YU19499A - Benzonaftiridini kao bronhijalni terapeutici - Google Patents
Benzonaftiridini kao bronhijalni terapeuticiInfo
- Publication number
- YU19499A YU19499A YU19499A YU19499A YU19499A YU 19499 A YU19499 A YU 19499A YU 19499 A YU19499 A YU 19499A YU 19499 A YU19499 A YU 19499A YU 19499 A YU19499 A YU 19499A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- benzonaphthyridines
- bronchial therapeutics
- therapeutics
- bronchial
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
Jedinjenja formule (I) u kojoj R1, R2, R3 i R4 imaju značenja navedena u opisu, jesu novi aktivni bronhijalni terapeutici.[Compounds of formula (I) in which R1, R2, R3 and R4 have the meanings indicated in the description, are novel active bronchial therapeutics.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19646298 | 1996-11-11 | ||
EP96118188 | 1996-11-13 | ||
DE19739056 | 1997-09-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
YU19499A true YU19499A (sh) | 2001-09-28 |
RS49607B RS49607B (sr) | 2007-06-04 |
Family
ID=27216810
Country Status (31)
Country | Link |
---|---|
US (1) | US6008215A (sh) |
EP (1) | EP0937074B1 (sh) |
JP (1) | JP4223075B2 (sh) |
KR (1) | KR100484045B1 (sh) |
CN (1) | CN1090188C (sh) |
AT (1) | ATE234300T1 (sh) |
AU (1) | AU733129B2 (sh) |
BG (1) | BG63695B1 (sh) |
BR (1) | BR9713338B1 (sh) |
CA (1) | CA2270964C (sh) |
CY (1) | CY2476B1 (sh) |
CZ (1) | CZ288752B6 (sh) |
DE (1) | DE69719778T2 (sh) |
DK (1) | DK0937074T3 (sh) |
EA (1) | EA001551B1 (sh) |
EE (1) | EE03829B1 (sh) |
ES (1) | ES2195189T3 (sh) |
GE (1) | GEP20012390B (sh) |
HK (1) | HK1022151A1 (sh) |
HU (1) | HU226981B1 (sh) |
ID (1) | ID22042A (sh) |
IL (1) | IL129054A (sh) |
NO (1) | NO312764B1 (sh) |
NZ (1) | NZ334976A (sh) |
PL (1) | PL189641B1 (sh) |
PT (1) | PT937074E (sh) |
RS (1) | RS49607B (sh) |
SI (1) | SI0937074T1 (sh) |
SK (1) | SK283269B6 (sh) |
TR (1) | TR199900856T2 (sh) |
WO (1) | WO1998021208A1 (sh) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002513793A (ja) | 1998-05-05 | 2002-05-14 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | 新規n−オキシド |
SI1109810T1 (en) * | 1998-08-31 | 2004-12-31 | Altana Pharma Ag | Benzonaphthyridine-n-oxides comprising a pde3 and pde4 inhibiting activity |
IT1303272B1 (it) | 1998-10-29 | 2000-11-06 | Zambon Spa | Derivati triciclici inibitori della fosfodiesterasi 4 |
KR100720906B1 (ko) * | 1999-01-15 | 2007-05-25 | 알타나 파마 아게 | Pde-iv 억제 활성을 갖는 페닐페난트리딘 |
JP2003502278A (ja) | 1999-01-15 | 2003-01-21 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | 新規のn−オキシド |
US6534518B1 (en) | 1999-01-15 | 2003-03-18 | Altana Pharma Ag | Polysubstituted 6-phenylphenanthridines with PDE-IV inhibiting activity |
EP1147087B1 (en) | 1999-01-15 | 2005-05-11 | ALTANA Pharma AG | Phenanthridine-n-oxides with pde-iv inhibiting activity |
ATE447952T1 (de) * | 1999-08-21 | 2009-11-15 | Nycomed Gmbh | Synergistische kombination von pumafentrine und salmeterol |
NL1017973C2 (nl) * | 2000-05-10 | 2002-11-08 | Tristem Trading Cyprus Ltd | Inrichting. |
DK1377574T3 (da) * | 2001-02-21 | 2005-04-25 | Altana Pharma Ag | 6-phenylbenzonaphtyridiner |
US6479493B1 (en) | 2001-08-23 | 2002-11-12 | Cell Pathways, Inc. | Methods for treatment of type I diabetes |
CA2495603A1 (en) * | 2002-08-17 | 2004-03-04 | Altana Pharma Ag | Benzonaphthyridines with pde 3/4 inhibiting activity |
AU2003264132B2 (en) * | 2002-09-04 | 2009-11-19 | Takeda Gmbh | Novel benzonaphthyridines |
US7470704B2 (en) * | 2002-09-04 | 2008-12-30 | Nycomed Gmbh | Benzonaphthyridines |
BRPI0508321B1 (pt) | 2004-03-03 | 2018-02-06 | Takeda Gmbh | Hidróxi-6-heteroarilfenantridinas, seu uso e composições farmacêuticas que as compreende |
AR049419A1 (es) * | 2004-03-03 | 2006-08-02 | Altana Pharma Ag | Hidroxi-6-fenilfenantridinas sustituidas con heterociclilo |
WO2005087745A1 (en) * | 2004-03-10 | 2005-09-22 | Altana Pharma Ag | Novel amido-substituted hydroxy-6-phenylphenanthridines and their use as pde4 inhibitors |
WO2005090345A1 (en) * | 2004-03-17 | 2005-09-29 | Altana Pharma Ag | Novel n- (alkoxyalkyl) carbamoyl - substituted 6-phenyl-benzonaphthyridine derivatives and their use as pde3/4 inhibitors |
AU2005281703B2 (en) * | 2004-09-08 | 2011-11-17 | Takeda Gmbh | Novel 3-thia-10-aza-phenanthrene derivatives |
JP5009799B2 (ja) * | 2004-09-08 | 2012-08-22 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規の3−オキサ−10−アザ−フェナントレン |
ATE450524T1 (de) | 2005-03-02 | 2009-12-15 | Nycomed Gmbh | (2r,4ar,10br)-6-(2,6-dimethoxypyridin-3-yl)-9- ethoxy-8-methoxy-1,2,3,4,4a,10b- hexahydrophenanthridin-2-ol hydrochloridsalz |
WO2007045979A1 (en) | 2005-10-19 | 2007-04-26 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of muscarinic receptor antagonists |
TW200808695A (en) * | 2006-06-08 | 2008-02-16 | Amgen Inc | Benzamide derivatives and uses related thereto |
ES2528316T3 (es) * | 2006-09-01 | 2015-02-06 | Senhwa Biosciences, Inc. | Moduladores de la serina-treonina proteína quinasa y de PARP |
CN104016980B (zh) | 2008-04-23 | 2016-12-07 | 里格尔药品股份有限公司 | 用于治疗代谢障碍的甲酰胺化合物 |
AR079451A1 (es) | 2009-12-18 | 2012-01-25 | Nycomed Gmbh | Compuestos 3,4,4a,10b-tetrahidro-1h-tiopirano[4,3-c]isoquinolina |
CN108299429B (zh) * | 2018-04-09 | 2021-10-08 | 中南大学 | 一类八氢苯并萘啶化合物及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3899494A (en) * | 1970-05-13 | 1975-08-12 | Sandoz Ltd | Substituted 6-phenyl benzo-naphthyridines |
EP0247971A3 (en) * | 1986-05-29 | 1990-01-17 | Sandoz Ag | Novel pharmaceutical compositions comprising and use of cis-6-(4-acetanilido)-8,9-dimethoxy-2-methyl-1,2,3,4,4a,10b-hexahydrobenzo[c][1,6]naphthyridin |
MY105344A (en) * | 1990-05-16 | 1994-09-30 | Byk Gulden Lomberg Chemische Fabrik | New sulphonyl compounds |
-
1997
- 1997-11-05 EE EEP199900105A patent/EE03829B1/xx not_active IP Right Cessation
- 1997-11-05 IL IL12905497A patent/IL129054A/en not_active IP Right Cessation
- 1997-11-05 WO PCT/EP1997/006096 patent/WO1998021208A1/en active IP Right Grant
- 1997-11-05 EA EA199900421A patent/EA001551B1/ru not_active IP Right Cessation
- 1997-11-05 DK DK97950093T patent/DK0937074T3/da active
- 1997-11-05 CN CN97199529A patent/CN1090188C/zh not_active Expired - Fee Related
- 1997-11-05 ID IDW990180A patent/ID22042A/id unknown
- 1997-11-05 EP EP97950093A patent/EP0937074B1/en not_active Expired - Lifetime
- 1997-11-05 ES ES97950093T patent/ES2195189T3/es not_active Expired - Lifetime
- 1997-11-05 NZ NZ334976A patent/NZ334976A/xx not_active IP Right Cessation
- 1997-11-05 KR KR10-1999-7004024A patent/KR100484045B1/ko not_active IP Right Cessation
- 1997-11-05 JP JP52212098A patent/JP4223075B2/ja not_active Expired - Fee Related
- 1997-11-05 GE GEAP19974710A patent/GEP20012390B/en unknown
- 1997-11-05 BR BRPI9713338-8A patent/BR9713338B1/pt not_active IP Right Cessation
- 1997-11-05 DE DE69719778T patent/DE69719778T2/de not_active Expired - Lifetime
- 1997-11-05 RS YUP-194/99A patent/RS49607B/sr unknown
- 1997-11-05 PL PL97333429A patent/PL189641B1/pl unknown
- 1997-11-05 HU HU0000426A patent/HU226981B1/hu not_active IP Right Cessation
- 1997-11-05 SK SK623-99A patent/SK283269B6/sk not_active IP Right Cessation
- 1997-11-05 US US09/284,458 patent/US6008215A/en not_active Expired - Lifetime
- 1997-11-05 CZ CZ19991675A patent/CZ288752B6/cs not_active IP Right Cessation
- 1997-11-05 AT AT97950093T patent/ATE234300T1/de active
- 1997-11-05 PT PT97950093T patent/PT937074E/pt unknown
- 1997-11-05 TR TR1999/00856T patent/TR199900856T2/xx unknown
- 1997-11-05 CA CA002270964A patent/CA2270964C/en not_active Expired - Fee Related
- 1997-11-05 AU AU53170/98A patent/AU733129B2/en not_active Ceased
- 1997-11-05 SI SI9730535T patent/SI0937074T1/xx unknown
-
1999
- 1999-04-05 BG BG103310A patent/BG63695B1/bg unknown
- 1999-05-11 NO NO19992282A patent/NO312764B1/no not_active IP Right Cessation
-
2000
- 2000-02-24 HK HK00101112A patent/HK1022151A1/xx not_active IP Right Cessation
-
2004
- 2004-09-03 CY CY0400068A patent/CY2476B1/xx unknown
Also Published As
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