ID27574A - Inhibitor enzim - Google Patents
Inhibitor enzimInfo
- Publication number
- ID27574A ID27574A IDW20002052A ID20002052A ID27574A ID 27574 A ID27574 A ID 27574A ID W20002052 A IDW20002052 A ID W20002052A ID 20002052 A ID20002052 A ID 20002052A ID 27574 A ID27574 A ID 27574A
- Authority
- ID
- Indonesia
- Prior art keywords
- enzymer
- inhibitors
- enzymer inhibitors
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
- C08G65/48—Polymers modified by chemical after-treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0216—Solid or semisolid forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
- C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
- C08G65/3324—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof cyclic
- C08G65/3326—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof cyclic aromatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/92—Oral administration
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Polymers & Plastics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polyethers (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/041,196 US6066673A (en) | 1998-03-12 | 1998-03-12 | Enzyme inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
ID27574A true ID27574A (id) | 2001-04-12 |
Family
ID=21915262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW20002052A ID27574A (id) | 1998-03-12 | 1999-03-11 | Inhibitor enzim |
Country Status (18)
Country | Link |
---|---|
US (2) | US6066673A (id) |
EP (1) | EP1062264A2 (id) |
JP (1) | JP2002506099A (id) |
KR (1) | KR20010041860A (id) |
CN (1) | CN1300303A (id) |
AU (1) | AU2903799A (id) |
BR (1) | BR9909248A (id) |
CA (1) | CA2323496A1 (id) |
CO (1) | CO5080778A1 (id) |
HU (1) | HUP0102516A2 (id) |
ID (1) | ID27574A (id) |
IL (1) | IL138387A0 (id) |
NO (1) | NO20004550L (id) |
PE (1) | PE20000345A1 (id) |
PL (1) | PL364704A1 (id) |
SK (1) | SK13652000A3 (id) |
WO (1) | WO1999046316A2 (id) |
ZA (1) | ZA991975B (id) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7772455B1 (en) * | 1997-11-14 | 2010-08-10 | The Procter & Gamble Company | Disposable article providing improved management of bodily exudates |
US6291514B1 (en) | 1998-02-09 | 2001-09-18 | 3-Dimensional Pharmaceuticals, Inc. | Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors |
KR20010041799A (ko) * | 1998-03-12 | 2001-05-25 | 데이비드 엠 모이어 | 흡수 제품내 프로테아제 억제제 |
US6703536B2 (en) | 1998-03-12 | 2004-03-09 | The Procter & Gamble Company | Disposable absorbent article having a skin care composition containing an enzyme inhibitor |
CO5150202A1 (es) | 1998-12-31 | 2002-04-29 | Kimberly Clark Co | Composicion de tisu facial y metodo para usarla para el secuestro de irritantes de la piel de la secrecion nasal |
US6433243B1 (en) | 1999-02-26 | 2002-08-13 | Kimberly-Clark Worldwide, Inc. | Water permeable porous layer materials treated with surfactant-modified cyclodextrins |
US6479150B1 (en) | 1999-02-26 | 2002-11-12 | Kimberly-Clark Worldwide, Inc. | Layer materials treated with surfactant-modified hydrophobic odor control agents |
US6509284B1 (en) | 1999-02-26 | 2003-01-21 | Kimberly-Clark Worldwide, Inc. | Layer materials treated with surfacant-modified chelating agents |
ES2251376T3 (es) * | 1999-05-21 | 2006-05-01 | THE PROCTER & GAMBLE COMPANY | Articulo absorbente que tiene una composicion para el cuidado de la piel. |
JP2003509538A (ja) * | 1999-09-10 | 2003-03-11 | ザ、プロクター、エンド、ギャンブル、カンパニー | 酵素インヒビター |
US6541629B1 (en) * | 1999-09-10 | 2003-04-01 | The Procter & Gamble Company | Enzyme inhibitors |
AU7127100A (en) * | 1999-09-10 | 2001-04-10 | Procter & Gamble Company, The | Enzyme inhibitors |
US6841393B2 (en) | 1999-10-19 | 2005-01-11 | Kimberly-Clark Worldwide, Inc. | Selective removal of contaminants from a surface using colored particles and articles having magnets |
US6503761B1 (en) * | 1999-10-19 | 2003-01-07 | Kimberly-Clark Worldwide, Inc. | Selective removal of contaminants from a surface using articles having magnets |
US6464994B1 (en) * | 2000-01-19 | 2002-10-15 | Mentis Technologies, L.C. | Diaper dermatitis preventative medication and a method for making and using same |
US6693099B2 (en) * | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
US6376514B1 (en) * | 2000-10-17 | 2002-04-23 | The Procter & Gamble Co. | Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof |
US6746418B1 (en) | 2000-11-17 | 2004-06-08 | Playtex Products, Inc. | Methods of lubricating a tampon and a tampon lubricated thereby |
US7771735B2 (en) | 2000-12-22 | 2010-08-10 | Kimberly-Clark Worldwide, Inc. | Absorbent articles with compositions for reducing irritation response |
US20030022203A1 (en) * | 2001-04-23 | 2003-01-30 | Rajan Kumar | Cellular Arrays |
US7005557B2 (en) * | 2001-07-03 | 2006-02-28 | The Procter & Gamble Company | Film-forming compositions for protecting skin from body fluids and articles made therefrom |
US6852904B2 (en) | 2001-12-18 | 2005-02-08 | Kimberly-Clark Worldwide, Inc. | Cellulose fibers treated with acidic odor control agents |
US6767553B2 (en) | 2001-12-18 | 2004-07-27 | Kimberly-Clark Worldwide, Inc. | Natural fibers treated with acidic odor control/binder systems |
US6805875B2 (en) * | 2002-02-19 | 2004-10-19 | Jennifer F. Bartels | Composition and method for treating diaper rashes and skin irritations caused by acidic secretions |
CN1980948B (zh) | 2002-11-27 | 2011-08-10 | Dmi生物科学公司 | 治疗由增强磷酸化介导的疾病和病况 |
US7087559B2 (en) * | 2002-12-16 | 2006-08-08 | Avon Products, Inc. | Non-foaming cleaning and conditioning hair care compositions |
US20040122389A1 (en) * | 2002-12-23 | 2004-06-24 | Mace Tamara Lee | Use of hygroscopic treatments to enhance dryness in an absorbent article |
CN1886126A (zh) * | 2003-09-25 | 2006-12-27 | Dmi生物科学公司 | 利用n-酰基-l-天冬氨酸的方法和产品 |
US20060029567A1 (en) * | 2004-08-04 | 2006-02-09 | Bki Holding Corporation | Material for odor control |
US7265257B2 (en) * | 2004-08-10 | 2007-09-04 | Kimberly-Clark Worldwide, Inc. | Absorbent articles comprising a bodily exudate modifying agent and a film-forming skin care formulation |
US7642397B2 (en) * | 2004-08-10 | 2010-01-05 | Kimberly-Clark Worldwide, Inc. | Absorbent articles comprising a bodily exudate modifying agent and a skin care formulation |
US20060246383A1 (en) * | 2005-04-29 | 2006-11-02 | Kai-Kong Iu | Amphoteric stilbene composition |
US10265434B2 (en) | 2016-09-29 | 2019-04-23 | The Procter & Gamble Company | Absorbent articles comprising glyceride copolymers |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
FR2252351A2 (en) * | 1973-11-28 | 1975-06-20 | Air Liquide | Isolation of enzymes by selective extraction - partition of polyinhibitor-enzyme complex between water and polyethylene glycol |
GB1472700A (en) * | 1974-11-01 | 1977-05-04 | Ono Pharmaceutical Co | Guanidinobehzoic acid derivatives and process for preparing the same |
JPS5470241A (en) * | 1977-11-09 | 1979-06-05 | Ono Pharmaceut Co Ltd | Guanidinobenzoic acid derivative and its preparation |
JPS5634662A (en) * | 1979-08-31 | 1981-04-06 | Ono Pharmaceut Co Ltd | Guanidinobenzoic acid derivative and its preparation |
AU527371B2 (en) * | 1980-09-16 | 1983-03-03 | Torii & Co., Ltd. | Amidine |
FR2500825B1 (fr) * | 1981-02-27 | 1985-08-23 | Torii & Co Ltd | Nouveau carboxylate de 4-amidino-phenyle substitue, son procede de preparation et agent anti-complement en comprenant |
US4556560A (en) * | 1983-01-24 | 1985-12-03 | The Procter & Gamble Company | Methods for the treatment and prophylaxis of diaper rash and diaper dermatitis |
GB8500209D0 (en) * | 1985-01-04 | 1985-02-13 | Ceskoslovenska Akademie Ved | Synthetic polymeric drugs |
CS254355B1 (en) * | 1985-04-10 | 1988-01-15 | Vladimir Saudek | Soluble and biodegradatable copolymeres activated for bond of biologicaly active substances |
US4657537A (en) | 1985-05-15 | 1987-04-14 | The Procter & Gamble Company | Disposable absorbent articles |
PH26954A (en) | 1985-05-15 | 1992-12-03 | Procter & Gamble | Disposable absorbent articles |
US4746737A (en) * | 1985-07-26 | 1988-05-24 | Kowa Co., Ltd. | Phenyl guanidinobenzoate derivatives which have protease inhibitory activity |
US5247084A (en) * | 1985-11-12 | 1993-09-21 | Ono Pharmaceutical Co., Ltd. | Derivatives of p-guanidinobenzoic acid |
JPH0676373B2 (ja) * | 1985-12-27 | 1994-09-28 | エーザイ株式会社 | グアニジノ安息香酸エステル誘導体 |
US4873253A (en) * | 1987-03-30 | 1989-10-10 | Shosuke Okamoto | Phenylalanine derivative and proteinase inhibitor |
US4842593A (en) | 1987-10-09 | 1989-06-27 | The Procter & Gamble Company | Disposable absorbent articles for incontinent individuals |
US4948891A (en) * | 1988-05-24 | 1990-08-14 | Pfizer Inc. | Benzamide protease inhibitors |
US5162307A (en) * | 1988-09-09 | 1992-11-10 | Board Of Trustees Of The University Of Kentucky | Polymer bound elastase inhibitors |
FR2651125B1 (fr) * | 1989-08-23 | 1992-10-02 | Roussel Uclaf | Compositions pharmaceutiques de type "pates a l'eau". |
CA2032420A1 (en) * | 1989-12-22 | 1991-06-23 | Akira Okuyama | Guanidinobenzene derivatives |
ES2073502T3 (es) * | 1989-12-28 | 1995-08-16 | Snow Brand Milk Products Co Ltd | Derivados de isoquinolina y sus sales como inhibidores de la proteasa. |
EP0452179B1 (en) * | 1990-03-28 | 1996-06-12 | Nippon Oil And Fats Company, Limited | Polymer-combined drug for gastric treatment and a method for producing the drug |
US5372807A (en) * | 1990-05-14 | 1994-12-13 | University Of Medicine And Dentistry Of New Jersey | Polymers containing antifibrotic agents, compositions containing such polymers, and methods of preparation and use |
US5660822A (en) * | 1990-05-14 | 1997-08-26 | University Of Medicine & Dentistry Of N.J. | Polymers containing antifibrotic agents, compositions containing such polymers, and methods of preparation and use |
US5219564A (en) * | 1990-07-06 | 1993-06-15 | Enzon, Inc. | Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon |
JPH0446148A (ja) * | 1990-06-08 | 1992-02-17 | Asahi Chem Ind Co Ltd | 4―グアニジノ安息香酸フェニルエステル誘導体およびそれらを含有する蛋白分解酵素阻害剤 |
JP3051145B2 (ja) * | 1990-08-28 | 2000-06-12 | 住友製薬株式会社 | 新規なポリエチレングリコール誘導体修飾ペプチド |
IT1260468B (it) * | 1992-01-29 | 1996-04-09 | Metodo per mantenere l'attivita' di enzimi proteolitici modificati con polietilenglicole | |
WO1993024476A1 (en) * | 1992-06-04 | 1993-12-09 | Clover Consolidated, Limited | Water-soluble polymeric carriers for drug delivery |
ZA933926B (en) * | 1992-06-17 | 1994-01-03 | Amgen Inc | Polyoxymethylene-oxyethylene copolymers in conjuction with blomolecules |
CA2101361A1 (en) * | 1992-08-27 | 1994-02-28 | Robert A. Snow | Low diol polyalkylene oxide biologically active proteinaceous substances |
US5432178A (en) * | 1992-09-18 | 1995-07-11 | Ono Pharmaceutical Co., Ltd. | Amidinophenol derivatives |
WO1994013631A1 (en) * | 1992-12-10 | 1994-06-23 | Teikoku Chemical Industries Co., Ltd. | Propionic acid derivative |
US5449720A (en) * | 1993-05-24 | 1995-09-12 | Biotech Australia Pty Limited | Amplification of the VB12 uptake system using polymers |
US5840485A (en) * | 1993-05-27 | 1998-11-24 | Selectide Corporation | Topologically segregated, encoded solid phase libraries |
AU7097094A (en) * | 1993-06-01 | 1994-12-20 | Enzon, Inc. | Carbohydrate-modified polymer conjugates with erythropoietic activity |
GB9317618D0 (en) * | 1993-08-24 | 1993-10-06 | Royal Free Hosp School Med | Polymer modifications |
US5643575A (en) * | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
US5446090A (en) * | 1993-11-12 | 1995-08-29 | Shearwater Polymers, Inc. | Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules |
DE4342154A1 (de) * | 1993-12-10 | 1995-06-14 | Behringwerke Ag | Amidinophenylalaninderivate, Verfahren zu deren Herstellung, deren Verwendung und diese enthaltende Mittel als Antikoagulantien |
TW300883B (id) * | 1994-07-26 | 1997-03-21 | Kao Corp | |
US5783178A (en) * | 1994-11-18 | 1998-07-21 | Supratek Pharma. Inc. | Polymer linked biological agents |
GB9600272D0 (en) * | 1996-01-06 | 1996-03-06 | Univ Nottingham | Polymers |
US5869033A (en) * | 1996-04-12 | 1999-02-09 | Enviroderm Pharmaceuticals,Inc. | Method of preventing skin irritation caused by fecal enzymes |
-
1998
- 1998-03-12 US US09/041,196 patent/US6066673A/en not_active Expired - Fee Related
-
1999
- 1999-03-11 EP EP99909957A patent/EP1062264A2/en not_active Ceased
- 1999-03-11 JP JP2000535690A patent/JP2002506099A/ja not_active Withdrawn
- 1999-03-11 ID IDW20002052A patent/ID27574A/id unknown
- 1999-03-11 WO PCT/US1999/005314 patent/WO1999046316A2/en not_active Application Discontinuation
- 1999-03-11 HU HU0102516A patent/HUP0102516A2/hu unknown
- 1999-03-11 CN CN99806056A patent/CN1300303A/zh active Pending
- 1999-03-11 PL PL99364704A patent/PL364704A1/xx unknown
- 1999-03-11 ZA ZA9901975A patent/ZA991975B/xx unknown
- 1999-03-11 BR BR9909248-4A patent/BR9909248A/pt not_active IP Right Cessation
- 1999-03-11 IL IL13838799A patent/IL138387A0/xx unknown
- 1999-03-11 CA CA002323496A patent/CA2323496A1/en not_active Abandoned
- 1999-03-11 SK SK1365-2000A patent/SK13652000A3/sk unknown
- 1999-03-11 KR KR1020007010153A patent/KR20010041860A/ko active IP Right Grant
- 1999-03-11 AU AU29037/99A patent/AU2903799A/en not_active Abandoned
- 1999-03-12 PE PE1999000201A patent/PE20000345A1/es not_active Application Discontinuation
- 1999-03-12 CO CO99015434A patent/CO5080778A1/es unknown
-
2000
- 2000-02-16 US US09/504,444 patent/US6211186B1/en not_active Expired - Fee Related
- 2000-09-12 NO NO20004550A patent/NO20004550L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CO5080778A1 (es) | 2001-09-25 |
NO20004550L (no) | 2000-11-10 |
US6211186B1 (en) | 2001-04-03 |
US6066673A (en) | 2000-05-23 |
WO1999046316A3 (en) | 2000-03-23 |
CA2323496A1 (en) | 1999-09-16 |
BR9909248A (pt) | 2001-10-09 |
SK13652000A3 (sk) | 2001-04-09 |
ZA991975B (en) | 1999-09-27 |
IL138387A0 (en) | 2001-10-31 |
NO20004550D0 (no) | 2000-09-12 |
HUP0102516A2 (hu) | 2001-11-28 |
CN1300303A (zh) | 2001-06-20 |
KR20010041860A (ko) | 2001-05-25 |
JP2002506099A (ja) | 2002-02-26 |
PL364704A1 (en) | 2004-12-13 |
PE20000345A1 (es) | 2000-05-16 |
AU2903799A (en) | 1999-09-27 |
EP1062264A2 (en) | 2000-12-27 |
WO1999046316A2 (en) | 1999-09-16 |
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