DK0892791T3 - N-[[4-(5-methyl-3-phenylisoxazol-4-yl]-phenyl]-sulfonylpropylamid og dets natriumsalt som prodrugs for COX-2-inhibitorer - Google Patents

N-[[4-(5-methyl-3-phenylisoxazol-4-yl]-phenyl]-sulfonylpropylamid og dets natriumsalt som prodrugs for COX-2-inhibitorer

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Publication number
DK0892791T3
DK0892791T3 DK97921092T DK97921092T DK0892791T3 DK 0892791 T3 DK0892791 T3 DK 0892791T3 DK 97921092 T DK97921092 T DK 97921092T DK 97921092 T DK97921092 T DK 97921092T DK 0892791 T3 DK0892791 T3 DK 0892791T3
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DK
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Prior art keywords
sulfonylpropylamide
phenylisoxazol
cox
prodrugs
inhibitors
Prior art date
Application number
DK97921092T
Other languages
Danish (da)
English (en)
Inventor
John J Talley
James W Malecha
Stephen Bertenshaw
Matthew J Graneto
Jeffery S Carter
Jinglin Li
Srinivasan Nagarajan
David L Brown
Donald J Rogier Jr
Thomas D Penning
Ish K Khanna
Xiangdong Xu
Richard M Weier
Original Assignee
Searle & Co
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Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of DK0892791T3 publication Critical patent/DK0892791T3/da

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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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DK97921092T 1996-04-12 1997-04-11 N-[[4-(5-methyl-3-phenylisoxazol-4-yl]-phenyl]-sulfonylpropylamid og dets natriumsalt som prodrugs for COX-2-inhibitorer DK0892791T3 (da)

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