MX2013002430A - Formas de dosis de disolucion de rápida de agonistas de 5-ht2c. - Google Patents
Formas de dosis de disolucion de rápida de agonistas de 5-ht2c.Info
- Publication number
- MX2013002430A MX2013002430A MX2013002430A MX2013002430A MX2013002430A MX 2013002430 A MX2013002430 A MX 2013002430A MX 2013002430 A MX2013002430 A MX 2013002430A MX 2013002430 A MX2013002430 A MX 2013002430A MX 2013002430 A MX2013002430 A MX 2013002430A
- Authority
- MX
- Mexico
- Prior art keywords
- dosage forms
- fast
- ht2c agonists
- dissolve dosage
- ht2c
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Abstract
Se describen sales del agonista del receptor 5-HT2c (R)-8-cloro-1-metil-2, 3, 4, 5-tetrahidro-1H-3-benzazepina, y formas de dosis que las comprenden que son útiles para, entre otras cosas, el manejo del peso.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40258910P | 2010-09-01 | 2010-09-01 | |
PCT/US2011/049953 WO2012030951A1 (en) | 2010-09-01 | 2011-08-31 | Fast-dissolve dosage forms of 5-ht2c agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2013002430A true MX2013002430A (es) | 2013-07-22 |
Family
ID=44645827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013002430A MX2013002430A (es) | 2010-09-01 | 2011-08-31 | Formas de dosis de disolucion de rápida de agonistas de 5-ht2c. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20140148442A1 (es) |
EP (1) | EP2611781A1 (es) |
JP (1) | JP2013536858A (es) |
KR (1) | KR20130138768A (es) |
CN (1) | CN103189358A (es) |
AU (1) | AU2011296027A1 (es) |
CA (1) | CA2808900A1 (es) |
IN (1) | IN2013DN02552A (es) |
MX (1) | MX2013002430A (es) |
SG (2) | SG10201506873WA (es) |
WO (1) | WO2012030951A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6272695B2 (ja) | 2010-09-01 | 2018-01-31 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 体重管理のために有用な5−ht2cアゴニストの改変放出剤形 |
JP2013536859A (ja) | 2010-09-01 | 2013-09-26 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 5−ht2cアゴニストの非吸湿性塩 |
AU2011296015B2 (en) | 2010-09-01 | 2015-11-12 | Arena Pharmaceuticals, Inc. | Administration of lorcaserin to individuals with renal impairment |
SG10201506870PA (en) | 2010-09-01 | 2015-10-29 | Arena Pharm Inc | Salts of lorcaserin with optically active acids |
CA2886875A1 (en) | 2012-10-09 | 2014-04-17 | Arena Pharmaceuticals, Inc. | Method of weight management |
WO2014135545A1 (en) * | 2013-03-05 | 2014-09-12 | Sandoz Ag | Solid dispersion comprising amorphous lorcaserin hydrochloride |
CN105431415A (zh) * | 2013-05-20 | 2016-03-23 | 斯洛文尼亚莱柯制药股份有限公司 | 通过烯烃的弗瑞德-克来福特烷基化进行的8-氯-3-苯并[d]氮杂*的新合成方法 |
EP2868656A1 (en) * | 2013-11-05 | 2015-05-06 | LEK Pharmaceuticals d.d. | Stabilized amorphous lorcaserin hydrochloride |
WO2015096119A1 (zh) * | 2013-12-27 | 2015-07-02 | 杭州普晒医药科技有限公司 | 氯卡色林盐及其晶体、其制备方法和用途 |
CN105228986B (zh) | 2014-04-21 | 2017-11-07 | 杭州普晒医药科技有限公司 | 一种氯卡色林共晶及其制备方法、药物组合物和用途 |
CN103901151A (zh) * | 2014-04-23 | 2014-07-02 | 湖北朗昕生化药业有限公司 | 一种hplc法检测氯卡色林盐酸盐含量的方法 |
WO2016069875A1 (en) | 2014-10-30 | 2016-05-06 | Arena Pharmaceuticals, Inc. | Compositions and methods for ceasing tobacco smoking |
MX2018016411A (es) | 2016-06-29 | 2019-05-09 | Cannscience Innovations Inc | Resinas de cannabis descarboxiladas, usos de las mismas y metodos para elaborarlas. |
Family Cites Families (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2561916B1 (fr) | 1984-03-30 | 1987-12-11 | Lafon Labor | Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau |
US4642903A (en) | 1985-03-26 | 1987-02-17 | R. P. Scherer Corporation | Freeze-dried foam dosage form |
US5073374A (en) | 1988-11-30 | 1991-12-17 | Schering Corporation | Fast dissolving buccal tablet |
US5112616A (en) | 1988-11-30 | 1992-05-12 | Schering Corporation | Fast dissolving buccal tablet |
US5219574A (en) | 1989-09-15 | 1993-06-15 | Cima Labs. Inc. | Magnesium carbonate and oil tableting aid and flavoring additive |
US5223264A (en) | 1989-10-02 | 1993-06-29 | Cima Labs, Inc. | Pediatric effervescent dosage form |
US5178878A (en) | 1989-10-02 | 1993-01-12 | Cima Labs, Inc. | Effervescent dosage form with microparticles |
US5188825A (en) | 1989-12-28 | 1993-02-23 | Iles Martin C | Freeze-dried dosage forms and methods for preparing the same |
EP0589973A1 (en) * | 1991-06-21 | 1994-04-06 | Smithkline Beecham Plc | Medicaments |
US5464632C1 (en) | 1991-07-22 | 2001-02-20 | Prographarm Lab | Rapidly disintegratable multiparticular tablet |
ATE216577T1 (de) | 1992-01-29 | 2002-05-15 | Takeda Chemical Industries Ltd | Schnellösliche tablette und ihre herstellung |
DE4203932A1 (de) | 1992-02-11 | 1993-08-12 | Deutsche Aerospace | Sende-/empfangsmodul |
US5503846A (en) | 1993-03-17 | 1996-04-02 | Cima Labs, Inc. | Base coated acid particles and effervescent formulation incorporating same |
US5631023A (en) | 1993-07-09 | 1997-05-20 | R.P. Scherer Corporation | Method for making freeze dried drug dosage forms |
US5895664A (en) | 1993-09-10 | 1999-04-20 | Fuisz Technologies Ltd. | Process for forming quickly dispersing comestible unit and product therefrom |
US5622719A (en) | 1993-09-10 | 1997-04-22 | Fuisz Technologies Ltd. | Process and apparatus for making rapidly dissolving dosage units and product therefrom |
US5851553A (en) | 1993-09-10 | 1998-12-22 | Fuisz Technologies, Ltd. | Process and apparatus for making rapidly dissolving dosage units and product therefrom |
US5595761A (en) | 1994-01-27 | 1997-01-21 | The Board Of Regents Of The University Of Oklahoma | Particulate support matrix for making a rapidly dissolving tablet |
US5576014A (en) | 1994-01-31 | 1996-11-19 | Yamanouchi Pharmaceutical Co., Ltd | Intrabuccally dissolving compressed moldings and production process thereof |
US5635210A (en) | 1994-02-03 | 1997-06-03 | The Board Of Regents Of The University Of Oklahoma | Method of making a rapidly dissolving tablet |
US5567439A (en) | 1994-06-14 | 1996-10-22 | Fuisz Technologies Ltd. | Delivery of controlled-release systems(s) |
GB9421836D0 (en) | 1994-10-28 | 1994-12-14 | Scherer Corp R P | Process for preparing solid pharmaceutical dosage forms of hydrophobic substances |
US5639475A (en) | 1995-02-03 | 1997-06-17 | Eurand America, Incorporated | Effervescent microcapsules |
US5607697A (en) | 1995-06-07 | 1997-03-04 | Cima Labs, Incorporated | Taste masking microparticles for oral dosage forms |
US5807578A (en) | 1995-11-22 | 1998-09-15 | Lab Pharmaceutical Research International Inc. | Fast-melt tablet and method of making same |
US5807577A (en) | 1995-11-22 | 1998-09-15 | Lab Pharmaceutical Research International Inc. | Fast-melt tablet and method of making same |
AU722289B2 (en) | 1996-10-01 | 2000-07-27 | Aptalis Pharmatech, Inc. | Taste-masked microcapsule compositions and methods of manufacture |
US6024981A (en) | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
US5869098A (en) | 1997-08-20 | 1999-02-09 | Fuisz Technologies Ltd. | Fast-dissolving comestible units formed under high-speed/high-pressure conditions |
US6316029B1 (en) | 2000-05-18 | 2001-11-13 | Flak Pharma International, Ltd. | Rapidly disintegrating solid oral dosage form |
GB0111186D0 (en) * | 2001-05-08 | 2001-06-27 | Smithkline Beecham Plc | Novel compounds |
WO2003014732A1 (en) * | 2001-08-10 | 2003-02-20 | Symyx Technologies, Inc. | Apparatuses and methods for creating and testing pre-formulations and systems for same |
EP1494533A2 (en) | 2002-04-12 | 2005-01-12 | The University of Chicago | Farnesoid x-activated receptor agonists |
US6953787B2 (en) * | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
JP4920409B2 (ja) * | 2003-06-17 | 2012-04-18 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 3−ベンズアゼピンを調製する方法 |
CN1805939B (zh) * | 2003-06-17 | 2010-10-13 | 艾尼纳制药公司 | 用于治疗5ht2c受体相关病症的苯并氮杂卓衍生物 |
TW200510324A (en) * | 2003-08-11 | 2005-03-16 | Lilly Co Eli | 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist |
WO2005042491A1 (en) * | 2003-10-22 | 2005-05-12 | Arena Pharmaceuticals, Inc. | Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases |
DK1720836T3 (da) * | 2004-02-25 | 2014-05-05 | Lilly Co Eli | 6-substituerede 2,3,4,5-tetrahydro-1h-benzo [d]azepiner som 5-ht2c-receptoragonister |
NZ589756A (en) * | 2004-12-21 | 2012-05-25 | Arena Pharm Inc | Method for the preparation of crystalline forms of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride |
EP1833473B1 (en) | 2004-12-23 | 2009-09-09 | Arena Pharmaceuticals, Inc. | 5ht2c receptor modulator compositions and methods of use |
MY148521A (en) | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
DK1924560T3 (da) * | 2005-09-01 | 2009-10-19 | Lilly Co Eli | 6-substituerede-2,3,4,5-tetrahydro-1H-benzo[d]azepiner som 5-HT2C-receptoragonister |
BRPI0615033A2 (pt) * | 2005-09-01 | 2011-04-26 | Lilly Co Eli | composto, composição farmacêutica, e, uso de um composto |
CA2646044A1 (en) * | 2006-04-03 | 2007-10-25 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto |
WO2008070111A2 (en) * | 2006-12-05 | 2008-06-12 | Arena Pharmaceuticals, Inc. | Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof |
RS52065B (en) | 2007-01-04 | 2012-06-30 | Prosidion Ltd | PIPERIDINSKI GPCR AGONIST |
WO2009051747A1 (en) * | 2007-10-15 | 2009-04-23 | Concert Pharmaceuticals, Inc. | Deuterated lorcaserin |
JP5491421B2 (ja) | 2008-03-04 | 2014-05-14 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 5−ht2cアゴニストである(r)−8−クロロ−1−メチル−2,3,4,5−テトラヒドロ−1h−3−ベンゾアゼピンに関連する中間体の調製のためのプロセス |
KR20100134659A (ko) | 2008-03-31 | 2010-12-23 | 메타볼렉스, 인코포레이티드 | 옥시메틸렌 아릴 화합물 및 그것의 사용 |
BRPI0914891A2 (pt) | 2008-06-20 | 2015-11-24 | Metabolex Inc | agonistas de aril gpr119 e usos dos mesmos |
AU2009290911A1 (en) | 2008-09-10 | 2010-03-18 | Boehringer Ingelheim International Gmbh | Combination therapy for the treatment of diabetes and related conditions |
CA2766696A1 (en) | 2009-06-24 | 2010-12-29 | Boehringer Ingelheim International Gmbh | New compounds, pharmaceutical composition and methods relating thereto |
-
2011
- 2011-08-31 CN CN201180052517XA patent/CN103189358A/zh active Pending
- 2011-08-31 KR KR1020137008322A patent/KR20130138768A/ko not_active Application Discontinuation
- 2011-08-31 MX MX2013002430A patent/MX2013002430A/es not_active Application Discontinuation
- 2011-08-31 AU AU2011296027A patent/AU2011296027A1/en not_active Abandoned
- 2011-08-31 US US13/820,123 patent/US20140148442A1/en not_active Abandoned
- 2011-08-31 WO PCT/US2011/049953 patent/WO2012030951A1/en active Application Filing
- 2011-08-31 CA CA2808900A patent/CA2808900A1/en not_active Abandoned
- 2011-08-31 IN IN2552DEN2013 patent/IN2013DN02552A/en unknown
- 2011-08-31 SG SG10201506873WA patent/SG10201506873WA/en unknown
- 2011-08-31 EP EP11755511.0A patent/EP2611781A1/en not_active Withdrawn
- 2011-08-31 SG SG2013015607A patent/SG188363A1/en unknown
- 2011-08-31 JP JP2013527262A patent/JP2013536858A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
SG188363A1 (en) | 2013-04-30 |
AU2011296027A1 (en) | 2013-04-04 |
CA2808900A1 (en) | 2012-03-08 |
SG10201506873WA (en) | 2015-10-29 |
WO2012030951A1 (en) | 2012-03-08 |
CN103189358A (zh) | 2013-07-03 |
EP2611781A1 (en) | 2013-07-10 |
US20140148442A1 (en) | 2014-05-29 |
IN2013DN02552A (es) | 2015-08-07 |
KR20130138768A (ko) | 2013-12-19 |
JP2013536858A (ja) | 2013-09-26 |
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Legal Events
Date | Code | Title | Description |
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GD | Licence granted | ||
FA | Abandonment or withdrawal |