ECSP066461A - Método para activar las poblaciones de célula especificas utilizando conjugados maitansinoides del agente de enlace celular enlazados a través de un enlazador no divisible, dichos conjugados, y métodos para hacer dichos conjugados - Google Patents

Método para activar las poblaciones de célula especificas utilizando conjugados maitansinoides del agente de enlace celular enlazados a través de un enlazador no divisible, dichos conjugados, y métodos para hacer dichos conjugados

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Publication number
ECSP066461A
ECSP066461A EC2006006461A ECSP066461A ECSP066461A EC SP066461 A ECSP066461 A EC SP066461A EC 2006006461 A EC2006006461 A EC 2006006461A EC SP066461 A ECSP066461 A EC SP066461A EC SP066461 A ECSP066461 A EC SP066461A
Authority
EC
Ecuador
Prior art keywords
conjugates
maitansinoid
methods
make
agent linked
Prior art date
Application number
EC2006006461A
Other languages
English (en)
Spanish (es)
Inventor
Rita Steeves
Robert Lutz
Ravi Chari
Hongsheng Xie
Yelena Kovtun
Original Assignee
Immunogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34467962&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP066461(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunogen Inc filed Critical Immunogen Inc
Publication of ECSP066461A publication Critical patent/ECSP066461A/es

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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EC2006006461A 2003-10-10 2006-03-28 Método para activar las poblaciones de célula especificas utilizando conjugados maitansinoides del agente de enlace celular enlazados a través de un enlazador no divisible, dichos conjugados, y métodos para hacer dichos conjugados ECSP066461A (es)

Applications Claiming Priority (2)

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US50990103P 2003-10-10 2003-10-10
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FR13C0068I1 (US07989598-20110802-C00010.png) 2014-01-17
CY1113984T1 (el) 2016-07-27
IL173625A (en) 2016-07-31
KR20060130552A (ko) 2006-12-19
US8163888B2 (en) 2012-04-24
KR101343676B1 (ko) 2013-12-20
US10844135B2 (en) 2020-11-24
NO2016001I2 (no) 2016-01-26
NO2016001I1 (no) 2016-01-26
SI1689846T1 (en) 2013-06-28
PL1689846T3 (pl) 2013-07-31
EP2612682A2 (en) 2013-07-10
JP2012006928A (ja) 2012-01-12
US20120226025A1 (en) 2012-09-06
EP1689846B1 (en) 2013-03-27
US20140154804A1 (en) 2014-06-05
AU2004282491C1 (en) 2011-06-30
LU92336I9 (US07989598-20110802-C00010.png) 2019-01-16
US8685920B2 (en) 2014-04-01
JP2019142864A (ja) 2019-08-29
US8088387B2 (en) 2012-01-03
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