US6403597B1
(en)
|
1997-10-28 |
2002-06-11 |
Vivus, Inc. |
Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation
|
US6548490B1
(en)
*
|
1997-10-28 |
2003-04-15 |
Vivus, Inc. |
Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
|
AU7654200A
(en)
*
|
1999-09-14 |
2001-04-17 |
Byk Gulden Lomberg Chemische Fabrik Gmbh |
Phthalazinone derivatives as pd3/4 inhibitors
|
CZ20021457A3
(cs)
|
1999-10-25 |
2002-07-17 |
Byk Gulden Lomberg Chemische Fabrik Gmbh |
Tetrahydrothiopyranové sloučeniny
|
ATE374189T1
(de)
|
1999-10-25 |
2007-10-15 |
Nycomed Gmbh |
Phthalazinon-derivate als pde 4 hemmer
|
CO5310534A1
(es)
|
2000-08-05 |
2003-08-29 |
Glaxo Group Ltd |
Nuevos derivados de androstano anti-inflamatorios
|
GB0103630D0
(en)
|
2001-02-14 |
2001-03-28 |
Glaxo Group Ltd |
Chemical compounds
|
SK11382003A3
(sk)
|
2001-02-15 |
2004-01-08 |
Altana Pharma Ag |
Piperidino-deriváty, farmaceutický prostriedok s ich obsahom a ich použitie
|
EP1370521B1
(en)
|
2001-03-22 |
2007-12-19 |
Glaxo Group Limited |
Formanilide derivatives as beta2-adrenoreceptor agonists
|
EA200301101A1
(ru)
*
|
2001-04-25 |
2004-04-29 |
Алтана Фарма Аг |
Производные пиперазина и их применение в качестве ингибиторов pde4
|
PL363312A1
(en)
|
2001-04-25 |
2004-11-15 |
Altana Pharma Ag |
Novel phthalazinones
|
CZ20032958A3
(en)
|
2001-04-30 |
2004-03-17 |
Glaxo Group Limited |
Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
|
WO2003008396A1
(fr)
*
|
2001-07-16 |
2003-01-30 |
Nikken Chemicals Co., Ltd. |
Derive d'oxazine actif sur le plan optique
|
US6479493B1
(en)
|
2001-08-23 |
2002-11-12 |
Cell Pathways, Inc. |
Methods for treatment of type I diabetes
|
US20030073711A1
(en)
*
|
2001-08-23 |
2003-04-17 |
Whitehead Clark M. |
Methods for treatment of scleroderma
|
MXPA04002405A
(es)
|
2001-09-14 |
2004-05-31 |
Glaxo Group Limetd |
Derivados de fenetanolamina para tratamiento de enfermedades respiratorias.
|
GB0201677D0
(en)
|
2002-01-25 |
2002-03-13 |
Glaxo Group Ltd |
Medicament dispenser
|
DE60318193T2
(de)
|
2002-04-25 |
2008-12-04 |
Glaxo Group Ltd., Greenford |
Phenethanolaminderivate
|
GB0217225D0
(en)
|
2002-07-25 |
2002-09-04 |
Glaxo Group Ltd |
Medicinal compounds
|
ATE360627T1
(de)
*
|
2002-08-10 |
2007-05-15 |
Altana Pharma Ag |
Pyrrolidindion-substituierte piperidin- phthalazone als pde4-inhibitoren
|
AU2003251693A1
(en)
*
|
2002-08-10 |
2004-03-11 |
Altana Pharma Ag |
Pyridazinone-derivatives as pde4 inhibitors
|
AU2003255376A1
(en)
*
|
2002-08-10 |
2004-03-11 |
Altana Pharma Ag |
Piperidine-derivatives as pde4 inhibitors
|
AU2003260371A1
(en)
*
|
2002-08-10 |
2004-03-11 |
Altana Pharma Ag |
Piperidine-n-oxide-derivatives
|
ES2302956T3
(es)
|
2002-10-28 |
2008-08-01 |
Glaxo Group Limited |
Derivado de fenetanolamina para el tratamiento de enfermedades respiratorias.
|
PE20040950A1
(es)
|
2003-02-14 |
2005-01-01 |
Theravance Inc |
DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
|
GB0303396D0
(en)
|
2003-02-14 |
2003-03-19 |
Glaxo Group Ltd |
Medicinal compounds
|
GB0316290D0
(en)
|
2003-07-11 |
2003-08-13 |
Glaxo Group Ltd |
Novel compounds
|
GB0317374D0
(en)
|
2003-07-24 |
2003-08-27 |
Glaxo Group Ltd |
Medicament dispenser
|
GB0329182D0
(en)
|
2003-12-17 |
2004-01-21 |
Glaxo Group Ltd |
Chemical compounds
|
WO2005075437A1
(en)
*
|
2004-02-04 |
2005-08-18 |
Altana Pharma Ag |
Pyridazinone derivatives and their use as pde4 inhibitors
|
JP4778449B2
(ja)
*
|
2004-02-04 |
2011-09-21 |
ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Pde4インヒビターとしての2−(ピペリジン−4−イル)−4,5−ジヒドロ−2h−ピリダジン−3−オン誘導体
|
TWI341836B
(en)
|
2004-03-11 |
2011-05-11 |
Theravance Inc |
Biphenyl compounds useful as muscarinic receptor antagonists
|
PE20060272A1
(es)
|
2004-05-24 |
2006-05-22 |
Glaxo Group Ltd |
(2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
|
TWI307630B
(en)
|
2004-07-01 |
2009-03-21 |
Glaxo Group Ltd |
Immunoglobulins
|
GB0418045D0
(en)
|
2004-08-12 |
2004-09-15 |
Glaxo Group Ltd |
Compounds
|
JP2008510015A
(ja)
|
2004-08-16 |
2008-04-03 |
セラヴァンス, インコーポレーテッド |
β2アドレナリン作用性レセプターアゴニスト活性およびムスカリン性レセプターアンタゴニスト活性を有する化合物
|
US7579335B2
(en)
|
2005-01-10 |
2009-08-25 |
Glaxo Group Limited |
Androstane 17α-carbonate derivatives for use in the treatment of allergic and inflammatory conditions
|
PE20100737A1
(es)
|
2005-03-25 |
2010-11-27 |
Glaxo Group Ltd |
Nuevos compuestos
|
GB0514809D0
(en)
|
2005-07-19 |
2005-08-24 |
Glaxo Group Ltd |
Compounds
|
PE20071068A1
(es)
|
2005-12-20 |
2007-12-13 |
Glaxo Group Ltd |
Acido 3-(4-{[4-(4-{[3-(3,3-dimetil-1-piperidinil)propil]oxi}fenil)-1-piperidinil]carbonil}-1-naftalenil)propanoico o propenoico, sales de los mismos, como antagonistas de los receptores h1 y h3
|
AU2007242851A1
(en)
|
2006-04-20 |
2007-11-01 |
Glaxo Group Limited |
Novel compounds
|
GB0611587D0
(en)
|
2006-06-12 |
2006-07-19 |
Glaxo Group Ltd |
Novel compounds
|
WO2008013838A2
(en)
|
2006-07-25 |
2008-01-31 |
Cephalon, Inc. |
Pyridizinone derivatives
|
WO2008111631A1
(ja)
*
|
2007-03-14 |
2008-09-18 |
Nippon Shinyaku Co., Ltd. |
α-メチルベンジルアミン塩の製法
|
PE20081889A1
(es)
|
2007-03-23 |
2009-03-05 |
Smithkline Beecham Corp |
Indol carboxamidas como inhibidores de ikk2
|
US7943658B2
(en)
|
2007-07-23 |
2011-05-17 |
Bristol-Myers Squibb Company |
Indole indane amide compounds useful as CB2 agonists and method
|
WO2010068311A1
(en)
|
2008-05-23 |
2010-06-17 |
Amira Pharmaceuticals, Inc. |
5-lipoxygenase-activating protein inhibitor
|
ES2566339T3
(es)
|
2008-06-05 |
2016-04-12 |
Glaxo Group Limited |
Derivados de 4-carboxamida indazol útiles como inhibidores de PI3-quinasas
|
EP2297142B1
(en)
|
2008-06-24 |
2015-10-14 |
F. Hoffmann-La Roche AG |
Novel substituted pyridin-2-ones and pyridazin-3-ones
|
RU2507202C2
(ru)
*
|
2008-07-02 |
2014-02-20 |
Ф.Хоффманн-Ля Рош Аг |
Новые фенилпиразиноны в качестве ингибиторов киназы
|
WO2010094643A1
(en)
|
2009-02-17 |
2010-08-26 |
Glaxo Group Limited |
Quinoline derivatives and their uses for rhinitis and urticaria
|
US8524751B2
(en)
|
2009-03-09 |
2013-09-03 |
GlaxoSmithKline Intellecutual Property Development |
4-oxadiazol-2-YL-indazoles as inhibitors of P13 kinases
|
WO2010102968A1
(en)
|
2009-03-10 |
2010-09-16 |
Glaxo Group Limited |
Indole derivatives as ikk2 inhibitors
|
WO2010106016A1
(en)
|
2009-03-17 |
2010-09-23 |
Glaxo Group Limited |
Pyrimidine derivatives used as itk inhibitors
|
SG174452A1
(en)
|
2009-03-19 |
2011-10-28 |
Merck Sharp & Dohme |
RNA INTERFERENCE MEDIATED INHIBITION OF BTB AND CNC HOMOLOGY 1, BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR 1 (BACH 1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) SEQUENCE LISTING
|
JP2012520686A
(ja)
|
2009-03-19 |
2012-09-10 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いたシグナル伝達性転写因子6(STAT6)遺伝子発現のRNA干渉媒介性阻害
|
JP2012520685A
(ja)
|
2009-03-19 |
2012-09-10 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いたGATA結合タンパク質3(GATA3)遺伝子発現のRNA干渉媒介性阻害
|
JP2012520683A
(ja)
|
2009-03-19 |
2012-09-10 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いた結合組織増殖因子(CTGF)遺伝子発現のRNA干渉媒介性阻害
|
US20120004281A1
(en)
|
2009-03-27 |
2012-01-05 |
Merck Sharp & Dohme Corp |
RNA Interference Mediated Inhibition of the Nerve Growth Factor Beta Chain (NGFB) Gene Expression Using Short Interfering Nucleic Acid (siNA)
|
EP2411520A2
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE THYMIC STROMAL LYMPHOPOIETIN (TSLP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
EP2411516A1
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US20120022142A1
(en)
|
2009-03-27 |
2012-01-26 |
Merck Sharp & Dohme Corp. |
RNA Interference Mediated Inhibition of Signal Transducer and Activator of Transcription 1 (STAT1) Gene Expression Using Short Interfering Nucleic Acid (siNA)
|
EP2411517A2
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE INTERCELLULAR ADHESION MOLECULE 1 (ICAM-1)GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
TW201103892A
(en)
|
2009-04-24 |
2011-02-01 |
Glaxo Group Ltd |
Compounds
|
EP2421834A1
(en)
|
2009-04-24 |
2012-02-29 |
Glaxo Group Limited |
Pyrazole and triazole carboxamides as crac channel inhibitors
|
ME02053B
(me)
|
2009-04-30 |
2015-05-20 |
Glaxo Group Ltd |
Oksazol supstituisani indazoli kao inhibitori pi3-kinaze
|
PL2987490T3
(pl)
|
2009-07-15 |
2017-12-29 |
Theravance Biopharma R&D Ip, Llc |
Postacie krystaliczne wolnej zasady związku bifenylowego
|
US20120238559A1
(en)
|
2009-12-03 |
2012-09-20 |
Glaxo Group Limited |
Novel compounds
|
JP2013512880A
(ja)
|
2009-12-03 |
2013-04-18 |
グラクソ グループ リミテッド |
Pi3−キナーゼ阻害剤としてのインダゾール誘導体
|
WO2011067365A1
(en)
|
2009-12-03 |
2011-06-09 |
Glaxo Group Limited |
Benzpyrazole derivatives as inhibitors of p13 kinases
|
EP2512438B1
(en)
|
2009-12-16 |
2017-01-25 |
3M Innovative Properties Company |
Formulations and methods for controlling mdi particle size delivery
|
WO2011110575A1
(en)
|
2010-03-11 |
2011-09-15 |
Glaxo Group Limited |
Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases
|
GB201007203D0
(en)
|
2010-04-29 |
2010-06-16 |
Glaxo Group Ltd |
Novel compounds
|
ES2548036T3
(es)
|
2010-09-08 |
2015-10-13 |
Glaxosmithkline Intellectual Property Development Limited |
Polimorfos y sales de N-[5-[4-(5-{[(2R,6S)-2,6-dimetil-4-morfolinil]metil}-1,3-oxazol-2-il)-1H-indazol-6-il]-2-(metiloxi)-3-piridinil]metanosulfonamida
|
ES2602972T3
(es)
|
2010-09-08 |
2017-02-23 |
Glaxosmithkline Intellectual Property Development Limited |
Derivados de indazol para su uso en el tratamiento de infección por virus de la gripe
|
WO2012035055A1
(en)
|
2010-09-17 |
2012-03-22 |
Glaxo Group Limited |
Novel compounds
|
US9149462B2
(en)
|
2010-10-21 |
2015-10-06 |
Glaxo Group Limited |
Pyrazole compounds acting against allergic, inflammatory and immune disorders
|
WO2012052458A1
(en)
|
2010-10-21 |
2012-04-26 |
Glaxo Group Limited |
Pyrazole compounds acting against allergic, immune and inflammatory conditions
|
GB201018124D0
(en)
|
2010-10-27 |
2010-12-08 |
Glaxo Group Ltd |
Polymorphs and salts
|
JP2014507458A
(ja)
|
2011-03-11 |
2014-03-27 |
グラクソ グループ リミテッド |
Sykインヒビターとしてのピリド[3,4−B]ピラジン誘導体
|
GB201104153D0
(en)
|
2011-03-11 |
2011-04-27 |
Glaxo Group Ltd |
Novel compounds
|
CN103582644B
(zh)
*
|
2011-06-17 |
2016-07-20 |
塔科达有限责任公司 |
酞嗪酮-吡咯并嘧啶羧酰胺衍生物
|
EP2804603A1
(en)
|
2012-01-10 |
2014-11-26 |
President and Fellows of Harvard College |
Beta-cell replication promoting compounds and methods of their use
|
CN105307655B
(zh)
|
2013-03-13 |
2019-05-03 |
弗拉特利发现实验室有限责任公司 |
哒嗪酮化合物及其用于制备治疗囊肿状纤维化的药物的应用
|
US20140275102A1
(en)
*
|
2013-03-14 |
2014-09-18 |
Cephalon, Inc. |
Solid State Forms of 6-[4-[3-((R)-2-Methylpyrrolidine-1-yl)-propoxy]phenyl] 2H-pyridazine-3-one Hydrochloride
|
AU2014336251A1
(en)
|
2013-10-17 |
2016-04-14 |
Glaxosmithkline Intellectual Property Development Limited |
PI3K inhibitor for treatment of respiratory disease
|
JP2016537327A
(ja)
|
2013-10-17 |
2016-12-01 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
呼吸器疾患の治療のためのpi3k阻害剤
|
KR20170003673A
(ko)
|
2014-05-12 |
2017-01-09 |
글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 |
감염성 질환을 치료하기 위한 다니릭신을 포함하는 약제 조성물
|
EP3180319B1
(en)
|
2014-08-14 |
2018-10-03 |
F.Hoffmann-La Roche Ag |
Novel pyridazones and triazinones for the treatment and prophylaxis of hepatitis b virus infection
|
CN104478809B
(zh)
*
|
2014-11-14 |
2016-08-17 |
成都新恒创药业有限公司 |
一种左西孟旦杂质及其制备和检测方法
|
GB201602527D0
(en)
|
2016-02-12 |
2016-03-30 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
US20190161480A1
(en)
|
2016-08-08 |
2019-05-30 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical Compounds
|
WO2018094392A1
(en)
|
2016-11-21 |
2018-05-24 |
Lupin Inc. |
Medicament dispenser
|
GB201706102D0
(en)
|
2017-04-18 |
2017-05-31 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
GB201712081D0
(en)
|
2017-07-27 |
2017-09-13 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
WO2019195711A1
(en)
|
2018-04-06 |
2019-10-10 |
Lupin Inc. |
Medicament dispenser
|
WO2020058823A1
(en)
|
2018-09-17 |
2020-03-26 |
Lupin, Inc. |
Dose indicator assembly for a medicament dispenser
|
CN115916305A
(zh)
|
2020-03-25 |
2023-04-04 |
陆品公司 |
多载体药物分配器
|
WO2022020506A1
(en)
|
2020-07-23 |
2022-01-27 |
Lupin Inc. |
Dose counter assemblies for medicament dispensers
|