GT201100308A - Derivados de 1-(piperidin-4-il)-pirazol como moduladores de gpr 119 - Google Patents

Derivados de 1-(piperidin-4-il)-pirazol como moduladores de gpr 119

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Publication number
GT201100308A
GT201100308A GT201100308A GT201100308A GT201100308A GT 201100308 A GT201100308 A GT 201100308A GT 201100308 A GT201100308 A GT 201100308A GT 201100308 A GT201100308 A GT 201100308A GT 201100308 A GT201100308 A GT 201100308A
Authority
GT
Guatemala
Prior art keywords
pirazol
gpr
piperidin
modulators
derivatives
Prior art date
Application number
GT201100308A
Other languages
English (en)
Inventor
Mcclure Kim Francis
Munchhof Michael John
Robinson Jr Ralph Pelton
Lefker Bruce Allen
Futatsugi Kentaro
Kung Daniel Wei-Shung
Mascitti Vincent
Deninno Michael Paul
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GT201100308A publication Critical patent/GT201100308A/es

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

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  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
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  • Immunology (AREA)
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Abstract

LA PRESENTE SOLICITUD DESCRIBE COMPUESTOS DE FÓRMULA I QUE MODULAN LA ACTIVIDAD DEL RECEPTOR ACOPLADO A PROTEÍNA G GPR119 Y SUS USOS EN EL TRATAMIENTO DE ENFERMEDADES LIGADAS A LA MODULACIÓN DEL RECEPTOR ACOPLADO A PROTEÍNA G GPR119.
GT201100308A 2009-06-05 2011-12-01 Derivados de 1-(piperidin-4-il)-pirazol como moduladores de gpr 119 GT201100308A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18435509P 2009-06-05 2009-06-05
US25762109P 2009-11-03 2009-11-03

Publications (1)

Publication Number Publication Date
GT201100308A true GT201100308A (es) 2013-11-11

Family

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GT201100308A GT201100308A (es) 2009-06-05 2011-12-01 Derivados de 1-(piperidin-4-il)-pirazol como moduladores de gpr 119

Country Status (33)

Country Link
US (1) US20110020460A1 (es)
EP (1) EP2438051A1 (es)
JP (1) JP2012528847A (es)
KR (1) KR20120061063A (es)
CN (1) CN102459222B (es)
AP (1) AP2799A (es)
AR (1) AR076985A1 (es)
AU (1) AU2010255422B2 (es)
BR (1) BRPI1014636A2 (es)
CA (1) CA2764021C (es)
CL (1) CL2011003085A1 (es)
CO (1) CO6470897A2 (es)
CR (1) CR20110623A (es)
CU (1) CU20110225A7 (es)
DO (1) DOP2011000371A (es)
EA (1) EA020106B1 (es)
EC (1) ECSP11011493A (es)
GE (1) GEP20135907B (es)
GT (1) GT201100308A (es)
HN (1) HN2011003195A (es)
IL (1) IL216772A0 (es)
MA (1) MA33334B1 (es)
MX (1) MX2011013034A (es)
NI (1) NI201100204A (es)
NZ (1) NZ596467A (es)
PE (1) PE20120399A1 (es)
SG (1) SG175995A1 (es)
SV (1) SV2011004063A (es)
TN (1) TN2012000073A1 (es)
TW (1) TWI411611B (es)
UY (1) UY32683A (es)
WO (1) WO2010140092A1 (es)
ZA (1) ZA201108481B (es)

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TWI411611B (zh) 2013-10-11
IL216772A0 (en) 2012-03-01
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AU2010255422A1 (en) 2011-12-22
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EP2438051A1 (en) 2012-04-11
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