HN2006000969A - Derivados de piridinilo y pirimidinilo sustituidos como moduladores del metabolismo y para tratar trastornos metabolicos - Google Patents

Derivados de piridinilo y pirimidinilo sustituidos como moduladores del metabolismo y para tratar trastornos metabolicos

Info

Publication number
HN2006000969A
HN2006000969A HN2006000969A HN2006000969A HN2006000969A HN 2006000969 A HN2006000969 A HN 2006000969A HN 2006000969 A HN2006000969 A HN 2006000969A HN 2006000969 A HN2006000969 A HN 2006000969A HN 2006000969 A HN2006000969 A HN 2006000969A
Authority
HN
Honduras
Prior art keywords
piridinyl
metabolic disorders
treat metabolic
pyrimidinyl derivatives
metabolism modulators
Prior art date
Application number
HN2006000969A
Other languages
English (en)
Inventor
M Jones Robert
Lehmann Juerg
Siu-Ting Wong Ami
Hurst David
Shin Young-Jun
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of HN2006000969A publication Critical patent/HN2006000969A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invencion esta relaciona da con ciertos derivados de piridinilo y pirimidinilo sustituidos que son moduladores del metabolismo de la glucosa.
HN2006000969A 2005-01-10 2006-01-09 Derivados de piridinilo y pirimidinilo sustituidos como moduladores del metabolismo y para tratar trastornos metabolicos HN2006000969A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64284005P 2005-01-10 2005-01-10

Publications (1)

Publication Number Publication Date
HN2006000969A true HN2006000969A (es) 2010-03-29

Family

ID=36755755

Family Applications (2)

Application Number Title Priority Date Filing Date
HN2006000969A HN2006000969A (es) 2005-01-10 2006-01-09 Derivados de piridinilo y pirimidinilo sustituidos como moduladores del metabolismo y para tratar trastornos metabolicos
HN2010000430A HN2010000430A (es) 2005-01-10 2010-03-05 Derivados de piridinilo y pirimidinilo sustituidos como modulares del metabolismo y para tratar trastornos metabolicos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
HN2010000430A HN2010000430A (es) 2005-01-10 2010-03-05 Derivados de piridinilo y pirimidinilo sustituidos como modulares del metabolismo y para tratar trastornos metabolicos.

Country Status (37)

Country Link
US (3) US20060155128A1 (es)
EP (2) EP1911756B9 (es)
JP (1) JP2008526882A (es)
KR (1) KR20070098907A (es)
CN (2) CN101115740A (es)
AR (1) AR054320A1 (es)
AT (2) ATE446293T1 (es)
AU (1) AU2006211583C1 (es)
BR (1) BRPI0606704A (es)
CA (1) CA2594466A1 (es)
CR (1) CR9225A (es)
CY (2) CY1107215T1 (es)
DE (2) DE602006009946D1 (es)
DK (2) DK1911756T3 (es)
EA (1) EA015714B1 (es)
ES (2) ES2299167T4 (es)
GE (1) GEP20094828B (es)
GT (1) GT200600006A (es)
HK (2) HK1094542A1 (es)
HN (2) HN2006000969A (es)
HR (2) HRP20080113T3 (es)
IL (1) IL184363A0 (es)
MX (1) MX2007008402A (es)
MY (1) MY148521A (es)
NI (1) NI200700169A (es)
NO (1) NO20073806L (es)
NZ (1) NZ556220A (es)
PE (2) PE20060857A1 (es)
PL (2) PL1911756T3 (es)
PT (2) PT1732562E (es)
RS (2) RS51007B (es)
SG (1) SG158875A1 (es)
SI (2) SI1732562T1 (es)
TW (1) TW200637845A (es)
UA (1) UA89812C2 (es)
WO (1) WO2006083491A2 (es)
ZA (1) ZA200705471B (es)

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DE602006000339T2 (de) 2009-01-22
US20070167473A1 (en) 2007-07-19
CR9225A (es) 2008-01-21
EP1732562A2 (en) 2006-12-20
NO20073806L (no) 2007-09-27

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