ATE286887T1 - Antibakterielle mittel - Google Patents

Antibakterielle mittel

Info

Publication number
ATE286887T1
ATE286887T1 AT00914262T AT00914262T ATE286887T1 AT E286887 T1 ATE286887 T1 AT E286887T1 AT 00914262 T AT00914262 T AT 00914262T AT 00914262 T AT00914262 T AT 00914262T AT E286887 T1 ATE286887 T1 AT E286887T1
Authority
AT
Austria
Prior art keywords
antibacterial agents
atoms
fused
optionally substituted
heterocyclic ring
Prior art date
Application number
AT00914262T
Other languages
English (en)
Inventor
Raymond P Beckett
Mark Whittaker
Zoe Marie Spavold
Original Assignee
Vernalis Oxford Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vernalis Oxford Ltd filed Critical Vernalis Oxford Ltd
Application granted granted Critical
Publication of ATE286887T1 publication Critical patent/ATE286887T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/02—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
    • C07D245/02—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/06—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT00914262T 1999-03-29 2000-03-28 Antibakterielle mittel ATE286887T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9907055.9A GB9907055D0 (en) 1999-03-29 1999-03-29 Antibacterial agents
PCT/GB2000/001175 WO2000058294A1 (en) 1999-03-29 2000-03-28 Antibacterial agents

Publications (1)

Publication Number Publication Date
ATE286887T1 true ATE286887T1 (de) 2005-01-15

Family

ID=10850463

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00914262T ATE286887T1 (de) 1999-03-29 2000-03-28 Antibakterielle mittel

Country Status (9)

Country Link
US (1) US6503897B1 (de)
EP (1) EP1165532B1 (de)
JP (1) JP2002540197A (de)
AT (1) ATE286887T1 (de)
AU (1) AU3565700A (de)
DE (1) DE60017374T2 (de)
ES (1) ES2235844T3 (de)
GB (1) GB9907055D0 (de)
WO (1) WO2000058294A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004018453A1 (ja) * 2002-08-23 2004-03-04 Dainippon Pharmaceutical Co., Ltd. プロリン誘導体
ES2390767T3 (es) * 2002-12-11 2012-11-16 Glaxosmithkline Llc Inhibidores de la péptido desformilasa
EP1641778A1 (de) * 2003-06-26 2006-04-05 Novartis AG Verfahren zur herstellung von zwischenprodukten für antibakterielle n-formyl hydroxylamine
KR100753796B1 (ko) * 2006-07-28 2007-08-31 주식회사 프로메디텍 데포르밀라제 저해제, 이의 제조방법, 및 이를 포함하는조성물
MX2012007508A (es) * 2009-12-28 2012-08-01 Ajinotomo Co Inc Derivados de lantionina.
CN102452998B (zh) * 2010-10-20 2014-12-10 天津药物研究院 N-甲酰羟胺类化合物及其制备方法和用途
KR101462851B1 (ko) 2012-10-24 2014-11-18 일동제약주식회사 신규 펩티드 데포르밀라제 저해제 화합물 및 그 제조방법
US9889204B2 (en) 2014-08-11 2018-02-13 The Regents Of The University Of California Polymeric antibiotics
WO2023201067A2 (en) 2022-04-14 2023-10-19 W. L. Gore & Associates, Inc. Chemical entities

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013792A (en) 1993-08-05 2000-01-11 Syntex (U.S.A.), Inc. Matrix metalloprotease inhibitors
JPH09501430A (ja) 1993-08-05 1997-02-10 シンテックス（ユー・エス・エイ）・インコーポレイテッド マトリックスメタロプロテアーゼ阻害因子
CA2251292A1 (en) * 1996-04-12 1997-10-23 Bristol-Myers Squibb Company N-formyl hydroxylamine containing compounds useful as ace inhibitors and/or nep inhibitors
EP1052984B1 (de) * 1998-02-07 2004-05-12 Vernalis (Oxford) Ltd Antibakterielle mittel
US6288063B1 (en) * 1998-05-27 2001-09-11 Bayer Corporation Substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors

Also Published As

Publication number Publication date
ES2235844T3 (es) 2005-07-16
AU3565700A (en) 2000-10-16
DE60017374T2 (de) 2005-12-01
JP2002540197A (ja) 2002-11-26
EP1165532B1 (de) 2005-01-12
US6503897B1 (en) 2003-01-07
WO2000058294A1 (en) 2000-10-05
DE60017374D1 (de) 2005-02-17
EP1165532A1 (de) 2002-01-02
GB9907055D0 (en) 1999-05-19

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Legal Events

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