ATE249219T1 - Antivirale verbindungen - Google Patents

Antivirale verbindungen

Info

Publication number
ATE249219T1
ATE249219T1 AT98960978T AT98960978T ATE249219T1 AT E249219 T1 ATE249219 T1 AT E249219T1 AT 98960978 T AT98960978 T AT 98960978T AT 98960978 T AT98960978 T AT 98960978T AT E249219 T1 ATE249219 T1 AT E249219T1
Authority
AT
Austria
Prior art keywords
antiviral compounds
compounds
prophylaxis
mammals
therapy
Prior art date
Application number
AT98960978T
Other languages
English (en)
Inventor
Jean Bedard
Robert Rando
Jean-Francois Lavallee
Guy Falardeau
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Application granted granted Critical
Publication of ATE249219T1 publication Critical patent/ATE249219T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT98960978T 1997-12-11 1998-12-11 Antivirale verbindungen ATE249219T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6933197P 1997-12-11 1997-12-11
PCT/CA1998/001166 WO1999029318A1 (en) 1997-12-11 1998-12-11 Antiviral compounds

Publications (1)

Publication Number Publication Date
ATE249219T1 true ATE249219T1 (de) 2003-09-15

Family

ID=22088259

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98960978T ATE249219T1 (de) 1997-12-11 1998-12-11 Antivirale verbindungen

Country Status (10)

Country Link
US (2) US6255318B1 (de)
EP (1) EP1037633B1 (de)
JP (1) JP2001525365A (de)
CN (1) CN1283995A (de)
AT (1) ATE249219T1 (de)
AU (1) AU740745B2 (de)
BR (1) BR9815166A (de)
CA (1) CA2314408A1 (de)
DE (1) DE69818094T2 (de)
WO (1) WO1999029318A1 (de)

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US6545152B1 (en) 2000-07-18 2003-04-08 Parker Hughes Institute R-isomers of nonnucleoside inhibitors
WO2002051413A2 (en) * 2000-12-27 2002-07-04 Shire Biochem Inc. Macrocyclic anti-viral compounds
ATE320255T1 (de) 2001-01-19 2006-04-15 Smithkline Beecham Corp Tie2 rezeptor-kinase-inhibitoren zur behandlung von angiogenen erkrankungen
WO2003077857A2 (en) * 2002-03-15 2003-09-25 Merck & Co., Inc. N-(substituted benzyl)-8-hydroxy-1,6-naphthyridine-7- carboxamides useful as hiv integrase inhibitors
KR100457857B1 (ko) * 2002-05-23 2004-11-18 (주) 비엔씨바이오팜 2-[2-(3-인돌릴)에틸아미노]피리딘 유도체, 그 제조방법및 이를 포함하는 항바이러스용 약학적 조성물
DE10235967B4 (de) * 2002-08-06 2005-09-08 Bayer Healthcare Ag Methode zum Identifizieren von Substanzen mit antimikrobieller Wirkung
EP1388535A1 (de) * 2002-08-07 2004-02-11 Aventis Pharma Deutschland GmbH Acylierte Arylcycloalkylamine und ihre Anwendung als Arzneimittelwirkstoff
US7329664B2 (en) * 2003-07-16 2008-02-12 Neurogen Corporation Substituted (7-pyridyl-4-phenylamino-quinazolin-2-yl)-methanol analogues
WO2005033079A1 (ja) * 2003-09-30 2005-04-14 Eisai Co., Ltd. ヘテロ環化合物を含有する新規な抗真菌剤
CN1560035A (zh) * 2004-03-12 2005-01-05 沈阳药科大学 5－羟基吲哚－3－羧酸脂类衍生物
MX2007001267A (es) * 2004-08-03 2007-07-11 Serenex Inc Derivados de naftiridinas 2,8-disustituidas.
US20080207677A1 (en) * 2004-12-31 2008-08-28 Gpc Biotech Ag Napthyridine Compounds As Rock Inhibitors
WO2007019098A2 (en) * 2005-08-04 2007-02-15 Smithkline Beecham Corporation Hiv integrase inhibitors
TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
US8183264B2 (en) * 2006-09-21 2012-05-22 Eisai R&D Managment Co., Ltd. Pyridine derivative substituted by heteroaryl ring, and antifungal agent comprising the same
US8563573B2 (en) 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
CN102702185A (zh) 2007-04-27 2012-10-03 卫材R&D管理有限公司 杂环取代吡啶衍生物的盐的结晶
TW200841879A (en) * 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
WO2008144268A1 (en) * 2007-05-15 2008-11-27 Boehringer Ingelheim International Gmbh Urotensin ii receptor antagonists
US8513287B2 (en) 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
US8236768B2 (en) * 2008-10-03 2012-08-07 3B Pharmaceuticals, Inc. Topical antiviral formulations
US8188119B2 (en) 2008-10-24 2012-05-29 Eisai R&D Management Co., Ltd Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
WO2010101949A1 (en) * 2009-03-02 2010-09-10 Sirtris Pharmaceuticals, Inc. 8-substituted quinolines and related analogs as sirtuin modulators
JP2012176900A (ja) * 2009-06-24 2012-09-13 Eisai R & D Management Co Ltd （（ホスホノオキシ）メチル）ピリジニウム環を有するピリジン誘導体およびそれらを含有する抗真菌剤
US8802868B2 (en) 2010-03-25 2014-08-12 Vertex Pharmaceuticals Incorporated Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
MX2012012204A (es) 2010-04-22 2012-12-05 Vertex Pharma Proceso para producir compuestos de cicloalquilcarboxamido-indol.
AU2012209373A1 (en) 2011-01-24 2013-04-11 Glaxosmithkline Llc Isoquinoline compounds and methods for treating HIV
CN104812387A (zh) * 2012-11-20 2015-07-29 霍夫曼-拉罗奇有限公司 取代的1,6-萘啶
DE102013107000A1 (de) 2013-07-03 2015-01-08 Kiekert Ag Kraftfahrzeugtürverschluss
ES2957761T3 (es) 2014-04-15 2024-01-25 Vertex Pharma Composiciones farmacéuticas para el tratamiento de enfermedades mediadas por el regulador de la conductancia transmembrana de fibrosis quística
US10567850B2 (en) 2016-08-26 2020-02-18 International Business Machines Corporation Hierarchical video concept tagging and indexing system for learning content orchestration
AU2019373679A1 (en) * 2018-11-02 2021-05-27 Aicuris Gmbh & Co. Kg Novel urea 6,7-dihydro-4H-thiazolo(5,4-c)pyridines active against the hepatitis B virus (HBV)
CA3141905A1 (en) * 2019-06-07 2020-12-10 Elanco Tiergesundheit Ag Bicyclic derivatives for treating endoparasites

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1620508A1 (de) * 1965-07-23 1969-09-18 Thomae Gmbh Dr K Verfahren zur Herstellung neuer 4,5,6,7-Tetrahydrothiazolo-[5,4-c]-pyridine
US4289524A (en) * 1979-10-01 1981-09-15 Velsicol Chemical Coporation Herbicidal 3-(tetrahydrobenzothiazol-2-yl)tetrahydro-1,3,5-oxadiazin-4-ones
US4500526A (en) * 1982-06-28 1985-02-19 Bristol-Myers Company Cephalosporin derivatives
US5424431A (en) * 1990-10-24 1995-06-13 Yamanouchi Pharmaceutical Co., Ltd. Thiazole derivatives
GB9605437D0 (en) * 1996-03-15 1996-05-15 Iaf Biochem Int Cytomegalovirus inhibiting compounds

Also Published As

Publication number Publication date
US20010031765A1 (en) 2001-10-18
WO1999029318A1 (en) 1999-06-17
DE69818094D1 (de) 2003-10-16
BR9815166A (pt) 2000-10-10
CN1283995A (zh) 2001-02-14
EP1037633B1 (de) 2003-09-10
EP1037633A1 (de) 2000-09-27
AU1657999A (en) 1999-06-28
JP2001525365A (ja) 2001-12-11
US6255318B1 (en) 2001-07-03
CA2314408A1 (en) 1999-06-17
AU740745B2 (en) 2001-11-15
DE69818094T2 (de) 2004-07-08
US6534520B2 (en) 2003-03-18

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Legal Events

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