheim (Canada) Ltd. |
Viral polymerase inhibitors
|
AUPR738301A0
(en)
|
2001-08-30 |
2001-09-20 |
Starpharma Limited |
Chemotherapeutic agents
|
JP4343690B2
(ja)
|
2001-11-13 |
2009-10-14 |
メルク フロスト カナダ リミテツド |
プロテアーゼ阻害薬としてのシアノアルキルアミノ誘導体
|
ES2234451T1
(es)
|
2001-11-14 |
2005-07-01 |
Teva Pharmaceutical Industries Ltd. |
Formas cristalinas y amorfas de losartan potasio y procedimiento para su preparacion.
|
WO2003055482A1
(en)
|
2001-12-21 |
2003-07-10 |
Novo Nordisk A/S |
Amide derivatives as gk activators
|
US20030158188A1
(en)
|
2002-02-20 |
2003-08-21 |
Chih-Hung Lee |
Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
|
US7074805B2
(en)
|
2002-02-20 |
2006-07-11 |
Abbott Laboratories |
Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
|
WO2003093498A1
(en)
|
2002-04-29 |
2003-11-13 |
The Ohio State University |
Inhibition of protein tyrosine phosphatases and sh2 domains by a neutral phosphotyrosine mimetic
|
EP1531815B1
(en)
|
2002-06-27 |
2014-09-24 |
Novo Nordisk A/S |
Glucokinase activators
|
AU2003252478A1
(en)
|
2002-07-10 |
2004-02-02 |
Ono Pharmaceutical Co., Ltd. |
Ccr4 antagonist and medicinal use thereof
|
TWI244393B
(en)
|
2002-08-06 |
2005-12-01 |
Idenix Pharmaceuticals Inc |
Crystalline and amorphous forms of beta-L-2'-deoxythymidine
|
US20060083784A1
(en)
|
2002-08-07 |
2006-04-20 |
Smithkline Beecham Corporation |
Amorphous pharmaceutical compositions
|
JPWO2004026873A1
(ja)
|
2002-09-18 |
2006-01-19 |
小野薬品工業株式会社 |
トリアザスピロ[5.5]ウンデカン誘導体およびそれらを有効成分とする薬剤
|
CA2500498C
(en)
|
2002-09-30 |
2012-08-21 |
The Regents Of The University Of California |
Cystic fibrosis transmembrane conductance regulator protein inhibitors and uses thereof
|
JP2004131393A
(ja)
|
2002-10-08 |
2004-04-30 |
Kowa Co |
易溶出性製剤
|
JP2006505571A
(ja)
|
2002-10-15 |
2006-02-16 |
リゲル ファーマシューテイカルズ、インコーポレイテッド |
置換されたインドール及びhcv阻害剤としてのその使用
|
FR2846327B1
(fr)
|
2002-10-25 |
2006-03-24 |
Merck Sante Sas |
Derives de n-benzodioxolyl, n-benzodioxanyl et n-benzodioxepinyl arylcarboxamides utilisables dans le traitement de dyslipidemies et compositions pharmaceutiques les contenant.
|
US7622592B2
(en)
|
2002-11-01 |
2009-11-24 |
Merck & Co., Inc. |
Carbonylamino-benzimidazole derivatives as androgen receptor modulators
|
DE10251019A1
(de)
|
2002-11-02 |
2004-05-19 |
Aventis Pharma Deutschland Gmbh |
Neue Pyrimidin-4,6-dicarbonsäurediamide zur selektiven Inhibierung von Kollagenasen
|
MXPA05004365A
(es)
|
2002-11-02 |
2005-07-05 |
Aventis Pharma Gmbh |
Nuevas diamidas del acido pirimidin -4, 6 - dicarboxilico para la inhibicion selectiva de colagenasas.
|
US20040146941A1
(en)
|
2002-11-04 |
2004-07-29 |
Biliang Zhang |
Chemical encoding technology for combinatorial synthesis
|
WO2004056744A1
(en)
|
2002-12-23 |
2004-07-08 |
Janssen Pharmaceutica N.V. |
Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
|
DE10300017A1
(de)
|
2003-01-03 |
2004-07-15 |
Aventis Pharma Deutschland Gmbh |
Selektive MMP 13 Inhibitoren
|
EA011808B1
(ru)
|
2003-01-08 |
2009-06-30 |
Новартис Вэксинес Энд Дайэгностикс, Инк. |
Антибактериальные агенты
|
WO2004089470A2
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
New amide derivatives and pharmaceutical use thereof
|
US6933311B2
(en)
|
2003-02-11 |
2005-08-23 |
Abbott Laboratories |
Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
|
ATE450533T1
(de)
|
2003-02-14 |
2009-12-15 |
Glaxo Group Ltd |
Carboxamidderivate
|
DE10306941A1
(de)
|
2003-02-18 |
2004-08-26 |
Merck Patent Gmbh |
Benzofuranoxyethylamine
|
EP1601657A1
(en)
|
2003-03-12 |
2005-12-07 |
Vertex Pharmaceuticals Incorporated |
Pyrazole modulators of atp-binding cassette transporters
|
US20050164951A1
(en)
|
2003-04-03 |
2005-07-28 |
The Regents Of The University Of California |
Inhibitors for the soluble epoxide hydrolase
|
JP4705015B2
(ja)
|
2003-04-03 |
2011-06-22 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
カルボニル化合物
|
DE10315377A1
(de)
|
2003-04-03 |
2004-10-14 |
Merck Patent Gmbh |
Carbonylverbindungen
|
ES2926542T3
(es)
|
2003-04-11 |
2022-10-26 |
Ptc Therapeutics Inc |
Compuestos de ácido 1,2,4-oxadiazol benzoico y su uso para supresión de mutaciones finalizadoras y el tratamiento de enfermedades
|
WO2004110352A2
(en)
|
2003-05-16 |
2004-12-23 |
The Regents Of The University Of California |
Compounds having activity in increasing ion transport by mutant-cftr and uses thereof
|
WO2004111014A1
(en)
|
2003-06-06 |
2004-12-23 |
Vertex Pharmaceuticals Incorporated |
Pyrimidine derivatives as modulators of atp-binding cassette transporters
|
CA2530075C
(en)
|
2003-06-27 |
2012-08-21 |
Harvey Pollard |
Amphiphilic pyridinium compounds, method of making and use thereof
|
US20050113576A1
(en)
|
2003-08-05 |
2005-05-26 |
Chih-Hung Lee |
Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
|
US7834008B2
(en)
|
2003-08-15 |
2010-11-16 |
H. Lundbeck A/S |
Cyclopropyl derivatives as NK3 receptor antagonists
|
ZA200602755B
(en)
|
2003-09-06 |
2007-06-27 |
Vertex Pharma |
Modulators of ATP-binding cassette transporters
|
US20050070718A1
(en)
|
2003-09-30 |
2005-03-31 |
Abbott Gmbh & Co. Kg |
Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
|
WO2005035514A2
(en)
|
2003-10-08 |
2005-04-21 |
Vertex Pharmaceuticals Incorporated |
Modulators of atp-binding cassette transporters containing cycloalkyl or pyranyl groups
|
WO2005037802A1
(ja)
|
2003-10-16 |
2005-04-28 |
Sankyo Company, Limited |
5-アリールピリミジン誘導体
|
WO2005040135A1
(ja)
|
2003-10-24 |
2005-05-06 |
Ono Pharmaceutical Co., Ltd. |
抗ストレス薬およびその医薬用途
|
AU2004290581B2
(en)
|
2003-11-14 |
2011-07-14 |
Vertex Pharmaceuticals Incorporated |
Thiazoles and oxazoles useful as modulators of ATP-Binding Cassette transporters
|
GB0330043D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them
|
CN1938279B
(zh)
|
2004-01-30 |
2011-09-14 |
沃泰克斯药物股份有限公司 |
Atp-结合弹夹转运蛋白调控剂
|
US7977322B2
(en)
|
2004-08-20 |
2011-07-12 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-binding cassette transporters
|
JP4889505B2
(ja)
|
2004-02-02 |
2012-03-07 |
アンブレツクス・インコーポレイテツド |
被修飾されたヒト成長ホルモンポリペプチドおよびこれらの使用
|
EA011074B1
(ru)
|
2004-03-30 |
2008-12-30 |
Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния |
Гидразидсодержащие соединения - ингибиторы cftr и их применение
|
US20050222271A1
(en)
|
2004-03-31 |
2005-10-06 |
Le Huang |
Novel amorphous form of memantine hydrochloride
|
FR2868417B1
(fr)
|
2004-04-02 |
2006-06-23 |
Rhodia Chimie Sa |
Procede de formation d'une liaison carbone-carbone
|
EP1766062A4
(en)
|
2004-06-01 |
2008-07-09 |
Tm Bioscience Corp |
METHOD FOR DETECTING MUTATIONS ASSOCIATED WITH CYSTIC FIBROSIS
|
AU2005251745A1
(en)
|
2004-06-04 |
2005-12-22 |
The Regents Of The University Of California |
Compounds having activity in increasing ion transport by mutant-CFTR and uses thereof
|
US20140343098A1
(en)
|
2004-06-24 |
2014-11-20 |
Vertex Pharmaceuticals Incorporated |
Modulators of atp-binding cassette transporters
|
CN101006076B
(zh)
|
2004-06-24 |
2010-09-29 |
沃泰克斯药物股份有限公司 |
Atp-结合弹夹转运蛋白的调控剂
|
US8354427B2
(en)
|
2004-06-24 |
2013-01-15 |
Vertex Pharmaceutical Incorporated |
Modulators of ATP-binding cassette transporters
|
WO2006014427A1
(en)
|
2004-07-02 |
2006-02-09 |
Advancis Pharmaceutical Corporation |
Tablet for pulsed delivery
|
GB0416730D0
(en)
|
2004-07-27 |
2004-09-01 |
Novartis Ag |
Organic compounds
|
MX2007001215A
(es)
|
2004-08-06 |
2007-04-17 |
Otsuka Pharma Co Ltd |
Compuestos aromaticos.
|
DE102004047254A1
(de)
|
2004-09-29 |
2006-04-13 |
Merck Patent Gmbh |
Carbonylverbindungen
|
EP1799212A2
(en)
|
2004-10-13 |
2007-06-27 |
PTC Therapeutics, Inc. |
Compounds for nonsense suppression, and methods for their use
|
EP1814875A4
(en)
|
2004-10-20 |
2010-02-17 |
Univ California |
IMPROVED INHIBITORS OF SOLUBLE HYDROLASE EPOXYDE
|
JPWO2006057448A1
(ja)
|
2004-11-26 |
2008-06-05 |
武田薬品工業株式会社 |
アリールアルカン酸誘導体
|
EP1676834A1
(en)
*
|
2004-12-30 |
2006-07-05 |
Sanofi-Aventis Deutschland GmbH |
Fused bicyclic carboxamide derivates for use as CXCR2 inhibitors in the treatment of inflammation
|
AU2006216170B2
(en)
|
2005-02-25 |
2012-02-09 |
Ono Pharmaceutical Co., Ltd. |
Indole compound and use thereof
|
EP2363128B1
(en)
|
2005-03-11 |
2016-02-17 |
Vertex Pharmaceuticals Incorporated |
Indole modulators of ATP-binding cassette transporters
|
CA2600869A1
(en)
|
2005-03-18 |
2006-09-28 |
The Regents Of The University Of California |
Compounds having activity in correcting mutant-cftr processing and uses thereof
|
US20100120789A1
(en)
|
2005-03-24 |
2010-05-13 |
Nigel Vicker |
Compound
|
GB0506133D0
(en)
|
2005-03-24 |
2005-05-04 |
Sterix Ltd |
Compound
|
US7402596B2
(en)
|
2005-03-24 |
2008-07-22 |
Renovis, Inc. |
Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
|
EP1864978A4
(en)
|
2005-03-28 |
2009-07-01 |
Toyama Chemical Co Ltd |
PROCESS FOR PRODUCING 1- (3- (2- (1-BENZOTHIOPHEN-5-YL) -ETHOXY) PROPYL) AZETIDIN-3-OL OR ITS SALTS
|
JP2006282534A
(ja)
|
2005-03-31 |
2006-10-19 |
Fuji Photo Film Co Ltd |
アミド類の製造方法
|
CA2603402C
(en)
|
2005-04-08 |
2017-10-31 |
Ptc Therapeutics, Inc. |
Compositions of an orally active 1,2,4-oxadiazole for nonsense mutation suppression therapy
|
JP2008537953A
(ja)
|
2005-04-15 |
2008-10-02 |
エラン ファーマシューティカルズ,インコーポレイテッド |
ブラジキニンb1受容体拮抗作用に有用な新規化合物
|
AU2006251624A1
(en)
|
2005-05-24 |
2006-11-30 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding cassette transporters
|
WO2007021982A2
(en)
|
2005-08-11 |
2007-02-22 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator
|
CN101287732A
(zh)
|
2005-08-11 |
2008-10-15 |
沃泰克斯药物股份有限公司 |
囊性纤维化跨膜电导调节剂的调控剂
|
ES2414434T3
(es)
|
2005-08-29 |
2013-07-19 |
Sanofi-Aventis U.S. Llc |
Dispersiones sólidas amorfas de 7-cloro-N,N,5-trimetil-4-oxo-3-fenil-3,5-dihidro-4H-piridazino[4,5-b]indol-1-acetamida
|
CN101312722A
(zh)
|
2005-10-06 |
2008-11-26 |
沃泰克斯药物股份有限公司 |
Atp-结合弹夹转运蛋白的调控剂
|
EP1942732A2
(en)
|
2005-11-02 |
2008-07-16 |
Cytokinetics, Inc. |
Certain chemical entities, compositions, and methods
|
US20120232059A1
(en)
|
2005-11-08 |
2012-09-13 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette Transporters
|
SI1945632T1
(sl)
|
2005-11-08 |
2014-03-31 |
Vertex Pharmaceuticals Incorporated |
Heterocikliäśni modulatorji za prenaĺ alce z atp-vezavno kaseto
|
GB0525144D0
(en)
|
2005-12-09 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
MX2008008277A
(es)
|
2005-12-21 |
2009-03-04 |
Janssen Pharmaceutica Nv |
Triazolopiridazinas como moduladores de tirosina cinasa.
|
JP2009521468A
(ja)
|
2005-12-24 |
2009-06-04 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Abc輸送体の調節因子としてのキノリン−4−オン誘導体
|
WO2007075946A1
(en)
|
2005-12-27 |
2007-07-05 |
Vertex Pharmaceuticals Incorporated |
Compounds useful in cftr assays and methods therewith
|
JP5409010B2
(ja)
|
2005-12-28 |
2014-02-05 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
N−[2,4−ビス(1,1−ジメチルエチル)−5−ヒドロキシフェニル]−1,4−ジヒドロ−4−オキソキノリン−3−カルボキサミドの固体形態
|
US7671221B2
(en)
|
2005-12-28 |
2010-03-02 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette transporters
|
CN103214450B
(zh)
|
2005-12-28 |
2016-10-05 |
弗特克斯药品有限公司 |
作为atp-结合盒转运蛋白调节剂的1-(苯并[d][1,3]间二氧杂环戊烯-5-基)-n-(苯基)环丙烷-甲酰胺衍生物
|
AR059826A1
(es)
|
2006-03-13 |
2008-04-30 |
Univ California |
Inhibidores de urea conformacionalmente restringidos de epoxido hidrolasa soluble
|
MX2008011976A
(es)
|
2006-03-20 |
2009-04-07 |
Vertex Pharma |
Composiciones farmaceuticas.
|
CN101494979A
(zh)
|
2006-03-20 |
2009-07-29 |
沃泰克斯药物股份有限公司 |
药物组合物
|
AU2007230991A1
(en)
|
2006-03-22 |
2007-10-04 |
Syndexa Pharmaceuticals Corporation |
Compounds and methods for treatment of disorders associated with ER stress
|
SG170819A1
(en)
*
|
2006-03-30 |
2011-05-30 |
Ptc Therapeutics Inc |
Methods for the production of functional protein from dna having a nonsense mutation and the treatment of disorders associated therewith
|
US7645789B2
(en)
|
2006-04-07 |
2010-01-12 |
Vertex Pharmaceuticals Incorporated |
Indole derivatives as CFTR modulators
|
HUE036165T2
(hu)
|
2006-04-07 |
2018-06-28 |
Vertex Pharma |
ATP-kötõ kazetta transzportereinek modulátorai
|
US10022352B2
(en)
|
2006-04-07 |
2018-07-17 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-binding cassette transporters
|
CA2652072A1
(en)
|
2006-05-12 |
2007-11-22 |
Vertex Pharmaceuticals Incorporated |
Compositions of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
|
WO2007146712A2
(en)
|
2006-06-09 |
2007-12-21 |
Kemia, Inc. |
Therapy using cytokine inhibitors
|
WO2008020227A2
(en)
|
2006-08-17 |
2008-02-21 |
Astrazeneca Ab |
Antibacterial pyrrolecarboxamides
|
WO2008029152A2
(en)
|
2006-09-08 |
2008-03-13 |
Summit Corporation Plc |
Treatment of duchenne muscular dystrophy
|
WO2008029168A2
(en)
|
2006-09-08 |
2008-03-13 |
Summit Corporation Plc |
Treatment of duchenne muscular dystrophy
|
DK2081937T3
(da)
|
2006-10-23 |
2012-10-01 |
Sgx Pharmaceuticals Inc |
Triazolopyridazin-proteinkinasemodulatorer
|
NZ576642A
(en)
|
2006-11-03 |
2011-11-25 |
Vertex Pharma |
Azaindole derivatives as cftr modulators
|
US8563573B2
(en)
|
2007-11-02 |
2013-10-22 |
Vertex Pharmaceuticals Incorporated |
Azaindole derivatives as CFTR modulators
|
US7754739B2
(en)
|
2007-05-09 |
2010-07-13 |
Vertex Pharmaceuticals Incorporated |
Modulators of CFTR
|
US20080132560A1
(en)
|
2006-11-21 |
2008-06-05 |
San-Laung Chow |
Solid dispersion composition
|
WO2008065732A1
(fr)
|
2006-11-27 |
2008-06-05 |
Nippon Polyurethane Industry Co., Ltd. |
Procédé de production d'un mélange à base d'isocyanate modifié contenant une liaison allophanate et une liaison isocyanurate
|
US20080260820A1
(en)
|
2007-04-19 |
2008-10-23 |
Gilles Borrelly |
Oral dosage formulations of protease-resistant polypeptides
|
JP5497633B2
(ja)
|
2007-05-09 |
2014-05-21 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Cftrのモジュレーター
|
ES2548292T3
(es)
|
2007-05-25 |
2015-10-15 |
Vertex Pharmaceuticals Incorporated |
Moduladores del regulador de la conductancia transmembrana de la fibrosis quística
|
US8557823B2
(en)
|
2007-06-18 |
2013-10-15 |
Advanced Cancer Therapeutics, Llc |
Family of PFKFB3 inhibitors with anti-neoplastic activities
|
EP2167058B1
(en)
|
2007-06-18 |
2015-08-12 |
University Of Louisville Research Foundation, Inc. |
Family of pfkfb3 inhibitors with anti-neoplastic activities
|
NZ582057A
(en)
|
2007-07-19 |
2012-03-30 |
Lundbeck & Co As H |
5-membered heterocyclic amides and related compounds
|
US20110177999A1
(en)
|
2007-08-09 |
2011-07-21 |
Vertex Pharmaceuticals Incorporated |
Therapeutic Combinations Useful in Treating CFTR Related Diseases
|
CA2696298C
(en)
|
2007-08-24 |
2016-09-06 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator
|
WO2009036412A1
(en)
|
2007-09-14 |
2009-03-19 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator
|
AU2008301907B2
(en)
|
2007-09-14 |
2014-02-20 |
Vertex Pharmaceuticals Incorporated |
Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
|
KR20100095430A
(ko)
|
2007-11-02 |
2010-08-30 |
메틸진 인크. |
히스톤 탈아세틸화효소의 저해물질
|
EP2217572B1
(en)
|
2007-11-16 |
2013-11-06 |
Vertex Pharmaceuticals Incorporated |
Isoquinoline modulators of atp-binding cassette transporters
|
KR101576695B1
(ko)
|
2007-11-22 |
2015-12-10 |
젠야쿠코교가부시키가이샤 |
복소환식 화합물의 비정질체, 이를 포함하는 고체 분산체, 약제 및 그 제조법
|
EP2237768A2
(en)
|
2007-12-07 |
2010-10-13 |
Vertex Pharmaceuticals Incorporated |
Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
|
WO2009076142A2
(en)
|
2007-12-07 |
2009-06-18 |
Vertex Pharmaceuticals Incorporated |
Processes for producing cycloalkylcarboxiamido-pyridine benzoic acids
|
WO2009073757A1
(en)
|
2007-12-07 |
2009-06-11 |
Vertex Pharmaceuticals Incorporated |
Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3] dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid
|
US20100036130A1
(en)
|
2007-12-07 |
2010-02-11 |
Vertex Pharmaceuticals Incorporated |
Processes for producing cycloalkylcarboxamido-pyridine benzoic acids
|
CN101925603B
(zh)
|
2007-12-13 |
2013-12-04 |
沃泰克斯药物股份有限公司 |
囊性纤维化跨膜通道调节因子的调节剂
|
US20090247521A1
(en)
|
2007-12-28 |
2009-10-01 |
Arete Therapeutics, Inc. |
Soluble epoxide hydrolase inhibitors for the treatment of endothelial dysfunction
|
CA3039943C
(en)
|
2008-02-28 |
2021-07-13 |
Vertex Pharmaceuticals Incorporated |
Heteroaryl derivatives as cftr modulators
|
SI2615085T1
(sl)
|
2008-03-31 |
2015-11-30 |
Vertex Pharmaceuticals Incorporated |
Piridilni derivati kot cftr-modulatorji
|
EP2274280A2
(en)
|
2008-04-16 |
2011-01-19 |
Biolipox AB |
Bis-aryl compounds for use as medicaments
|
WO2009129501A1
(en)
|
2008-04-18 |
2009-10-22 |
Arete Therapeutics, Inc. |
Use of soluble epoxide hydrolase inhibitors in the treatment of smooth muscle disorders
|
WO2009132253A1
(en)
|
2008-04-24 |
2009-10-29 |
Bristol-Myers Squibb Company |
Use of epothelone d in treating tau-associated diseases including alzheimer's disease
|
US20110112193A1
(en)
|
2008-05-14 |
2011-05-12 |
Peter Nilsson |
Bis-aryl compounds for use as medicaments
|
US9447049B2
(en)
|
2010-03-01 |
2016-09-20 |
University Of Tennessee Research Foundation |
Compounds for treatment of cancer
|
US8822513B2
(en)
|
2010-03-01 |
2014-09-02 |
Gtx, Inc. |
Compounds for treatment of cancer
|
US20100256184A1
(en)
|
2008-08-13 |
2010-10-07 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical composition and administrations thereof
|
WO2010019239A2
(en)
|
2008-08-13 |
2010-02-18 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical composition and administrations thereof
|
WO2010028159A2
(en)
|
2008-09-04 |
2010-03-11 |
Georgetown University |
Transition metal-catalyzed c-h amination using unactivated amines
|
TW201011009A
(en)
|
2008-09-15 |
2010-03-16 |
Priaxon Ag |
Novel pyrrolidin-2-ones
|
US8716338B2
(en)
|
2008-09-29 |
2014-05-06 |
Vertex Pharmaceuticals Incorporated |
Dosage units of 3-(6-(1-(2,2-difluorobenzo[D] [1,3] dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
|
WO2010048149A2
(en)
|
2008-10-20 |
2010-04-29 |
Kalypsys, Inc. |
Heterocyclic modulators of gpr119 for treatment of disease
|
CA2742042A1
(en)
|
2008-10-23 |
2010-04-29 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator
|
US20110257223A1
(en)
|
2008-10-23 |
2011-10-20 |
Vertex Pharmaceuticals Incorporated |
Modulators of Cystic Fibrosis Transmembrane Conductance Regulator
|
PL2358680T3
(pl)
|
2008-10-23 |
2013-08-30 |
Vertex Pharma |
Stałe postacie N-(4-(7-azabicyklo[2.2.1]heptan-7-ylo)-2-(trifluorometylo)fenylo)-4-okso-5-(trifluorometylo)-1,4-dihydrochinolino-3-karboksyamidu
|
BRPI0919930A2
(pt)
|
2008-10-23 |
2016-02-16 |
Vertex Pharma |
moduladores de regulador de condutância transmembrana de fibrose cística
|
UA104876C2
(uk)
|
2008-11-06 |
2014-03-25 |
Вертекс Фармасьютікалз Інкорпорейтед |
Модулятори atф-зв'язувальних касетних транспортерів
|
AU2008363828B2
(en)
|
2008-11-06 |
2016-09-08 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-binding cassette transporters
|
US20120165304A1
(en)
|
2008-11-27 |
2012-06-28 |
Boehringer Ingelheim International Gmbh |
6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyclohept[f]indene derivatives, pharmaceutical compositions containing these compounds, their use and processes for preparing them
|
KR20110098779A
(ko)
|
2008-12-03 |
2011-09-01 |
프레시디오 파마슈티칼스, 인코포레이티드 |
Hcv ns5a의 억제제
|
JP5699090B2
(ja)
|
2008-12-30 |
2015-04-08 |
バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated |
嚢胞性線維症膜コンダクタンス調節因子のモジュレーター
|
US8946419B2
(en)
|
2009-02-23 |
2015-02-03 |
Mallinckrodt Llc |
(+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives
|
KR20100101056A
(ko)
|
2009-03-07 |
2010-09-16 |
주식회사 메디젠텍 |
세포핵에서 세포질로의 gsk3의 이동을 억제하는 화합물을 함유하는 세포핵에서 세포질로의 gsk3 이동에 의해 발생되는 질환의 치료 또는 예방용 약학적 조성물
|
EP2821400B1
(en)
|
2009-03-20 |
2017-09-27 |
Vertex Pharmaceuticals Incorporated |
Process for making modulators of cystic fibrosis transmembrane conductance regulator
|
PL2408749T3
(pl)
|
2009-03-20 |
2018-11-30 |
Vertex Pharmaceuticals Incorporated |
Modulatory transbłonowego regulatora przewodnictwa mukowiscydozy
|
GB0905641D0
(en)
|
2009-04-01 |
2009-05-13 |
Serodus As |
Compounds
|
AU2010238361B2
(en)
|
2009-04-16 |
2015-08-06 |
Fundacion Centro Nacional De Investigaciones Oncologicas Carlos Iii |
Imidazopyrazines for use as kinase inhibitors
|
WO2011005355A1
(en)
|
2009-05-07 |
2011-01-13 |
Achaogen, Inc. |
Combinations comprising a lpxc inhibitor and an antibiotic for use in the treatment of infections caused by gram-negative bacteria
|
CA2761639C
(en)
|
2009-05-29 |
2016-06-07 |
Raqualia Pharma Inc. |
Aryl substituted carboxamide derivatives as calcium or sodium channel blockers
|
EP2264012A1
(de)
|
2009-06-03 |
2010-12-22 |
Bayer CropScience AG |
Heteroarylamidine und deren Verwendung als Fungizide
|
KR101256018B1
(ko)
|
2009-08-20 |
2013-04-18 |
한국과학기술연구원 |
단백질 키나아제 저해활성을 갖는 1,3,6-치환된 인돌 화합물
|
AR078278A1
(es)
|
2009-09-09 |
2011-10-26 |
Vifor Int Ag |
Antagonistas de la tiazol y oxazol hepcidina, composiciones farmaceuticas que los contienen y uso de los mismos para el tratamiento de anemias y enfermedades asociadas a deficiencias de hierro.
|
NZ598277A
(en)
|
2009-09-17 |
2014-03-28 |
Vertex Pharma |
Process for preparing azabicyclic compounds
|
WO2011034506A1
(en)
|
2009-09-18 |
2011-03-24 |
Nanyang Technological University |
Process of forming an amide
|
EP2813227A1
(en)
|
2009-10-22 |
2014-12-17 |
Vertex Pharmaceuticals Incorporated |
Compositions for treatment of cystic fibrosis and other chronic diseases
|
WO2011050220A1
(en)
|
2009-10-23 |
2011-04-28 |
Vertex Pharmaceuticals Incorporated |
Solid forms of n-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide
|
RU2553989C2
(ru)
|
2009-10-23 |
2015-06-20 |
Вертекс Фармасьютикалз Инкорпорейтед |
Способ получения модуляторов регулятора трансмембранной проводимости кистозного фиброза
|
WO2011094890A1
(en)
|
2010-02-02 |
2011-08-11 |
Argusina Inc. |
Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators
|
JP5879273B2
(ja)
|
2010-03-01 |
2016-03-08 |
ジーティーエックス・インコーポレイテッド |
癌を処置するための化合物
|
WO2011115892A1
(en)
|
2010-03-15 |
2011-09-22 |
Griffin Patrick R |
Modulators of the retinoic acid receptor-related orphan receptors
|
EP2547658A1
(en)
|
2010-03-19 |
2013-01-23 |
Vertex Pharmaceuticals Incorporated |
Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
|
US8247436B2
(en)
|
2010-03-19 |
2012-08-21 |
Novartis Ag |
Pyridine and pyrazine derivative for the treatment of CF
|
US8802868B2
(en)
|
2010-03-25 |
2014-08-12 |
Vertex Pharmaceuticals Incorporated |
Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
|
AU2011230508B2
(en)
*
|
2010-03-25 |
2016-04-28 |
Vertex Pharmaceuticals Incorporated |
Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihyderoxypropyl)-6-fluoro-2- (1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl) cyclopropanecarboxamide
|
CA2795748C
(en)
|
2010-04-07 |
2020-12-08 |
Vertex Pharmaceuticals Incorporated |
Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
|
CA2795804C
(en)
|
2010-04-07 |
2021-10-26 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyriodin-2-yl)benzoic acid and administration thereof
|
NZ603044A
(en)
|
2010-04-22 |
2015-08-28 |
Vertex Pharma |
Pharmaceutical compositions comprising cftr modulators and administrations thereof
|
EP2560650A1
(en)
|
2010-04-22 |
2013-02-27 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions and administrations thereof
|
AU2011242452A1
(en)
*
|
2010-04-22 |
2012-11-08 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions and administrations thereof
|
KR20130056244A
(ko)
|
2010-04-22 |
2013-05-29 |
버텍스 파마슈티칼스 인코포레이티드 |
시클로알킬카르복스아미도-인돌 화합물의 제조 방법
|
EP2386606B1
(fr)
|
2010-04-30 |
2018-03-21 |
Total Marketing Services |
Utilisation de dérivés organogelateurs dans des compositions bitumineuses pour améliorer leur résistance aux agressions chimiques
|
TW201202250A
(en)
|
2010-05-20 |
2012-01-16 |
Vertex Pharma |
Processes for producing modulators of cystic fibrosis transmembrane conductance regulator
|
EP2575814A1
(en)
|
2010-05-20 |
2013-04-10 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions and administrations thereof
|
RU2608390C2
(ru)
|
2010-05-20 |
2017-01-18 |
Семпра Фармасьютикалз, Инк. |
Способы получения макролидов и кетолидов, и промежуточных соединений для их получения
|
US8563593B2
(en)
|
2010-06-08 |
2013-10-22 |
Vertex Pharmaceuticals Incorporated |
Formulations of (R)-1-(2,2-difluorobenzo[D] [1,3] dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
|
US20120149708A1
(en)
|
2010-06-17 |
2012-06-14 |
George Mason University |
Modulators of viral transcription, and methods and compositions therewith
|
WO2012016133A2
(en)
|
2010-07-29 |
2012-02-02 |
President And Fellows Of Harvard College |
Ros1 kinase inhibitors for the treatment of glioblastoma and other p53-deficient cancers
|
UA110113C2
(xx)
|
2010-07-29 |
2015-11-25 |
|
Біциклічні азагетероциклічні карбоксаміди
|
CN103153287A
(zh)
|
2010-08-23 |
2013-06-12 |
弗特克斯药品有限公司 |
(R)-1-(2,2-二氟苯并[d][1,3]间二氧杂环戊烯-5-基)-N-(1-(2,3-二羟基丙基)-6-氟-2-(1-羟基-2-甲基丙-2-基)-1H-吲哚-5-基)环丙烷甲酰胺的药物组合物及其施用
|
AU2011293135A1
(en)
|
2010-08-27 |
2013-04-11 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical composition and administrations thereof
|
WO2012049555A1
(en)
|
2010-10-13 |
2012-04-19 |
Lupin Limited |
Spirocyclic compounds as voltage-gated sodium channel modulators
|
EP2630136A1
(en)
|
2010-10-21 |
2013-08-28 |
Universität des Saarlandes |
Selective cyp11b1 inhibitors for the treatment of cortisol dependent diseases
|
US8802700B2
(en)
|
2010-12-10 |
2014-08-12 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette transporters
|
WO2012079583A1
(en)
|
2010-12-15 |
2012-06-21 |
Aarhus Universitet |
System providing controlled delivery of gaseous co for carbonylation reactions
|
CA2827392A1
(en)
|
2011-02-24 |
2012-08-30 |
Emory University |
Noggin blocking compositions for ossification and methods related thereto
|
WO2012129562A2
(en)
|
2011-03-24 |
2012-09-27 |
The Scripps Research Institute |
Compounds and methods for inducing chondrogenesis
|
CN102731492B
(zh)
|
2011-03-30 |
2016-06-29 |
江苏恒瑞医药股份有限公司 |
环己烷类衍生物、其制备方法及其在医药上的应用
|
HUE047354T2
(hu)
|
2011-05-18 |
2020-04-28 |
Vertex Pharmaceuticals Europe Ltd |
Ivacaftor deuterizált származékai
|
US8945605B2
(en)
|
2011-06-07 |
2015-02-03 |
Parion Sciences, Inc. |
Aerosol delivery systems, compositions and methods
|
WO2013005057A1
(en)
|
2011-07-07 |
2013-01-10 |
Centro Nacional De Investigaciones Oncológicas (Cnio) |
New compounds
|
DK2753605T3
(da)
|
2011-09-09 |
2019-06-17 |
Lantheus Medical Imaging Inc |
Sammensætninger, fremgangsmåder, og systemer til syntesen og anvendelsen af billeddannelsesmidler
|
JP5886433B2
(ja)
|
2011-09-16 |
2016-03-16 |
ノバルティス アーゲー |
嚢胞性線維症処置のためのヘテロ環式化合物
|
EP2755652B1
(en)
|
2011-09-16 |
2021-06-02 |
Novartis AG |
N-substituted heterocyclyl carboxamides
|
WO2013038373A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Pyridine amide derivatives
|
WO2013038378A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Pyridine amide derivatives
|
WO2013038381A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Pyridine/pyrazine amide derivatives
|
GB201116559D0
(en)
|
2011-09-26 |
2011-11-09 |
Univ Leuven Kath |
Novel viral replication inhibitors
|
AU2012332225A1
(en)
|
2011-11-02 |
2014-05-15 |
Vertex Pharmaceuticals Incorporated |
Use of (N- [2, 4 -bis (1, 1 -dimethylethyl) - 5 - hydroxyphenyl] - 1, 4 - dihydro - 4 - oxoquinoline - 3 - ca rboxamide) for treating CFTR mediated diseases
|
US20140127901A1
(en)
|
2012-11-08 |
2014-05-08 |
Taiwan Semiconductor Manufacturing Company, Ltd. |
Low-k damage free integration scheme for copper interconnects
|
KR101985044B1
(ko)
|
2011-11-08 |
2019-05-31 |
버텍스 파마슈티칼스 인코포레이티드 |
Atp-결합 카세트 수송체의 조절제
|
WO2013086131A1
(en)
|
2011-12-06 |
2013-06-13 |
The Trustees Of The University Of Pennsylvania |
Inhibitors targeting drug-resistant influenza a
|
US8772541B2
(en)
|
2011-12-15 |
2014-07-08 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Cannabinoid receptor 2 (CB2) inverse agonists and therapeutic potential for multiple myeloma and osteoporosis bone diseases
|
EP2606726A1
(de)
|
2011-12-21 |
2013-06-26 |
Bayer CropScience AG |
N-Arylamidine-substituierte trifluoroethylsulfid-Derivate als Akarizide und Insektizide
|
CA3128556A1
(en)
|
2012-01-25 |
2013-08-01 |
Vertex Pharmaceuticals Incorporated |
Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
|
MX2014010253A
(es)
|
2012-02-27 |
2014-11-12 |
Vertex Pharma |
Composicion farmaceutica y administraciones de la misma.
|
EP2834313A1
(en)
|
2012-04-03 |
2015-02-11 |
3M Innovative Properties Company |
Crosslinkable composition comprising photobase generators
|
US8674108B2
(en)
|
2012-04-20 |
2014-03-18 |
Vertex Pharmaceuticals Incorporated |
Solid forms of N-[2,4-bis(1,1-dimethylethy)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
|
US8888905B2
(en)
|
2012-04-26 |
2014-11-18 |
Xerox Corporation |
Fast crystallizing crystalline-amorphous ink compositions and methods for making the same
|
US20130284054A1
(en)
|
2012-04-26 |
2013-10-31 |
Xerox Corporation |
Rapid solidifying crystalline-amorphous inks
|
US9528016B2
(en)
|
2012-04-26 |
2016-12-27 |
Xerox Corporation |
Phase change inks comprising crystalline amides
|
US9228101B2
(en)
|
2012-04-26 |
2016-01-05 |
Xerox Corporation |
Rapidly crystallizing phase change inks and methods for forming the same
|
CA2813472A1
(en)
|
2012-04-26 |
2013-10-26 |
Xerox Corporation |
Rapid solidifying crystalline-amorphous inks
|
JP6204977B2
(ja)
|
2012-05-25 |
2017-09-27 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
三級アミン、前記アミンを含む薬物、その使用及びその調製方法
|
GB2502624A
(en)
|
2012-06-01 |
2013-12-04 |
Univ East Anglia |
Phosphoramide and phosphoramide-based catalysts and their use in intermolecular aziridination
|
WO2013185112A1
(en)
|
2012-06-08 |
2013-12-12 |
Vertex Pharmaceuticals Incorporated |
Pharmaceuticl compositions for the treatment of cftr -mediated disorders
|
EP2859005B1
(en)
|
2012-06-08 |
2018-10-31 |
Massachusetts Institute of Technology |
Phosphine-ligated palladium sulfonate palladacycles
|
FR2992317B1
(fr)
|
2012-06-22 |
2016-05-13 |
Diverchim |
Procede de preparation de peptides chiraux
|
WO2014002106A1
(en)
|
2012-06-25 |
2014-01-03 |
Cadila Healthcare Limited |
Novel compounds for the treatment of dyslipidemia and related diseases
|
WO2014011050A1
(en)
|
2012-07-12 |
2014-01-16 |
Proqr Therapeutics B.V. |
Exon replacement with stabilized artificial rnas
|
DK3103872T3
(en)
|
2012-07-12 |
2018-10-22 |
Proqr Therapeutics Ii Bv |
OLIGONUCLEOTIDES TO MAKE A CHANGE IN THE SEQUENCE OF A TARGET RNA MOLECULE IN A LIVING CELL
|
WO2014014841A1
(en)
*
|
2012-07-16 |
2014-01-23 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions of (r)-1-(2,2-diflurorbenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide and administration thereof
|
ES2863538T3
(es)
|
2012-09-20 |
2021-10-11 |
Univ Temple |
Derivados de alquil diarilo sustituidos, métodos de preparación y usos
|
BR102012025405A2
(pt)
|
2012-10-05 |
2014-10-07 |
Univ Brasilia Fudacao |
Processo de obtenção de amidas via aminólise catalítica de ésteres e ácidos carboxílicos em líquidos iônicos
|
CN104769465A
(zh)
|
2012-10-29 |
2015-07-08 |
柯尼卡美能达株式会社 |
相位差膜、圆偏振片和图像显示装置
|
MX368353B
(es)
|
2012-11-02 |
2019-09-30 |
Vertex Pharma |
Composiciones farmaceuticas para el tratamiento de enfermedades mediadas por cftr.
|
WO2014078479A2
(en)
|
2012-11-14 |
2014-05-22 |
The Board Of Regents Of The University Of Texas System |
INHIBITION OF HIF-2α HETERODIMERIZATION WITH HIF1β (ARNT)
|
JP6146990B2
(ja)
|
2012-11-16 |
2017-06-14 |
コンサート ファーマシューティカルズ インコーポレイテッド |
重水素化されたcftr増強物質
|
LT2922845T
(lt)
|
2012-11-20 |
2018-09-10 |
Merial, Inc. |
Antihelmintiniai junginiai ir kompozicijos ir jų naudojimo būdai
|
ITMI20122065A1
(it)
|
2012-12-03 |
2014-06-04 |
Univ Padova |
Uso dei correttori del cftr nel trattamento delle patologie del muscolo striato
|
US20150346185A1
(en)
|
2012-12-05 |
2015-12-03 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Diagnosis of cystic fibrosis
|
CA2894279A1
(en)
|
2012-12-07 |
2014-06-12 |
Paul Boucher |
Nasal cannula for delivery of aerosolized medicaments
|
US20140221424A1
(en)
|
2013-01-30 |
2014-08-07 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions for use in the treatment of cystic fibrosis
|
US9452139B2
(en)
|
2013-03-14 |
2016-09-27 |
Novartis Ag |
Respirable agglomerates of porous carrier particles and micronized drug
|
US20140296164A1
(en)
|
2013-03-29 |
2014-10-02 |
Calista Therapeutics, Inc. |
Compositions and methods of use for cell targeted inhibitors of the Cystic Fibrosis transmembrane regulator associated ligand
|
MX368263B
(es)
|
2013-05-07 |
2019-09-26 |
Galapagos Nv |
Compuestos novedosos y composiciones farmaceuticas de los mismos para el tratamiento de fibrosis quistica.
|
WO2014190199A1
(en)
|
2013-05-24 |
2014-11-27 |
The California Institute For Biomedical Research |
Compounds for treatment of drug resistant and persistent tuberculosis
|
JP2014232188A
(ja)
|
2013-05-29 |
2014-12-11 |
コニカミノルタ株式会社 |
セルロースアシレートフィルム、円偏光板及び画像表示装置
|
CA2915975A1
(en)
|
2013-06-26 |
2014-12-31 |
Proteostasis Therapeutics, Inc. |
Methods of modulating cftr activity
|
CA2919776A1
(en)
|
2013-08-08 |
2015-02-12 |
Galapagos Nv |
Thieno[2,3-c]pyrans as cftr modulators
|
ES2716092T3
(es)
|
2013-09-12 |
2019-06-10 |
Inst Nat Sante Rech Med |
Métodos y composiciones farmacéuticas para el tratamiento de fibrosis quística
|
JP6564380B2
(ja)
|
2013-09-20 |
2019-08-21 |
ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション |
前立腺癌を治療するための化合物
|
US9353078B2
(en)
|
2013-10-01 |
2016-05-31 |
New York University |
Amino, amido and heterocyclic compounds as modulators of rage activity and uses thereof
|
WO2015054337A1
(en)
|
2013-10-09 |
2015-04-16 |
Emory University |
Heterocyclic coupling catalysts and methods related thereto
|
CA2930199C
(en)
|
2013-11-12 |
2022-10-25 |
Vertex Pharmaceuticals Incorporated |
Process of preparing pharmaceutical compositions for the treatment of cftr mediated diseases
|
KR20150062652A
(ko)
|
2013-11-29 |
2015-06-08 |
삼성전자주식회사 |
초음파 감응성 리포좀, 그를 포함한 약제학적 조성물 및 그를 이용하여 개체의 체내에 활성제를 전달하는 방법
|
CN106061480B
(zh)
|
2013-12-30 |
2020-02-28 |
莱福斯希医药公司 |
治疗性抑制性化合物
|
CA2941716A1
(en)
|
2014-03-07 |
2015-09-11 |
The Johns Hopkins University |
Inhibitors of histone lysine specific demethylase (lsd1) and histone deacetylases (hdacs)
|
JP2015172005A
(ja)
|
2014-03-11 |
2015-10-01 |
国立大学法人 東京大学 |
鉄触媒によるカップリング化合物の製造方法
|
CA2942387A1
(en)
|
2014-03-13 |
2015-09-17 |
Proteostasis Therapeutics, Inc. |
Compounds, compositions and methods of increasing cftr actvity
|
US9790219B2
(en)
|
2014-03-13 |
2017-10-17 |
Proteostasis Therapeutics, Inc. |
Compounds, compositions, and methods for increasing CFTR activity
|
PL3925607T3
(pl)
|
2014-04-15 |
2023-10-30 |
Vertex Pharmaceuticals Incorporated |
Kompozycje farmaceutyczne do leczenia chorób, w których pośredniczy mukowiscydozowy przezbłonowy regulator przewodnictwa
|
EP3139949B1
(en)
|
2014-05-08 |
2020-07-29 |
Phasebio Pharmaceuticals, Inc. |
Compositions comprising a vip-elp fusion protein for use in treating cystic fibrosis
|
US10864213B2
(en)
|
2014-05-12 |
2020-12-15 |
Verona Pharma Plc |
Treatment
|
EP3142637B1
(en)
|
2014-05-16 |
2020-07-29 |
Olaplex, Inc. |
Keratin treatment formulations and methods
|
WO2015179414A1
(en)
|
2014-05-19 |
2015-11-26 |
Merial, Inc. |
Anthelmintic compounds
|
JP6692759B2
(ja)
|
2014-06-05 |
2020-05-13 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
新規キノリン誘導体及び神経変性疾患におけるそれらの使用
|
WO2015196071A1
(en)
|
2014-06-19 |
2015-12-23 |
Proteostasis Therapeutics, Inc. |
Compounds, compositions and methods of increasing cftr activity
|
ES2966909T3
(es)
|
2014-08-13 |
2024-04-25 |
Akeso Biomedical Inc |
Compuestos y composiciones antimicrobianos, y usos de los mismos
|
GB201415381D0
(en)
|
2014-08-29 |
2014-10-15 |
Algipharma As |
Inhalable powder formulations of alginate oligomers
|
JP2017538659A
(ja)
|
2014-09-10 |
2017-12-28 |
エピザイム インコーポレイテッド |
Smyd阻害剤
|
WO2016050209A1
(zh)
|
2014-10-01 |
2016-04-07 |
厦门赛诺邦格生物科技有限公司 |
一种异官能化聚乙二醇衍生物、制备方法及其生物相关物质
|
WO2016050208A1
(zh)
|
2014-10-01 |
2016-04-07 |
厦门赛诺邦格生物科技有限公司 |
一种多官能化聚乙二醇衍生物修饰的生物相关物质
|
CN104725628B
(zh)
|
2014-10-01 |
2018-04-17 |
厦门赛诺邦格生物科技股份有限公司 |
一种含可降解基团的单一官能化支化聚乙二醇、制备方法及其生物相关物质
|
WO2016050210A1
(zh)
|
2014-10-01 |
2016-04-07 |
厦门赛诺邦格生物科技有限公司 |
一种多官能化聚乙二醇衍生物及其制备方法
|
US9855249B2
(en)
|
2014-10-02 |
2018-01-02 |
Flatley Discovery Lab, Llc |
Isoxazole compounds and methods for the treatment of cystic fibrosis
|
BR112017007072A2
(pt)
|
2014-10-06 |
2018-01-30 |
Flatley Discovery Lab Llc |
compostos de triazolopiridina e métodos para o tratamento de fibrose cística
|
NZ768373A
(en)
|
2014-10-06 |
2024-03-22 |
Vertex Pharma |
Modulators of cystic fibrosis transmembrane conductance regulator
|
WO2016057730A1
(en)
|
2014-10-07 |
2016-04-14 |
Strohmeier Mark |
Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator
|
US20160108406A1
(en)
|
2014-10-08 |
2016-04-21 |
University Of Iowa Research Foundation |
Method of regulating cftr expression and processing
|
US20170281612A1
(en)
|
2014-10-08 |
2017-10-05 |
Nivalis Therapeutics, Inc. |
Methods for the Treatment of Cystic Fibrosis
|
GB201418892D0
(en)
|
2014-10-23 |
2014-12-10 |
Proqr Therapeutics B V |
DNA editing
|
WO2016066582A1
(en)
|
2014-10-28 |
2016-05-06 |
Bci Pharma |
Nucleoside kinase inhibitors
|
CN107405337B
(zh)
|
2014-10-31 |
2021-02-09 |
艾伯维公司 |
取代的色满和使用方法
|
CN107427490A
(zh)
|
2014-10-31 |
2017-12-01 |
艾伯维公司 |
取代的四氢吡喃和使用方法
|
PT3221692T
(pt)
|
2014-11-18 |
2021-09-10 |
Vertex Pharma |
Processo de realização de testagem de alta produtividade por cromatografia líquida de alta eficiência
|
WO2016086015A1
(en)
|
2014-11-25 |
2016-06-02 |
University Of Rochester |
Myoglobin-based catalysts for carbene transfer reactions
|
WO2016086136A1
(en)
|
2014-11-26 |
2016-06-02 |
Catabasis Pharmaceuticals, Inc. |
Fatty acid cysteamine conjugates of cftr modulators and their use in treating medical disorders
|
MA41031A
(fr)
|
2014-11-26 |
2017-10-03 |
Catabasis Pharmaceuticals Inc |
Conjugués cystéamine-acide gras et leur utilisation comme activateurs de l'autophagie
|
MA41253A
(fr)
|
2014-12-23 |
2017-10-31 |
Proteostasis Therapeutics Inc |
Composés, compositions et procédés pour augmenter l'activité du cftr
|
WO2016105468A1
(en)
|
2014-12-23 |
2016-06-30 |
Proteostasis Therapeutics, Inc. |
Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis
|
CA2971850A1
(en)
|
2014-12-23 |
2016-06-30 |
Proteostasis Therapeutics, Inc. |
Derivatives of 5-phenyl- or 5-heteroarylthiazol-2-carboxylic amide useful for the treatment of inter alia cystic fibrosis
|
WO2016105484A1
(en)
|
2014-12-23 |
2016-06-30 |
Proteostasis Therapeutics, Inc. |
Derivatives of 5-(hetero)arylpyrazol-3-carboxylic amide or 1-(hetero)aryltriazol-4-carboxylic amide useful for the treatment of inter alia cystic fibrosis
|
RU2704826C2
(ru)
|
2014-12-24 |
2019-10-31 |
Китер Бьотек С.Р.Л. |
НОВЫЙ ПЕПТИД-ИНГИБИТОР PI3Kγ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ ОРГАНОВ ДЫХАНИЯ
|
WO2016109362A1
(en)
|
2014-12-31 |
2016-07-07 |
Auspex Pharmaceuticals, Inc. |
Cyclopropanecarboxamide modulators of cystic fibrosis transmembrane conductance regulator
|
WO2016107603A1
(zh)
|
2015-01-01 |
2016-07-07 |
成都贝斯凯瑞生物科技有限公司 |
取代氮杂环衍生物及其应用
|
US20180147187A1
(en)
|
2015-01-12 |
2018-05-31 |
Proteostasis Therapeutics, Inc. |
Compounds, compositions, and methods for increasing cftr activity
|
WO2016160945A1
(en)
|
2015-03-31 |
2016-10-06 |
Concert Pharmaceuticals, Inc. |
Deuterated vx-661
|
WO2018183367A1
(en)
|
2017-03-28 |
2018-10-04 |
Van Goor Fredrick F |
Methods of treating cystic fibrosis in patients with residual function mutations
|