EE9900105A - Bensonaftüridiinid bronhiaalravimitena - Google Patents

Bensonaftüridiinid bronhiaalravimitena

Info

Publication number
EE9900105A
EE9900105A EEP199900105A EE9900105A EE9900105A EE 9900105 A EE9900105 A EE 9900105A EE P199900105 A EEP199900105 A EE P199900105A EE 9900105 A EE9900105 A EE 9900105A EE 9900105 A EE9900105 A EE 9900105A
Authority
EE
Estonia
Prior art keywords
pct
benzonaphthyridines
bronchodilators
date
sec
Prior art date
Application number
EEP199900105A
Other languages
English (en)
Other versions
EE03829B1 (et
Inventor
Gutterer Beate
Amschler Hermann
Ulrich Wolf-R�diger
Martin Thomas
B�r Thomas
Hatzelmann Armin
Sanders Karl
Beume Rolf
Boss Hildegard
H�fner Dietrich
Kley Hans-Peter
Goebel Karl-Josef
Original Assignee
Byk Gulden Lomberg Chemische Fabrik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik Gmbh filed Critical Byk Gulden Lomberg Chemische Fabrik Gmbh
Publication of EE9900105A publication Critical patent/EE9900105A/et
Publication of EE03829B1 publication Critical patent/EE03829B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
EEP199900105A 1996-11-11 1997-11-05 Bensonaftüridiinid, nende kasutamine bronhiaalravimi valmistamiseks ning neid sisaldav ravim EE03829B1 (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19646298 1996-11-11
EP96118188 1996-11-13
DE19739056 1997-09-05
PCT/EP1997/006096 WO1998021208A1 (en) 1996-11-11 1997-11-05 Benzonaphthyridines as bronchial therapeutics

Publications (2)

Publication Number Publication Date
EE9900105A true EE9900105A (et) 1999-10-15
EE03829B1 EE03829B1 (et) 2002-08-15

Family

ID=27216810

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900105A EE03829B1 (et) 1996-11-11 1997-11-05 Bensonaftüridiinid, nende kasutamine bronhiaalravimi valmistamiseks ning neid sisaldav ravim

Country Status (31)

Country Link
US (1) US6008215A (et)
EP (1) EP0937074B1 (et)
JP (1) JP4223075B2 (et)
KR (1) KR100484045B1 (et)
CN (1) CN1090188C (et)
AT (1) ATE234300T1 (et)
AU (1) AU733129B2 (et)
BG (1) BG63695B1 (et)
BR (1) BR9713338B1 (et)
CA (1) CA2270964C (et)
CY (1) CY2476B1 (et)
CZ (1) CZ288752B6 (et)
DE (1) DE69719778T2 (et)
DK (1) DK0937074T3 (et)
EA (1) EA001551B1 (et)
EE (1) EE03829B1 (et)
ES (1) ES2195189T3 (et)
GE (1) GEP20012390B (et)
HK (1) HK1022151A1 (et)
HU (1) HU226981B1 (et)
ID (1) ID22042A (et)
IL (1) IL129054A (et)
NO (1) NO312764B1 (et)
NZ (1) NZ334976A (et)
PL (1) PL189641B1 (et)
PT (1) PT937074E (et)
RS (1) RS49607B (et)
SI (1) SI0937074T1 (et)
SK (1) SK283269B6 (et)
TR (1) TR199900856T2 (et)
WO (1) WO1998021208A1 (et)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1075477T1 (en) 1998-05-05 2003-08-31 Altana Pharma Ag Novel Benzonaphthyridine-N-oxides
ATE269331T1 (de) 1998-08-31 2004-07-15 Altana Pharma Ag Benzonaphthyridin-n-oxide mit pde3 und pde4 inhibierender aktivität
IT1303272B1 (it) * 1998-10-29 2000-11-06 Zambon Spa Derivati triciclici inibitori della fosfodiesterasi 4
AU2107700A (en) * 1999-01-15 2000-08-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Phenanthridine-n-oxides with pde-iv inhibiting activity
DK1147103T3 (da) 1999-01-15 2005-08-29 Altana Pharma Ag Phenanthridin-N-oxider med PDE-IV-inhiberende aktivitet
AU2904300A (en) * 1999-01-15 2000-08-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Polysubstituted 6-phenylphenanthridines with pde-iv inhibiting activity
US6476025B1 (en) * 1999-01-15 2002-11-05 Altana Pharma Ag Phenylphennanthridines with PDE-IV inhibiting activity
TR200909479T2 (tr) 1999-08-21 2012-02-21 Nycomed Gmbh Sinerjistik kombinasyon.
NL1017973C2 (nl) * 2000-05-10 2002-11-08 Tristem Trading Cyprus Ltd Inrichting.
EP1377574B1 (en) 2001-02-21 2005-01-19 Byk Gulden Lomberg Chemische Fabrik GmbH 6-phenylbenzonaphthyridines
US6479493B1 (en) 2001-08-23 2002-11-12 Cell Pathways, Inc. Methods for treatment of type I diabetes
EP1581533A2 (en) * 2002-08-17 2005-10-05 ALTANA Pharma AG Novel benzonaphthyridines
US7470704B2 (en) 2002-09-04 2008-12-30 Nycomed Gmbh Benzonaphthyridines
CA2496731C (en) * 2002-09-04 2011-08-16 Altana Pharma Ag Novel benzonaphthyridines
AR049419A1 (es) * 2004-03-03 2006-08-02 Altana Pharma Ag Hidroxi-6-fenilfenantridinas sustituidas con heterociclilo
ES2427256T3 (es) 2004-03-03 2013-10-30 Takeda Gmbh Nuevas hidroxi-6-heteroaril-fenantridinas y su uso como agentes inhibidores de la PDE4
BRPI0508481A (pt) * 2004-03-10 2007-07-31 Altana Pharma Ag hidróxi-6-fenilenantridinas amido-substituìdas e seu uso como inibidores de pde4
CA2559200A1 (en) * 2004-03-17 2005-09-29 Altana Pharma Ag Novel n- (alkoxyalkyl) carbamoyl - substituted 6-phenyl-benzonaphthyridine derivatives and their use as pde3/4 inhibitors
EP1791847A2 (en) * 2004-09-08 2007-06-06 Altana Pharma AG Novel 3-thia-10-aza-phenanthrene derivatives
JP5009799B2 (ja) * 2004-09-08 2012-08-22 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規の３−オキサ−１０−アザ−フェナントレン
ES2337083T3 (es) 2005-03-02 2010-04-20 Nycomed Gmbh (2r,4ar,10br)-6-(2,6-dimetoxipiridin-3-il)-9-exoti-8-metoxi-1,2,3,4,4a,10b-hexahidrofenantridin-2-ol, sal de hc1.
EP1948164A1 (en) 2005-10-19 2008-07-30 Ranbaxy Laboratories, Ltd. Pharmaceutical compositions of muscarinic receptor antagonists
TW200808695A (en) * 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
CA2661842C (en) * 2006-09-01 2017-08-22 Cylene Pharmaceuticals, Inc. Tricyclic heteroaryl compounds and their use as serine-threonine protein kinases and parp modulators
NZ588652A (en) 2008-04-23 2012-09-28 Rigel Pharmaceuticals Inc Carboxamide compounds for the treatment of metabolic disorders
AR079451A1 (es) 2009-12-18 2012-01-25 Nycomed Gmbh Compuestos 3,4,4a,10b-tetrahidro-1h-tiopirano[4,3-c]isoquinolina
CN108299429B (zh) * 2018-04-09 2021-10-08 中南大学 一类八氢苯并萘啶化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
EP0247971A3 (en) * 1986-05-29 1990-01-17 Sandoz Ag Novel pharmaceutical compositions comprising and use of cis-6-(4-acetanilido)-8,9-dimethoxy-2-methyl-1,2,3,4,4a,10b-hexahydrobenzo[c][1,6]naphthyridin
MY105344A (en) * 1990-05-16 1994-09-30 Byk Gulden Lomberg Chemische Fabrik New sulphonyl compounds

Also Published As

Publication number Publication date
NZ334976A (en) 2000-10-27
SK283269B6 (sk) 2003-04-01
BG103310A (en) 2000-05-31
HU226981B1 (hu) 2010-04-28
KR100484045B1 (ko) 2005-04-20
ES2195189T3 (es) 2003-12-01
CZ167599A3 (cs) 1999-11-17
AU733129B2 (en) 2001-05-10
PT937074E (pt) 2003-07-31
NO992282D0 (no) 1999-05-11
CN1236367A (zh) 1999-11-24
CA2270964C (en) 2007-07-31
PL333429A1 (en) 1999-12-06
EP0937074B1 (en) 2003-03-12
RS49607B (sr) 2007-06-04
HUP0000426A3 (en) 2001-04-28
ATE234300T1 (de) 2003-03-15
BR9713338A (pt) 2000-05-09
EE03829B1 (et) 2002-08-15
CY2476B1 (en) 2005-05-03
CZ288752B6 (cs) 2001-08-15
WO1998021208A1 (en) 1998-05-22
YU19499A (sh) 2001-09-28
DE69719778T2 (de) 2004-02-05
DE69719778D1 (de) 2003-04-17
SI0937074T1 (en) 2003-08-31
HK1022151A1 (en) 2000-07-28
EA001551B1 (ru) 2001-04-23
BR9713338B1 (pt) 2009-12-01
NO312764B1 (no) 2002-07-01
ID22042A (id) 1999-08-26
CN1090188C (zh) 2002-09-04
IL129054A0 (en) 2000-02-17
IL129054A (en) 2002-07-25
CA2270964A1 (en) 1998-05-22
EP0937074A1 (en) 1999-08-25
SK62399A3 (en) 1999-10-08
NO992282L (no) 1999-05-11
EA199900421A1 (ru) 1999-10-28
DK0937074T3 (da) 2003-06-23
AU5317098A (en) 1998-06-03
GEP20012390B (en) 2001-03-25
TR199900856T2 (xx) 1999-07-21
BG63695B1 (bg) 2002-09-30
PL189641B1 (pl) 2005-09-30
US6008215A (en) 1999-12-28
JP4223075B2 (ja) 2009-02-12
HUP0000426A2 (hu) 2001-02-28
KR20000053100A (ko) 2000-08-25
JP2001503442A (ja) 2001-03-13

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