ATE258930T1 - Dihydrobenzifurane - Google Patents

Dihydrobenzifurane

Info

Publication number
ATE258930T1
ATE258930T1 AT98966288T AT98966288T ATE258930T1 AT E258930 T1 ATE258930 T1 AT E258930T1 AT 98966288 T AT98966288 T AT 98966288T AT 98966288 T AT98966288 T AT 98966288T AT E258930 T1 ATE258930 T1 AT E258930T1
Authority
AT
Austria
Prior art keywords
dihydrobenzifurans
meaningand
heterocycle
meanings
compounds
Prior art date
Application number
AT98966288T
Other languages
English (en)
Inventor
Ulrich Thibaut
Armin Hatzelmann
Hildegard Boss
Dietrich Haefner
Rolf Beume
Hans-Peter Kley
Hendrik Timmerman
Der Laan Ivonne Johanna Van
Wolf-Ruediger Ulrich
Geert Jan Sterk
Der Mey Margaretha Van
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE258930T1 publication Critical patent/ATE258930T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98966288T 1997-12-15 1998-12-10 Dihydrobenzifurane ATE258930T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97122039 1997-12-15
PCT/EP1998/008054 WO1999031090A1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans

Publications (1)

Publication Number Publication Date
ATE258930T1 true ATE258930T1 (de) 2004-02-15

Family

ID=8227798

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98966288T ATE258930T1 (de) 1997-12-15 1998-12-10 Dihydrobenzifurane

Country Status (17)

Country Link
US (1) US6380196B1 (de)
EP (1) EP1042319B1 (de)
JP (1) JP2002508368A (de)
AT (1) ATE258930T1 (de)
AU (1) AU753576B2 (de)
CA (1) CA2314111A1 (de)
CZ (1) CZ299304B6 (de)
DE (1) DE69821530T2 (de)
DK (1) DK1042319T3 (de)
EE (1) EE04312B1 (de)
ES (1) ES2216349T3 (de)
HU (1) HU225114B1 (de)
IL (1) IL136359A (de)
PL (1) PL191236B1 (de)
PT (1) PT1042319E (de)
SI (1) SI1042319T1 (de)
WO (1) WO1999031090A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ302882B6 (cs) 1999-08-21 2012-01-04 Nycomed Gmbh Farmaceutický prostredek
WO2001019818A1 (en) * 1999-09-14 2001-03-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pd3/4 inhibitors
HRP20020350A2 (en) 1999-10-25 2004-02-29 Altana Pharma Ag Tetrahydrothiopy ranphtalazinone derivatives as pde4 inhibitors
US6756371B1 (en) 1999-10-25 2004-06-29 Altana Pharma Ag Phthalazinone derivatives as PDE4 inhibitors
SK17052002A3 (sk) * 2000-06-05 2003-12-02 Altana Pharma Ag Pyridazinónové zlúčeniny, farmaceutický prostriedok s ich obsahom a ich použitie
JP4301812B2 (ja) * 2001-02-15 2009-07-22 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｐｄｅ４インヒビターとしてのフタラインオン−ピペリジノ−誘導体
SK14342003A3 (sk) 2001-04-25 2004-05-04 Altana Pharma Ag Ftalazinóny, farmaceutický prostriedok s ich obsahom a ich použitie
PL363544A1 (en) * 2001-04-25 2004-11-29 Altana Pharma Ag Piperazino-derivatives and their use as pde4 inhibitor
KR20040095321A (ko) * 2002-03-29 2004-11-12 쥬가이 세이야쿠 가부시키가이샤 호흡기 질환의 예방 또는 치료용 약학 조성물
WO2004018449A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
CA2494643A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-n-oxide-derivatives
DE60313472T2 (de) * 2002-08-10 2008-01-24 Nycomed Gmbh Pyrrolidindion-substituierte piperidin-phthalazone als pde4-inhibitoren
EP1556369A1 (de) * 2002-08-10 2005-07-27 ALTANA Pharma AG Pyridazinonderivate als pde4-inhibitoren
US7153824B2 (en) 2003-04-01 2006-12-26 Applied Research Systems Ars Holding N.V. Inhibitors of phosphodiesterases in infertility
US20080227790A1 (en) * 2004-02-04 2008-09-18 Altana Pharma Ag Pyridazinone Derivatives and their Use as Pde4 Inhibitors
EP1716133B1 (de) 2004-02-04 2008-03-26 Nycomed GmbH 2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-on-derivate als pde4-inhibitoren
JP4890439B2 (ja) * 2005-03-07 2012-03-07 杏林製薬株式会社 ピラゾロピリジン−４−イルピリダジノン誘導体とその付加塩及びそれらを有効成分とするｐｄｅ阻害剤
WO2007058392A1 (ja) * 2005-11-21 2007-05-24 Japan Tobacco Inc. ヘテロ環化合物およびその医薬用途
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721784A (en) * 1986-12-22 1988-01-26 Ortho Pharmaceutical Corporation 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
CA2065364A1 (en) * 1989-04-17 1990-10-18 Hermann Amschler Arylpyridazines, their manufacture, use and medicaments containing them
AU7238191A (en) 1990-02-19 1991-09-03 Chugai Seiyaku Kabushiki Kaisha Novel fused heterocyclic compound and antiasthmatic agent prepared therefrom
AU8722991A (en) * 1990-10-16 1992-05-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Arylpyridazinones
EP0581805A1 (de) * 1991-04-26 1994-02-09 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue pyridazine
EP0593567B1 (de) * 1991-07-05 1996-08-28 Byk Gulden Lomberg Chemische Fabrik Gmbh Verwendung substituierter pyridazine gegen dermatosen
DK0612321T3 (da) 1991-10-09 1999-12-13 Syntex Inc Pyridopyridazinon- og pyridazinthionforbindelser med PDE IV inhiberende aktivitet
DE4230755A1 (de) * 1992-09-14 1994-03-17 Schering Ag Verwendung von PDE-Inhibitoren bei der Behandlung von Nieren- und Ureter-Erkrankungen
WO1994012461A1 (en) * 1992-12-02 1994-06-09 Pfizer Inc. Catechol diethers as selective pdeiv inhibitors
US5411935A (en) * 1993-03-17 1995-05-02 Sumitomo Chemical Co., Ltd. Dihydrobenzofuran derivatives, their production and use
EP0772610B9 (de) * 1994-07-22 2001-07-25 Byk Gulden Lomberg Chemische Fabrik GmbH Dihydrobenzofurane
CA2173493C (en) * 1994-08-09 2008-03-25 Nobuhisa Watanabe Fused pyridazine compounds
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
US5821250A (en) * 1996-02-01 1998-10-13 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents

Also Published As

Publication number Publication date
HU225114B1 (en) 2006-06-28
DE69821530T2 (de) 2004-12-23
HUP0004561A3 (en) 2002-04-29
US6380196B1 (en) 2002-04-30
AU2270199A (en) 1999-07-05
PL341239A1 (en) 2001-03-26
ES2216349T3 (es) 2004-10-16
CA2314111A1 (en) 1999-06-24
DE69821530D1 (de) 2004-03-11
EP1042319A1 (de) 2000-10-11
EE200000335A (et) 2001-10-15
PL191236B1 (pl) 2006-04-28
DK1042319T3 (da) 2004-06-01
EP1042319B1 (de) 2004-02-04
JP2002508368A (ja) 2002-03-19
CZ299304B6 (cs) 2008-06-11
IL136359A0 (en) 2001-06-14
HUP0004561A2 (hu) 2002-03-28
AU753576B2 (en) 2002-10-24
CZ20002218A3 (cs) 2000-11-15
IL136359A (en) 2003-03-12
SI1042319T1 (en) 2004-08-31
WO1999031090A1 (en) 1999-06-24
PT1042319E (pt) 2004-06-30
EE04312B1 (et) 2004-06-15

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