HK1023577A1 - Anti-vegf antibodies - Google Patents

Anti-vegf antibodies

Info

Publication number
HK1023577A1
HK1023577A1 HK00102696A HK00102696A HK1023577A1 HK 1023577 A1 HK1023577 A1 HK 1023577A1 HK 00102696 A HK00102696 A HK 00102696A HK 00102696 A HK00102696 A HK 00102696A HK 1023577 A1 HK1023577 A1 HK 1023577A1
Authority
HK
Hong Kong
Prior art keywords
vegf
vegf antibodies
vitro
antibodies
inhobit
Prior art date
Application number
HK00102696A
Other languages
English (en)
Inventor
Manuel Baca
James A Wells
Leonard G Presta
Henry B Lowman
Yvonne Man-Yee Chen
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27125626&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1023577(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/908,469 external-priority patent/US6884879B1/en
Application filed by Genentech Inc filed Critical Genentech Inc
Priority to HK06106660A priority Critical patent/HK1084402A1/xx
Publication of HK1023577A1 publication Critical patent/HK1023577A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/005Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
HK00102696A 1997-04-07 2000-05-04 Anti-vegf antibodies HK1023577A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HK06106660A HK1084402A1 (en) 1997-04-07 2000-05-04 Anti-vegf antibodies

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83350497A 1997-04-07 1997-04-07
US08/908,469 US6884879B1 (en) 1997-04-07 1997-08-06 Anti-VEGF antibodies
PCT/US1998/006604 WO1998045331A2 (en) 1997-04-07 1998-04-03 Anti-vegf antibodies

Publications (1)

Publication Number Publication Date
HK1023577A1 true HK1023577A1 (en) 2000-09-15

Family

ID=27125626

Family Applications (2)

Application Number Title Priority Date Filing Date
HK06106660A HK1084402A1 (en) 1997-04-07 2000-05-04 Anti-vegf antibodies
HK00102696A HK1023577A1 (en) 1997-04-07 2000-05-04 Anti-vegf antibodies

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK06106660A HK1084402A1 (en) 1997-04-07 2000-05-04 Anti-vegf antibodies

Country Status (26)

Country Link
US (2) US7060269B1 (el)
EP (4) EP1650220B1 (el)
JP (1) JP3957765B2 (el)
KR (2) KR100816621B1 (el)
CN (1) CN100480269C (el)
AT (2) ATE293640T1 (el)
AU (1) AU743758B2 (el)
BR (1) BRPI9809387B8 (el)
CA (1) CA2286330C (el)
CY (3) CY2005008I2 (el)
DE (5) DE122005000026I1 (el)
DK (2) DK1325932T5 (el)
ES (2) ES2273415T3 (el)
FR (2) FR05C0020I2 (el)
GE (1) GEP20105118B (el)
HK (2) HK1084402A1 (el)
IL (1) IL132240A0 (el)
LT (1) LTPA2005005I1 (el)
LU (2) LU91167I2 (el)
NL (2) NL300193I2 (el)
NO (3) NO324264B1 (el)
NZ (1) NZ500078A (el)
PT (1) PT1325932E (el)
SI (1) SI1325932T1 (el)
TR (1) TR199903123T2 (el)
WO (1) WO1998045331A2 (el)

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